ErbB2 (HER-2) Monoclonal Antibody (EP1045Y) | Invitrogen MA5-14488 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

ErbB2 (HER-2) Monoclonal Antibody (EP1045Y)

catalog :

MA5-14488

quantity :

1 mL

price :

US 1116.00

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

EP1045Y

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 6

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human; ready to use	KapucuoÄŸlu N, Bozkurt K, BaÅŸpÄ±nar Å, KoÃ§er M, EroÄŸlu H, Akdeniz R, et al. The clinicopathological and prognostic significance of CD24, CD44, CD133, ALDH1 expressions in invasive ductal carcinoma of the breast: CD44/CD24 expression in breast cancer. Pathol Res Pract. 2015;211:740-7 pubmed publisher
immunohistochemistry - paraffin section; human; 1:100; tbl 2	Qiu S, Wei X, Huang W, Wu M, Qin Y, Li Y, et al. Diagnostic and therapeutic strategy and the most efficient prognostic factors of breast malignant fibrous histiocytoma. Sci Rep. 2013;3:2529 pubmed publisher
immunohistochemistry; human; 1:50	Chen Y, Wang J, Wang X, Liu X, Li H, Lv Q, et al. STAT3, a Poor Survival Predicator, Is Associated with Lymph Node Metastasis from Breast Cancer. J Breast Cancer. 2013;16:40-9 pubmed publisher
immunohistochemistry; mouse	Cardiff R, Hubbard N, Engelberg J, Munn R, Miller C, Walls J, et al. Quantitation of fixative-induced morphologic and antigenic variation in mouse and human breast cancers. Lab Invest. 2013;93:480-97 pubmed publisher
immunohistochemistry; human; 1:50	Omran O. The prognostic value of breast cancer resistance protein (BCRB/ABCG2) expression in breast carcinomas. J Environ Pathol Toxicol Oncol. 2012;31:367-76 pubmed
immunocytochemistry; human; 1:200 immunohistochemistry; human; 1:100 western blot; human	Oak P, Kopp F, Thakur C, Ellwart J, Rapp U, Ullrich A, et al. Combinatorial treatment of mammospheres with trastuzumab and salinomycin efficiently targets HER2-positive cancer cells and cancer stem cells. Int J Cancer. 2012;131:2808-19 pubmed publisher

product information

Product Type :

Antibody

Product Name :

ErbB2 (HER-2) Monoclonal Antibody (EP1045Y)

Catalog # :

MA5-14488

Quantity :

1 mL

Price :

US 1116.00

Clonality :

Monoclonal

Host :

Rabbit

Reactivity :

Human

Applications :

Immunocytochemistry: 1:250, Immunohistochemistry (Frozen): 1:100, Immunohistochemistry (Paraffin): 1:100, Western Blot: 1:250

Species :

Human

Clone :

EP1045Y

Isotype :

IgG

Storage :

4° C

Description :

ErbB2 (HER2) is a receptor tyrosine kinase that is overexpressed in some breast tumors. Herceptin, used in treatment of metastatic Her2-positive cancer, is monoclonal antibody targeting this kinase.

Immunogen :

A synthetic peptide corresponding to the c-terminus of human Her2

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:250, Immunohistochemistry (Frozen): 1:100, Immunohistochemistry (Paraffin): 1:100, Western Blot: 1:250

Aliases :

avian erythroblastosis oncogene B 2; Avian erythroblastosis viral (v-erb-B2) oncogene homologue 2 (neuro/glioblastoma derived oncogene homolog); CD antigen CD340; CD340; c-erb B2/neu protein; c-erbB2; C-erbB-2; c-neu; epidermal growth factor receptor-related protein; erbb 2; ERBB2; erb-b2; Erbb-2; ErbB2 (pTyr1139); ErbB2 (pY1139); ErbB2 phospho Y1139; erb-b2 receptor tyrosine kinase 2; her 2; HER2; HER-2; HER-2/neu; herstatin; human epidermal growth factor receptor 2; Kiaa3023; metas; Metastatic lymph node gene 19 protein; mKIAA3023; MLN 19; MLN19; NEU; Neu oncogene; NEU proto-oncogene; neuro/glioblastoma derived oncogene homolog; neuroblastoma/glioblastoma derived oncogene homolog; NGL; p185erbB2; p185neu; phospho ErbB2; proto-oncogene c-ErbB-2; Proto-oncogene Neu; receptor tyrosine-protein kinase erbB-2; TKR1; Tyrosine kinase-type cell surface receptor HER2; v-erb-b2 avian erythroblastic leukemia viral oncogene 2; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2; v-erb-b2 avian erythroblastic leukemia viral oncoprotein 2; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)