Cytokeratin 8 Monoclonal Antibody (EP1628Y) | Invitrogen MA5-14476 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Cytokeratin 8 Monoclonal Antibody (EP1628Y)

catalog :

MA5-14476

quantity :

1 mL

price :

US 1436.00

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

EP1628Y

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 8

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; human; fig 4	Rogojanu R, Thalhammer T, Thiem U, Heindl A, Mesteri I, Seewald A, et al. Quantitative Image Analysis of Epithelial and Stromal Area in Histological Sections of Colorectal Cancer: An Emerging Diagnostic Tool. Biomed Res Int. 2015;2015:569071 pubmed publisher
immunohistochemistry; human; 1:200	Heindl A, Seewald A, Thalhammer T, Bises G, Schepelmann M, Uhrova H, et al. Automated REcognition of tissue-associated erythrocytes (ARETE)-a new tool in tissue cytometry. Cytometry A. 2013;83:363-74 pubmed publisher
immunocytochemistry; human western blot; human	Snider N, Leonard J, Kwan R, Griggs N, Rui L, Omary M. Glucose and SIRT2 reciprocally mediate the regulation of keratin 8 by lysine acetylation. J Cell Biol. 2013;200:241-7 pubmed publisher
immunohistochemistry; mouse	Lee E, Park J, Lee J, Oh S, Baek S, Kim B, et al. Characterization of the expression of cytokeratins 5, 8, and 14 in mouse thymic epithelial cells during thymus regeneration following acute thymic involution. Anat Cell Biol. 2011;44:14-24 pubmed publisher
	Jung M, Kowalczyk K, Hankins R, Bandi G, Kallakury B, Carrasquilla M, et al. Novel Paired Normal Prostate and Prostate Cancer Model Cell Systems Derived from African American Patients. Cancer Res Commun. 2022;2:1617-1625 pubmed publisher
	Schreurs O, Karatsaidis A, Balta M, Grung B, Hals E, Schenck K. Expression of keratins 8, 18, and 19 in epithelia of atrophic oral lichen planus. Eur J Oral Sci. 2020;128:7-17 pubmed publisher
	Chavez J, Schweppe D, Eng J, Zheng C, Taipale A, Zhang Y, et al. Quantitative interactome analysis reveals a chemoresistant edgotype. Nat Commun. 2015;6:7928 pubmed publisher
	Lian X, Selekman J, Bao X, Hsiao C, Zhu K, Palecek S. A small molecule inhibitor of SRC family kinases promotes simple epithelial differentiation of human pluripotent stem cells. PLoS ONE. 2013;8:e60016 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Cytokeratin 8 Monoclonal Antibody (EP1628Y)

Catalog # :

MA5-14476

Quantity :

1 mL

Price :

US 1436.00

Clonality :

Monoclonal

Host :

Rabbit

Reactivity :

Human

Applications :

Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:100

Species :

Human

Clone :

EP1628Y

Isotype :

IgG

Storage :

4 C

Description :

Cytokeratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. Cutokeratin 8 typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.

Immunogen :

A synthetic peptide corresponding to residues of the human CK18

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:100

Aliases :

AA960620; AL022697; AU019895; CARD2; cb186; CK8; CK-8; CYK8; CYKER; cytokeratin 8; cytokeratin 8 (370 AA); cytokeratin endo A; Cytokeratin-8; cytokeratin-A; DreK8; EndoA; etID33550.23; etID43142.23; etID43142.8; K2C8; K8; KERA; keratin 8; keratin 8, type II; keratin complex 2, basic, gene 8; keratin, type 2, gene 8; Keratin, type II cytoskeletal 8; keratin, type II cytoskeletal 8-like protein; keratin-8; KO; Krt-2.8; Krt2-8; krt8; LOW QUALITY PROTEIN: keratin, type II cytoskeletal 8; sb:cb186; type II cytokeratin A (no.8); type-II keratin Kb8; wu:fa20h05; wu:fa95h10; wu:fb96c06; zfk8; zf-K8

more info or order :

Invitrogen product webpage