Cytokeratin 5 Monoclonal Antibody (EP1601Y) | Invitrogen MA5-14473 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Cytokeratin 5 Monoclonal Antibody (EP1601Y)

catalog :

MA5-14473

quantity :

1 mL

price :

US 1040

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

EP1601Y

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

citations: 15

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human; fig 2	Eriksson P, Aine M, Veerla S, Liedberg F, SjÃ¶dahl G, HÃ¶glund M. Molecular subtypes of urothelial carcinoma are defined by specific gene regulatory systems. BMC Med Genomics. 2015;8:25 pubmed publisher
immunohistochemistry; mouse; 1:200	Zuo W, Zhang T, Wu D, Guan S, Liew A, Yamamoto Y, et al. p63(+)Krt5(+) distal airway stem cells are essential for lung regeneration. Nature. 2015;517:616-20 pubmed publisher
immunohistochemistry; human	Herfs M, Vargas S, Yamamoto Y, Howitt B, Nucci M, Hornick J, et al. A novel blueprint for 'top down' differentiation defines the cervical squamocolumnar junction during development, reproductive life, and neoplasia. J Pathol. 2013;229:460-8 pubmed publisher
immunohistochemistry; human	Herfs M, Yamamoto Y, Laury A, Wang X, Nucci M, McLaughlin Drubin M, et al. A discrete population of squamocolumnar junction cells implicated in the pathogenesis of cervical cancer. Proc Natl Acad Sci U S A. 2012;109:10516-21 pubmed publisher
immunohistochemistry; human	Sjödahl G, Lauss M, Lövgren K, Chebil G, Gudjonsson S, Veerla S, et al. A molecular taxonomy for urothelial carcinoma. Clin Cancer Res. 2012;18:3377-86 pubmed publisher
immunohistochemistry; human; 1:40	Kim B, Park E, Kwon I, Cho H, Park H, Kim K, et al. An immunohistochemical study of the origin of the solid strand in syringoma, using carcinoembryonic antigen, epithelial membrane antigen, and cytokeratin 5. Int J Dermatol. 2012;51:817-22 pubmed publisher
immunohistochemistry; mouse	Lee E, Park J, Lee J, Oh S, Baek S, Kim B, et al. Characterization of the expression of cytokeratins 5, 8, and 14 in mouse thymic epithelial cells during thymus regeneration following acute thymic involution. Anat Cell Biol. 2011;44:14-24 pubmed publisher
	Lyu H, Warren R, Gao S, Klinkhammer K, Yuan T, Zhang J, et al. Niche-mediated repair of airways is directed in an occupant-dependent manner. Cell Rep. 2022;41:111863 pubmed publisher
	Hong Y, Shan S, Gu Y, Huang H, Zhang Q, Han Y, et al. Malfunction of airway basal stem cells plays a crucial role in pathophysiology of tracheobronchopathia osteoplastica. Nat Commun. 2022;13:1309 pubmed publisher
	Mercurio L, Morelli M, Scarponi C, Scaglione G, Pallotta S, Albanesi C, et al. PI3Kδ Sustains Keratinocyte Hyperproliferation and Epithelial Inflammation: Implications for a Topically Druggable Target in Psoriasis. Cells. 2021;10: pubmed publisher
	Yuan T, Klinkhammer K, Lyu H, Gao S, Yuan J, Hopkins S, et al. Temporospatial Expression of Fgfr1 and 2 During Lung Development, Homeostasis, and Regeneration. Front Pharmacol. 2020;11:120 pubmed publisher
	Wang Y, Lu Y, Wu Y, Sun Y, Zhou Y, Ma Q, et al. Alveolar Differentiation Potency of Human Distal Airway Stem Cells Is Associated with Pulmonary Pathological Conditions. Stem Cells Int. 2019;2019:7123078 pubmed publisher
	Volckaert T, Yuan T, Yuan J, Boateng E, Hopkins S, Zhang J, et al. Hippo signaling promotes lung epithelial lineage commitment by curbing Fgf10 and β-catenin signaling. Development. 2019;146: pubmed publisher
	Tajpara P, Mildner M, Schmidt R, Vierhapper M, Matiasek J, Popow Kraupp T, et al. A Preclinical Model for Studying Herpes Simplex Virus Infection. J Invest Dermatol. 2019;139:673-682 pubmed publisher
	Volckaert T, Yuan T, Chao C, Bell H, Sitaula A, Szimmtenings L, et al. Fgf10-Hippo Epithelial-Mesenchymal Crosstalk Maintains and Recruits Lung Basal Stem Cells. Dev Cell. 2017;43:48-59.e5 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Cytokeratin 5 Monoclonal Antibody (EP1601Y)

Catalog # :

MA5-14473

Quantity :

1 mL

Price :

US 1040

Clonality :

Monoclonal

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

Immunocytochemistry: 5 µg/mL, Immunofluorescence: 5 µg/mL, Immunohistochemistry (Paraffin): 1:100, Immunohistochemistry: 1:50, Western Blot: 1:500

Species :

Human, Mouse

Clone :

EP1601Y

Isotype :

IgG

Storage :

4° C

Description :

Cytokeratin pan is part of a subfamily of intermediate filament proteins that are characterized by remarkable biochemical diversity, and represented in human epithelial tissues by at least 20 different polypeptides. Cytokeratins range in molecular weight between 40 kDa- 68 kDa, and an isoelectric pH between 4.9-7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays. The composition of cytokeratin pairs vary with the epithelial cell type, stage of differentiation, cellular growth environment, and disease state. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis.

Immunogen :

A synthetic peptide corresponding to residues on the C-term of human CK5

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 5 µg/mL, Immunofluorescence: 5 µg/mL, Immunohistochemistry (Paraffin): 1:100, Immunohistochemistry: 1:50, Western Blot: 1:500

Aliases :

3300001P10Rik; 58 kDa cytokeratin; AW146334; C DDD; C KRT5A; CK5; CK-5; cytokeratin 5; cytokeratin-5; DDD; DDD1; EBS2; epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types; K5; keratin 5; keratin 5 (epidermolysis bullosa simplex Dowling-Meara/Kobner/Weber-Cockayne types); keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types); keratin 5, type II; keratin complex 2, basic, gene 5; keratin, type II cytoskeletal 5; Keratin-5; Krt2-5; Krt5; KRT5A; Sak57; Tfip8; tuftelin interacting protein 8; type-II keratin Kb5