CD38 Monoclonal Antibody (38C03 (SPC32)) | Invitrogen MA5-14413 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD38 Monoclonal Antibody (38C03 (SPC32))

catalog :

MA5-14413

quantity :

500 µL

price :

US 410.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

38C03 (SPC32)

reactivity :

human, mouse

application :

western blot, immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section

citations: 10

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; human	Mueller A, Brieske C, Schinke S, Csernok E, Gross W, Hasselbacher K, et al. Plasma cells within granulomatous inflammation display signs pointing to autoreactivity and destruction in granulomatosis with polyangiitis. Arthritis Res Ther. 2014;16:R55 pubmed publisher
immunohistochemistry - paraffin section; human; 1:50; tbl 2	Nichele I, Zamo A, Bertolaso A, Bifari F, Tinelli M, Franchini M, et al. VR09 cell line: an EBV-positive lymphoblastoid cell line with in vivo characteristics of diffuse large B cell lymphoma of activated B-cell type. PLoS ONE. 2012;7:e52811 pubmed publisher
immunohistochemistry; human; 1:50	Bellan C, Amato T, Carmellini M, Onorati M, D Amuri A, Leoncini L, et al. Analysis of the IgVH genes in T cell-mediated and antibody-mediated rejection of the kidney graft. J Clin Pathol. 2011;64:47-53 pubmed publisher
immunohistochemistry; human	Horváth E, Mezei T, Pávai Z, Turcu M, Demian S, Toth E, et al. Diagnostic and differential diagnostic criteria of lymphoid neoplasms in bone marrow trephine biopsies: a study of 87 cases. Rom J Morphol Embryol. 2009;50:399-406 pubmed
	Liu Y, Su Y, Huang C, Tsai Y, Chen Y, Li P. Unusual bilateral kidney and duodenal plasmablastic lymphoma presentation in an elderly patient: A case report. Mol Clin Oncol. 2022;17:122 pubmed publisher
	Venturutti L, Teater M, Zhai A, Chadburn A, Babiker L, Kim D, et al. TBL1XR1 Mutations Drive Extranodal Lymphoma by Inducing a Pro-tumorigenic Memory Fate. Cell. 2020;182:297-316.e27 pubmed publisher
	Zhu L, Dai L, Zheng D, Mo Y, Ou Yang X, Wei X, et al. Upregulation of tumor necrosis factor receptor-associated factor 6 correlated with synovitis severity in rheumatoid arthritis. Arthritis Res Ther. 2012;14:R133 pubmed publisher
	Groen R, Noort W, Raymakers R, Prins H, Aalders L, Hofhuis F, et al. Reconstructing the human hematopoietic niche in immunodeficient mice: opportunities for studying primary multiple myeloma. Blood. 2012;120:e9-e16 pubmed publisher
	Sinanan A, Hunt N, Lewis M. Human adult craniofacial muscle-derived cells: neural-cell adhesion-molecule (NCAM; CD56)-expressing cells appear to contain multipotential stem cells. Biotechnol Appl Biochem. 2004;40:25-34 pubmed
	Bacher I, Zidar A, Kratzel M, Hohenegger M. Channelling of substrate promiscuity of the skeletal-muscle ADP-ribosyl cyclase isoform. Biochem J. 2004;381:147-54 pubmed

product information

Product Type :

Antibody

Product Name :

CD38 Monoclonal Antibody (38C03 (SPC32))

Catalog # :

MA5-14413

Quantity :

500 µL

Price :

US 410.00

Clonality :

Monoclonal

Host :

Mouse

Reactivity :

Human, Mouse

Applications :

Flow Cytometry: 1:2, Immunohistochemistry (Paraffin): 1:50-1:100, Western Blot: 1:50-1:200

Species :

Human, Mouse

Clone :

38C03 (SPC32)

Isotype :

IgG1

Storage :

4° C

Description :

CD38 (NAD+ glycohydrolase) is a type II transmembrane glycoprotein able to induce activation, proliferation and differentiation of mature lymphocytes and mediate apoptosis of myeloid and lymphoid progenitor cells. CD38 functions as a multi-catalytic ectoenzyme serving as ADP-ribosyl cyclase, cyclic ADP-ribose hydrolase and possibly NAD+ glycohydrolase or as a cell surface receptor. Antibodies to CD38 are useful in subtyping of lymphomas and leukemias, detection of plasma cells (i.e. identification of myelomas), and as a marker for activated B and T cells. CD38 participates in cell adhesion, signal transduction and calcium signaling. Further, CD38 is expressed at high levels in the pancreas, liver, kidney, malignant lymphoma and neuroblastoma. Diseases associated with CD38 dysfunction include chronic lymphocytic leukemia and Richter's Syndrome.

Immunogen :

Recombinant protein encoding the extracellular domain of human CD38

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:2, Immunohistochemistry (Paraffin): 1:50-1:100, Western Blot: 1:50-1:200

Aliases :

2'-phospho-ADP-ribosyl cyclase; 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase; 2'-phospho-cyclic-ADP-ribose transferase; ADPRC 1; ADPRC1; ADP-ribosyl cyclase 1; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; cADPr hydrolase 1; Cd38; CD38 antigen; CD38 antigen (ADP-ribosyl cyclase / cyclic ADP-ribose hydrolase); CD38 antigen (p45); CD38 antigen p45; CD38 molecule; CD38H; Cd38-rs1; cluster of differentiation 38; cyclic ADP-ribose hydrolase 1; ecto-nicotinamide adenine dinucleotide glycohydrolase; I-19; NAD(+) nucleosidase; NAD+ nucleosidase; NIM-R5 antigen; T10