MMP7 Monoclonal Antibody (ID2) | Invitrogen MA5-14215 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

MMP7 Monoclonal Antibody (ID2)

catalog :

MA5-14215

quantity :

500 µL

price :

US 450.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

ID2

reactivity :

human, rat, domestic sheep

application :

western blot, immunohistochemistry, immunocytochemistry

citations: 26

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; 1:50; tbl 2	Cid S, Eiró N, Gonzalez L, Béridze N, Vazquez J, Vizoso F. Expression and Clinical Significance of Metalloproteases and Their Inhibitors by Endothelial Cells From Invasive Breast Carcinomas. Clin Breast Cancer. 2016;16:e83-91 pubmed publisher
immunohistochemistry; human; 1:200	Kim G, Lee J, Choi Y, Lee K, Lee J, Nam J, et al. Expression of matrix metalloproteinases and their inhibitors in different immunohistochemical-based molecular subtypes of breast cancer. BMC Cancer. 2014;14:959 pubmed publisher
immunohistochemistry; human; 1:50	Suárez Roa M, Asbun Bojalil J, Ruiz Godoy L, Meneses García A. Immunoexpression of matrix metalloproteinases and their inhibitors in different areas of oral squamous cell carcinoma. Aust Dent J. 2012;57:300-7 pubmed publisher
immunohistochemistry; human; 1:50	Rubaci A, Kazancioglu H, Olgac V, Ak G. The roles of matrix metalloproteinases-2, -7, -10 and tissue inhibitor of metalloproteinase-1 in the pathogenesis of oral lichen planus. J Oral Pathol Med. 2012;41:689-96 pubmed publisher
immunohistochemistry; human; 1:50	Gonzalez L, Eiró N, Gonzalez L, Andicoechea A, Barbón E, García Muñiz J, et al. Effect of the expression of matrix metalloproteases and their tissue inhibitors on survival of patients with resectable colorectal cancer. Dig Dis Sci. 2012;57:2063-71 pubmed publisher
immunohistochemistry; human; 1.3 ug/ml	Brun J, Cortez A, Lesieur B, Uzan S, Rouzier R, Darai E. Expression of MMP-2, -7, -9, MT1-MMP and TIMP-1 and -2 has no prognostic relevance in patients with advanced epithelial ovarian cancer. Oncol Rep. 2012;27:1049-57 pubmed publisher
western blot; human; fig 6	Li L, Ying J, Li H, Zhang Y, Shu X, Fan Y, et al. The human cadherin 11 is a pro-apoptotic tumor suppressor modulating cell stemness through Wnt/?-catenin signaling and silenced in common carcinomas. Oncogene. 2012;31:3901-12 pubmed publisher
immunohistochemistry; human; 1:250	Ribeiro B, Ferreira de Araújo C, dos Santos B, de Almeida Freitas R. Immunohistochemical expression of matrix metalloproteinases 1, 2, 7, 9, and 26 in the calcifying cystic odontogenic tumor. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2011;112:609-15 pubmed publisher
immunohistochemistry; domestic sheep; 1:200	Ilhan F, Ulusoy Y, Haligur M. Matrix metalloproteinase expression in sheep with listerial meningoencephalitis. Res Vet Sci. 2012;92:269-72 pubmed publisher
immunohistochemistry; human; 1:10	Luukkaa H, Klemi P, Hirsimäki P, Vahlberg T, Kivisaari A, Kahari V, et al. Matrix metalloproteinase (MMP)-7 in salivary gland cancer. Acta Oncol. 2010;49:85-90 pubmed publisher
immunohistochemistry; human	Brun J, Cortez A, Commo F, Uzan S, Rouzier R, Darai E. Serous and mucinous ovarian tumors express different profiles of MMP-2, -7, -9, MT1-MMP, and TIMP-1 and -2. Int J Oncol. 2008;33:1239-46 pubmed
immunohistochemistry; human; 1:200	Rydlova M, Ludvikova M, Stankova I. Potential diagnostic markers in nodular lesions of the thyroid gland: an immunohistochemical study. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2008;152:53-9 pubmed
immunohistochemistry; human; 1:25	Dilek F, Topak N, Aktepe F, Sahin O, Türel K, Sahin D, et al. E-cadherin, beta-catenin adhesion complex and relation to matrilysin expression in pT3 rectosigmoid cancers. Pathol Res Pract. 2008;204:809-15 pubmed publisher
immunohistochemistry; rat western blot; rat; 1:2000	Gantus M, Nasciutti L, Cruz C, Persechini P, Martinez A. Modulation of extracellular matrix components by metalloproteinases and their tissue inhibitors during degeneration and regeneration of rat sural nerve. Brain Res. 2006;1122:36-46 pubmed
immunohistochemistry; human	Kirimlioglu H, Kirimlioglu V, Yilmaz S, Sagir V, Coban S, Turkmen E, et al. Role of matrix metalloproteinase-7 in colorectal adenomas. Dig Dis Sci. 2006;51:2068-72 pubmed
immunohistochemistry; human; 1:500	Odajima N, Betsuyaku T, Nasuhara Y, Itoh T, Fukuda Y, Senior R, et al. Extracellular matrix metalloproteinase inducer in interstitial pneumonias. Hum Pathol. 2006;37:1058-65 pubmed
immunohistochemistry; human; 1:130	Mylona E, Kapranou A, Mavrommatis J, Markaki S, Keramopoulos A, Nakopoulou L. The multifunctional role of the immunohistochemical expression of MMP-7 in invasive breast cancer. APMIS. 2005;113:246-55 pubmed
immunohistochemistry; rat; 1:1000	Scabilloni J, Wang L, Antonini J, Roberts J, Castranova V, Mercer R. Matrix metalloproteinase induction in fibrosis and fibrotic nodule formation due to silica inhalation. Am J Physiol Lung Cell Mol Physiol. 2005;288:L709-17 pubmed
	Uhlitz F, Bischoff P, Peidli S, Sieber A, Trinks A, L xfc then M, et al. Mitogen-activated protein kinase activity drives cell trajectories in colorectal cancer. EMBO Mol Med. 2021;13:e14123 pubmed publisher
	Altadill A, Eiró N, Gonz xe1 lez L, Andicoechea A, Fern xe1 ndez Francos S, Rodrigo L, et al. Relationship between Metalloprotease-7 and -14 and Tissue Inhibitor of Metalloprotease 1 Expression by Mucosal Stromal Cells and Colorectal Cancer Development in Inflammatory Bowel Disease. Biomedicines. 2021;9: pubmed publisher
	Han J, Gao B, Jin X, Xu Z, Li Z, Sun Y, et al. Small interfering RNA-mediated downregulation of beta-catenin inhibits invasion and migration of colon cancer cells in vitro. Med Sci Monit. 2012;18:BR273-80 pubmed
	Chang M, Chen C, Chen P, Chiang Y, Chen Y, Mao T, et al. Mesothelin enhances invasion of ovarian cancer by inducing MMP-7 through MAPK/ERK and JNK pathways. Biochem J. 2012;442:293-302 pubmed publisher
	Kirkegaard T, Hansen A, Bruun E, Brynskov J. Expression and localisation of matrix metalloproteinases and their natural inhibitors in fistulae of patients with Crohn's disease. Gut. 2004;53:701-9 pubmed
	Hogenboom S, Tuyp J, Espeel M, Koster J, Wanders R, Waterham H. Human mevalonate pyrophosphate decarboxylase is localized in the cytosol. Mol Genet Metab. 2004;81:216-24 pubmed
	Hogenboom S, Tuyp J, Espeel M, Koster J, Wanders R, Waterham H. Phosphomevalonate kinase is a cytosolic protein in humans. J Lipid Res. 2004;45:697-705 pubmed
	Maguen E, Zorapapel N, Zieske J, Ninomiya Y, Sado Y, Kenney M, et al. Extracellular matrix and matrix metalloproteinase changes in human corneas after complicated laser-assisted in situ keratomileusis (LASIK). Cornea. 2002;21:95-100 pubmed

product information

Product Type :

Antibody

Product Name :

MMP7 Monoclonal Antibody (ID2)

Catalog # :

MA5-14215

Quantity :

500 µL

Price :

US 450.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

Immunocytochemistry: Assay-dependent

Species :

Human

Clone :

ID2

Isotype :

IgG2b, kappa

Storage :

4° C

Description :

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22. 3.

Immunogen :

Recombinant human matrilysin (PUMP-1)

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: Assay-dependent

Aliases :

HGNC:7174; MAT; Matrilysin; matrilysin, uterine; matrin; matrix metallo protease; matrix metallopeptidase 7; matrix metallopeptidase 7 (matrilysin, uterine); matrix metalloproteinase 7; Matrix metalloproteinase 7 (matrilysin); matrix metalloproteinase 7 (matrilysin, uterine); matrix metalloproteinase-7; MMP; MMP 7; MMP7; Mmp-7; MMP-7 protein; MMPs; MPMM; MPSL1; PUMP 1; Pump 1 protease; PUMP1; PUMP-1; pump-1 protease; uterine matrilysin; uterine metalloproteinase