MMP3 Monoclonal Antibody (SL-1 ID3), Biotin | Invitrogen MA5-14199 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

MMP3 Monoclonal Antibody (SL-1 ID3), Biotin

catalog :

MA5-14199

quantity :

500 µL

price :

US 484

clonality :

monoclonal

host :

mouse

conjugate :

biotin

clone name :

SL-1 ID3

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry

citations: 2

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human; 1:250	Jin X, Jin X, Sohn Y, Yin J, Kim S, Joshi K, et al. Blockade of EGFR signaling promotes glioma stem-like cell invasiveness by abolishing ID3-mediated inhibition of p27(KIP1) and MMP3 expression. Cancer Lett. 2013;328:235-42 pubmed publisher
immunohistochemistry; human; 1:20	Halushka M, Cornish T, Lu J, Selvin S, Selvin E. Creation, validation, and quantitative analysis of protein expression in vascular tissue microarrays. Cardiovasc Pathol. 2010;19:136-46 pubmed publisher

product information

Product Type :

Antibody

Product Name :

MMP3 Monoclonal Antibody (SL-1 ID3), Biotin

Catalog # :

MA5-14199

Quantity :

500 µL

Price :

US 484

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human

Applications :

Immunocytochemistry: Assay-dependent, Western Blot: 2-4 µg/mL

Species :

Human

Clone :

SL-1 ID3

Isotype :

IgG1, kappa

Storage :

4° C

Description :

MMP3 (stromelysin-1) belongs to the peptidase M10A subfamily. It is secreted in its pro-protein form, and is activated by extracellular proteinase cleavage. MMP3 is capable of binding to zinc and calcium ions, and has metallo-endopeptidase activity. The active enzyme degrades collagen, gelatin, fibronectin, and laminin. It is involved in normal cellular processes such as wound repair and tissue remodeling. Mutations in the gene can result in coronary heart disease 6.

Immunogen :

APMA (4-Aminophenylmercuric acetate) activated Human stromelysin-1 (SL-1)

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: Assay-dependent, Western Blot: 2-4 µg/mL

Aliases :

CHDS6; EC 3.4.24.17; EMS-2; matrix metallo protease; matrix metallopeptidase 3; matrix metallopeptidase 3 (stromelysin 1, progelatinase); matrix metalloproteinase 3; matrix metalloproteinase 3 (stromelysin 1, progelatinase); matrix metalloproteinase 3 precursor; matrix metalloproteinase-3; metalloproteinase 3 receptor; MMP; MMP10; MMP3; MMP-3; MMP-3 protein; MMPs; progelatinase; proteoglycanase; SL-1; SLN1; SLN-1; STMY; STMY1; Str1; STR-1; stromelysin; stromelysin 1; Stromelysin1; stromelysin-1; Transin1; Transin-1