HGF Monoclonal Antibody (SBF5) | Invitrogen MA5-14160 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

HGF Monoclonal Antibody (SBF5)

catalog :

MA5-14160

quantity :

500 uL

price :

US 464.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

SBF5

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry

more info or order :

Invitrogen product webpage

citations: 5

Published Application/Species/Sample/Dilution	Reference
western blot; human; fig 1	Heynen G, Fonfara A, Bernards R. Resistance to targeted cancer drugs through hepatocyte growth factor signaling. Cell Cycle. 2014;13:3808-17 pubmed publisher
immunohistochemistry; human; 1 ug/ml ELISA; human; 0.5 ug/ml western blot; human	Dua R, Zhang J, Parry G, Penuel E. Detection of hepatocyte growth factor (HGF) ligand-c-MET receptor activation in formalin-fixed paraffin embedded specimens by a novel proximity assay. PLoS ONE. 2011;6:e15932 pubmed publisher
	Bauman J, Ohr J, Gooding W, Ferris R, Duvvuri U, Kim S, et al. Phase I Study of Ficlatuzumab and Cetuximab in Cetuximab-Resistant, Recurrent/Metastatic Head and Neck Cancer. Cancers (Basel). 2020;12: pubmed publisher
	Ko K, Lee J, Lee D, Nho B, Kim S. Hepatocyte Growth Factor (HGF) Promotes Peripheral Nerve Regeneration by Activating Repair Schwann Cells. Sci Rep. 2018;8:8316 pubmed publisher
	Bilezikci B, Demirhan B, Emiroglu R, Haberal M. Hepatocyte growth factor in hepatic allograft biopsies: an immunohistochemical study. Transplant Proc. 2003;35:3022-3 pubmed

product information

Product Type :

Antibody

Product Name :

HGF Monoclonal Antibody (SBF5)

Catalog # :

MA5-14160

Quantity :

500 uL

Price :

US 464.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human, Mouse

Applications :

Immunocytochemistry: 1:20-1:200, Western Blot: Assay-dependent

Species :

Human, Mouse

Clone :

SBF5

Isotype :

IgG1

Storage :

4 C

Description :

Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms.

Immunogen :

Recombinant human HGF protein

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:20-1:200, Western Blot: Assay-dependent

Aliases :

C230052L06Rik; DFNB39; Fibroblast derived tumor cytotoxic factor; fibroblast-derived tumor cytotoxic factor; F-TCF; hepatocyte growth factor; Hepatocyte growth factor (hepapoietin A; hepatocyte growth factor (hepapoietin A; scatter factor); Hepatocyte growth factor alpha chain; Hepatocyte growth factor beta chain; Hepatopoeitin A; hepatopoeitin-A; HepatopoietinA; hepatopoietin-A; Hgf; HGF/SF; HGFB; HPTA; Lung fibroblast derived mitogen; lung fibroblast-derived mitogen; NK1; NK2; Scatter factor; scatter factor); SF; SF/HGF

more info or order :

Invitrogen product webpage