Cytokeratin 6A Monoclonal Antibody (LHK6B) | Invitrogen MA5-14127 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Cytokeratin 6A Monoclonal Antibody (LHK6B)

catalog :

MA5-14127

quantity :

500 uL

price :

US 359.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

LHK6B

reactivity :

human, mouse

application :

immunohistochemistry

citations: 18

Reference
Takahashi T, Asano Y, Sugawara K, Yamashita T, Nakamura K, Saigusa R, et al. Epithelial Fli1 deficiency drives systemic autoimmunity and fibrosis: Possible roles in scleroderma. J Exp Med. 2017;214:1129-1151 pubmed publisher
Mitchell D, Israr M, Alam S, Dinello D, Kishel J, Jia R, et al. HIV nucleoside reverse transcriptase inhibitors efavirenz and tenofovir change the growth and differentiation of primary gingival epithelium. HIV Med. 2014;15:196-202 pubmed publisher
Veniaminova N, Vagnozzi A, Kopinke D, Do T, Murtaugh L, Maillard I, et al. Keratin 79 identifies a novel population of migratory epithelial cells that initiates hair canal morphogenesis and regeneration. Development. 2013;140:4870-80 pubmed publisher
Sjödahl G, Lövgren K, Lauss M, Patschan O, Gudjonsson S, Chebil G, et al. Toward a molecular pathologic classification of urothelial carcinoma. Am J Pathol. 2013;183:681-91 pubmed publisher
Cheng C, Leferovich J, Zhang X, Bedelbaeva K, Gourevitch D, Hatcher C, et al. Keratin gene expression profiles after digit amputation in C57BL/6 vs. regenerative MRL mice imply an early regenerative keratinocyte activated-like state. Physiol Genomics. 2013;45:409-21 pubmed publisher
Carretero M, Guerrero Aspizua S, Del Rio M. Bioengineered skin humanized model of psoriasis. Methods Mol Biol. 2013;961:305-23 pubmed publisher
Makarova G, Bette M, Schmidt A, Jacob R, Cai C, Rodepeter F, et al. Epidermal growth factor-induced modulation of cytokeratin expression levels influences the morphological phenotype of head and neck squamous cell carcinoma cells. Cell Tissue Res. 2013;351:59-72 pubmed publisher
Mitchell D, Israr M, Alam S, Kishel J, Dinello D, Meyers C. Effect of the HIV nucleoside reverse transcriptase inhibitor zidovudine on the growth and differentiation of primary gingival epithelium. HIV Med. 2012;13:276-90 pubmed publisher
Sakamoto K, Aragaki T, Morita K, Kawachi H, Kayamori K, Nakanishi S, et al. Down-regulation of keratin 4 and keratin 13 expression in oral squamous cell carcinoma and epithelial dysplasia: a clue for histopathogenesis. Histopathology. 2011;58:531-42 pubmed publisher
Garcia M, Larcher F, Hickerson R, Baselga E, Leachman S, Kaspar R, et al. Development of skin-humanized mouse models of pachyonychia congenita. J Invest Dermatol. 2011;131:1053-60 pubmed publisher
Israr M, Mitchell D, Alam S, Dinello D, Kishel J, Meyers C. The HIV protease inhibitor lopinavir/ritonavir (Kaletra) alters the growth, differentiation and proliferation of primary gingival epithelium. HIV Med. 2011;12:145-56 pubmed publisher
Murray S, Oram K, Gridley T. Multiple functions of Snail family genes during palate development in mice. Development. 2007;134:1789-97 pubmed
Yang L, Shirakata Y, Shudou M, Dai X, Tokumaru S, Hirakawa S, et al. New skin-equivalent model from de-epithelialized amnion membrane. Cell Tissue Res. 2006;326:69-77 pubmed
Yin Y, Bai R, Russell R, Beildeck M, Xie Z, Kopelovich L, et al. Characterization of medroxyprogesterone and DMBA-induced multilineage mammary tumors by gene expression profiling. Mol Carcinog. 2005;44:42-50 pubmed
Chang Y, Liu H, Wang W, Lee D, Tsai S. A study of cytokeratin profiles in localized cutaneous amyloids. Arch Dermatol Res. 2004;296:83-8 pubmed
Sawchuk D, Mansilla Soto J, Alarcon C, Singha N, Langen H, Bianchi M, et al. Ku70/Ku80 and DNA-dependent protein kinase catalytic subunit modulate RAG-mediated cleavage: implications for the enforcement of the 12/23 rule. J Biol Chem. 2004;279:29821-31 pubmed
Hale L, Buckley R, Puck J, Patel D. Abnormal development of thymic dendritic and epithelial cells in human X-linked severe combined immunodeficiency. Clin Immunol. 2004;110:63-70 pubmed
Hale L, Markert M. Corticosteroids regulate epithelial cell differentiation and Hassall body formation in the human thymus. J Immunol. 2004;172:617-24 pubmed

product information

Product Type :

Antibody

Product Name :

Cytokeratin 6A Monoclonal Antibody (LHK6B)

Catalog # :

MA5-14127

Quantity :

500 uL

Price :

US 359.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human, Mouse

Applications :

Immunohistochemistry: Assay-dependent

Species :

Human, Mouse

Clone :

LHK6B

Isotype :

IgG2a

Storage :

4 C

Description :

Keratins 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation-related keratins). Keratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyperproliferative situations. Epidermal injury results in activation of keratinocytes which express CK6 and CK16. CK6 is strongly expressed in about 75% of head and neck squamous cell carcinomas. Expression of CK6 is particularly associated with differentiation.

Immunogen :

A synthetic peptide (GSSTIKYTTTS) from the C-terminus of human keratin 6

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry: Assay-dependent

Aliases :

2310016L08Rik; 60-kDa keratin; CK6A; CK-6A; CK6C; CK-6C; CK6D; CK-6D; CK-6E; cytokeratin 6A; cytokeratin 6C; cytokeratin 6D; cytokeratin-6A; cytokeratin-6C; Cytokeratin-6D; cytokeratin-6E; Hom s 5; K6A; K6a keratin; K6C; K6D; kamp-keratin derived antimicrobial peptide; KDAMP; Ker2; keratin 6A; keratin 6A, , type II; keratin 6A, type II; keratin complex 2, basic, gene 6a; keratin complex 2, basic, gene 6c; keratin complex 2, gene 6a; keratin K6; keratin K6h; keratin, epidermal type II, K6A; keratin, type II cytoskeletal 6A; keratin, type II cytoskeletal 6C; Keratin-6A; keratin-6-alpha; keratin-6C; Krt2-6; Krt2-6a; Krt2-6c; Krt6; KRT6A; KRT6C; KRT6D; LOC683313; mK6[a]; MK6a; mK6-alpha; PC3; similar to keratin complex 2, basic, gene 6a; type-II keratin Kb12; type-II keratin Kb6