CD36 Monoclonal Antibody (185-1G2) | Invitrogen MA5-14112 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD36 Monoclonal Antibody (185-1G2)

catalog :

MA5-14112

quantity :

500 uL

price :

US 460.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

185-1G2

reactivity :

human, mouse

application :

immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section, blocking or activating experiments

more info or order :

Invitrogen product webpage

citations: 15

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; fig 5	Pardee A, Yano H, Weinstein A, Ponce A, Ethridge A, Normolle D, et al. Route of antigen delivery impacts the immunostimulatory activity of dendritic cell-based vaccines for hepatocellular carcinoma. J Immunother Cancer. 2015;3:32 pubmed publisher
immunohistochemistry; human; 10 ug/ml	Hromatka B, Ngeleza S, Adibi J, Niles R, Tshefu A, Fisher S. Histopathologies, immunolocalization, and a glycan binding screen provide insights into Plasmodium falciparum interactions with the human placenta. Biol Reprod. 2013;88:154 pubmed publisher
flow cytometry; human	Taront S, Dieudonné A, Blanchard S, Jeannin P, Lassalle P, Delneste Y, et al. Implication of scavenger receptors in the interactions between diesel exhaust particles and immature or mature dendritic cells. Part Fibre Toxicol. 2009;6:9 pubmed publisher
flow cytometry; human	Klein M, Gittis A, Su H, Makobongo M, Moore J, Singh S, et al. The cysteine-rich interdomain region from the highly variable plasmodium falciparum erythrocyte membrane protein-1 exhibits a conserved structure. PLoS Pathog. 2008;4:e1000147 pubmed publisher
immunohistochemistry; human	Martens J, Kzhyshkowska J, Falkowski Hansen M, Schledzewski K, Gratchev A, Mansmann U, et al. Differential expression of a gene signature for scavenger/lectin receptors by endothelial cells and macrophages in human lymph node sinuses, the primary sites of regional metastasis. J Pathol. 2006;208:574-89 pubmed
blocking or activating experiments; human; 5 ug/ml	Short S, Derrien A, Narsimhan R, Lawler J, Ingber D, Zetter B. Inhibition of endothelial cell migration by thrombospondin-1 type-1 repeats is mediated by beta1 integrins. J Cell Biol. 2005;168:643-53 pubmed
	Moiseeva V, Cisneros A, Sica V, Deryagin O, Lai Y, Jung S, et al. Senescence atlas reveals an aged-like inflamed niche that blunts muscle regeneration. Nature. 2023;613:169-178 pubmed publisher
	Min H, Moon J, Lee S, Lee A, Lee C, Lee J, et al. Expanded IL-22+ Group 3 Innate Lymphoid Cells and Role of Oxidized LDL-C in the Pathogenesis of Axial Spondyloarthritis with Dyslipidaemia. Immune Netw. 2021;21:e43 pubmed publisher
	Huang C, Chou C, Chen W, Yang J, Lee W, Chen J, et al. Empagliflozin Ameliorates Free Fatty Acid Induced-Lipotoxicity in Renal Proximal Tubular Cells via the PPARγ/CD36 Pathway in Obese Mice. Int J Mol Sci. 2021;22: pubmed publisher
	Kitaura A, Nishinaka T, Hamasaki S, Hatipoglu O, Wake H, Nishibori M, et al. Advanced glycation end-products reduce lipopolysaccharide uptake by macrophages. PLoS ONE. 2021;16:e0245957 pubmed publisher
	Huang L, Chambliss K, Gao X, Yuhanna I, Behling Kelly E, Bergaya S, et al. SR-B1 drives endothelial cell LDL transcytosis via DOCK4 to promote atherosclerosis. Nature. 2019;569:565-569 pubmed publisher
	Hamasaki S, Kobori T, Yamazaki Y, Kitaura A, Niwa A, Nishinaka T, et al. Effects of scavenger receptors-1 class A stimulation on macrophage morphology and highly modified advanced glycation end product-protein phagocytosis. Sci Rep. 2018;8:5901 pubmed publisher
	DuSablon A, Parks J, Whitehurst K, Estes H, Chase R, Vlahos E, et al. EphrinA1-Fc attenuates myocardial ischemia/reperfusion injury in mice. PLoS ONE. 2017;12:e0189307 pubmed publisher
	Isenberg J, Ridnour L, Dimitry J, Frazier W, Wink D, Roberts D. CD47 is necessary for inhibition of nitric oxide-stimulated vascular cell responses by thrombospondin-1. J Biol Chem. 2006;281:26069-80 pubmed
	Chen X, Doffek K, Sugg S, Shilyansky J. Phosphatidylserine regulates the maturation of human dendritic cells. J Immunol. 2004;173:2985-94 pubmed

product information

Product Type :

Antibody

Product Name :

CD36 Monoclonal Antibody (185-1G2)

Catalog # :

MA5-14112

Quantity :

500 uL

Price :

US 460.00

Clonality :

Monoclonal

Purity :

Protein A/G

Host :

Mouse

Reactivity :

Human, Mouse

Applications :

Flow Cytometry: 0.5-1 ug/test, Immunocytochemistry: 1:10-1:100, Immunohistochemistry (Frozen): Assay-dependent

Species :

Human, Mouse

Clone :

185-1G2

Isotype :

IgG2a, kappa

Storage :

4 C

Description :

CD36, also known as scavenger receptor class B member 3, is a protein that is expressed on the surface of various cell types, including macrophages, platelets, and adipocytes. It plays a role in lipid metabolism, inflammation, and atherosclerosis, and is involved in the recognition and uptake of various ligands such as oxidized low-density lipoproteins, long-chain fatty acids, and apoptotic cells. CD36 is also implicated in the pathogenesis of malaria. The protein encoded by this gene serves as a receptor for thrombospondin in platelets and various cell lines, and is the fourth major glycoprotein of the platelet surface. It binds to collagen, thrombospondin, anionic phospholipids, and oxidized LDL, and directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants have been found for this gene. Diseases associated with CD36 include Platelet Glycoprotein IV Deficiency and Coronary Heart Disease 7.

Immunogen :

Stimulated human leukocytes

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.5-1 ug/test, Immunocytochemistry: 1:10-1:100, Immunohistochemistry (Frozen): Assay-dependent

Aliases :

adipocyte membrane protein; BDPLT10; Cd36; CD36 antigen; CD36 antigen (collagen type I receptor, thrombospondin receptor); CD36 molecule; CD36 molecule (thrombospondin receptor); CD36 protein; CHDS7; cluster determinant 36; collagen type I receptor thrombospondin receptor; collagen type I receptor, thrombospondin receptor; FAT; FAT/CD36; fatty acid translocase; fatty acid translocase/CD36; fatty acid transport protein; glycoprotein IIIb; GP3B; GP4; GPIIIB; GPIV; I79_011940; Leukocyte differentiation antigen CD36; PAS IV; PAS4; PAS-4; PAS-4 protein; PASIV; Platelet collagen receptor; Platelet glycoprotein 4; platelet glycoprotein IV; Scarb3; scavenger receptor class B, member 3; SR-B3; Thrombospondin receptor

more info or order :

Invitrogen product webpage