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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
MUC1 Monoclonal Antibody (E29)
catalog :
MA5-14077
quantity :
500 uL
price :
US 414.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
E29
reactivity :
human, mouse
application :
immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, blocking or activating experiments
more info or order :
Invitrogen product webpage
citations: 23
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human; 1:50; loading ...; tbl 3
Han G, Yu W, Chu J, Liu Y, Jiang Y, Li Y, et al. Oncocytic papillary renal cell carcinoma: A clinicopathological and genetic analysis and indolent clinical course in 14 cases. Pathol Res Pract. 2017;213:1-6 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:50
Sajin M, Luchian M, Hodorogea Prisăcaru A, Dumitru A, Pătraşcu O, Costache D, et al. Trichilemmal carcinoma - a rare cutaneous malignancy: report of two cases. Rom J Morphol Embryol. 2014;55:687-91 pubmed
  • immunohistochemistry; human; 1:200
Pizzi M, Pennelli G, Merante Boschin I, Fassan M, Pelizzo M, Rugge M. Pancreatic mucinous cystic tumor in Turner syndrome: How a tumor bends to a genetic disease. Int J Surg Case Rep. 2013;4:1028-31 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:200; tbl 2
Qiu S, Wei X, Huang W, Wu M, Qin Y, Li Y, et al. Diagnostic and therapeutic strategy and the most efficient prognostic factors of breast malignant fibrous histiocytoma. Sci Rep. 2013;3:2529 pubmed publisher
  • immunohistochemistry; human; tbl 1
Zhao Y, Li W, Lang R, Yang Y, Gao X, Zheng Y, et al. Primary acinic cell carcinoma of the breast: a case report and review of the literature. Int J Surg Pathol. 2014;22:177-81 pubmed publisher
  • immunohistochemistry; human; 1:500
Yin W, Li J, Chan J. Sporadic haemangioblastoma of the kidney with rhabdoid features and focal CD10 expression: report of a case and literature review. Diagn Pathol. 2012;7:39 pubmed publisher
  • immunohistochemistry; human; 1:200
Kim B, Park E, Kwon I, Cho H, Park H, Kim K, et al. An immunohistochemical study of the origin of the solid strand in syringoma, using carcinoembryonic antigen, epithelial membrane antigen, and cytokeratin 5. Int J Dermatol. 2012;51:817-22 pubmed publisher
  • immunohistochemistry; human; 1:400
Chang I, Chen H, Ma M, Huang W. Anaplastic large cell lymphoma with paraneoplastic leukocytosis: a clinicopathological analysis of five cases. APMIS. 2011;119:794-801 pubmed publisher
  • immunohistochemistry; human; 1:100
Schittenhelm J, Nagel C, Meyermann R, Beschorner R. Atypical teratoid/rhabdoid tumors may show morphological and immunohistochemical features seen in choroid plexus tumors. Neuropathology. 2011;31:461-7 pubmed publisher
  • immunohistochemistry; human; 1:30
Guyotat J, Metellus P, Giorgi R, Barrie M, Jouvet A, Fevre Montange M, et al. Infratentorial ependymomas: prognostic factors and outcome analysis in a multi-center retrospective series of 106 adult patients. Acta Neurochir (Wien). 2009;151:947-60 pubmed publisher
  • immunohistochemistry; human; 1:200
Boldorini R, Panzarasa G, Girardi P, Monga G. Primary choroid plexus papilloma of the sacral nerve roots. J Neurosurg Spine. 2009;10:51-3 pubmed publisher
  • immunohistochemistry; human
Russell M, Flynt F, Harroff A, Fadare O. Dedifferentiated Liposarcoma of the Retroperitoneum with Extensive Leiomyosarcomatous Differentiation and beta-Human Chorionic Gonadotropin Production. Sarcoma. 2008;2008:658090 pubmed publisher
  • immunohistochemistry; human
Gurbuz Y, Kose N, Aydin O, Ozturk M. An immunohistochemical profile of giant cell carcinoma of the larynx. Auris Nasus Larynx. 2007;34:413-6 pubmed
  • blocking or activating experiments; human; 5 ug/ml
Doi M, Yokoyama A, Kondo K, Ohnishi H, Ishikawa N, Hattori N, et al. Anti-tumor effect of the anti-KL-6/MUC1 monoclonal antibody through exposure of surface molecules by MUC1 capping. Cancer Sci. 2006;97:420-9 pubmed
  • immunohistochemistry; human; 1:20
Bikmaz K, Cosar M, Kurtkaya Yapicier O, Iplikcioglu A, Gokduman C. Recurrent solitary fibrous tumour in the cerebellopontine angle. J Clin Neurosci. 2005;12:829-32 pubmed
Huisman B, Cankat M, Bosse T, Vahrmeijer A, Rissmann R, Burggraaf J, et al. Integrin αvβ6 as a Target for Tumor-Specific Imaging of Vulvar Squamous Cell Carcinoma and Adjacent Premalignant Lesions. Cancers (Basel). 2021;13: pubmed publisher
Tonyali S, Yazici S, Yeşilırmak A, Ergen A. The Ewing's Sarcoma Family of Tumors of Urinary Bladder: A Case Report and Review of the Literature. Balkan Med J. 2016;33:462-6 pubmed publisher
Cetin S, Kir G, Yilmaz M. Thyroid Paraganglioma Diagnosed by Fine-Needle Aspiration Biopsy, Correlated With Histopathological Findings: Report of a Case. Diagn Cytopathol. 2016;44:643-7 pubmed publisher
Vermeulen J, van Brussel A, van der Groep P, Morsink F, Bult P, van der Wall E, et al. Immunophenotyping invasive breast cancer: paving the road for molecular imaging. BMC Cancer. 2012;12:240 pubmed publisher
Dagli M, Eryilmaz A, Acar A, Kulacoglu S, Akmansu H. Collagenous fibroma (desmoplastic fibroblastoma). Yonsei Med J. 2004;45:941-3 pubmed
Kocer B, Soran A, Kiyak G, Erdogan S, Eroglu A, Bozkurt B, et al. Prognostic significance of mucin expression in gastric carcinoma. Dig Dis Sci. 2004;49:954-64 pubmed
Kocer B, Ulas M, Ustundag Y, Erdogan S, Karabeyoglu M, Yldrm O, et al. A confirmatory report for the close interaction of Helicobacter pylori with gastric epithelial MUC5AC expression. J Clin Gastroenterol. 2004;38:496-502 pubmed
Liu B, Lague J, Nunes D, Toselli P, Oppenheim F, Soares R, et al. Expression of membrane-associated mucins MUC1 and MUC4 in major human salivary glands. J Histochem Cytochem. 2002;50:811-20 pubmed
product information
Product Type :
Antibody
Product Name :
MUC1 Monoclonal Antibody (E29)
Catalog # :
MA5-14077
Quantity :
500 uL
Price :
US 414.00
Clonality :
Monoclonal
Purity :
protein A
Host :
Mouse
Reactivity :
Human, Mouse
Applications :
Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:400-1:800
Species :
Human, Mouse
Clone :
E29
Isotype :
IgG2a, kappa
Storage :
4 C
Description :
MUC1 (Mucin 1, Episialin, MAM-6, CA 15-3, PEM and EMA) is a large cell surface mucin glycoprotein expressed by most glandular and ductal epithelial cells and some hematopoietic cell lineages. MUC1 is a transmembrane glycoprotein with a large mucin-like extracellular domain that matures through several intermediate forms generated by proteolysis, and sequential addition and processing of numerous O-linked glycans that are heavily sialylated. MUC1 is highly polymorphic and each allele encodes a product that contains a different number of repeats (between 30 and 90) leading to large differences in molecular weight of the protein. MUC1 is expressed on most secretory epithelium, including mammary gland and some hematopoietic cells, and is expressed abundantly in >90% breast carcinomas and metastases. Transgenic MUC1 has been shown to associate with all four cebB receptors and localize with erbB1 (EGFR) in lactating glands. The MUC1 gene contains seven exons and produces several different alternatively spliced variants. Overexpression, aberrant intracellular localization, and changes in glycosylation of the MUC1 protein have been associated with carcinomas. Multiple alternatively spliced transcript variants that encode different isoforms of the MUC1 gene have been reported, but the full-length nature of only some has been determined. Transgenic MUC-1 has been shown to associate with all four cebB receptors and localize with erbB1 (EGFR) in lactating glands.
Immunogen :
Delipidated extract of human milk fat globule membranes
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:400-1:800
Aliases :
ADMCKD; ADMCKD1; Breast carcinoma-associated antigen DF3; CA 15-3; Cancer antigen 15-3; carcinoma-associated mucin; CD227; DF3 antigen; EMA; Episialin; H23 antigen; H23AG; J19; KL-6; Krebs von den Lungen-6; MAM6; MCD; MCKD; MCKD1; Medullary cystic kidney disease, autosomal dominant; Muc1; MUC-1; MUC-1/SEC; MUC-1/X; MUC1/ZD; MUC1-alpha; MUC1-beta; MUC1-CT; MUC1-NT; mucin 1, cell surface associated; mucin 1, transmembrane; Mucin1; mucin-1; Mucin-1 subunit alpha; Mucin-1 subunit beta; peanut-reactive urinary mucin; PEM; PEMT; Polymorphic epithelial mucin; PUM; tumor associated epithelial mucin; tumor-associated epithelial membrane antigen; Tumor-associated mucin
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA