product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD23 Monoclonal Antibody (1B12)
catalog :
MA5-14054
quantity :
500 uL
price :
US 484.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1B12
reactivity :
human
application :
immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
Invitrogen product webpage
citations: 9
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human; 1:10; loading ...
van den Brand M, Balagué O, van Cleef P, Groenen P, Hebeda K, de Jong D, et al. A subset of low-grade B cell lymphomas with a follicular growth pattern but without a BCL2 translocation shows features suggestive of nodal marginal zone lymphoma. J Hematop. 2016;9:3-8 pubmed
  • immunohistochemistry; human
Lorenzi L, Tabellini G, Vermi W, Moratto D, Porta F, Notarangelo L, et al. Occurrence of nodular lymphocyte-predominant hodgkin lymphoma in hermansky-pudlak type 2 syndrome is associated to natural killer and natural killer T cell defects. PLoS ONE. 2013;8:e80131 pubmed publisher
  • immunohistochemistry - paraffin section; human; loading ...; fig 2d
  • immunohistochemistry; human
Lorenzi L, Lonardi S, Petrilli G, Tanda F, Bella M, Laurino L, et al. Folliculocentric B-cell-rich follicular dendritic cells sarcoma: a hitherto unreported morphological variant mimicking lymphoproliferative disorders. Hum Pathol. 2012;43:209-15 pubmed publisher
  • immunohistochemistry; human; 1:20
Vermi W, Lonardi S, Bosisio D, Uguccioni M, Danelon G, Pileri S, et al. Identification of CXCL13 as a new marker for follicular dendritic cell sarcoma. J Pathol. 2008;216:356-64 pubmed publisher
  • immunohistochemistry; human
Lefebvre C, Fabre B, Vettier C, Rabin L, Florin A, Wang J, et al. Composite splenic marginal zone lymphoma and mantle cell lymphoma arising from 2 independent B-cell clones. Hum Pathol. 2007;38:660-7 pubmed
  • immunohistochemistry; human
Asaad N, Abd El Wahed M, Dawoud M. Diagnosis and prognosis of B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma (B-CLL/SLL) and mantle cell lymphoma (MCL). J Egypt Natl Canc Inst. 2005;17:279-90 pubmed
  • immunohistochemistry; human
Smit L, Hallaert D, Spijker R, de Goeij B, Jaspers A, Kater A, et al. Differential Noxa/Mcl-1 balance in peripheral versus lymph node chronic lymphocytic leukemia cells correlates with survival capacity. Blood. 2007;109:1660-8 pubmed
  • immunohistochemistry; human; 1:20
Vermi W, Facchetti F, Riboldi E, Heine H, Scutera S, Stornello S, et al. Role of dendritic cell-derived CXCL13 in the pathogenesis of Bartonella henselae B-rich granuloma. Blood. 2006;107:454-62 pubmed
Oz Puyan F, Bilgi S, Unlu E, Yalcin O, Altaner S, Demir M, et al. Inflammatory pseudotumor of the spleen with EBV positivity: report of a case. Eur J Haematol. 2004;72:285-91 pubmed
product information
Product Type :
Antibody
Product Name :
CD23 Monoclonal Antibody (1B12)
Catalog # :
MA5-14054
Quantity :
500 uL
Price :
US 484.00
Clonality :
Monoclonal
Host :
Mouse
Reactivity :
Human
Applications :
Immunohistochemistry (Paraffin): 1:20-1:40
Species :
Human
Clone :
1B12
Isotype :
IgG1, kappa
Storage :
4 C
Description :
CD23 is a 45 kDa glycoprotein which is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts. The CD23 molecule is identical to the low affinity IgE receptor found on B cells. Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic lymphocyctic leukaemia and some cases of centroblastic/centrocytic lymphoma. CD23 is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts. Functionally, CD23 is involved in B cell growth and differentiation, and IgE production. Further, CD23 has a soluble form that is a potent mitogenic factor. Diseases associated with CD23 dysfunction include chronic conjunctivitis and chronic lymphocytic leukemia.
Immunogen :
Recombinant external domain of CD23 protein
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry (Paraffin): 1:20-1:40
Aliases :
BLAST-2; CD23; CD23 antigen; CD23A; CLEC4J; C-type lectin domain family 4 member J; C-type lectin domain family 4, member J; Fc epsilon receptor II; FC epsilon RII; Fc fragment of IgE receptor II; Fc fragment of IgE, low affinity II, receptor for (CD23); Fc receptor alpha multiple ligand receptor; Fc receptor, IgE, low affinity II, alpha polypeptide; Fcalpha muR; Fcalpha RII; Fce2; fc-epsilon-RII; FCER2; Fcer2a; FceRII; IGEBF; Immunoglobulin E-binding factor; immunoglobulin epsilon-chain; low affinity immunoglobulin epsilon Fc receptor; Low affinity immunoglobulin epsilon Fc receptor membrane-bound form; Low affinity immunoglobulin epsilon Fc receptor soluble form; low-affinity IgE receptor; Ly-42; lymphocyte IgE receptor
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA