Moesin Monoclonal Antibody (38/87) | Invitrogen MA5-14043 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Moesin Monoclonal Antibody (38/87)

catalog :

MA5-14043

quantity :

500 µL

price :

US 436.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

38/87

reactivity :

human, rat, bovine

application :

western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section

citations: 17

Reference
Shao B, Yago T, Coghill P, Klopocki A, Mehta D souza P, Schmidtke D, et al. Signal-dependent slow leukocyte rolling does not require cytoskeletal anchorage of P-selectin glycoprotein ligand-1 (PSGL-1) or integrin ?L?2. J Biol Chem. 2012;287:19585-98 pubmed publisher
Schlecht N, Brandwein Gensler M, Smith R, Kawachi N, Broughel D, Lin J, et al. Cytoplasmic ezrin and moesin correlate with poor survival in head and neck squamous cell carcinoma. Head Neck Pathol. 2012;6:232-43 pubmed publisher
Zhang Y, Dong J, Zhu X, Wang W, Yang Q. The effect of sphingomyelin synthase 2 (SMS2) deficiency on the expression of drug transporters in mouse brain. Biochem Pharmacol. 2011;82:287-94 pubmed publisher
Brem E, Thudium K, Khubchandani S, Tsai P, Olejniczak S, Bhat S, et al. Distinct cellular and therapeutic effects of obatoclax in rituximab-sensitive and -resistant lymphomas. Br J Haematol. 2011;153:599-611 pubmed publisher
Olejniczak S, Blickwedehl J, Belicha Villanueva A, Bangia N, Riaz W, Mavis C, et al. Distinct molecular mechanisms responsible for bortezomib-induced death of therapy-resistant versus -sensitive B-NHL cells. Blood. 2010;116:5605-14 pubmed publisher
Giusiano S, Secq V, Carcopino X, Carpentier S, Andrac L, Lavaut M, et al. Immunohistochemical profiling of node negative breast carcinomas allows prediction of metastatic risk. Int J Oncol. 2010;36:889-98 pubmed
Washington A, Gibot S, Acevedo I, Gattis J, Quigley L, Feltz R, et al. TREM-like transcript-1 protects against inflammation-associated hemorrhage by facilitating platelet aggregation in mice and humans. J Clin Invest. 2009;119:1489-501 pubmed publisher
Takamatsu H, Espinoza J, Lu X, Qi Z, Okawa K, Nakao S. Anti-moesin antibodies in the serum of patients with aplastic anemia stimulate peripheral blood mononuclear cells to secrete TNF-alpha and IFN-gamma. J Immunol. 2009;182:703-10 pubmed
Olejniczak S, Hernandez Ilizaliturri F, Clements J, Czuczman M. Acquired resistance to rituximab is associated with chemotherapy resistance resulting from decreased Bax and Bak expression. Clin Cancer Res. 2008;14:1550-60 pubmed publisher
Torer N, Kayaselcuk F, Nursal T, Yildirim S, Tarim A, Noyan T, et al. Adhesion molecules as prognostic markers in pancreatic adenocarcinoma. J Surg Oncol. 2007;96:419-23 pubmed
Takamatsu H, Feng X, Chuhjo T, Lu X, Sugimori C, Okawa K, et al. Specific antibodies to moesin, a membrane-cytoskeleton linker protein, are frequently detected in patients with acquired aplastic anemia. Blood. 2007;109:2514-20 pubmed
Madan R, Brandwein Gensler M, Schlecht N, Elias K, Gorbovitsky E, Belbin T, et al. Differential tissue and subcellular expressionof ERM proteins in normal and malignant tissues: cytoplasmic ezrin expression has prognostic signficance for head and neck squamous cell carcinoma. Head Neck. 2006;28:1018-27 pubmed
Köbel M, Gradhand E, Zeng K, Schmitt W, Kriese K, Lantzsch T, et al. Ezrin promotes ovarian carcinoma cell invasion and its retained expression predicts poor prognosis in ovarian carcinoma. Int J Gynecol Pathol. 2006;25:121-30 pubmed
Saotome I, Curto M, McClatchey A. Ezrin is essential for epithelial organization and villus morphogenesis in the developing intestine. Dev Cell. 2004;6:855-64 pubmed
Brown M, Nijhara R, Hallam J, Gignac M, Yamada K, Erlandsen S, et al. Chemokine stimulation of human peripheral blood T lymphocytes induces rapid dephosphorylation of ERM proteins, which facilitates loss of microvilli and polarization. Blood. 2003;102:3890-9 pubmed
Sanchez Carbayo M, Socci N, Charytonowicz E, Lu M, Prystowsky M, Childs G, et al. Molecular profiling of bladder cancer using cDNA microarrays: defining histogenesis and biological phenotypes. Cancer Res. 2002;62:6973-80 pubmed
Johnson M, Miyata H, Vinters H. Ezrin and moesin expression within the developing human cerebrum and tuberous sclerosis-associated cortical tubers. Acta Neuropathol. 2002;104:188-96 pubmed

product information

Product Type :

Antibody

Product Name :

Moesin Monoclonal Antibody (38/87)

Catalog # :

MA5-14043

Quantity :

500 µL

Price :

US 436.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Bovine, Human, Rat

Applications :

Immunohistochemistry (Paraffin): 0.25-0.5 µg/mL, Immunoprecipitation: 2 µg/mL, Western Blot: 1-2 µg/mL

Species :

Bovine, Human, Rat

Clone :

38/87

Isotype :

IgG1, kappa

Storage :

4° C

Description :

Moesin, a member of the talin-4. 1 superfamily, is a linking protein of the submembraneous actin cytoskeleton. It is expressed in macrophages, lymphocytes, fibroblastic, endothelial, epithelial, and neuronal cell lines but not in blood cells. It is involved in cell adhesion, migration, and organization of cell surface structures.

Immunogen :

Moesin purified from cow uterus

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 0.25-0.5 µg/mL, Immunoprecipitation: 2 µg/mL, Western Blot: 1-2 µg/mL

Aliases :

C78546; epididymis luminal protein 70; HEL70; Membrane-organizing extension spike protein; MGC137877 protein; moesin; MSN