This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Bcl-X Monoclonal Antibody (2H12), Biotin
catalog :
MA5-14008
quantity :
500µL
price :
US 399.00
clonality :
monoclonal
host :
mouse
conjugate :
biotin
clone name :
2H12
reactivity :
human, mouse, rat, pig
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
citations: 6
Published Application/Species/Sample/DilutionReference
  • western blot; human
Schulze Bergkamen H, Ehrenberg R, Hickmann L, Vick B, Urbanik T, Schimanski C, et al. Bcl-x(L) and Myeloid cell leukaemia-1 contribute to apoptosis resistance of colorectal cancer cells. World J Gastroenterol. 2008;14:3829-40 pubmed
  • immunohistochemistry; human; 0.5 ug/ml
Shaknovich R, Basso K, Bhagat G, Mansukhani M, Hatzivassiliou G, Murty V, et al. Identification of rare Epstein-Barr virus infected memory B cells and plasma cells in non-monomorphic post-transplant lymphoproliferative disorders and the signature of viral signaling. Haematologica. 2006;91:1313-20 pubmed
Wang J, Wei Q, Wang C, Hill W, Hess D, Dong Z. Minocycline up-regulates Bcl-2 and protects against cell death in mitochondria. J Biol Chem. 2004;279:19948-54 pubmed
Sharif M, Whitehouse A, Sharman P, Perry M, Adams M. Increased apoptosis in human osteoarthritic cartilage corresponds to reduced cell density and expression of caspase-3. Arthritis Rheum. 2004;50:507-15 pubmed
Dong Z, Wang J. Hypoxia selection of death-resistant cells. A role for Bcl-X(L). J Biol Chem. 2004;279:9215-21 pubmed
Ferrero E, Belloni D, Contini P, Foglieni C, Ferrero M, Fabbri M, et al. Transendothelial migration leads to protection from starvation-induced apoptosis in CD34+CD14+ circulating precursors: evidence for PECAM-1 involvement through Akt/PKB activation. Blood. 2003;101:186-93 pubmed
product information
Product Type :
Antibody
Product Name :
Bcl-X Monoclonal Antibody (2H12), Biotin
Catalog # :
MA5-14008
Quantity :
500µL
Price :
US 399.00
Clonality :
Monoclonal
Purity :
protein A
Host :
Mouse
Reactivity :
Human, Mouse, Porcine, Rat
Applications :
Flow Cytometry: Assay Dependent, Immunofluorescence: Assay Dependent, Immunohistochemistry (Paraffin): 2-4 µg/mL
Species :
Human, Mouse, Porcine, Rat
Clone :
2H12
Isotype :
IgG2a
Storage :
4° C
Description :
Bcl-X has two isoforms, Bcl-XL (long) a 241 amino acid protein and Bcl-XS (short) a 178 amino acid protein lacking a 63 amino acid domain that is well conserved among members of the Bcl-2 family.
Immunogen :
A synthetic peptide, aa 3-14 (Cys-QSNRELVVDFLS) of human Bcl-X protein. This amino acid sequence is shared by human and murine bcl-X protein.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: Assay Dependent, Immunofluorescence: Assay Dependent, Immunohistochemistry (Paraffin): 2-4 µg/mL
Aliases :
apoptosis regulator Bcl-X, bcl-2-like protein 1, bcl2-L-1
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
www.thermofisher.com
800-678-5599
headquarters: USA