| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; mouse; 1:1000; loading ...; fig 4d
| Cho J, Lee J, Kim H, Lee H, Fang Z, Kwon H, et al. Ethyl Acetate Fraction of Amomum villosum var. xanthioides Attenuates Hepatic Endoplasmic Reticulum Stress-Induced Non-Alcoholic Steatohepatitis via Improvement of Antioxidant Capacities. Antioxidants (Basel). 2021;10: pubmed publisher |
- immunohistochemistry; human; 1:500; loading ...; fig 8e
- western blot; human; loading ...; fig 2d
| Loureiro J, Raimundo L, Calheiros J, Carvalho C, Barcherini V, Lima N, et al. Targeting p53 for Melanoma Treatment: Counteracting Tumour Proliferation, Dissemination and Therapeutic Resistance. Cancers (Basel). 2021;13: pubmed publisher |
| Wang Y, Lv J, Cheng Y, DU J, Chen D, Li C, et al. Apoptosis induced by Ginkgo biloba (EGb761) in melanoma cells is Mcl-1-dependent. PLoS ONE. 2015;10:e0124812 pubmed publisher |
- immunohistochemistry - paraffin section; rat; 1:50
| Mohamed H, el Swefy S, Hasan R, HASAN A. Neuroprotective effect of resveratrol in diabetic cerebral ischemic-reperfused rats through regulation of inflammatory and apoptotic events. Diabetol Metab Syndr. 2014;6:88 pubmed publisher |
| Xu H, Zhu G, Tian Y. Protective effects of trimetazidine on bone marrow mesenchymal stem cells viability in an ex vivo model of hypoxia and in vivo model of locally myocardial ischemia. J Huazhong Univ Sci Technolog Med Sci. 2012;32:36-41 pubmed publisher |
- western blot; rat; 1:1500
| Xinxing W, Hong F, Rui Z, Yun Z, Jingbo G, Lingjia Q. Phosphorylated nerve growth factor-induced clone B (NGFI-B) translocates from the nucleus to mitochondria of stressed rat cardiomyocytes and induces apoptosis. Stress. 2012;15:545-53 pubmed publisher |
- western blot; rat; 1:1000
| Baquedano E, García Cáceres C, Diz Chaves Y, Lagunas N, Calmarza Font I, Azcoitia I, et al. Prenatal stress induces long-term effects in cell turnover in the hippocampus-hypothalamus-pituitary axis in adult male rats. PLoS ONE. 2011;6:e27549 pubmed publisher |
- immunocytochemistry; human; 1.6 ug/ml
| Kim B, Hong S. Sequential caspase-2 and caspase-8 activation is essential for saikosaponin a-induced apoptosis of human colon carcinoma cell lines. Apoptosis. 2011;16:184-97 pubmed publisher |
| Kim B, Maeng K, Lee K, Hong S. Combined treatment with the Cox-2 inhibitor niflumic acid and PPAR? ligand ciglitazone induces ER stress/caspase-8-mediated apoptosis in human lung cancer cells. Cancer Lett. 2011;300:134-44 pubmed publisher |
| Choi B, Lee C. Cell cycle arrest and cytochrome c-mediated apoptotic induction by MCS-5A is associated with up-regulation of p16(INK4a) in HL-60 cells. Bioorg Med Chem Lett. 2010;20:3880-4 pubmed publisher |
- immunohistochemistry; mouse
| Perumalsamy L, Nagala M, Sarin A. Notch-activated signaling cascade interacts with mitochondrial remodeling proteins to regulate cell survival. Proc Natl Acad Sci U S A. 2010;107:6882-7 pubmed publisher |
- immunohistochemistry; rat; 1:100
| Giris M, Erbil Y, Depboylu B, Mete O, Turkoglu U, Abbasoglu S, et al. Heme oxygenase-1 prevents hyperthyroidism induced hepatic damage via an antioxidant and antiapoptotic pathway. J Surg Res. 2010;164:266-75 pubmed publisher |
- immunocytochemistry; rat; 1:500
- western blot; rat; 1:1000
| Delgado Rubín A, Chowen J, Argente J, Frago L. Growth hormone-releasing peptide 6 protection of hypothalamic neurons from glutamate excitotoxicity is caspase independent and not mediated by insulin-like growth factor I. Eur J Neurosci. 2009;29:2115-24 pubmed publisher |
- immunoprecipitation; human
| Kim B, Choi Y, Han Y, Yun Y, Hong S. N,N-dimethyl phytosphingosine induces caspase-8-dependent cytochrome c release and apoptosis through ROS generation in human leukemia cells. Toxicol Appl Pharmacol. 2009;239:87-97 pubmed publisher |
- immunohistochemistry; rat; 1:500
- western blot; rat; 1:5000
| García Cáceres C, Lechuga Sancho A, Argente J, Frago L, Chowen J. Death of hypothalamic astrocytes in poorly controlled diabetic rats is associated with nuclear translocation of apoptosis inducing factor. J Neuroendocrinol. 2008;20:1348-60 pubmed publisher |
- western blot; human; 1.6 ug/ml
| Kim B, Chung H. Desferrioxamine (DFX) induces apoptosis through the p38-caspase8-Bid-Bax pathway in PHA-stimulated human lymphocytes. Toxicol Appl Pharmacol. 2008;228:24-31 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:50; fig 2A
| Takei H, Buckleair L, Powell S. Immunohistochemical expression of apoptosis regulating proteins and sex hormone receptors in meningiomas. Neuropathology. 2008;28:62-8 pubmed |
- immunohistochemistry; rat
- western blot; rat
| Chen X, Chen Y, Bi Y, Fu N, Shan C, Wang S, et al. Preventive cardioprotection of erythropoietin against doxorubicin-induced cardiomyopathy. Cardiovasc Drugs Ther. 2007;21:367-74 pubmed |
| Kim B, Chung H. Hypoxia/reoxygenation induces apoptosis through a ROS-mediated caspase-8/Bid/Bax pathway in human lymphocytes. Biochem Biophys Res Commun. 2007;363:745-50 pubmed |
- immunocytochemistry; human
| Parikh N, Koshy C, Dhayabaran V, Perumalsamy L, Sowdhamini R, Sarin A. The N-terminus and alpha-5, alpha-6 helices of the pro-apoptotic protein Bax, modulate functional interactions with the anti-apoptotic protein Bcl-xL. BMC Cell Biol. 2007;8:16 pubmed |
- western blot; mouse; 1:1000
| Ray S, Chatterjee A. Influence of glutathione on the induction of chromosome aberrations, delay in cell cycle kinetics and cell cycle regulator proteins in irradiated mouse bone marrow cells. Int J Radiat Biol. 2007;83:347-54 pubmed |
- immunocytochemistry; rat; 1:100
| Chai Y, Niu L, Sun X, Ding J, Hu G. Iptakalim protects PC12 cell against H2O2-induced oxidative injury via opening mitochondrial ATP-sensitive potassium channel. Biochem Biophys Res Commun. 2006;350:307-14 pubmed |
| Mu Q, Wang X, Huang K, Xia B, Bi S, Kong Y. THUMPD3-AS1 inhibits ovarian cancer cell apoptosis through the miR-320d/ARF1 axis. FASEB J. 2024;38:e23772 pubmed publisher |
| Xiao J, Wan F, Tian L, Li Y. Tumor suppressor miR-520a inhibits cell growth by negatively regulating PI3K/AKT signaling pathway in acute myeloid leukemia. Adv Clin Exp Med. 2024;33:729-738 pubmed publisher |
| Yusupova M, Ankawa R, Yosefzon Y, Meiri D, Bachelet I, Fuchs Y. Apoptotic dysregulation mediates stem cell competition and tissue regeneration. Nat Commun. 2023;14:7547 pubmed publisher |
| Schroer J, Warm D, De Rosa F, Luhmann H, Sinning A. Activity-dependent regulation of the BAX/BCL-2 pathway protects cortical neurons from apoptotic death during early development. Cell Mol Life Sci. 2023;80:175 pubmed publisher |
| Zhao L, Fan J, Zhang C, Zhang Z, Dong J. CircRANBP17 modulated KDM1A to regulate neuroblastoma progression by sponging miR-27b-3p. Open Med (Wars). 2023;18:20230672 pubmed publisher |
| Zhou H, Yun X, Shu Y, Xu K. Aspirin increases the efficacy of gemcitabine in pancreatic cancer by modulating the PI3K/AKT/mTOR signaling pathway and reversing epithelial‑mesenchymal transition. Oncol Lett. 2023;25:101 pubmed publisher |
| Tregub P, Malinovskaya N, Hilazheva E, Morgun A, Kulikov V. Permissive hypercapnia and hypercapnic hypoxia inhibit signaling pathways of neuronal apoptosis in ischemic/hypoxic rats. Mol Biol Rep. 2023;50:2317-2333 pubmed publisher |
| Gendy A, El Gazar A, Ragab G, Al Mokaddem A, El Haddad A, Selim H, et al. Possible Implication of Nrf2, PPAR-γ and MAPKs Signaling in the Protective Role of Mangiferin against Renal Ischemia/Reperfusion in Rats. Pharmaceuticals (Basel). 2022;16: pubmed publisher |
| Natrus L, Osadchuk Y, Lisakovska O, Roch T, Babel N, Klys Y, et al. Regulation of the apoptosis/autophagy switch by propionic acid in ventromedial hypothalamus of rats with type 2 diabetes mellitus. Heliyon. 2022;8:e11529 pubmed publisher |
| Arab H, Abd El Aal H, Alsufyani S, El Sheikh A, Arafa E, Ashour A, et al. Topiramate Reprofiling for the Attenuation of Cadmium-Induced Testicular Impairment in Rats: Role of NLRP3 Inflammasome and AMPK/mTOR-Linked Autophagy. Pharmaceuticals (Basel). 2022;15: pubmed publisher |
| Su Y, Xu J, Chen S, Feng J, Li J, Lei Z, et al. Astragaloside IV protects against ischemia/reperfusion (I/R)-induced kidney injury based on the Keap1-Nrf2/ARE signaling pathway. Transl Androl Urol. 2022;11:1177-1188 pubmed publisher |
| Ye Y, Chang Z, Wang P, Wang Y, Liang J, Chen C, et al. Infarct-preconditioning exosomes of umbilical cord mesenchymal stem cells promoted vascular remodeling and neurological recovery after stroke in rats. Stem Cell Res Ther. 2022;13:378 pubmed publisher |
| Varlamova E, Gudkov S, Plotnikov E, Turovsky E. Size-Dependent Cytoprotective Effects of Selenium Nanoparticles during Oxygen-Glucose Deprivation in Brain Cortical Cells. Int J Mol Sci. 2022;23: pubmed publisher |
| Long X, Wu H, Zhou Y, Wan Y, Kan X, Gong J, et al. Preventive Effect of Limosilactobacillus fermentum SCHY34 on Lead Acetate-Induced Neurological Damage in SD Rats. Front Nutr. 2022;9:852012 pubmed publisher |
| Kisacam M, Ambarcıoğlu P, Yakan A. Calcium fructoborate regulate colon cancer (Caco-2) cytotoxicity through modulation of apoptosis. J Biochem Mol Toxicol. 2022;36:e23021 pubmed publisher |
| Ashour H, Hashem H, Khowailed A, Rashed L, Hassan R, Soliman A. Necrostatin-1 mitigates renal ischaemia-reperfusion injury - time dependent - via aborting the interacting protein kinase (RIPK-1)-induced inflammatory immune response. Clin Exp Pharmacol Physiol. 2022;49:501-514 pubmed publisher |
| Mart xed nez Iglesias O, Carrera I, Naidoo V, Cacabelos R. AntiGan: An Epinutraceutical Bioproduct with Antitumor Properties in Cultured Cell Lines. Life (Basel). 2022;12: pubmed publisher |
| Jenner A, Pe xf1 a Blanco A, Salvador Gallego R, Ugarte Uribe B, Zollo C, Ganief T, et al. DRP1 interacts directly with BAX to induce its activation and apoptosis. EMBO J. 2022;41:e108587 pubmed publisher |
| Chen P, Lei J, Chen F, Zhou B. Ameliorative effect of urolithin A on d-gal-induced liver and kidney damage in aging mice via its antioxidative, anti-inflammatory and antiapoptotic properties. RSC Adv. 2020;10:8027-8038 pubmed publisher |
| Liu Y, Yang Y, Zhang L, Lin J, Li B, Yang M, et al. LncRNA ASAP1-IT1 enhances cancer cell stemness via regulating miR-509-3p/YAP1 axis in NSCLC. Cancer Cell Int. 2021;21:572 pubmed publisher |
| Chen J, Xu Q, Zhang W, Zhen Y, Cheng F, Hua G, et al. MiR-203-3p inhibits the oxidative stress, inflammatory responses and apoptosis of mice podocytes induced by high glucose through regulating Sema3A expression. Open Life Sci. 2020;15:939-950 pubmed publisher |
| Yu C, Tang W, Lu R, Tao Y, Ren T, Gao Y. Human Adipose-derived mesenchymal stem cells promote lymphocyte apoptosis and alleviate atherosclerosis via miR-125b-1-3p/BCL11B signal axis. Ann Palliat Med. 2021;10:2123-2133 pubmed publisher |
| Chong S, Iskandar K, Lai J, Qu J, Raman D, Valentin R, et al. Serine-70 phosphorylated Bcl-2 prevents oxidative stress-induced DNA damage by modulating the mitochondrial redox metabolism. Nucleic Acids Res. 2020;48:12727-12745 pubmed publisher |
| Al Serwi R, Othman G, Attia M, Enan E, El Sherbiny M, Mahmoud S, et al. Enhancement of Cisplatin Cytotoxicity by Cu(II)-Mn(II) Schiff Base Tetradentate Complex in Human Oral Squamous Cell Carcinoma. Molecules. 2020;25: pubmed publisher |
| Liang F, Fu X, Li Y, Han F. Desoxyrhapontigenin attenuates neuronal apoptosis in an isoflurane-induced neuronal injury model by modulating the TLR-4/cyclin B1/Sirt-1 pathway. AMB Express. 2020;10:175 pubmed publisher |
| Jabeen A, Sharma A, Gupta I, Kheraldine H, Vranic S, Al Moustafa A, et al. Elaeagnus angustifolia Plant Extract Inhibits Epithelial-Mesenchymal Transition and Induces Apoptosis via HER2 Inactivation and JNK Pathway in HER2-Positive Breast Cancer Cells. Molecules. 2020;25: pubmed publisher |
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| Mai N, Yamaguchi Y, Choijookhuu N, Matsumoto J, Nanashima A, Takagi H, et al. Photodynamic Therapy Using a Novel Phosphorus Tetraphenylporphyrin Induces an Anticancer Effect via Bax/Bcl-xL-related Mitochondrial Apoptosis in Biliary Cancer Cells. Acta Histochem Cytochem. 2020;53:61-72 pubmed publisher |
| Lin V, Hu J, Zolekar A, Yan L, Wang Y. Urine Sample-Derived Cerebral Organoids Suitable for Studying Neurodevelopment and Pharmacological Responses. Front Cell Dev Biol. 2020;8:304 pubmed publisher |
| Huang H, Tian X, Peng X, Huang L, Mei L, Zhan Y, et al. Antifungal itraconazole ameliorates experimental autoimmune encephalomyelitis through a novel mechanism of action. Adv Clin Exp Med. 2020;29:535-545 pubmed publisher |
| Kurppa K, Liu Y, To C, Zhang T, Fan M, Vajdi A, et al. Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway. Cancer Cell. 2020;37:104-122.e12 pubmed publisher |
| Du J, Gao R, Wang Y, Nguyen T, Yang F, Shi Y, et al. MicroRNA-26a/b have protective roles in oral lichen planus. Cell Death Dis. 2020;11:15 pubmed publisher |
| Langley M, Yoon H, Kim H, Choi C, Simon W, Kleppe L, et al. High fat diet consumption results in mitochondrial dysfunction, oxidative stress, and oligodendrocyte loss in the central nervous system. Biochim Biophys Acta Mol Basis Dis. 2020;1866:165630 pubmed publisher |
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| Attia G, Elmansy R, Elsaed W. Neuroprotective effect of nilotinib on pentylenetetrazol-induced epilepsy in adult rat hippocampus: involvement of oxidative stress, autophagy, inflammation, and apoptosis. Folia Neuropathol. 2019;57:146-160 pubmed publisher |
| ElKhoely A. Diallyl sulfide ameliorates carbon tetrachloride-induced hepatotoxicity in rats via suppressing stress-activated MAPK signaling pathways. J Biochem Mol Toxicol. 2019;33:e22307 pubmed publisher |
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