This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Bax Monoclonal Antibody (6A7), Biotin
catalog :
MA5-14000
quantity :
500µL
price :
US 399.00
clonality :
monoclonal
host :
mouse
conjugate :
biotin
clone name :
6A7
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
citations: 18
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:100; fig 6
Jiang C, Fang X, Jiang Y, Shen F, Hu Z, Li X, et al. TNF-α induces vascular endothelial cells apoptosis through overexpressing pregnancy induced noncoding RNA in Kawasaki disease model. Int J Biochem Cell Biol. 2016;72:118-124 pubmed publisher
  • western blot; rat
Xu H, Zhu G, Tian Y. Protective effects of trimetazidine on bone marrow mesenchymal stem cells viability in an ex vivo model of hypoxia and in vivo model of locally myocardial ischemia. J Huazhong Univ Sci Technolog Med Sci. 2012;32:36-41 pubmed publisher
  • western blot; rat; 1:1500
Xinxing W, Hong F, Rui Z, Yun Z, Jingbo G, Lingjia Q. Phosphorylated nerve growth factor-induced clone B (NGFI-B) translocates from the nucleus to mitochondria of stressed rat cardiomyocytes and induces apoptosis. Stress. 2012;15:545-53 pubmed publisher
  • western blot; rat; 1:1000
Baquedano E, García Cáceres C, Diz Chaves Y, Lagunas N, Calmarza Font I, Azcoitia I, et al. Prenatal stress induces long-term effects in cell turnover in the hippocampus-hypothalamus-pituitary axis in adult male rats. PLoS ONE. 2011;6:e27549 pubmed publisher
  • immunocytochemistry; human; 1.6 ug/ml
Kim B, Hong S. Sequential caspase-2 and caspase-8 activation is essential for saikosaponin a-induced apoptosis of human colon carcinoma cell lines. Apoptosis. 2011;16:184-97 pubmed publisher
  • western blot; human; 1.33 ug/ml
Kim B, Maeng K, Lee K, Hong S. Combined treatment with the Cox-2 inhibitor niflumic acid and PPAR? ligand ciglitazone induces ER stress/caspase-8-mediated apoptosis in human lung cancer cells. Cancer Lett. 2011;300:134-44 pubmed publisher
  • western blot; human
Choi B, Lee C. Cell cycle arrest and cytochrome c-mediated apoptotic induction by MCS-5A is associated with up-regulation of p16(INK4a) in HL-60 cells. Bioorg Med Chem Lett. 2010;20:3880-4 pubmed publisher
  • immunohistochemistry; mouse
Perumalsamy L, Nagala M, Sarin A. Notch-activated signaling cascade interacts with mitochondrial remodeling proteins to regulate cell survival. Proc Natl Acad Sci U S A. 2010;107:6882-7 pubmed publisher
  • immunohistochemistry; rat; 1:100
Giris M, Erbil Y, Depboylu B, Mete O, Turkoglu U, Abbasoglu S, et al. Heme oxygenase-1 prevents hyperthyroidism induced hepatic damage via an antioxidant and antiapoptotic pathway. J Surg Res. 2010;164:266-75 pubmed publisher
  • immunocytochemistry; rat; 1:500
  • western blot; rat; 1:1000
Delgado Rubín A, Chowen J, Argente J, Frago L. Growth hormone-releasing peptide 6 protection of hypothalamic neurons from glutamate excitotoxicity is caspase independent and not mediated by insulin-like growth factor I. Eur J Neurosci. 2009;29:2115-24 pubmed publisher
  • immunoprecipitation; human
Kim B, Choi Y, Han Y, Yun Y, Hong S. N,N-dimethyl phytosphingosine induces caspase-8-dependent cytochrome c release and apoptosis through ROS generation in human leukemia cells. Toxicol Appl Pharmacol. 2009;239:87-97 pubmed publisher
  • immunohistochemistry; rat; 1:500
  • western blot; rat; 1:5000
García Cáceres C, Lechuga Sancho A, Argente J, Frago L, Chowen J. Death of hypothalamic astrocytes in poorly controlled diabetic rats is associated with nuclear translocation of apoptosis inducing factor. J Neuroendocrinol. 2008;20:1348-60 pubmed publisher
  • western blot; human; 1.6 ug/ml
Kim B, Chung H. Desferrioxamine (DFX) induces apoptosis through the p38-caspase8-Bid-Bax pathway in PHA-stimulated human lymphocytes. Toxicol Appl Pharmacol. 2008;228:24-31 pubmed publisher
  • immunohistochemistry; rat
  • western blot; rat
Chen X, Chen Y, Bi Y, Fu N, Shan C, Wang S, et al. Preventive cardioprotection of erythropoietin against doxorubicin-induced cardiomyopathy. Cardiovasc Drugs Ther. 2007;21:367-74 pubmed
  • immunocytochemistry; human
Parikh N, Koshy C, Dhayabaran V, Perumalsamy L, Sowdhamini R, Sarin A. The N-terminus and alpha-5, alpha-6 helices of the pro-apoptotic protein Bax, modulate functional interactions with the anti-apoptotic protein Bcl-xL. BMC Cell Biol. 2007;8:16 pubmed
  • western blot; mouse; 1:1000
Ray S, Chatterjee A. Influence of glutathione on the induction of chromosome aberrations, delay in cell cycle kinetics and cell cycle regulator proteins in irradiated mouse bone marrow cells. Int J Radiat Biol. 2007;83:347-54 pubmed
  • immunocytochemistry; rat; 1:100
Chai Y, Niu L, Sun X, Ding J, Hu G. Iptakalim protects PC12 cell against H2O2-induced oxidative injury via opening mitochondrial ATP-sensitive potassium channel. Biochem Biophys Res Commun. 2006;350:307-14 pubmed
Jordà E, Verdaguer E, Jimenez A, Canudas A, Rimbau V, Camps P, et al. (+/-)-huprine Y, (-)-huperzine A and tacrine do not show neuroprotective properties in an apoptotic model of neuronal cytoskeletal alteration. J Alzheimers Dis. 2004;6:577-83; discussion 673-81 pubmed
product information
Product Type :
Antibody
Product Name :
Bax Monoclonal Antibody (6A7), Biotin
Catalog # :
MA5-14000
Quantity :
500µL
Price :
US 399.00
Clonality :
Monoclonal
Purity :
Protein G
Host :
Mouse
Reactivity :
Human, Mouse, Rat
Applications :
Flow Cytometry: 0.5 ug/test, Immunocytochemistry: 1:10-1:100, Immunofluorescence: 1:10-1:100, Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:10-1:100
Species :
Human, Mouse, Rat
Clone :
6A7
Isotype :
IgG1
Storage :
4° C
Description :
Bcl-2, Bax, and Bcl-X are members of a family of proteins that regulate apoptosis. In contrast to Bcl-2alpha and Bcl-XL, overexpression of bax protein accelerates the programmed cell death (apoptosis).
Immunogen :
A Synthetic peptide, aa 12-24 (Cys-GPTSSEQIMKTGA), of human Bax protein. This amino acid sequence is shared by human, mouse and rat bax protein.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.5 ug/test, Immunocytochemistry: 1:10-1:100, Immunofluorescence: 1:10-1:100, Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:10-1:100
Aliases :
apoptosis regulator BAX, bcl-2-like protein 4, bcl2-L-4
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
www.thermofisher.com
800-678-5599
headquarters: USA