SFTPB Precursor Monoclonal Antibody (SPB01 (1-2-A5-9)) | Invitrogen MA5-13975 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

SFTPB Precursor Monoclonal Antibody (SPB01 (1-2-A5-9))

catalog :

MA5-13975

quantity :

500 uL

price :

US 480.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

SPB01 (1-2-A5-9)

reactivity :

human, rat

application :

immunohistochemistry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human; 1:100	Kim H, Jang S, Chung D, Yoo S, Sun P, Jin Y, et al. A comprehensive comparative analysis of the histomorphological features of ALK-rearranged lung adenocarcinoma based on driver oncogene mutations: frequent expression of epithelial-mesenchymal transition markers than other genotype. PLoS ONE. 2013;8:e76999 pubmed publisher
immunohistochemistry; human; 1:100	Aiad H, El Farargy S, Soliman M, El Wahed Gaber M, El Aziz Othman S. Immunohistochemical staining of surfactant proteins A and B in skin of psoriatic patients before and after narrow-band UVB phototherapy. Am J Clin Dermatol. 2012;13:341-8 pubmed publisher
immunohistochemistry; human	Peca D, Petrini S, Tzialla C, Boldrini R, Morini F, Stronati M, et al. Altered surfactant homeostasis and recurrent respiratory failure secondary to TTF-1 nuclear targeting defect. Respir Res. 2011;12:115 pubmed publisher
immunohistochemistry; human; 1:25	Zhang P, Gao H, Pasha T, Litzky L, LiVolsi V. TTF-1 expression in ovarian and uterine epithelial neoplasia and its potential significance, an immunohistochemical assessment with multiple monoclonal antibodies and different secondary detection systems. Int J Gynecol Pathol. 2009;28:10-8 pubmed publisher
immunohistochemistry; human; 1:50	Marci V, Volante M, Cappia S, Righi L, Novello C, Scagliotti G, et al. Basaloid adenocarcinoma. A new variant of pulmonary adenocarcinoma. Virchows Arch. 2007;451:729-36 pubmed
	Yang M, Hilton M, Seaman S, Haines D, Nagashima K, Burks C, et al. Essential regulation of lung surfactant homeostasis by the orphan G protein-coupled receptor GPR116. Cell Rep. 2013;3:1457-64 pubmed publisher

product information

Product Type :

Antibody

Product Name :

SFTPB Precursor Monoclonal Antibody (SPB01 (1-2-A5-9))

Catalog # :

MA5-13975

Quantity :

500 uL

Price :

US 480.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human, Rat

Applications :

Immunohistochemistry (Paraffin): 2-4 ug/mL

Species :

Human, Rat

Clone :

SPB01 (1-2-A5-9)

Isotype :

IgG2a, kappa

Storage :

4 C

Description :

Pulmonary surfactant is a complex mixture of phospholipids and proteins that is secreted from type II cells in alveoli and reduces the surface tension at the alveolar air-liquid interface, providing alveolar stability necessary for normal ventillation. Four distinct proteins isolated from pulmonary surfactant are termed surfactant proteins A, B, C, and D. SP-A (28-36kDa) and SP-D (43kDa) are collagenous carbohydrate-binding proteins, whereas SP-B (8-9kDa) and SP-C (4kDa) are non-collagenous hydrophobic proteins. SP-B is expressed in pulmonary adenocarcinomas with acinar, papillary, bronchioloalveolar, and solid growth patterns. Squamous cell and large cell carcinomas of the lung and nonpulmonary adenocarcinomas do not express SP-B. ProSP-B is glycosylated in the Golgi apparatus and undergoes carboxy- and amino-terminal proteolysis by a cathepsin D-like protease.

Immunogen :

Recombinant pro-surfactant protein B

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 2-4 ug/mL

Aliases :

18 kDa pulmonary-surfactant protein; 6 kDa protein; PSP-B; Pulmonary surfactant-associated protein B; pulmonary surfactant-associated proteolipid SPL(Phe); SFTB3; SFTP3; SFTPB; SMDP1; SP-B; surfactant associated protein B; surfactant protein B; surfactant pulmonary-associated protein B; surfactant, pulmonary-associated protein B

more info or order :

Invitrogen product webpage