RPA70 Monoclonal Antibody (2H10) | Invitrogen MA5-13953 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

RPA70 Monoclonal Antibody (2H10)

catalog :

MA5-13953

quantity :

500 µL

price :

US 440.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2H10

reactivity :

human

application :

western blot, immunoprecipitation

citations: 6

Reference
Toledo L, Murga M, Gutierrez Martinez P, Soria R, Fernandez Capetillo O. ATR signaling can drive cells into senescence in the absence of DNA breaks. Genes Dev. 2008;22:297-302 pubmed publisher
Nakai Murakami C, Shimura M, Kinomoto M, Takizawa Y, Tokunaga K, Taguchi T, et al. HIV-1 Vpr induces ATM-dependent cellular signal with enhanced homologous recombination. Oncogene. 2007;26:477-86 pubmed
Camarda G, Siepi F, Pajalunga D, Bernardini C, Rossi R, Montecucco A, et al. A pRb-independent mechanism preserves the postmitotic state in terminally differentiated skeletal muscle cells. J Cell Biol. 2004;167:417-23 pubmed
Meetei A, Sechi S, Wallisch M, Yang D, Young M, Joenje H, et al. A multiprotein nuclear complex connects Fanconi anemia and Bloom syndrome. Mol Cell Biol. 2003;23:3417-26 pubmed
Sukhodolets K, Hickman A, Agarwal S, Sukhodolets M, Obungu V, Novotny E, et al. The 32-kilodalton subunit of replication protein A interacts with menin, the product of the MEN1 tumor suppressor gene. Mol Cell Biol. 2003;23:493-509 pubmed
Kogure T, Takasaki Y, Takeuchi K, Yamada H, Nawata M, Ikeda K, et al. Autoimmune responses to proliferating cell nuclear antigen multiprotein complexes involved in cell proliferation are strongly associated with their structure and biologic function in patients with systemic lupus erythematosus. Arthritis Rheum. 2002;46:2946-56 pubmed

product information

Product Type :

Antibody

Product Name :

RPA70 Monoclonal Antibody (2H10)

Catalog # :

MA5-13953

Quantity :

500 µL

Price :

US 440.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human

Applications :

Gel Shift: 1 mg/mL, Immunoprecipitation: 2 µg/mL, Western Blot: 1-2 µg/mL

Species :

Human

Clone :

2H10

Isotype :

IgG1, kappa

Storage :

4° C

Description :

This gene Plays an essential role in several cellular processes in DNA metabolism including replication, recombination and DNA repair. Binds and subsequently stabilizes single-stranded DNA intermediates and thus prevents complementary DNA from reannealing.

Immunogen :

Purified human RPA protein

Format :

Liquid

Applications w/Dilutions :

Gel Shift: 1 mg/mL, Immunoprecipitation: 2 µg/mL, Western Blot: 1-2 µg/mL

Aliases :

5031405K23Rik; 70kDa; AA589576; AW557552; Cb1-727; HSSB; MST075; MSTP075; REPA1; Replication factor A protein 1; replication protein A 70 kDa DNA-binding subunit; Replication protein A 70 kDa DNA-binding subunit, N-terminally processed; replication protein A1; replication protein A1, 70kDa; RF-A; RF-A protein 1; Rpa; RP-A; RP-A p70; RPA1; RPA70; Single-stranded DNA-binding protein