TGF alpha Monoclonal Antibody (MF9) | Invitrogen MA5-13907 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TGF alpha Monoclonal Antibody (MF9)

catalog :

MA5-13907

quantity :

500 µL

price :

US 436.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

MF9

reactivity :

human, mouse, rat, bovine

application :

western blot, immunohistochemistry

citations: 6

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human	Chan Y, Fenoglio Simeone K, Paraschos S, Muhammad L, Troester M, Ng Y, et al. Central precocious puberty due to hypothalamic hamartomas correlates with anatomic features but not with expression of GnRH, TGFalpha, or KISS1. Horm Res Paediatr. 2010;73:312-9 pubmed publisher
western blot; mouse; 1:50	Aguirre A, Dupree J, Mangin J, Gallo V. A functional role for EGFR signaling in myelination and remyelination. Nat Neurosci. 2007;10:990-1002 pubmed
immunohistochemistry; human; 1:200	Hays S, Fahy J. Characterizing mucous cell remodeling in cystic fibrosis: relationship to neutrophils. Am J Respir Crit Care Med. 2006;174:1018-24 pubmed
western blot; mouse	Mitchell C, Nivison M, Jackson L, Fox R, Lee D, Campbell J, et al. Heparin-binding epidermal growth factor-like growth factor links hepatocyte priming with cell cycle progression during liver regeneration. J Biol Chem. 2005;280:2562-8 pubmed
	Myers T, Brennaman L, Stevenson M, Higashiyama S, Russell W, Lee D, et al. Mitochondrial reactive oxygen species mediate GPCR-induced TACE/ADAM17-dependent transforming growth factor-alpha shedding. Mol Biol Cell. 2009;20:5236-49 pubmed publisher
	Li X, Sankrithi N, Davis F. Transforming growth factor-alpha is expressed in astrocytes of the suprachiasmatic nucleus in hamster: role of glial cells in circadian clocks. Neuroreport. 2002;13:2143-7 pubmed

product information

Product Type :

Antibody

Product Name :

TGF alpha Monoclonal Antibody (MF9)

Catalog # :

MA5-13907

Quantity :

500 µL

Price :

US 436.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Bovine, Human, Mouse, Rat

Applications :

Western Blot: 1-2 µg/mL

Species :

Bovine, Human, Mouse, Rat

Clone :

MF9

Isotype :

IgG1, kappa

Storage :

4° C

Description :

TGF-alpha is an EGF-related polypeptide growth factor that signals through the EGF receptor, and stimulates the proliferation of a wide range of epidermal and epithelial cells. It is produced by monocytes, keratinocytes, and various tumor cells. TGF-alpha induces anchorage-independence transformation in cultured cells. Human, murine and rat TGF-alpha are cross-species reactive. TGFalpha (aa 50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.

Immunogen :

A 17-amino acid synthetic peptide from the carboxyl-terminus of Rat TGFalpha

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1-2 µg/mL

Aliases :

EGF-like TGF; ETGF; I79_019067; LOC100009150; Protransforming growth factor alpha; RATTGFAA; TFGA; TGF a; TGF type 1; TGF a; TGFA; TGFAA; TGFalpha; TGF-alpha; TGFa; Transforming growth factor; Transforming growth factor alpha; transforming growth factor, alpha; transforming growth factor-alpha; wa1; wa-1; waved 1