MVP Monoclonal Antibody (1032), Biotin | Invitrogen MA5-13868 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

MVP Monoclonal Antibody (1032), Biotin

catalog :

MA5-13868

quantity :

500 uL

price :

US 484.00

clonality :

monoclonal

host :

mouse

conjugate :

biotin

clone name :

1032

reactivity :

human, rat

application :

western blot, immunohistochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 2

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human; 1:100	Henríquez Hernández L, Moreno M, Rey A, Lloret M, Lara P. MVP expression in the prediction of clinical outcome of locally advanced oral squamous cell carcinoma patients treated with radiotherapy. Radiat Oncol. 2012;7:147 pubmed publisher
	Guan J, Chen X, Zhu H, Luo S, Cao B, Ding L. Involvement of extracellular signal-regulated kinase/mitogen-activated protein kinase pathway in multidrug resistance induced by HBx in hepatoma cell line. World J Gastroenterol. 2004;10:3522-7 pubmed

product information

Product Type :

Antibody

Product Name :

MVP Monoclonal Antibody (1032), Biotin

Catalog # :

MA5-13868

Quantity :

500 uL

Price :

US 484.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human, Rat

Applications :

Flow Cytometry: Assay-dependent, Gel Shift: 1mg/mL, Immunohistochemistry (Paraffin): 1:50-1:100, Immunoprecipitation: 2 ug/mL, Western Blot: 1-2 ug/mL

Species :

Human, Rat

Clone :

1032

Isotype :

IgG1, kappa

Storage :

4 C

Description :

This gene encodes the major vault protein which is a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, perhaps via a transport process. It is widely distributed in normal tissues, and overexpressed in multidrug-resistant cancer cells. The protein overexpression is a potentially useful marker of clinical drug resistance. This gene produces two transcripts by using two alternative exon 2 sequences; however, the open reading frames are the same in both transcripts.

Immunogen :

Proteins precipitated with AER317 from the phosphocellulose column flow through of extract of human breast cancer MCF-7 cells

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: Assay-dependent, Gel Shift: 1mg/mL, Immunohistochemistry (Paraffin): 1:50-1:100, Immunoprecipitation: 2 ug/mL, Western Blot: 1-2 ug/mL

Aliases :

2310009M24Rik; LRP; Lung resistance-related protein; major vault protein; MVP; MVP1; Testicular Secretory Protein Li 30; VAULT1; vRNP

more info or order :

Invitrogen product webpage