HGF Monoclonal Antibody (4C12.1) | Invitrogen MA5-13841 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

HGF Monoclonal Antibody (4C12.1)

catalog :

MA5-13841

quantity :

500µL

price :

375.00 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

4C12.1

reactivity :

human, dogs

application :

western blot, ELISA

citations: 2

Published Application/Species/Sample/Dilution	Reference
ELISA; dogs western blot; dogs; 1:100	Arends B, Spee B, Hoffmann G, Jansen G, Slump E, Auriemma E, et al. In vitro and in vivo bioactivity of recombinant canine hepatocyte growth factor. Vet J. 2008;178:70-7 pubmed publisher
	Gjørlund M, Carlsen E, Kønig A, Dmytrieva O, Petersen A, Jacobsen J, et al. Soluble Ectodomain of Neuroligin 1 Decreases Synaptic Activity by Activating Metabotropic Glutamate Receptor 2. Front Mol Neurosci. 2017;10:116 pubmed publisher

product information

Product Type :

Antibody

Product Name :

HGF Monoclonal Antibody (4C12.1)

Catalog # :

MA5-13841

Quantity :

500µL

Price (USD) :

375.00 USD

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

Western Blot: Assay Dependent

Species :

Human

Clone :

4C12.1

Isotype :

IgG2b

Storage :

4° C

Description :

Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms.

Immunogen :

Recombinant human HGF protein

Format :

Liquid

Applications w/Dilutions :

Western Blot: Assay Dependent

Aliases :

C230052L06Rik; DFNB39; fibroblast-derived tumor cytotoxic factor; F-TCF; hepatocyte growth factor; hepatocyte growth factor (hepapoietin A; scatter factor); Hepatocyte growth factor alpha chain; Hepatocyte growth factor beta chain; Hepatopoeitin A; hepatopoeitin-A; HepatopoietinA; hepatopoietin-A; Hgf; HGF/SF; HGFB; HPTA; lung fibroblast-derived mitogen; NK1; NK2; Scatter factor; SF; SF/HGF