Cytokeratin 16 Monoclonal Antibody (LL025) | Invitrogen MA5-13730 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Cytokeratin 16 Monoclonal Antibody (LL025)

catalog :

MA5-13730

quantity :

500 µL

price :

US 416

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

LL025

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, blocking or activating experiments

citations: 17

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 1d immunohistochemistry; mouse; loading ...; fig 1g	Takahashi T, Asano Y, Sugawara K, Yamashita T, Nakamura K, Saigusa R, et al. Epithelial Fli1 deficiency drives systemic autoimmunity and fibrosis: Possible roles in scleroderma. J Exp Med. 2017;214:1129-1151 pubmed publisher
immunohistochemistry; human; loading ...; fig 2a	Tsianakas A, Brunner P, Ghoreschi K, Berger C, Loser K, RÃ¶cken M, et al. The single-chain anti-TNF-Î± antibody DLX105 induces clinical and biomarker responses upon local administration in patients with chronic plaque-type psoriasis. Exp Dermatol. 2016;25:428-33 pubmed publisher
immunohistochemistry; human; 1:100	Matsusaki M, Fujimoto K, Shirakata Y, Hirakawa S, Hashimoto K, Akashi M. Development of full-thickness human skin equivalents with blood and lymph-like capillary networks by cell coating technology. J Biomed Mater Res A. 2015;103:3386-96 pubmed publisher
immunocytochemistry; human	Moffatt Jauregui C, Robinson B, de Moya A, Brockman R, Roman A, Cash M, et al. Establishment and characterization of a telomerase immortalized human gingival epithelial cell line. J Periodontal Res. 2013;48:713-21 pubmed publisher
immunohistochemistry; human	Yang L, Hashimoto K, Tohyama M, Okazaki H, Dai X, Hanakawa Y, et al. Interactions between myofibroblast differentiation and epidermogenesis in constructing human living skin equivalents. J Dermatol Sci. 2012;65:50-7 pubmed publisher
immunohistochemistry; human	Sakamoto K, Aragaki T, Morita K, Kawachi H, Kayamori K, Nakanishi S, et al. Down-regulation of keratin 4 and keratin 13 expression in oral squamous cell carcinoma and epithelial dysplasia: a clue for histopathogenesis. Histopathology. 2011;58:531-42 pubmed publisher
immunohistochemistry; human	Garcia M, Larcher F, Hickerson R, Baselga E, Leachman S, Kaspar R, et al. Development of skin-humanized mouse models of pachyonychia congenita. J Invest Dermatol. 2011;131:1053-60 pubmed publisher
blocking or activating experiments; human	Wu C, Luan Q, Li C, Zheng Z. Effects of antikeratin 16 antibodies on the expression of Toll-like receptors 2 and 4 in keratinocytes. Clin Exp Dermatol. 2009;34:236-9 pubmed publisher
immunohistochemistry; human; 1:500	Beckstead B, Tung J, Liang K, Tavakkol Z, Usui M, Olerud J, et al. Methods to promote Notch signaling at the biomaterial interface and evaluation in a rafted organ culture model. J Biomed Mater Res A. 2009;91:436-46 pubmed publisher
immunohistochemistry; human	Aden N, Shiwen X, Aden D, Black C, Nuttall A, Denton C, et al. Proteomic analysis of scleroderma lesional skin reveals activated wound healing phenotype of epidermal cell layer. Rheumatology (Oxford). 2008;47:1754-60 pubmed publisher
blocking or activating experiments; human	Wu C, Li C, Wei L, Zheng Z. Innate immune modulation of keratinocytes by antikeratin 16 antibodies. Exp Dermatol. 2008;17:645-52 pubmed publisher
immunohistochemistry; human; 1:500	Usui M, Mansbridge J, Carter W, Fujita M, Olerud J. Keratinocyte migration, proliferation, and differentiation in chronic ulcers from patients with diabetes and normal wounds. J Histochem Cytochem. 2008;56:687-96 pubmed publisher
immunohistochemistry; human; 1:500	Usui M, Underwood R, Mansbridge J, Muffley L, Carter W, Olerud J. Morphological evidence for the role of suprabasal keratinocytes in wound reepithelialization. Wound Repair Regen. 2005;13:468-79 pubmed
	Schreurs O, Karatsaidis A, Balta M, Grung B, Hals E, Schenck K. Expression of keratins 8, 18, and 19 in epithelia of atrophic oral lichen planus. Eur J Oral Sci. 2020;128:7-17 pubmed publisher
	Scholl F, Dumesic P, Khavari P. Mek1 alters epidermal growth and differentiation. Cancer Res. 2004;64:6035-40 pubmed
	Chang Y, Liu H, Wang W, Lee D, Tsai S. A study of cytokeratin profiles in localized cutaneous amyloids. Arch Dermatol Res. 2004;296:83-8 pubmed
	Hinterhuber G, Marquardt Y, Diem E, Rappersberger K, Wolff K, Foedinger D. Organotypic keratinocyte coculture using normal human serum: an immunomorphological study at light and electron microscopic levels. Exp Dermatol. 2002;11:413-20 pubmed

product information

Product Type :

Antibody

Product Name :

Cytokeratin 16 Monoclonal Antibody (LL025)

Catalog # :

MA5-13730

Quantity :

500 µL

Price :

US 416

Clonality :

Monoclonal

Purity :

Ammonium sulfate precipitation

Host :

Mouse

Reactivity :

Human

Applications :

Immunofluorescence: Assay Dependent, Immunohistochemistry (Paraffin): 1-2 µg/mL, Western Blot: 2 µg/mL

Species :

Human

Clone :

LL025

Isotype :

IgG1

Storage :

4° C

Description :

KRT16 is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region of chromosome 17q12-q21. This keratin has been coexpressed with keratin 14 in a number of epithelial tissues, including esophagus, tongue, and hair follicles. Mutations in this gene are associated with type 1 pachyonychia congenita, non-epidermolytic palmoplantar keratoderma and unilateral palmoplantar verrucous nevus.

Immunogen :

A synthetic peptide from the C-terminus of human cytokeratin 16

Format :

Liquid

Applications w/Dilutions :

Immunofluorescence: Assay Dependent, Immunohistochemistry (Paraffin): 1-2 µg/mL, Western Blot: 2 µg/mL

Aliases :

AI324768; CK16; CK-16; cytokeratin 16; cytokeratin-16; FNEPPK; focal non-epidermolytic palmoplantar keratoderma; K16; K1CP; Ka16; keratin 16; keratin 16, type I; keratin complex 1, acidic, gene 16; keratin intermediate filament 16a; keratin intermediate filament 16b; keratin, type I cytoskeletal 16; Keratin-16; Krt1-16; KRT16; KRT16A; NEPPK; PC1; type I keratin KA16