This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Cytokeratin 10 Monoclonal Antibody (DE-K10), Biotin
catalog :
MA5-13702
quantity :
500 uL
price :
US 484.00
clonality :
monoclonal
host :
mouse
conjugate :
biotin
clone name :
DE-K10

The same clone is also sold as:
reactivity :
human, rat, dogs, cat
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
citations: 26
Reference
van Drongelen V, Danso M, Mulder A, Mieremet A, Van Smeden J, Bouwstra J, et al. Barrier properties of an N/TERT-based human skin equivalent. Tissue Eng Part A. 2014;20:3041-9 pubmed publisher
Mitchell D, Israr M, Alam S, Dinello D, Kishel J, Jia R, et al. HIV nucleoside reverse transcriptase inhibitors efavirenz and tenofovir change the growth and differentiation of primary gingival epithelium. HIV Med. 2014;15:196-202 pubmed publisher
Haisma E, Rietveld M, de Breij A, van Dissel J, El Ghalbzouri A, Nibbering P. Inflammatory and antimicrobial responses to methicillin-resistant Staphylococcus aureus in an in vitro wound infection model. PLoS ONE. 2013;8:e82800 pubmed publisher
von Neubeck C, Shankaran H, Geniza M, Kauer P, Robinson R, Chrisler W, et al. Integrated experimental and computational approach to understand the effects of heavy ion radiation on skin homeostasis. Integr Biol (Camb). 2013;5:1229-43 pubmed publisher
Pal S, Sakamoto K, Aragaki T, Akashi T, Yamaguchi A. The expression profiles of acidic epithelial keratins in ameloblastoma. Oral Surg Oral Med Oral Pathol Oral Radiol. 2013;115:523-31 pubmed publisher
Kretz M, Siprashvili Z, Chu C, Webster D, Zehnder A, Qu K, et al. Control of somatic tissue differentiation by the long non-coding RNA TINCR. Nature. 2013;493:231-5 pubmed publisher
Liao S, Hsieh P, Huang J, Hsu C, Yuan K. Aberrant keratinization of reticular oral lichen planus is related to elastolysis. Oral Surg Oral Med Oral Pathol Oral Radiol. 2012;113:808-16 pubmed publisher
Yang F, Waters K, Webb Robertson B, Sowa M, von Neubeck C, Aldrich J, et al. Quantitative phosphoproteomics identifies filaggrin and other targets of ionizing radiation in a human skin model. Exp Dermatol. 2012;21:352-7 pubmed publisher
Mitchell D, Israr M, Alam S, Kishel J, Dinello D, Meyers C. Effect of the HIV nucleoside reverse transcriptase inhibitor zidovudine on the growth and differentiation of primary gingival epithelium. HIV Med. 2012;13:276-90 pubmed publisher
Alexaki V, Pelekanou V, Notas G, Venihaki M, Kampa M, Dessirier V, et al. B-cell maturation antigen (BCMA) activation exerts specific proinflammatory effects in normal human keratinocytes and is preferentially expressed in inflammatory skin pathologies. Endocrinology. 2012;153:739-49 pubmed publisher
Li B, Li J, Devlin B, Markert M. Thymic microenvironment reconstitution after postnatal human thymus transplantation. Clin Immunol. 2011;140:244-59 pubmed publisher
Sakamoto K, Aragaki T, Morita K, Kawachi H, Kayamori K, Nakanishi S, et al. Down-regulation of keratin 4 and keratin 13 expression in oral squamous cell carcinoma and epithelial dysplasia: a clue for histopathogenesis. Histopathology. 2011;58:531-42 pubmed publisher
Obarzanek Fojt M, Favre B, Kypriotou M, Ryser S, Huber M, Hohl D. Homeodomain-only protein HOP is a novel modulator of late differentiation in keratinocytes. Eur J Cell Biol. 2011;90:279-90 pubmed publisher
Obarzanek Fojt M, Favre B, Huber M, Ryser S, Moodycliffe A, Wipff P, et al. Induction of p38, tumour necrosis factor-? and RANTES by mechanical stretching of keratinocytes expressing mutant keratin 10R156H. Br J Dermatol. 2011;164:125-34 pubmed publisher
Israr M, Mitchell D, Alam S, Dinello D, Kishel J, Meyers C. The HIV protease inhibitor lopinavir/ritonavir (Kaletra) alters the growth, differentiation and proliferation of primary gingival epithelium. HIV Med. 2011;12:145-56 pubmed publisher
Metallo C, Azarin S, Moses L, Ji L, de Pablo J, Palecek S. Human embryonic stem cell-derived keratinocytes exhibit an epidermal transcription program and undergo epithelial morphogenesis in engineered tissue constructs. Tissue Eng Part A. 2010;16:213-23 pubmed publisher
Charest J, Jennings J, King W, Kowalczyk A, Garcia A. Cadherin-mediated cell-cell contact regulates keratinocyte differentiation. J Invest Dermatol. 2009;129:564-72 pubmed publisher
Markert M, Li J, Devlin B, Hoehner J, Rice H, Skinner M, et al. Use of allograft biopsies to assess thymopoiesis after thymus transplantation. J Immunol. 2008;180:6354-64 pubmed
Lalli A, Tilakaratne W, Ariyawardana A, Fitchett C, Leigh I, Hagi Pavli E, et al. An altered keratinocyte phenotype in oral submucous fibrosis: correlation of keratin K17 expression with disease severity. J Oral Pathol Med. 2008;37:211-20 pubmed publisher
Fukui D, Bando G, Ishikawa Y, Kadota K. Adenosquamous carcinoma with cilium formation, mucin production and keratinization in the nasal cavity of a red fox (Vulpes vulpes schrencki). J Comp Pathol. 2007;137:142-5 pubmed
Aho S. Plakin proteins are coordinately cleaved during apoptosis but preferentially through the action of different caspases. Exp Dermatol. 2004;13:700-7 pubmed
Chang Y, Liu H, Wang W, Lee D, Tsai S. A study of cytokeratin profiles in localized cutaneous amyloids. Arch Dermatol Res. 2004;296:83-8 pubmed
Apaydin R, Gurbuz Y, Bayramgurler D, Muezzinoglu B, Bilen N. Cytokeratin expression in lichen amyloidosus and macular amyloidosis. J Eur Acad Dermatol Venereol. 2004;18:305-9 pubmed
Hale L, Buckley R, Puck J, Patel D. Abnormal development of thymic dendritic and epithelial cells in human X-linked severe combined immunodeficiency. Clin Immunol. 2004;110:63-70 pubmed
Hale L, Markert M. Corticosteroids regulate epithelial cell differentiation and Hassall body formation in the human thymus. J Immunol. 2004;172:617-24 pubmed
Sanchez Carbayo M, Socci N, Charytonowicz E, Lu M, Prystowsky M, Childs G, et al. Molecular profiling of bladder cancer using cDNA microarrays: defining histogenesis and biological phenotypes. Cancer Res. 2002;62:6973-80 pubmed
product information
Product Type :
Antibody
Product Name :
Cytokeratin 10 Monoclonal Antibody (DE-K10), Biotin
Catalog # :
MA5-13702
Quantity :
500 uL
Price :
US 484.00
Clonality :
Monoclonal
Purity :
Protein G
Host :
Mouse
Reactivity :
Canine, Feline, Human, Rat
Applications :
Immunohistochemistry (Paraffin): 0.5-1.0 ug/mL, Western Blot: 1-2 ug/mL
Species :
Canine, Feline, Human, Rat
Clone :
DE-K10
Isotype :
IgG1
Storage :
4 C
Description :
Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinizing tissue (i.e., skin) and non-keratinizing cells (i.e. mesothelial cells). Although not a traditional marker for endothelial cells, cytokeratins have also been found in some microvascular endothelial cells. At least 20 different cytokeratins (CK) in the molecular range of 40-70 kDa and isoelectric points of 5-8. 5 can be identified using two dimensional gel electrophoresis. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells. Monoclonal antibodies to cytokeratin proteins can be useful markers for tumor identification and classification.
Immunogen :
Cytoskeletal preparation extracted from human ectocervical epithelium
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry (Paraffin): 0.5-1.0 ug/mL, Western Blot: 1-2 ug/mL
Aliases :
56 kDa cytokeratin; BCIE; BIE; CK10; CK-10; CK-17; cytokeratin 10; cytokeratin-10; cytokeratin-17; D130054E02Rik; EHK; epidermal keratin 10; epithelial keratin 10; intermediate filament protein; K10; K1C1; Ka10; Ker10; keratin 10; keratin 10 (epidermolytic hyperkeratosis; keratosis palmaris et plantaris); keratin 10, type I; keratin complex 1, acidic, gene 10; keratin, type I cytoskeletal 10; Keratin, type I cytoskeletal 59 kDa; keratin-10; keratin-17; KPP; Krt-1.10; KRT10; krt10 {ECO:0000250; Krt1-10; suprabasal cytokeratin 10; type I keratin KA10; UniProtKB:P13645}
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA