Adenovirus Type 5 Monoclonal Antibody (M58) | Invitrogen MA5-13643 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Adenovirus Type 5 Monoclonal Antibody (M58)

catalog :

MA5-13643

quantity :

500 µL

price :

US 395.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

M58

reactivity :

Adenoviridae, Human mastadenovirus C, human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

Invitrogen product webpage

citations: 14

Published Application/Species/Sample/Dilution	Reference
western blot; human	He X, Wang Z, Wei H, Zhou Q, Wang D, Tian J, et al. Construction of urothelium-specific recombinant adenovirus and its inhibition in bladder cancer cell. Urol Int. 2009;82:209-13 pubmed publisher
western blot; Adenoviridae	Ulasov I, Sonabend A, Nandi S, Khramtsov A, Han Y, Lesniak M. Combination of adenoviral virotherapy and temozolomide chemotherapy eradicates malignant glioma through autophagic and apoptotic cell death in vivo. Br J Cancer. 2009;100:1154-64 pubmed publisher
immunocytochemistry; Adenoviridae western blot; Adenoviridae	Ulasov I, Tyler M, Zhu Z, Han Y, He T, Lesniak M. Oncolytic adenoviral vectors which employ the survivin promoter induce glioma oncolysis via a process of beclin-dependent autophagy. Int J Oncol. 2009;34:729-42 pubmed
immunohistochemistry; Adenoviridae	Sonabend A, Ulasov I, Han Y, Rolle C, Nandi S, Cao D, et al. Biodistribution of an oncolytic adenovirus after intracranial injection in permissive animals: a comparative study of Syrian hamsters and cotton rats. Cancer Gene Ther. 2009;16:362-72 pubmed publisher
western blot; Adenoviridae	Ulasov I, Tyler M, Rivera A, Nettlebeck D, Douglas J, Lesniak M. Evaluation of E1A double mutant oncolytic adenovectors in anti-glioma gene therapy. J Med Virol. 2008;80:1595-603 pubmed publisher
western blot; mouse	Cheng K, Grisendi S, Clohessy J, Majid S, Bernardi R, Sportoletti P, et al. The leukemia-associated cytoplasmic nucleophosmin mutant is an oncogene with paradoxical functions: Arf inactivation and induction of cellular senescence. Oncogene. 2007;26:7391-400 pubmed
western blot; Adenoviridae	Li Y, Idamakanti N, Arroyo T, Thorne S, Reid T, Nichols S, et al. Dual promoter-controlled oncolytic adenovirus CG5757 has strong tumor selectivity and significant antitumor efficacy in preclinical models. Clin Cancer Res. 2005;11:8845-55 pubmed
	Saha B, Parks R. Identification of human adenovirus replication inhibitors from a library of small molecules targeting cellular epigenetic regulators. Virology. 2021;555:102-110 pubmed publisher
	Jennings M, Parks R. Antiviral Effects of Curcumin on Adenovirus Replication. Microorganisms. 2020;8: pubmed publisher
	Jiang H, Leung C, Tahan S, Wang D. Entry by multiple picornaviruses is dependent on a pathway that includes TNK2, WASL, and NCK1. elife. 2019;8: pubmed publisher
	Saha B, Parks R. Histone Deacetylase Inhibitor Suberoylanilide Hydroxamic Acid Suppresses Human Adenovirus Gene Expression and Replication. J Virol. 2019;93: pubmed publisher
	Li X, Wang P, Li H, Du X, Liu M, Huang Q, et al. The Efficacy of Oncolytic Adenovirus Is Mediated by T-cell Responses against Virus and Tumor in Syrian Hamster Model. Clin Cancer Res. 2017;23:239-249 pubmed publisher
	Lu W, Zheng S, Li X, Huang J, Zheng X, Li Z. Intra-tumor injection of H101, a recombinant adenovirus, in combination with chemotherapy in patients with advanced cancers: a pilot phase II clinical trial. World J Gastroenterol. 2004;10:3634-8 pubmed
	Hubberstey A, Pavliv M, Parks R. Cancer therapy utilizing an adenoviral vector expressing only E1A. Cancer Gene Ther. 2002;9:321-9 pubmed

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product information

Product Type :

Antibody

Product Name :

Adenovirus Type 5 Monoclonal Antibody (M58)

Catalog # :

MA5-13643

Quantity :

500 µL

Price :

US 395.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Virus

Applications :

Immunohistochemistry: 2-4 µg/mL, Immunoprecipitation: 2 µg/mL, Western Blot: 0.5-1.0 µg/mL

Species :

Virus

Clone :

M58

Isotype :

IgG2a, kappa

Storage :

4° C

Description :

Adenoviruses are DNA viruses generally widespread in nature that are frequently the cause of acute upper respiratory tract infections (i.e. common colds). 49 human adenovirus serotypes have been discovered and divided into six subgroups, A to E, based on observation. They are an important cause of respiratory illness, conjunctivitis, gastroenteritis, and have more recently been recognized as a potential cause of sexually transmitted diseases. Several types have oncogenic potential though most cause self-limiting febrile illnesses characterized by inflammation of conjunctivae and the respiratory tract. The virus can be isolated from the majority of tonsils/adenoids surgically removed, indicating latent infections. It is not known how long the virus can persist in the body, or whether it is capable of reactivation after long periods. In patients experiencing immunosuppression (e.g. AIDS) it can be reactivated, causing disease. Adenovirus vectors, particularly those based on Ad5, have shown great promise for the development of gene therapy protocols and have been used for clinical purpose.

Immunogen :

Adenovirus

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry: 2-4 µg/mL, Immunoprecipitation: 2 µg/mL, Western Blot: 0.5-1.0 µg/mL

Aliases :

Adeno Virus; Adeno Virus 5; AdV; AdV-5; HADV; HADV-5

more info or order :

Invitrogen product webpage