TIMP2 Monoclonal Antibody (T2-101) | Invitrogen MA5-13603 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TIMP2 Monoclonal Antibody (T2-101)

catalog :

MA5-13603

quantity :

500 µL

price :

US 496.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

T2-101

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunoprecipitation, other

more info or order :

Invitrogen product webpage

citations: 5

Published Application/Species/Sample/Dilution	Reference
other; human; loading ...; fig s1	Shah F, Stepan A, O Mahony A, Velichko S, Folias A, Houle C, et al. Mechanisms of Skin Toxicity Associated with Metabotropic Glutamate Receptor 5 Negative Allosteric Modulators. Cell Chem Biol. 2017;24:858-869.e5 pubmed publisher
western blot; human	Allam E, Zhang W, Al Shibani N, Sun J, Labban N, Song F, et al. Effects of cigarette smoke condensate on oral squamous cell carcinoma cells. Arch Oral Biol. 2011;56:1154-61 pubmed publisher
western blot; human; 5 ug/ml	Zhang W, Song F, Windsor L. Cigarette smoke condensate affects the collagen-degrading ability of human gingival fibroblasts. J Periodontal Res. 2009;44:704-13 pubmed publisher
immunohistochemistry; rat western blot; rat; 1:2000	Gantus M, Nasciutti L, Cruz C, Persechini P, Martinez A. Modulation of extracellular matrix components by metalloproteinases and their tissue inhibitors during degeneration and regeneration of rat sural nerve. Brain Res. 2006;1122:36-46 pubmed
	Giusti I, Di Francesco M, D Ascenzo S, Palmerini M, Macchiarelli G, Carta G, et al. Ovarian cancer-derived extracellular vesicles affect normal human fibroblast behavior. Cancer Biol Ther. 2018;19:722-734 pubmed publisher

image

image 1 :

product information

Product Type :

Antibody

Product Name :

TIMP2 Monoclonal Antibody (T2-101)

Catalog # :

MA5-13603

Quantity :

500 µL

Price :

US 496.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human, Mouse

Applications :

Immunoprecipitation: 2 µg/mg protein lysate, Western Blot: 1-2 µg/mL

Species :

Human, Mouse

Clone :

T2-101

Isotype :

IgG1

Storage :

4° C

Description :

TIMP-1 and TIMP-2 are inhibitory enzymes of matrix metalloproteinase family, and are thought to be of great importance in the maintenance of connective tissue integrity. TIMP-2 shows the highest binding affinity to both the latent (pro) and active forms of 72 kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92 kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.

Immunogen :

Native human pro-MMP-2/TIMP-2 complex purified from A2058 culture medium followed by purified human rTIMP-2

Format :

Liquid

Applications w/Dilutions :

Immunoprecipitation: 2 µg/mg protein lysate, Western Blot: 1-2 µg/mL

Aliases :

Collagenase inhibitor; CSC-21K; D11Bwg1104e; DDC8; etID32613.12; fa96h09; Metalloproteinase inhibitor 2; metalloproteinase inhibitor 2a; metalloproteinase inhibitor precursor; metalloproteinase inhibitor TIMP-2; metalloproteinase-2; similar to metalloproteinase inhibitor; testicular secretory protein Li 57; TIMP 2; TIMP metallopeptidase inhibitor 2; TIMP metallopeptidase inhibitor 2a; TIMP2; Timp-2; TIMP-2 protein; timp2a; tissue inhibitor of matrix metalloproteinase-2; tissue inhibitor of metalloproteinase 2; tissue inhibitor of metalloproteinase 2 precursor; tissue inhibitor of metalloproteinase 2a; tissue inhibitor of metalloproteinase-2; tissue inhibitor of metalloproteinase-2 precursor; tissue inhibitor of metalloproteinases 2; tissue inhibitor of mettaloproteinase 2; wu:fa96h09; zgc:136726

more info or order :

Invitrogen product webpage