MFGE8 (Lactadherin) Monoclonal Antibody (EDM45) | Invitrogen MA5-13556 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

MFGE8 (Lactadherin) Monoclonal Antibody (EDM45)

catalog :

MA5-13556

quantity :

500 µL

price :

US 436.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

EDM45

reactivity :

human

application :

western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 2

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:1000	Okuyama T, Kurata S, Tomimori Y, Fukunishi N, Sato S, Osada M, et al. p63(TP63) elicits strong trans-activation of the MFG-E8/lactadherin/BA46 gene through interactions between the TA and DeltaN isoforms. Oncogene. 2008;27:308-17 pubmed
	Yamazaki M, Maruyama S, AbÃ© T, Essa A, Babkair H, Cheng J, et al. MFG-E8 expression for progression of oral squamous cell carcinoma and for self-clearance of apoptotic cells. Lab Invest. 2014;94:1260-72 pubmed publisher

product information

Product Type :

Antibody

Product Name :

MFGE8 (Lactadherin) Monoclonal Antibody (EDM45)

Catalog # :

MA5-13556

Quantity :

500 µL

Price :

US 436.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human

Applications :

Immunohistochemistry (Paraffin): 1-2 µg/mL, Immunoprecipitation: 2 µg/mL, Western Blot: 0.5-1.0 µg/mL

Species :

Human

Clone :

EDM45

Isotype :

IgG1, kappa

Storage :

4° C

Description :

This gene encodes a preproprotein that is proteolytically processed to form multiple protein products. The major encoded protein product, lactadherin, is a membrane glycoprotein that promotes phagocytosis of apoptotic cells. This protein has also been implicated in wound healing, autoimmune disease, and cancer. Lactadherin can be further processed to form a smaller cleavage product, medin, which comprises the major protein component of aortic medial amyloid (AMA). Alternative splicing results in multiple transcript variants.

Immunogen :

Delipidated human milk fat globule membrane preparation

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1-2 µg/mL, Immunoprecipitation: 2 µg/mL, Western Blot: 0.5-1.0 µg/mL

Aliases :

AA408458; AGS; AI325141; BA46; breast epithelial antigen BA46; EDIL1; EGF/factor VIII; HMFG; hP47; HsT19888; lactadherin; Lactadherin short form; Medin; Mfge8; MFG-E8; MFGM; MFGME8; MFGMP-E8; milk fat globule glycoprotein; milk fat globule membrane; milk fat globule membrane protein; Milk fat globule-EGF factor 8; milk fat globule-EGF factor 8 protein; MP47; O-acetyl disialoganglioside synthase; O-acetyl GD3 ganglioside synthase; O-acetyltransferase milk fat globule membrane protein; O-acetyltransferase Milk fat glolbule membrane protein; OAcGD3S; P47; SED1; SPAG10; sperm associated antigen 10; sperm surface protein hP47; sperm surface protein SP47

more info or order :

Invitrogen product webpage