product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD155 Monoclonal Antibody (D171)
catalog :
MA5-13493
quantity :
500 µL
price :
US 410.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
D171
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, blocking or activating experiments
more info or order :
citations: 12
Published Application/Species/Sample/DilutionReference
  • ELISA; human; 0.2 ug/ml; loading ...; fig 1a
Iguchi Manaka A, Okumura G, Ichioka E, Kiyomatsu H, Ikeda T, Bando H, et al. High expression of soluble CD155 in estrogen receptor-negative breast cancer. Breast Cancer. 2020;27:92-99 pubmed publisher
  • blocking or activating experiments; human; loading ...; fig 3a, 3b, 3c, 5a
Stamm H, Klingler F, Grossjohann E, Muschhammer J, Vettorazzi E, Heuser M, et al. Immune checkpoints PVR and PVRL2 are prognostic markers in AML and their blockade represents a new therapeutic option. Oncogene. 2018;37:5269-5280 pubmed publisher
  • immunocytochemistry; human
Enloe B, Jay D. Inhibition of Necl-5 (CD155/PVR) reduces glioblastoma dispersal and decreases MMP-2 expression and activity. J Neurooncol. 2011;102:225-35 pubmed publisher
  • immunohistochemistry; human
Verhoeven D, de Hooge A, Mooiman E, Santos S, ten Dam M, Gelderblom H, et al. NK cells recognize and lyse Ewing sarcoma cells through NKG2D and DNAM-1 receptor dependent pathways. Mol Immunol. 2008;45:3917-25 pubmed publisher
  • immunocytochemistry; rat
Sloan K, Stewart J, Treloar A, Matthews R, Jay D. CD155/PVR enhances glioma cell dispersal by regulating adhesion signaling and focal adhesion dynamics. Cancer Res. 2005;65:10930-7 pubmed
Tobys D, Kowalski L, Cziudaj E, M xfc ller S, Zentis P, Pach E, et al. Inhibition of clathrin-mediated endocytosis by knockdown of AP-2 leads to alterations in the plasma membrane proteome. Traffic. 2021;22:6-22 pubmed publisher
Zitti B, Molfetta R, Fionda C, Quatrini L, Stabile H, Lecce M, et al. Innate immune activating ligand SUMOylation affects tumor cell recognition by NK cells. Sci Rep. 2017;7:10445 pubmed publisher
Sloan K, Eustace B, Stewart J, Zehetmeier C, Torella C, Simeone M, et al. CD155/PVR plays a key role in cell motility during tumor cell invasion and migration. BMC Cancer. 2004;4:73 pubmed
Ohka S, Matsuda N, Tohyama K, Oda T, Morikawa M, Kuge S, et al. Receptor (CD155)-dependent endocytosis of poliovirus and retrograde axonal transport of the endosome. J Virol. 2004;78:7186-98 pubmed
Reymond N, Imbert A, Devilard E, Fabre S, Chabannon C, Xerri L, et al. DNAM-1 and PVR regulate monocyte migration through endothelial junctions. J Exp Med. 2004;199:1331-41 pubmed
Baury B, Masson D, McDermott B, Jarry A, Blottiere H, Blanchardie P, et al. Identification of secreted CD155 isoforms. Biochem Biophys Res Commun. 2003;309:175-82 pubmed
Masson D, Jarry A, Baury B, Blanchardie P, Laboisse C, Lustenberger P, et al. Overexpression of the CD155 gene in human colorectal carcinoma. Gut. 2001;49:236-40 pubmed
product information
Product Type :
Antibody
Product Name :
CD155 Monoclonal Antibody (D171)
Catalog # :
MA5-13493
Quantity :
500 µL
Price :
US 410.00
Clonality :
Monoclonal
Purity :
Protein G
Host :
Mouse
Reactivity :
Human, Mouse, Non-human primate
Applications :
Flow Cytometry: 2 µg/test, Immunocytochemistry: 1:10-1:100, Western Blot: 1:10-1:100
Species :
Human, Mouse, Non-human primate
Clone :
D171
Isotype :
IgG1
Storage :
4° C
Description :
The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen :
HeLa cells
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 2 µg/test, Immunocytochemistry: 1:10-1:100, Western Blot: 1:10-1:100
Aliases :
3830421F03Rik; AI325026; AI987993; CD112; CD155; D7Ertd458e; FLJ25946; herpes virus entry mediator B; Herpesvirus entry mediator B; hveB; HVED; mE4; mHveB; Mph; murine herpes virus entry protein B; murine herpesvirus entry protein B; NECL5; necl-5; Nectin cell adhesion molecule 2; Nectin2; Nectin-2; nectin-like 5; nectin-like protein 5; Poliovirus receptor; poliovirus receptor homolog; poliovirus receptor-related 2; poliovirus receptor-related protein 2; poliovirus sensitivity; PVR; Pvrl2; PVS; sCD112; soluble CD112; Taa1; TAGE4; tumor-associated antigen 1; tumor-associated glycoprotein pE4
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA