ACTH Monoclonal Antibody (AH26) | Invitrogen MA5-13455 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

ACTH Monoclonal Antibody (AH26)

catalog :

MA5-13455

quantity :

500 µL

price :

US 446.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

AH26

reactivity :

human

application :

immunohistochemistry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 5

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human; 1:800	Rasul F, Jaunmuktane Z, Khan A, Phadke R, Powell M. Plurihormonal pituitary adenoma with concomitant adrenocorticotropic hormone (ACTH) and growth hormone (GH) secretion: a report of two cases and review of the literature. Acta Neurochir (Wien). 2014;156:141-6 pubmed publisher
immunohistochemistry; human	Yıldırım A, Divanlioglu D, Nacar O, Dursun E, Sahinoglu M, Unal T, et al. Incidence, hormonal distribution and postoperative follow up of atypical pituitary adenomas. Turk Neurosurg. 2013;23:226-31 pubmed publisher
immunohistochemistry; human	Rychly B, Kazakov D, Danis D, Szep Z, Michal M. Primary adenomyoepithelioma of the sellar region: a case report. Am J Surg Pathol. 2010;34:1550-4 pubmed publisher
immunohistochemistry; human	Ekici A, Eren B, Turkmen N, Comunoglu N, Fedakar R. Clusterin expression in non-neoplastic adenohypophyses and pituitary adenomas: cytoplasmic clusterin localization in adenohypophysis is related to aging. Endocr Pathol. 2008;19:47-53 pubmed publisher
	Peculis R, Mandrika I, Petrovska R, Dortane R, Megnis K, Nazarovs J, et al. Pituispheres Contain Genetic Variants Characteristic to Pituitary Adenoma Tumor Tissue. Front Endocrinol (Lausanne). 2020;11:313 pubmed publisher

image

image 1 :

Formalin-fixed, paraffin-embedded human pituitary gland stained with ACTH antibody using peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of anterior pituitary cells.

product information

Product Type :

Antibody

Product Name :

ACTH Monoclonal Antibody (AH26)

Catalog # :

MA5-13455

Quantity :

500 µL

Price :

US 446.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human

Applications :

Immunohistochemistry (Paraffin): 0.2-0.4 µg/mL

Species :

Human

Clone :

AH26

Isotype :

IgG1

Storage :

4° C

Description :

ATCH (adrenocorticotropic hormone) is a hormone which plays a major role in stimulating the adrenal cortex. It is formed through cleavage of the polypeptide precursor proopiomelanocortin (POMC), which also results in several other cleavage products including MSH, ACTH, and beta endorphin. ATCH is secreted from the anterior pituitary in response to the corticotropin-releasing hormone from the hypothalamus. It stimulates the secretion of glucocorticoids like cortisol, but has little control over the stimulation of mineralocorticoids like aldosterone, which is another major hormone of the adrenal cortex.

Immunogen :

A synthetic peptide corresponding to aa 1-24 from the N-terminal of human ACTH

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 0.2-0.4 µg/mL

Aliases :

ACTH; adrenal corticotropic hormone; adrenocorticotropic hormone; adrenocorticotropin; alpha-melanocyte stimulating hormone; alpha-melanocyte-stimulating hormone; alphaMSH; alpha-MSH; BE; beta-endorphin; Beta-LPH; beta-melanocyte-stimulating hormone; beta-MSH; Clip; Corticotropin; Corticotropin-like intermediary peptide; corticotropin-lipotropin; Gamma-LPH; gamma-MSH; Lipotropin beta; lipotropin gamma; LPH; Melanocyte-stimulating hormone alpha; Melanocyte-stimulating hormone beta; Melanotropin alpha; melanotropin beta; Melanotropin gamma; met-enkephalin; MSH; NPP; opiomelanocortin prepropeptide; OTTHUMP00000119991; OTTHUMP00000200964; POC; Pomc; Pomc1; Pomc-1; Pomc2; Potential peptide; Precursor of MSH; pro-ACTH-endorphin; proopiomelanocortin; pro-opiomelanocortin; proopiomelanocortin (adrenocorticotropin/ beta-lipotropin/ alpha-melanocyte stimulating hormone/ beta-melanocyte stimulating hormone/ beta-endorphin); proopiomelanocortin preproprotein; proopiomelanocortin, beta (endorphin, beta); pro-opiomelanocortin-alpha; proopoimelanocortin, beta (endorphin, beta)

more info or order :

Invitrogen product webpage