CD205 Monoclonal Antibody (PN-15), Biotin | Invitrogen MA5-13362 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD205 Monoclonal Antibody (PN-15), Biotin

catalog :

MA5-13362

quantity :

500 µL

price :

US 446.00

clonality :

monoclonal

host :

mouse

conjugate :

biotin

clone name :

PN-15

reactivity :

human, rat

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 3

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human; 1:100	Yin W, Li J, Chan J. Sporadic haemangioblastoma of the kidney with rhabdoid features and focal CD10 expression: report of a case and literature review. Diagn Pathol. 2012;7:39 pubmed publisher
immunohistochemistry; human; 1:100	Sarsik B, Simsir A, Karaarslan S, Sen S. Mucinous tubular and spindle cell carcinoma of kidney and problems in diagnosis. Turk Patoloji Derg. 2011;27:116-26 pubmed publisher
immunohistochemistry; human; 1:100	Horlings H, van Laar R, Kerst J, Helgason H, Wesseling J, van Der Hoeven J, et al. Gene expression profiling to identify the histogenetic origin of metastatic adenocarcinomas of unknown primary. J Clin Oncol. 2008;26:4435-41 pubmed publisher

image

image 1 :

Formalin-fixed. Paraffin-embedded human renal cell carcinoma stained with RCC Marker antibody using peroxidase- conjugate and AEC chromogen. Note cytoplasmic staining of tumor cells

product information

Product Type :

Antibody

Product Name :

CD205 Monoclonal Antibody (PN-15), Biotin

Catalog # :

MA5-13362

Quantity :

500 µL

Price :

US 446.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human, Rat

Applications :

Immunohistochemistry (Paraffin): 2-4 µg/mL, Western Blot: Assay-dependent

Species :

Human, Rat

Clone :

PN-15

Isotype :

IgG1, kappa

Storage :

4° C

Description :

CD205 (LY25, Lymphocyte Antigen 75) is an integral membrane glycoprotein involved in antigen uptake, trafficking and presentation that improves the induction of antigen-specific T cell immunity. CD205 is highly expressed by CD8+ dendritic cells (DCs) and also expressed at different levels by bone marrow Gr1+ cells, Langerhans cells, (BMDC) bone marrow derived DCs and thymic epithelial cells. CD205 acts as an endocytic receptor that directs captured antigens to the extracellular space towards a specialized antigen processing region. Further, CD205 also prompts the reduced proliferation of B lymphocytes. Diseases associated with CD205 dysfunction include pneumonic plague and lipid pneumonia.

Immunogen :

Microsomal fraction of human renal cortical tissue homogenate

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 2-4 µg/mL, Western Blot: Assay-dependent

Aliases :

CA-IX; CD205; CLEC13B; C-type lectin domain family 13 member B; DCL-1 fusion; DEC205; DEC-205; DEC-205/CD205 protein; gp200; gp200-MR6; group VI C-type animal lectin; LY75; ly-75; Lymphocyte antigen 75; membrane antigen MN; P54/58N; pMW1; RGD1565962; RP23-10L17.4

more info or order :

Invitrogen product webpage