product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD68 Monoclonal Antibody (KP1)
catalog :
MA5-13324
quantity :
200 µL
price :
US 375.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
KP1
reactivity :
hamsters, baboons, human, mouse, rat, pigs , cat, domestic rabbit, rhesus macaque
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, mass cytometry
more info or order :
citations: 141
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; 1:150; loading ...; fig 9c
  • western blot; mouse; 1:250; loading ...; fig 9a
Hausrat T, Janiesch P, Breiden P, Lutz D, Hoffmeister Ullerich S, Hermans Borgmeyer I, et al. Disruption of tubulin-alpha4a polyglutamylation prevents aggregation of hyper-phosphorylated tau and microglia activation in mice. Nat Commun. 2022;13:4192 pubmed publisher
  • immunohistochemistry - frozen section; human; 1:100; fig s16b
Cho A, Jin Y, An Y, Kim J, Choi Y, Lee J, et al. Microfluidic device with brain extracellular matrix promotes structural and functional maturation of human brain organoids. Nat Commun. 2021;12:4730 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 4a
Shan Z, Li L, Atkins C, Wang M, Wen Y, Jeong J, et al. Chitinase 3-like-1 contributes to acetaminophen-induced liver injury by promoting hepatic platelet recruitment. elife. 2021;10: pubmed publisher
  • immunohistochemistry; human; 1:100; fig 1
Azzimonti B, Raimondo L, Squarzanti D, Rosso T, Zanetta P, Aluffi Valletti P, et al. Macrophages expressing TREM-1 are involved in the progression of HPV16-related oropharyngeal squamous cell carcinoma. Ann Med. 2021;53:541-550 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 1f
Yang Q, Ma Q, Xu J, Liu Z, Zou J, Shen J, et al. Prkaa1 Metabolically Regulates Monocyte/Macrophage Recruitment and Viability in Diet-Induced Murine Metabolic Disorders. Front Cell Dev Biol. 2020;8:611354 pubmed publisher
  • immunohistochemistry; mouse; 1:50; loading ...; fig 2d
Reventun P, Sanchez Esteban S, Cook A, Cuadrado I, Roza C, Moreno Gómez Toledano R, et al. Bisphenol A induces coronary endothelial cell necroptosis by activating RIP3/CamKII dependent pathway. Sci Rep. 2020;10:4190 pubmed publisher
  • immunohistochemistry; pigs ; 1:100; loading ...; fig 6h
Fang B, Ren X, Wang Y, Li Z, Zhao L, Zhang M, et al. Apolipoprotein E deficiency accelerates atherosclerosis development in miniature pigs. Dis Model Mech. 2018;11: pubmed publisher
  • immunohistochemistry - paraffin section; human; tbl s7
Chevrier S, Levine J, Zanotelli V, Silina K, Schulz D, Bacac M, et al. An Immune Atlas of Clear Cell Renal Cell Carcinoma. Cell. 2017;169:736-749.e18 pubmed publisher
  • mass cytometry; human; loading ...; fig 1j
See P, Dutertre C, Chen J, Günther P, McGovern N, Irac S, et al. Mapping the human DC lineage through the integration of high-dimensional techniques. Science. 2017;356: pubmed publisher
  • immunohistochemistry; human; loading ...; fig 1
Mahran A, Elgamal D, Ghafeer H, Abdel Maksoud S, Farrag A. Histological alterations in Leydig cells and macrophages in azoospermic men. Andrologia. 2017;49: pubmed publisher
  • immunohistochemistry - paraffin section; rat; 1:200; fig 5
Abdel Hamid A, Firgany A. Favorable outcomes of hydroxychloroquine in insulin resistance may be accomplished by adjustment of the endothelial dysfunction as well as the skewed balance of adipokines. Acta Histochem. 2016;118:560-573 pubmed publisher
  • immunohistochemistry; human
Ha D, Carpenter L, Koutakis P, Swanson S, Zhu Z, Hanna M, et al. Transforming growth factor-beta 1 produced by vascular smooth muscle cells predicts fibrosis in the gastrocnemius of patients with peripheral artery disease. J Transl Med. 2016;14:39 pubmed publisher
  • immunohistochemistry - frozen section; human; 1:200; fig s2
Alberti K, Xu Q. Biocompatibility and degradation of tendon-derived scaffolds. Regen Biomater. 2016;3:1-11 pubmed publisher
  • immunohistochemistry - paraffin section; human
Kursawe R, Dixit V, Scherer P, Santoro N, Narayan D, Gordillo R, et al. A Role of the Inflammasome in the Low Storage Capacity of the Abdominal Subcutaneous Adipose Tissue in Obese Adolescents. Diabetes. 2016;65:610-8 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100; fig 1c
Ok Atılgan A, Özdemir B, Akçay E, Ataol Demirkan Ã, Tekindal M, ÖzkardeÅŸ H. Role of tumor-associated macrophages in the Hexim1 and TGFβ/SMAD pathway, and their influence on progression of prostatic adenocarcinoma. Pathol Res Pract. 2016;212:83-92 pubmed publisher
  • flow cytometry; mouse; loading ...
Skeldon A, Morizot A, Douglas T, Santoro N, Kursawe R, Kozlitina J, et al. Caspase-12, but Not Caspase-11, Inhibits Obesity and Insulin Resistance. J Immunol. 2016;196:437-47 pubmed publisher
  • immunohistochemistry - paraffin section; human
Finkin S, Yuan D, Stein I, Taniguchi K, Weber A, Unger K, et al. Ectopic lymphoid structures function as microniches for tumor progenitor cells in hepatocellular carcinoma. Nat Immunol. 2015;16:1235-44 pubmed publisher
  • immunohistochemistry; rhesus macaque
Holder G, McGary C, Johnson E, Zheng R, John V, Sugimoto C, et al. Expression of the mannose receptor CD206 in HIV and SIV encephalitis: a phenotypic switch of brain perivascular macrophages with virus infection. J Neuroimmune Pharmacol. 2014;9:716-26 pubmed publisher
  • immunohistochemistry - paraffin section; human
Meshcheryakova A, Tamandl D, Bajna E, Stift J, Mittlboeck M, Svoboda M, et al. B cells and ectopic follicular structures: novel players in anti-tumor programming with prognostic power for patients with metastatic colorectal cancer. PLoS ONE. 2014;9:e99008 pubmed publisher
  • immunohistochemistry - paraffin section; rhesus macaque; 1:50
Batchelder C, Duru N, Lee C, Baker C, Swainson L, McCune J, et al. Myeloid-lymphoid ontogeny in the rhesus monkey (Macaca mulatta). Anat Rec (Hoboken). 2014;297:1392-406 pubmed publisher
  • immunocytochemistry; human
Tao K, Zeng H, Xiao D, Xiong A, Weng J, Kang B. Influences of IL-6R antibody on PMMA bone cement-mediated expression of OPG and RANKL in synovial fibroblasts. J Huazhong Univ Sci Technolog Med Sci. 2014;34:241-246 pubmed publisher
  • immunohistochemistry; human
Cetin C, Serdaroglu H, Tuzlali S. The importance of endometrial nerve fibers and macrophage cell count in the diagnosis of endometriosis. Iran J Reprod Med. 2013;11:405-14 pubmed
  • immunohistochemistry; mouse
Berres M, Lim K, Peters T, Price J, Takizawa H, Salmon H, et al. BRAF-V600E expression in precursor versus differentiated dendritic cells defines clinically distinct LCH risk groups. J Exp Med. 2014;211:669-83 pubmed publisher
  • immunohistochemistry; human; 1:100
Abdou A, Asaad N, Loay I, Shabaan M, Badr N. The prognostic role of tumor-associated macrophages and dendritic cells in classic Hodgkin's lymphoma. J Environ Pathol Toxicol Oncol. 2013;32:289-305 pubmed
  • immunohistochemistry; human
Mungan S, Karaguzel E, Turan C, Reis A. A giant primary sclerosing lipogranuloma of the scrotum. Turk Patoloji Derg. 2014;30:78-80 pubmed publisher
  • immunohistochemistry; human
Karakaya Y, Ozer E. The role of Hofbauer cells on the pathogenesis of early pregnancy loss. Placenta. 2013;34:1211-5 pubmed publisher
  • immunohistochemistry; human
Iancu T, Manov I, Shaoul R, Haimi M, Lerner A. What's in a name?-"Lipolysosome": ultrastructural features of a lipid-containing organelle. Ultrastruct Pathol. 2013;37:293-303 pubmed publisher
  • immunohistochemistry; rat; 1:200
Hsu D, Chen Y, Chu P, Periasamy S, Liu M. Protective effect of 3,4-methylenedioxyphenol (sesamol) on stress-related mucosal disease in rats. Biomed Res Int. 2013;2013:481827 pubmed publisher
  • immunohistochemistry; domestic rabbit; 1:100
Elgayar S, Eltony S, Othman M. Morphology of non-sensory epithelium during post-natal development of the rabbit vomeronasal organ. Anat Histol Embryol. 2014;43:282-93 pubmed publisher
  • immunohistochemistry; human; fig 2
Zhao Y, Li W, Lang R, Yang Y, Gao X, Zheng Y, et al. Primary acinic cell carcinoma of the breast: a case report and review of the literature. Int J Surg Pathol. 2014;22:177-81 pubmed publisher
  • immunohistochemistry; human; 1:100
Yuan R, Chen Y, He X, Wu X, Ke J, Zou Y, et al. CCL18 as an independent favorable prognostic biomarker in patients with colorectal cancer. J Surg Res. 2013;183:163-9 pubmed publisher
  • immunohistochemistry; human; 1:250
Soliman H, Rawal B, Fulp J, Lee J, Lopez A, Bui M, et al. Analysis of indoleamine 2-3 dioxygenase (IDO1) expression in breast cancer tissue by immunohistochemistry. Cancer Immunol Immunother. 2013;62:829-37 pubmed publisher
  • immunohistochemistry; human; 1:100
Kim N, Lee W, Lee J, Cho H. Multiple Jejunal Myeloid Sarcomas Presenting with Intestinal Obstruction in a Non-leukemic Patient: A Case Report with Ultrastructural Observations. Korean J Pathol. 2012;46:590-4 pubmed publisher
  • immunohistochemistry; rat; 1:200
Periasamy S, Hsu D, Chandrasekaran V, Liu M. Sesame oil accelerates healing of 2,4,6-trinitrobenzenesulfonic acid-induced acute colitis by attenuating inflammation and fibrosis. JPEN J Parenter Enteral Nutr. 2013;37:674-82 pubmed publisher
  • immunohistochemistry; rat
Yan H, Wu H, Ashton C, Tong C, Ying Q. Rats deficient for p53 are susceptible to spontaneous and carcinogen-induced tumorigenesis. Carcinogenesis. 2012;33:2001-5 pubmed publisher
  • immunohistochemistry; domestic rabbit; 1:100
Peng L, Li M, Xu Y, Zhang G, Yang C, Zhou Y, et al. Effect of Si-Miao-Yong-An on the stability of atherosclerotic plaque in a diet-induced rabbit model. J Ethnopharmacol. 2012;143:241-8 pubmed publisher
  • immunohistochemistry; human
Abdou A, Asaad N. Nodal marginal zone lymphoma associated with extensive epithelioid histiocytes. Rom J Morphol Embryol. 2012;53:417-20 pubmed
  • immunohistochemistry; rat
Li X, Jadlowiec C, Guo Y, Protack C, Ziegler K, Lv W, et al. Pericardial patch angioplasty heals via an Ephrin-B2 and CD34 positive cell mediated mechanism. PLoS ONE. 2012;7:e38844 pubmed publisher
  • immunohistochemistry; human; 1:200
Kacerovska D, Kerl K, Michal M, Filipova H, Vrtel R, Vanecek T, et al. Giant angiofibromas in tuberous sclerosis complex: a possible role for localized lymphedema in their pathogenesis. J Am Acad Dermatol. 2012;67:1319-26 pubmed publisher
  • immunohistochemistry; mouse
Smith D, Tan X, Raveendran V, Tawfik O, Stechschulte D, Dileepan K. Mast cell deficiency attenuates progression of atherosclerosis and hepatic steatosis in apolipoprotein E-null mice. Am J Physiol Heart Circ Physiol. 2012;302:H2612-21 pubmed publisher
  • immunohistochemistry; human
Tufan K, Sen O, Cekinmez M, Bolat F, Alkan O, Sarica F, et al. Comparison of E-selectin and the other inflammatory markers in lumbar disc herniation: a new promising therapeutical window for radicular pain. J Spinal Disord Tech. 2012;25:443-6 pubmed publisher
  • immunohistochemistry; human; 2 ug/ml
Peterson S, Poposki J, Nagarkar D, Chustz R, Peters A, Suh L, et al. Increased expression of CC chemokine ligand 18 in patients with chronic rhinosinusitis with nasal polyps. J Allergy Clin Immunol. 2012;129:119-27.e1-9 pubmed publisher
  • immunohistochemistry; human
Ayva S, Ozturk F, Obut H. Adenohibernoma: a rare breast tumor. Int J Surg Pathol. 2012;20:280-3 pubmed publisher
  • immunohistochemistry; human; 1:100; fig 3A
  • immunohistochemistry; mouse; fig S3
Ruffell B, Au A, Rugo H, Esserman L, Hwang E, Coussens L. Leukocyte composition of human breast cancer. Proc Natl Acad Sci U S A. 2012;109:2796-801 pubmed publisher
  • immunohistochemistry - paraffin section; baboons; 1:400
Prichard H, Manson R, Dibernardo L, Niklason L, Lawson J, Dahl S. An early study on the mechanisms that allow tissue-engineered vascular grafts to resist intimal hyperplasia. J Cardiovasc Transl Res. 2011;4:674-82 pubmed publisher
  • immunohistochemistry; human; 1:100
Yu G, Kong L, Qu G, Zhang Q, Wang W, Jiang L. Composite lymphoma in the anterior mediastinum: a case report and review of the literature. Diagn Pathol. 2011;6:60 pubmed publisher
  • immunohistochemistry; human; 1:5000
Kim H, Joo S, Yang D, Lee S, Choi S, Lim S. Carcinosarcoma of the pancreas: a unique case with emphasis on metaplastic transformation and the presence of undifferentiated pleomorphic high-grade sarcoma. J Gastrointestin Liver Dis. 2011;20:197-200 pubmed
  • immunohistochemistry; rat; 1:200
Periasamy S, Hsu D, Chen S, Yang S, Chandrasekaran V, Liu M. Therapeutic sesamol attenuates monocrotaline-induced sinusoidal obstruction syndrome in rats by inhibiting matrix metalloproteinase-9. Cell Biochem Biophys. 2011;61:327-36 pubmed publisher
  • immunohistochemistry; human
Susleyici Duman B, Zengin K, Kayhan F, Koldemir M, Dagistanli F, Cagatay P, et al. FTO mRNA expression in extremely obese and type 2 diabetic human omental and subcutaneous adipose tissues. Obes Surg. 2011;21:1766-73 pubmed publisher
  • immunohistochemistry; human; 1:8000
Gdynia G, Schnitzler P, Brunner E, Kandolf R, Blaker H, Daum E, et al. Sudden death of an immunocompetent young adult caused by novel (swine origin) influenza A/H1N1-associated myocarditis. Virchows Arch. 2011;458:371-6 pubmed publisher
  • immunohistochemistry; human
Glynn S, Boersma B, Dorsey T, Yi M, Yfantis H, Ridnour L, et al. Increased NOS2 predicts poor survival in estrogen receptor-negative breast cancer patients. J Clin Invest. 2010;120:3843-54 pubmed publisher
  • immunohistochemistry; human; 1:50
Helin M, Rönkkö S, Puustjarvi T, Teräsvirta M, Ollikainen M, Uusitalo H. Conjunctival inflammatory cells and their predictive role for deep sclerectomy in primary open-angle glaucoma and exfoliation glaucoma. J Glaucoma. 2011;20:172-8 pubmed publisher
  • immunohistochemistry; human
Chen Z, Ichetovkin M, Kurtz M, Zycband E, Kawka D, Woods J, et al. Cholesterol in human atherosclerotic plaque is a marker for underlying disease state and plaque vulnerability. Lipids Health Dis. 2010;9:61 pubmed publisher
  • immunohistochemistry; rat; 1:100
Hsiao I, Lin K, Chang S, Yen T, Chen T, Yeh T. Impaired liver regeneration of steatotic rats after portal vein ligation: a particular emphasis on (99m)Tc-DISIDA scintigraphy and adiponectin signaling. J Hepatol. 2010;52:540-9 pubmed publisher
  • immunohistochemistry; human
Lee W, Kim S, Ryu W. Progression and observational frequency of atheromatous plaques in autopsied coronary arteries. Korean Circ J. 2009;39:399-407 pubmed publisher
  • immunohistochemistry; human
Zyada M. Expression of matrix metalloproteinase-9 and significance of a macrophage assay in eosinophilic granuloma. Ann Diagn Pathol. 2009;13:367-72 pubmed publisher
  • immunohistochemistry; pigs
Lee J, Ryu Y, Ahn J, Kim M, Lee T, Kim J. The effect of lyophilization on graft acceptance in experimental xenotransplantation using porcine cornea. Artif Organs. 2010;34:37-45 pubmed publisher
  • immunohistochemistry; human
Lee W, Kim S, Hong S, Lee T, Park E, Kim H, et al. Atherosclerotic progression attenuates the expression of Nogo-B in autopsied coronary artery: pathology and virtual histology intravascular ultrasound analysis. J Korean Med Sci. 2009;24:596-604 pubmed publisher
  • immunohistochemistry; human
Kurago Z, Lam ubol A, Stetsenko A, De La Mater C, Chen Y, Dawson D. Lipopolysaccharide-squamous cell carcinoma-monocyte interactions induce cancer-supporting factors leading to rapid STAT3 activation. Head Neck Pathol. 2008;2:1-12 pubmed publisher
  • immunohistochemistry; hamsters; 1:400
Guo T, Chen W, Zhang C, Zhao Y, Zhang Y. Chymase activity is closely related with plaque vulnerability in a hamster model of atherosclerosis. Atherosclerosis. 2009;207:59-67 pubmed publisher
  • immunohistochemistry; human
Wang W, Bergh A, Damber J. Increased p53 immunoreactivity in proliferative inflammatory atrophy of prostate is related to focal acute inflammation. APMIS. 2009;117:185-95 pubmed publisher
  • immunohistochemistry; human
Martin D, Boersma B, Yi M, Reimers M, Howe T, Yfantis H, et al. Differences in the tumor microenvironment between African-American and European-American breast cancer patients. PLoS ONE. 2009;4:e4531 pubmed publisher
  • immunohistochemistry; rat
Liao C, Lasbury M, Wang S, Zhang C, Durant P, Murakami Y, et al. Pneumocystis mediates overexpression of antizyme inhibitor resulting in increased polyamine levels and apoptosis in alveolar macrophages. J Biol Chem. 2009;284:8174-84 pubmed publisher
  • immunohistochemistry; human
Ye D, Kraaijeveld A, Grauss R, Willems S, van Vark van der Zee L, de Jager S, et al. Reduced leucocyte cholesteryl ester transfer protein expression in acute coronary syndromes. J Intern Med. 2008;264:571-85 pubmed publisher
  • immunohistochemistry; human; 1:40
Akbulut M, Sorkun H, Bir F, Eralp A, Duzcan E. Chorangiosis: the potential role of smoking and air pollution. Pathol Res Pract. 2009;205:75-81 pubmed publisher
  • immunohistochemistry; rat
Chen Y, Jiang X, Gong J. Recombinant human granulocyte colony-stimulating factor enhanced the resolution of venous thrombi. J Vasc Surg. 2008;47:1058-65 pubmed publisher
  • immunohistochemistry; domestic rabbit; 1:10
Rönkkö S, Rekonen P, Sihvola R, Kaarniranta K, Puustjarvi T, Teräsvirta M, et al. Histopathology of the three implanted degradable biopolymers in rabbit eye. J Biomed Mater Res A. 2009;88:717-24 pubmed publisher
  • immunohistochemistry; rhesus macaque
  • immunohistochemistry; domestic rabbit
Nuttall J, Thake D, Lewis M, Ferkany J, Romano J, Mitchnick M. Concentrations of dapivirine in the rhesus macaque and rabbit following once daily intravaginal administration of a gel formulation of [14C]dapivirine for 7 days. Antimicrob Agents Chemother. 2008;52:909-14 pubmed
  • immunohistochemistry; human; 1:40
Akbulut M, Gunhan Bilgen I, Zekioglu O, Duygulu G, Oktay A, Ozdemir N. Fine needle aspiration cytology of inflammatory myofibroblastic tumour (inflammatory pseudotumour) of the breast: a case report and review of the literature. Cytopathology. 2007;18:384-7 pubmed
  • immunohistochemistry; human; 1:150
Goyal R, Vaiphei K, Vankalakunti M, Marwaha R. Pathology teach and tell disseminated candidiasis in an infant with acute myeloid leukemia without prior chemotherapy. Fetal Pediatr Pathol. 2006;25:333-8 pubmed
  • immunohistochemistry; human
Wang W, Bergh A, Damber J. Increased expression of CCAAT/enhancer-binding protein beta in proliferative inflammatory atrophy of the prostate: relation with the expression of COX-2, the androgen receptor, and presence of focal chronic inflammation. Prostate. 2007;67:1238-46 pubmed
  • immunohistochemistry; human; 1:10
Rönkkö S, Rekonen P, Kaarniranta K, Puustjarvi T, Teräsvirta M, Uusitalo H. Phospholipase A2 in chamber angle of normal eyes and patients with primary open angle glaucoma and exfoliation glaucoma. Mol Vis. 2007;13:408-17 pubmed
  • immunohistochemistry; human; 1:100
Kirma N, Hammes L, Liu Y, Nair H, Valente P, Kumar S, et al. Elevated expression of the oncogene c-fms and its ligand, the macrophage colony-stimulating factor-1, in cervical cancer and the role of transforming growth factor-beta1 in inducing c-fms expression. Cancer Res. 2007;67:1918-26 pubmed
  • immunohistochemistry; rat; 1:100
Liu E, Chen M, Yeh T, Ho Y, Wu R, Chen T, et al. A useful model to audit liver resolution from cirrhosis in rats using functional proteomics. J Surg Res. 2007;138:214-23 pubmed
  • immunohistochemistry; human
Prueitt R, Boersma B, Howe T, Goodman J, Thomas D, Ying L, et al. Inflammation and IGF-I activate the Akt pathway in breast cancer. Int J Cancer. 2007;120:796-805 pubmed
  • immunohistochemistry; human; 1:1000
Choi J, Lee J, Kim A, Kim C, Chae Y, Kim I. Follicular dendritic cell sarcoma arising in the dura mater of the spine. Arch Pathol Lab Med. 2006;130:1718-21 pubmed
  • immunohistochemistry; human
Tanaka H, Hashimoto M, Fujii M, Tanaka N, Suzuki K, Saikai T, et al. Reduction of eosinophils in small airways by inhaled steroids is insufficient in patients with adult asthma. Allergol Int. 2006;55:305-9 pubmed
  • immunohistochemistry; rat
Sakallioglu A, Basaran O, Ozdemir B, Arat Z, Yucel M, Haberal M. Local and systemic interactions related to serum transforming growth factor-beta levels in burn wounds of various depths. Burns. 2006;32:980-5 pubmed
  • immunohistochemistry; human; 1:200
Boudova L, Kazakov D, Jindra P, Sima R, Vanecek T, Kuntscher V, et al. Primary cutaneous histiocyte and neutrophil-rich CD30+ and CD56+ anaplastic large-cell lymphoma with prominent angioinvasion and nerve involvement in the forehead and scalp of an immunocompetent woman. J Cutan Pathol. 2006;33:584-9 pubmed
  • immunohistochemistry; human; 1:200
Skalova A, Gnepp D, Simpson R, Lewis J, Janssen D, Sima R, et al. Clonal nature of sclerosing polycystic adenosis of salivary glands demonstrated by using the polymorphism of the human androgen receptor (HUMARA) locus as a marker. Am J Surg Pathol. 2006;30:939-44 pubmed
  • immunohistochemistry; rat
Sakallioglu A, Basaran O, Karakayali H, Ozdemir B, Yucel M, Arat Z, et al. Interactions of systemic immune response and local wound healing in different burn depths: an experimental study on rats. J Burn Care Res. 2006;27:357-66 pubmed
  • immunohistochemistry; human
Aydin N, Celik O, Hascalik S, Edali M. Atypical reactive ovarian surface epithelium, a pitfall in pathologic assessment. Int J Gynecol Cancer. 2006;16 Suppl 1:207-10 pubmed
  • immunocytochemistry; human; 1:100
Shehata S, Sharma H, Mooi W, Tibboel D. Pulmonary hypertension in human newborns with congenital diaphragmatic hernia is associated with decreased vascular expression of nitric-oxide synthase. Cell Biochem Biophys. 2006;44:147-55 pubmed
  • immunohistochemistry; human
Avunduk A, Avunduk M, Pazarli H, Oguz V, Varnell E, Kaufman H, et al. Immunohistochemical analysis of orbital connective tissue specimens of patients with active Graves ophthalmopathy. Curr Eye Res. 2005;30:631-8 pubmed
  • immunohistochemistry; human
Kim K, Han E, Lee E, Park H, Kim I, Kim Y. Epstein-Barr virus infection in sarcomatoid renal cell carcinoma tissues. BJU Int. 2005;96:547-52 pubmed
  • immunohistochemistry; human
Zhang Y, Yuan F, Jia G, Zhang J, Hu L, Huang L, et al. CIK cells from patients with HCC possess strong cytotoxicity to multidrug-resistant cell line Bel-7402/R. World J Gastroenterol. 2005;11:3339-45 pubmed
  • immunohistochemistry; human
Uluoglu O, Akyurek N, Uner A, Coskun U, Ozdemir A, Gokcora N. Interdigitating dendritic cell tumor with breast and cervical lymph-node involvement: a case report and review of the literature. Virchows Arch. 2005;446:546-54 pubmed
  • immunohistochemistry; human
Acikalin M, Tel N, Oner U, Pasaoglu O, Donmez T. Epithelioid angiomyolipoma of the kidney. Int J Urol. 2005;12:204-7 pubmed
  • immunohistochemistry; human
Acikalin M, Kabukcuoglu S, Can C. Sarcomatoid carcinoma of the renal pelvis with giant cell tumor-like features: case report with immunohistochemical findings. Int J Urol. 2005;12:199-203 pubmed
Doppler C, Messner B, Mimler T, Schachner B, Rezk M, Ganh xf6 r C, et al. Noncanonical atherosclerosis as the driving force in tricuspid aortic valve associated aneurysms - A trace collection. J Lipid Res. 2023;64:100338 pubmed publisher
Gough M, Singh D, Singh B, Kaushal D, Mehra S. System-wide identification of myeloid markers of TB disease and HIV-induced reactivation in the macaque model of Mtb infection and Mtb/SIV co-infection. Front Immunol. 2022;13:777733 pubmed publisher
Yang F, Zeng Z, Li Y, Zhang D, Wei F, Zhao H, et al. The prognostic value of a 4-factor neoimmunologic score system in non-small cell lung cancer. J Leukoc Biol. 2022;112:1605-1619 pubmed publisher
Li G, Li X, Yang L, Wang S, Dai Y, Fekry B, et al. Adipose tissue-specific ablation of Ces1d causes metabolic dysregulation in mice. Life Sci Alliance. 2022;5: pubmed publisher
Xue M, Sheng W, Song X, Shi Y, Geng Z, Shen L, et al. Atractylenolide III ameliorates spinal cord injury in rats by modulating microglial/macrophage polarization. CNS Neurosci Ther. 2022;28:1059-1071 pubmed publisher
Leader C, Wilkins G, Walker R. The effect of spironolactone on cardiac and renal fibrosis following myocardial infarction in established hypertension in the transgenic Cyp1a1Ren2 rat. PLoS ONE. 2021;16:e0260554 pubmed publisher
Gao Z, Lu A, Daquinag A, Yu Y, Huard M, Tseng C, et al. Partial Ablation of Non-Myogenic Progenitor Cells as a Therapeutic Approach to Duchenne Muscular Dystrophy. Biomolecules. 2021;11: pubmed publisher
Dalba x15f x131 E, Akg xfc l x. The effectiveness of methotrexate and low-dose steroid therapy in the treatment of idiopathic granulomatous mastitis. Adv Clin Exp Med. 2021;30:1091-1097 pubmed publisher
Zhang L, Zhou L, Bao L, Liu J, Zhu H, Lv Q, et al. SARS-CoV-2 crosses the blood-brain barrier accompanied with basement membrane disruption without tight junctions alteration. Signal Transduct Target Ther. 2021;6:337 pubmed publisher
Yu T, Zhang J, Zhu W, Wang X, Bai Y, Feng B, et al. Chondrogenesis mediates progression of ankylosing spondylitis through heterotopic ossification. Bone Res. 2021;9:19 pubmed publisher
Black E, Phillips J, Seminetta J, Bailes J, Lee J, Finan J. The effect of dietary supplementation with high- or low-dose omega-3 fatty acid on inflammatory pathology after traumatic brain injury in rats. Transl Neurosci. 2021;12:76-82 pubmed publisher
Nolan R, Reeb K, Rong Y, Matt S, Johnson H, Runner K, et al. Dopamine activates NF-κB and primes the NLRP3 inflammasome in primary human macrophages. Brain Behav Immun Health. 2020;2: pubmed publisher
Bonilha V, Bell B, Hu J, Milliner C, Pauer G, Hagstrom S, et al. Geographic Atrophy: Confocal Scanning Laser Ophthalmoscopy, Histology, and Inflammation in the Region of Expanding Lesions. Invest Ophthalmol Vis Sci. 2020;61:15 pubmed publisher
Stephens C, Morrison R, McLaughlin M, Orr K, Tersey S, Scott Moncrieff J, et al. Oligomeric collagen as an encapsulation material for islet/β-cell replacement: effect of islet source, dose, implant site, and administration format. Am J Physiol Endocrinol Metab. 2020;319:E388-E400 pubmed publisher
Leader C, Kelly D, Sammut I, Wilkins G, Walker R. Spironolactone mitigates, but does not reverse, the progression of renal fibrosis in a transgenic hypertensive rat. Physiol Rep. 2020;8:e14448 pubmed publisher
Liu Q, Su L, Sun C, Jiao L, Miao Y, Xu M, et al. Melatonin alleviates morphine analgesic tolerance in mice by decreasing NLRP3 inflammasome activation. Redox Biol. 2020;34:101560 pubmed publisher
Ryu G, Bae J, Kim J, Kim E, Lyu L, Chung Y, et al. Role of IL-17A in Chronic Rhinosinusitis With Nasal Polyp. Allergy Asthma Immunol Res. 2020;12:507-522 pubmed publisher
Sun X, Xiao L, Chen J, Chen X, Chen X, Yao S, et al. DNA methylation is involved in the pathogenesis of osteoarthritis by regulating CtBP expression and CtBP-mediated signaling. Int J Biol Sci. 2020;16:994-1009 pubmed publisher
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image
image 1 :
Invitrogen MA5-13324 image 1
Formalin-fixed, paraffin-embedded human tonsil stained with CD68 antibody using peroxidase-conjugate and AEC chromogen. Note intense cytoplasmic staining of macrophages.
product information
Product Type :
Antibody
Product Name :
CD68 Monoclonal Antibody (KP1)
Catalog # :
MA5-13324
Quantity :
200 µL
Price :
US 375.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Feline, Human, Non-human primate, Rat
Applications :
Immunocytochemistry: 5 µg/mL, Immunohistochemistry (Paraffin): 1 µg/mL
Species :
Feline, Human, Non-human primate, Rat
Clone :
KP1
Isotype :
IgG1, kappa
Storage :
4° C
Description :
CD68 (Macrosialin) is a 110 kDa integral membrane glycoprotein predominantly expressed on the intracellular lysomsomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes. Also, CD68 could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 is expressed by interdigitating reticulum cells in tonsil and some histiocytic lymphoma or histiocytosis, acute myeloid leukemia (AML), and granulocytic sarcoma. Elevated expression of CD68 has been demonstrated on CD34+ cells in various human malignancies, including several Acute Myeloid Leukemia studies.
Immunogen :
Subcellular fraction of human alveolar macrophages
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 5 µg/mL, Immunohistochemistry (Paraffin): 1 µg/mL
Aliases :
CD68; CD68 antigen; CD68 molecule; GP110; Lamp4; macrophage antigen CD68; macrosialin; Scard1; scavenger receptor class D, member 1; similar to CD68 antigen
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA