NGFR Monoclonal Antibody (NGFR5) | Invitrogen MA5-13314 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

NGFR Monoclonal Antibody (NGFR5)

catalog :

MA5-13314

quantity :

500 µL

price :

US 496.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

NGFR5

reactivity :

black ferret, human, rat, cat, domestic rabbit

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, blocking or activating experiments

more info or order :

Invitrogen product webpage

citations: 21

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human	Rafii M, Baumann T, Bakay R, OSTROVE J, Siffert J, Fleisher A, et al. A phase1 study of stereotactic gene delivery of AAV2-NGF for Alzheimer's disease. Alzheimers Dement. 2014;10:571-81 pubmed publisher
immunocytochemistry; human immunohistochemistry; human	Reinisch C, Tschachler E. The dimensions and characteristics of the subepidermal nerve plexus in human skin--terminal Schwann cells constitute a substantial cell population within the superficial dermis. J Dermatol Sci. 2012;65:162-9 pubmed publisher
immunohistochemistry; human; 1:15,000	Perez S, Getova D, He B, Counts S, Geula C, Désiré L, et al. Rac1b increases with progressive tau pathology within cholinergic nucleus basalis neurons in Alzheimer's disease. Am J Pathol. 2012;180:526-40 pubmed publisher
blocking or activating experiments; human; 10 ug/ml	Colombo E, Romaggi S, Medico E, Menon R, Mora M, Falcone C, et al. Human neurotrophin receptor p75NTR defines differentiation-oriented skeletal muscle precursor cells: implications for muscle regeneration. J Neuropathol Exp Neurol. 2011;70:133-42 pubmed publisher
immunohistochemistry; human; 1:10	Chan M, Tahan S. Low-affinity nerve growth factor receptor (P75 NGFR) as a marker of perineural invasion in malignant melanomas. J Cutan Pathol. 2010;37:336-43 pubmed publisher
immunohistochemistry; human; 1:100	Mosnier J, Jarry A, Camdessanche J, Antoine J, Laboisse C. In situ evidence of involvement of Schwann cells in ulcerative colitis: autocrine and paracrine signaling by A disintegrin and metalloprotease-17-mediated tumor necrosis factor alpha production. Hum Pathol. 2009;40:1159-67 pubmed publisher
immunohistochemistry; human; 1:5, 1:10	Ceausu M, Curca C, Ardeleanu C, Dermengiu D. Immunophenotypical pleomorphism expression in sudden cardiac death. Rom J Morphol Embryol. 2008;49:315-20 pubmed
immunohistochemistry; human; 1:200	Bai M, Papoudou Bai A, Karatzias G, Doukas M, Goussia A, Stefanaki K, et al. Immunohistochemical expression patterns of neural and neuroendocrine markers, the neural growth factor receptors and the beta-tubulin II and IV isotypes in human thymus. Anticancer Res. 2008;28:295-303 pubmed
immunohistochemistry; human	Becktor K, Nolting D, Becktor J, Kjaer I. Immunohistochemical localization of epithelial rests of Malassez in human periodontal membrane. Eur J Orthod. 2007;29:350-3 pubmed
immunohistochemistry; human; 1:200	Ødegaard E, Staff A, Abeler V, Kopolovic J, Onsrud M, Lazarovici P, et al. The activated nerve growth factor receptor p-TrkA is selectively expressed in advanced-stage ovarian carcinoma. Hum Pathol. 2007;38:140-6 pubmed
immunohistochemistry; human; 1:10,000	Dees W, Hiney J, McArthur N, Johnson G, Dissen G, Ojeda S. Origin and ontogeny of mammalian ovarian neurons. Endocrinology. 2006;147:3789-96 pubmed
immunoprecipitation; rat	Rocha A, Risberg B, Magalhães J, Trovisco V, de Castro I, Lazarovici P, et al. The p75 neurotrophin receptor is widely expressed in conventional papillary thyroid carcinoma. Hum Pathol. 2006;37:562-8 pubmed
flow cytometry; human; 4 ug/ml	Nassenstein C, Möhring U, Luttmann W, Virchow J, Braun A. Differential expression of the neurotrophin receptors p75NTR, TrkA, TrkB and TrkC in human peripheral blood mononuclear cells. Exp Toxicol Pathol. 2006;57 Suppl 2:55-63 pubmed
flow cytometry; human; 1:40 western blot; human; 1:500	Giraud S, Lautrette C, Bessette B, Decourt C, Mathonnet M, Jauberteau M. Modulation of Fas-induced apoptosis by p75 neurotrophin receptor in a human neuroblastoma cell line. Apoptosis. 2005;10:1271-83 pubmed
	Velasco Aviles S, Patel N, Casillas Bajo A, Frutos Rinc xf3 n L, Velasco E, Gallar J, et al. A genetic compensatory mechanism regulated by Jun and Mef2d modulates the expression of distinct class IIa Hdacs to ensure peripheral nerve myelination and repair. elife. 2022;11: pubmed publisher
	Hawkins F, Suzuki S, Beermann M, Barillà C, Wang R, Villacorta Martin C, et al. Derivation of Airway Basal Stem Cells from Human Pluripotent Stem Cells. Cell Stem Cell. 2021;28:79-95.e8 pubmed publisher
	Castellini C, Mattioli S, Dal Bosco A, Collodel G, Pistilli A, Stabile A, et al. In vitro effect of nerve growth factor on the main traits of rabbit sperm. Reprod Biol Endocrinol. 2019;17:93 pubmed publisher
	Biswas S, Mandal G, Roy Chowdhury S, Purohit S, Payne K, Anadon C, et al. Exosomes Produced by Mesenchymal Stem Cells Drive Differentiation of Myeloid Cells into Immunosuppressive M2-Polarized Macrophages in Breast Cancer. J Immunol. 2019;203:3447-3460 pubmed publisher
	Bowles K, TCW J, Qian L, Jadow B, Goate A. Reduced variability of neural progenitor cells and improved purity of neuronal cultures using magnetic activated cell sorting. PLoS ONE. 2019;14:e0213374 pubmed publisher
	Ehrmantant W, Graham W, Towfighi J, Mackay D, Ehrlich H. A histological and anatomical profile of pacinian corpuscles from Dupuytren's contracture and the expression of nerve growth factor receptor. Plast Reconstr Surg. 2004;114:721-7 pubmed
	Nassenstein C, Braun A, Erpenbeck V, Lommatzsch M, Schmidt S, Krug N, et al. The neurotrophins nerve growth factor, brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin-4 are survival and activation factors for eosinophils in patients with allergic bronchial asthma. J Exp Med. 2003;198:455-67 pubmed

product information

Product Type :

Antibody

Product Name :

NGFR Monoclonal Antibody (NGFR5)

Catalog # :

MA5-13314

Quantity :

500 µL

Price :

US 496.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Feline, Ferret, Human, Non-human primate, Rabbit, Rat

Applications :

Flow Cytometry: 2 µg/test, Immunocytochemistry: 1:10-1:200, Western Blot: 1:10-1:200

Species :

Feline, Ferret, Human, Non-human primate, Rabbit, Rat

Clone :

NGFR5

Isotype :

IgG1, kappa

Storage :

4° C

Description :

Neurotrophic factors control the survival, differentiation and maintenance of neurons in the peripheral and central nervous systems, and of other neural crest-derived cell types. Developing sympathetic neurons are absolutely dependent upon nerve growth factor (NGF) during the period of target competition in vivo. Antibodies reacting specifically with NGFR p75 are useful tools in the detection and characterization of NGFR p75, to enhance our understanding of a wide range of phenomena in the development, plasticity and repair of the nervous system.

Immunogen :

NGFR from A875 melanoma cells

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 2 µg/test, Immunocytochemistry: 1:10-1:200, Western Blot: 1:10-1:200

Aliases :

CD271; CD271 antigen; Gp80-LNGFR; LNGFR; low affinity nerve growth factor receptor; low affinity neurotrophin receptor p75NTR; LOW QUALITY PROTEIN: tumor necrosis factor receptor superfamily member 16; low-affinity nerve growth factor receptor; nerve growth factor receptor; nerve growth factor receptor (TNFR superfamily, member 16); nerve growth factor receptor, fast; NGF receptor; NGFR; NGR; p75; p-75; p75 ICD; p75 neurotrophin receptor; p75 ntr; p75(NTR); p75NGFR; p75NTR; RNNGFRR; TNFR superfamily, member 16; Tnfrsf16; TNR16; Tumor necrosis factor receptor superfamily member 16

more info or order :

Invitrogen product webpage