CD5 Monoclonal Antibody (4C7) | Invitrogen MA5-13308 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD5 Monoclonal Antibody (4C7)

catalog :

MA5-13308

quantity :

500 µL

price :

US 446.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

4C7

reactivity :

human

application :

western blot, immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 27

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; human; loading ...; tbl 2	Debliquis A, Voirin J, Harzallah I, Maurer M, Lerintiu F, Drenou B, et al. Cytomorphology and flow cytometry of brain biopsy rinse fluid enables faster and multidisciplinary diagnosis of large B-cell lymphoma of the central nervous system. Cytometry B Clin Cytom. 2018;94:182-188 pubmed publisher
immunohistochemistry - paraffin section; human; 1:20; loading ...	Burger J, Landau D, Taylor Weiner A, Bozic I, Zhang H, Sarosiek K, et al. Clonal evolution in patients with chronic lymphocytic leukaemia developing resistance to BTK inhibition. Nat Commun. 2016;7:11589 pubmed publisher
immunohistochemistry; human; 1:50	Wang T, Xu C, Liu S, Kan B, Ran Y, Liu W, et al. Clinicopathology, immunophenotype, T cell receptor gene rearrangement, Epstein-Barr virus status and p53 gene mutation of cutaneous extranodal NK/T-cell lymphoma, nasal-type. Chin Med J (Engl). 2013;126:1281-7 pubmed
immunohistochemistry; human; 1:150	Munari E, Rinaldi M, Ambrosetti A, Bonifacio M, Bonalumi A, Chilosi M, et al. Absence of TCL1A expression is a useful diagnostic feature in splenic marginal zone lymphoma. Virchows Arch. 2012;461:677-85 pubmed publisher
immunohistochemistry - paraffin section; human	He X, Li B, Yang S, Lu N, Zhang X, Zou S, et al. R-CHOP regimen can significantly decrease the risk of disease relapse and progression in patients with non-germinal center B-cell subtype diffuse large B-cell lymphoma. Chin J Cancer. 2012;31:306-14 pubmed publisher
immunohistochemistry; human	Tralongo V, Becchina G, Nagar C, Ottoveggio G, Mason S, Seno B, et al. Primary follicular lymphoma of the epididymis positive for t(14;18)(q32;q21)/IGH-BCL2 and negative for BCL2 protein expression: a case report. J Med Case Rep. 2012;6:24 pubmed publisher
immunohistochemistry; human; 1:100	Chang I, Chen H, Ma M, Huang W. Anaplastic large cell lymphoma with paraneoplastic leukocytosis: a clinicopathological analysis of five cases. APMIS. 2011;119:794-801 pubmed publisher
immunohistochemistry; human; 1:20	Huh Y, Schweighofer C, Ketterling R, Knudson R, Vega F, Kim J, et al. Chronic lymphocytic leukemia with t(14;19)(q32;q13) is characterized by atypical morphologic and immunophenotypic features and distinctive genetic features. Am J Clin Pathol. 2011;135:686-96 pubmed publisher
immunohistochemistry; human	Khoury T, Chandrasekhar R, Wilding G, Tan D, Cheney R. Tumour eosinophilia combined with an immunohistochemistry panel is useful in the differentiation of type B3 thymoma from thymic carcinoma. Int J Exp Pathol. 2011;92:87-96 pubmed publisher
immunohistochemistry; human	Konoplev S, Lin P, Qiu X, Medeiros L, Yin C. Clonal relationship of extranodal marginal zone lymphomas of mucosa-associated lymphoid tissue involving different sites. Am J Clin Pathol. 2010;134:112-8 pubmed publisher
immunohistochemistry; human	Li T, Medeiros L, Lin P, Yin H, Littlejohn M, Im W, et al. Immunohistochemical profile and fluorescence in situ hybridization analysis of diffuse large B-cell lymphoma in northern China. Arch Pathol Lab Med. 2010;134:759-65 pubmed publisher
immunohistochemistry; human; 1:40	Lee S, Ogilvie R, Dupre M, Gao Z. Intravascular lymphocytosis in acute appendicitis: potential mimicry of chronic lymphocytic leukaemia. Histopathology. 2009;55:660-4 pubmed publisher
immunohistochemistry; human; 1:50	Bhagavathi S, Micale M, Douglas Nikitin V, Ballouz S, Neumann K, Blenc A. Composite biclonal marginal zone lymphoma of lung and chronic lymphocytic leukemia: pathologic, phenotypic, cytogenetic, and molecular study. Int J Surg Pathol. 2011;19:377-81 pubmed publisher
immunohistochemistry; human; 1:20	Huh Y, Lin K, Vega F, Schlette E, Yin C, Keating M, et al. MYC translocation in chronic lymphocytic leukaemia is associated with increased prolymphocytes and a poor prognosis. Br J Haematol. 2008;142:36-44 pubmed publisher
immunohistochemistry; human; 1:25	Roullet M, Sargent R, Pasha T, Cajiao I, Elstrom R, Smith T, et al. ZAP70 expression assessed by immunohistochemistry on peripheral blood: a simple prognostic assay for patients with chronic lymphocytic leukemia. Appl Immunohistochem Mol Morphol. 2007;15:471-6 pubmed
immunohistochemistry; human; 1:20	Edelweiss M, Medeiros L, Suster S, Moran C. Lymph node involvement by Langerhans cell histiocytosis: a clinicopathologic and immunohistochemical study of 20 cases. Hum Pathol. 2007;38:1463-9 pubmed
immunohistochemistry; human	Asaad N, Abd El Wahed M, Dawoud M. Diagnosis and prognosis of B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma (B-CLL/SLL) and mantle cell lymphoma (MCL). J Egypt Natl Canc Inst. 2005;17:279-90 pubmed
immunohistochemistry; human; 1:20	Vega F, Padula A, Valbuena J, Stancu M, Jones D, Medeiros L. Lymphomas involving the pleura: a clinicopathologic study of 34 cases diagnosed by pleural biopsy. Arch Pathol Lab Med. 2006;130:1497-502 pubmed
immunohistochemistry; human; 1:20	Yin C, Medeiros L, Cromwell C, Mehta A, Lin P, Luthra R, et al. Sequence analysis proves clonal identity in five patients with typical and blastoid mantle cell lymphoma. Mod Pathol. 2007;20:1-7 pubmed
immunohistochemistry; human	Smit L, Hallaert D, Spijker R, de Goeij B, Jaspers A, Kater A, et al. Differential Noxa/Mcl-1 balance in peripheral versus lymph node chronic lymphocytic leukemia cells correlates with survival capacity. Blood. 2007;109:1660-8 pubmed
immunohistochemistry; human	Yin C, Medeiros L, Abruzzo L, Jones D, Farhood A, Thomazy V. EBV-associated B- and T-cell posttransplant lymphoproliferative disorders following primary EBV infection in a kidney transplant recipient. Am J Clin Pathol. 2005;123:222-8 pubmed
	Suzuki M, Muroi A, Nojima M, Numata A, Takasaki H, Sakai R, et al. Utility of a Reverse Phase Protein Array to Evaluate Multiple Biomarkers in Diffuse Large B-Cell Lymphoma. Proteomics Clin Appl. 2020;14:e1900091 pubmed publisher
	He H, Wang M, Huang W. Infectious mononucleosis mimicking malignant T-cell lymphoma in the nasopharynx: a case report and review of the literature. Int J Clin Exp Pathol. 2013;6:105-9 pubmed
	Oz Puyan F, Bilgi S, Unlu E, Yalcin O, Altaner S, Demir M, et al. Inflammatory pseudotumor of the spleen with EBV positivity: report of a case. Eur J Haematol. 2004;72:285-91 pubmed
	Lin P, Bueso Ramos C, Wilson C, Mansoor A, Medeiros L. Waldenstrom macroglobulinemia involving extramedullary sites: morphologic and immunophenotypic findings in 44 patients. Am J Surg Pathol. 2003;27:1104-13 pubmed
	Theate I, Michaux L, Dardenne S, Guiot Y, Briere J, Emile F, et al. Epstein-Barr virus-associated lymphoproliferative disease occurring in a patient with sarcoidosis treated by methotrexate and methylprednisolone. Eur J Haematol. 2002;69:248-53 pubmed
	Abruzzo L, Rosales C, Medeiros L, Vega F, Luthra R, Manning J, et al. Epstein-Barr virus-positive B-cell lymphoproliferative disorders arising in immunodeficient patients previously treated with fludarabine for low-grade B-cell neoplasms. Am J Surg Pathol. 2002;26:630-6 pubmed

image

image 1 :

Formalin-fixed, paraffin-embedded human tonsil stained with CD5 antibody using peroxidase-conjugate and AEC chromogen. Note intense cell membrane staining of T cells.

product information

Product Type :

Antibody

Product Name :

CD5 Monoclonal Antibody (4C7)

Catalog # :

MA5-13308

Quantity :

500 µL

Price :

US 446.00

Clonality :

Monoclonal

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 1:2, Immunohistochemistry (Paraffin): 1:20-1:40, Western Blot: 1:10-1:200

Species :

Human

Clone :

4C7

Isotype :

IgG1, kappa

Storage :

4° C

Description :

CD5 is a 67 kDa human T-lymphocyte single-chain transmembrane glycoprotein. CD5 is present on all mature T-lymphocytes, on most of thymocytes and on many T-cell leukemias and lymphomas. CD5 also reacts with a subpopulation of activated B-cells and may act as a receptor in regulating T-cell proliferation. CD5 is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. CD5 is expressed by many T cell leukemia, lymphomas, and activated T cells. Diseases associated with CD5 dysfunction include thymus cancer and Richter's Syndrome.

Immunogen :

Recombinant protein corresponding to the external domain of the CD5 molecule

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:2, Immunohistochemistry (Paraffin): 1:20-1:40, Western Blot: 1:10-1:200

Aliases :

alanyl (membrane) aminopeptidase; alanyl aminopeptidase; alanyl aminopeptidase, membrane; aminopeptidase M; Aminopeptidase N; ANPEP; AP-M; APN; AP-N; CD antigen CD5; CD13; CD28; CD28 antigen (Tp44); CD28 molecule; Cd5; CD5 antigen; CD5 antigen (p56 62); CD5 antigen (p56-62); CD5 antigen p56-62; CD5 molecule; CD5 protein; CD74 antigen, invariant polypeptide of major; cell surface protein; costimulatory molecule B7 receptor CD28; fCD5; GP150; hAPN; LAP1; LEU1; Ly-1; Ly12; Ly-12; LyA; Ly-A; Lymphocyte antigen 1; Lymphocyte antigen CD5; lymphocyte antigen T1/Leu-1; Lyt-1; membrane alanyl aminopeptidase; microsomal aminopeptidase; Myeloid plasma membrane glycoprotein CD13; P150; Pan T cell; PEPN; T1; T-cell costimulatory molecule CD28; T-cell surface glycoprotein CD5; T-cell-specific surface glycoprotein CD28; unnamed protein product

more info or order :

Invitrogen product webpage