Chromogranin A Antibody Cocktail | Invitrogen MA5-13287 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Chromogranin A Antibody Cocktail

catalog :

MA5-13287

quantity :

500 µL

price :

US 389.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

LK2H10, PHE5

reactivity :

human

application :

immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 31

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; human; fig 1	Lu J, Adam B, Jack A, Lam A, Broad R, Chik C. Immune Cell Infiltrates in Pituitary Adenomas: More Macrophages in Larger Adenomas and More T Cells in Growth Hormone Adenomas. Endocr Pathol. 2015;26:263-72 pubmed publisher
immunohistochemistry; human; 1:800	Berruti A, Fazio N, Ferrero A, Brizzi M, Volante M, Nobili E, et al. Bevacizumab plus octreotide and metronomic capecitabine in patients with metastatic well-to-moderately differentiated neuroendocrine tumors: the XELBEVOCT study. BMC Cancer. 2014;14:184 pubmed publisher
immunohistochemistry; human; 1:800	Rapa I, Volante M, Migliore C, Farsetti A, Berruti A, Vittorio Scagliotti G, et al. Human ASH-1 promotes neuroendocrine differentiation in androgen deprivation conditions and interferes with androgen responsiveness in prostate cancer cells. Prostate. 2013;73:1241-9 pubmed publisher
immunohistochemistry; human; 1:4000	Hanna J, Reimann J, Haddad R, Krane J. Human papillomavirus-associated adenocarcinoma of the base of the tongue. Hum Pathol. 2013;44:1516-23 pubmed publisher
immunohistochemistry; human; 1:800	Volante M, Daniele L, Asioli S, Cassoni P, Comino A, Coverlizza S, et al. Tumor staging but not grading is associated with adverse clinical outcome in neuroendocrine tumors of the appendix: a retrospective clinical pathologic analysis of 138 cases. Am J Surg Pathol. 2013;37:606-12 pubmed publisher
immunohistochemistry; human; 1:800	Gündoğan M, Calli Demirkan N, Tekin K, Aybek H. Gastric histopathological findings and ghrelin expression in morbid obesity. Turk Patoloji Derg. 2013;29:19-26 pubmed publisher
immunohistochemistry; human; 1:200	Conconi D, Panzeri E, Redaelli S, Bovo G, Volante M, Viganò P, et al. DNA copy number alterations and PPARG amplification in a patient with multifocal bladder urothelial carcinoma. BMC Res Notes. 2012;5:607 pubmed publisher
immunohistochemistry; human	Haltas H, Bayrak R, Yenidunya S, Kosehan D, Sen M, Akin K. Invasive lobular carcinoma with extracellular mucin as a distinct variant of lobular carcinoma: a case report. Diagn Pathol. 2012;7:91 pubmed publisher
immunohistochemistry; human; 1:1000	Lawrence B, Kenney B, Svejda B, Schimmack S, Alaimo D, Barbieri A, et al. Comparison of PCR-based detection of chromogranin A mRNA with traditional histological lymph node staging of small intestinal neuroendocrine neoplasia. BMC Res Notes. 2012;5:318 pubmed publisher
immunohistochemistry; human; 1:800	Righi L, Rapa I, Votta A, Papotti M, Sapino A. Human achaete-scute homolog-1 expression in neuroendocrine breast carcinoma. Virchows Arch. 2012;460:415-21 pubmed publisher
immunohistochemistry; human; 1:4000	Kraft S, Faquin W, Krane J. HPV-associated neuroendocrine carcinoma of the oropharynx: a rare new entity with potentially aggressive clinical behavior. Am J Surg Pathol. 2012;36:321-30 pubmed publisher
immunohistochemistry; human; 1:2000	Giordano G, Pizzi S, Berretta R, D Adda T. A new case of primary signet-ring cell carcinoma of the cervix with prominent endometrial and myometrial involvement: Immunohistochemical and molecular studies and review of the literature. World J Surg Oncol. 2012;10:7 pubmed publisher
immunohistochemistry; human	Thai E, Leonardi F, Soliani P, Silini E. Late recurrence of a seminoma of the testis with a poorly differentiated neuroendocrine carcinoma component. Int J Surg Pathol. 2012;20:396-400 pubmed publisher
immunohistochemistry; human; 1:400	Sterlacci W, Fiegl M, Hilbe W, Auberger J, Mikuz G, Tzankov A. Clinical relevance of neuroendocrine differentiation in non-small cell lung cancer assessed by immunohistochemistry: a retrospective study on 405 surgically resected cases. Virchows Arch. 2009;455:125-32 pubmed publisher
immunohistochemistry; human; 1:2000	Inzani F, Rindi G, Tamborrino E, Cobelli R, Bordi C. Extra-adrenal composite paraganglioma with ganglioneuroma component presenting as a pancreatic mass. Endocr Pathol. 2009;20:191-5 pubmed publisher
immunohistochemistry; human	Vanni H, Kazeros A, Wang R, Harvey B, Ferris B, De B, et al. Cigarette smoking induces overexpression of a fat-depleting gene AZGP1 in the human. Chest. 2009;135:1197-1208 pubmed publisher
immunohistochemistry; human; 1:1000	Froio E, D Adda T, Fellegara G, Martella E, Caruana P, Pruneri G, et al. Uterine carcinosarcoma metastatic to the lung as large-cell neuroendocrine carcinoma with synchronous sarcoid granulomatosis. Lung Cancer. 2009;64:371-7 pubmed publisher
immunohistochemistry; human; 1:300	Mukhopadhyay S, El Zammar O, Katzenstein A. Pulmonary meningothelial-like nodules: new insights into a common but poorly understood entity. Am J Surg Pathol. 2009;33:487-95 pubmed publisher
immunohistochemistry; human; 1:1000	Fellegara G, D Adda T, Pilato F, Froio E, Ampollini L, Rusca M, et al. Genetics of a combined lung small cell carcinoma and large cell neuroendocrine carcinoma with adenocarcinoma. Virchows Arch. 2008;453:107-15 pubmed publisher
immunohistochemistry; human; 1:1000	Yaren A, Kelten C, Akbulut M, Teke Z, Duzcan E, Erdem E. Primary neuroendocrine carcinoma of the breast: a case report. Tumori. 2007;93:496-8 pubmed
immunohistochemistry; human; 1:1000	Froio E, D Adda T, Fellegara G, Ampollini L, Carbognani P, Rindi G. Three different synchronous primary lung tumours: a case report with extensive genetic analysis and review of the literature. Lung Cancer. 2008;59:395-402 pubmed
immunocytochemistry; human; 1:5000	Carolan B, Heguy A, Harvey B, Leopold P, Ferris B, Crystal R. Up-regulation of expression of the ubiquitin carboxyl-terminal hydrolase L1 gene in human airway epithelium of cigarette smokers. Cancer Res. 2006;66:10729-40 pubmed
immunohistochemistry; human	Dilbaz B, Bayoglu Y, Oral S, Cavusoglu D, Uluoglu O, Dilbaz S. Laparoscopic resection of urinary bladder paraganglioma: a case report. Surg Laparosc Endosc Percutan Tech. 2006;16:58-61 pubmed
immunohistochemistry; human; 1:100	Yilmazbayhan D, Ates L, Dilege S, Gulluoglu M, Tanju S, Kalayci G. Pulmonary large cell carcinoma with rhabdoid phenotype. Ann Diagn Pathol. 2005;9:223-6 pubmed
immunohistochemistry; human; 1:50	Erdogan G, Ozel E, Pestereli H, Salar Z, Tirak B, Karaveli S. Ovarian ependymoma. APMIS. 2005;113:301-3 pubmed
	Lee W. Mucinous cystadenoma of the pancreas with predominant stroma creating a solid tumor. World J Surg Oncol. 2005;3:59 pubmed
	Barbareschi M, Roldo C, Zamboni G, Capelli P, Cavazza A, Macri E, et al. CDX-2 homeobox gene product expression in neuroendocrine tumors: its role as a marker of intestinal neuroendocrine tumors. Am J Surg Pathol. 2004;28:1169-76 pubmed
	Deveci M, Deveci G. Altered distribution of metaplastic Paneth, gastrin and pancreatic acinar cells in atrophic gastritic mucosa with endocrine cell lesions. Tohoku J Exp Med. 2004;202:13-22 pubmed
	Papi G, Corrado S, Pomponi M, Carapezzi C, Cesinaro A, LiVolsi V. Concurrent lymph node metastases of medullary and papillary thyroid carcinoma in a case with RET oncogene germline mutation. Endocr Pathol. 2003;14:269-76 pubmed
	Ihtiyar E, Isiksoy S, Algin C, Sahin A, Erkasap S, Yasar B. Ectopic thyroid in the gallbladder: report of a case. Surg Today. 2003;33:777-80 pubmed
	van Eeden S, Quaedvlieg P, Taal B, Offerhaus G, Lamers C, van Velthuysen M. Classification of low-grade neuroendocrine tumors of midgut and unknown origin. Hum Pathol. 2002;33:1126-32 pubmed

image

image 1 :

Formalin-fixed, paraffin-embedded human carcinoid stained with Chromogranin A antibody using peroxidase-conjugate and DAB chromogen. Note cytoplasmic staining of tumor cells.

product information

Product Type :

Antibody

Product Name :

Chromogranin A Antibody Cocktail

Catalog # :

MA5-13287

Quantity :

500 µL

Price :

US 389.00

Clonality :

Cocktail

Purity :

Protein G

Host :

Mouse

Reactivity :

Human, Non-human primate

Applications :

Immunohistochemistry (Paraffin): 1:1,000

Species :

Human, Non-human primate

Clone :

LK2H10, PHE5

Isotype :

IgG1

Storage :

4° C

Description :

Chromogranin A (CHGA) is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocine cells. CHGA is a precursor to three biologically active peptides: vasostatin, pancreastatin, and parastatin. These peptides act as autocine or paracrine negative modulators of the neuroendocrine system. CHGA is an excellent marker for carcinoid tumors, pheo-chromocytomas, paragangliomas, and other neuro-endocrine tumors. Coexpression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms.

Immunogen :

Human pheochromocytoma

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1:1,000

Aliases :

AL-11; AL26; Beta-granin; betagranin (N-terminal fragment of chromogranin A); catestatin; CgA; CHGA; ChrA; chromofungin; chromogranin A; chromogranin A (parathyroid secretory protein 1); chromogranin A precursor; chromogranin-A; CTNNB; DKFZp686D02253; EA-92; ER-37; ES-43; FLJ25606; FLJ37923; GE-25; GR-44; GV-19; LF-19; LOW QUALITY PROTEIN: chromogranin-A; MGC105435; Pancreastatin; Parastatin; parathyroid secretory protein 1; p-Glu serpinin precursor; pituitary secretory protein I; Serpinin; Serpinin-RRG; SL21; SP-I; SS-18; Vasostatin I; Vasostatin II; Vasostatin-1; Vasostatin-2; WA-8; WE-14

more info or order :

Invitrogen product webpage