Published Application/Species/Sample/Dilution | Reference |
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- immunocytochemistry; human; 1:40; loading ...; fig 2a
| Samuel W, Jaworski C, Postnikova O, Kutty R, Duncan T, Tan L, et al. Appropriately differentiated ARPE-19 cells regain phenotype and gene expression profiles similar to those of native RPE cells. Mol Vis. 2017;23:60-89 pubmed
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- immunohistochemistry - frozen section; human; 1:150; loading ...; fig 1d
| Osterburg A, Nelson R, Yaniv B, Foot R, Donica W, Nashu M, et al. NK cell activating receptor ligand expression in lymphangioleiomyomatosis is associated with lung function decline. JCI Insight. 2016;1:e87270 pubmed publisher
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- immunocytochemistry; mouse; fig 3o
| Dennis M, Delevoye C, Acosta Ruiz A, Hurbain I, Romao M, Hesketh G, et al. BLOC-1 and BLOC-3 regulate VAMP7 cycling to and from melanosomes via distinct tubular transport carriers. J Cell Biol. 2016;214:293-308 pubmed publisher
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- immunohistochemistry - paraffin section; human; fig 1c
| Kemper K, Krijgsman O, Kong X, Cornelissen Steijger P, Shahrabi A, Weeber F, et al. BRAF(V600E) Kinase Domain Duplication Identified in Therapy-Refractory Melanoma Patient-Derived Xenografts. Cell Rep. 2016;16:263-277 pubmed publisher
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- immunohistochemistry; human; 1:80; fig 10
| Costache M, Dumitru A, Pătraşcu O, Popa Cherecheanu D, Bădilă P, Miu J, et al. A challenging case of ocular melanoma. Rom J Morphol Embryol. 2015;56:817-22 pubmed
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- flow cytometry; mouse; fig s1
| Dennis M, Mantegazza A, Snir O, Tenza D, Acosta Ruiz A, Delevoye C, et al. BLOC-2 targets recycling endosomal tubules to melanosomes for cargo delivery. J Cell Biol. 2015;209:563-77 pubmed publisher
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- immunohistochemistry - paraffin section; human; 1:80
| Costache M, Pătraşcu O, Dumitru A, Costache D, Voinea L, Simionescu O, et al. Histopathological findings concerning ocular melanomas. Rom J Morphol Embryol. 2014;55:649-53 pubmed
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| Abad S, Wieërs G, Colau D, Wildmann C, Delair E, Dhote R, et al. Absence of recognition of common melanocytic antigens by T cells isolated from the cerebrospinal fluid of a Vogt-Koyanagi-Harada patient. Mol Vis. 2014;20:956-69 pubmed
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- immunohistochemistry; human
| Jabbour M, Seoud M, Al Ahmadie H, Abdul Karim F, Zaatari G. ASPL-TFE3 translocation in vulvovaginal alveolar soft part sarcoma. Int J Gynecol Pathol. 2014;33:263-7 pubmed publisher
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- immunocytochemistry; human
- western blot; human
| Theos A, WATT B, Harper D, Janczura K, Theos S, Herman K, et al. The PKD domain distinguishes the trafficking and amyloidogenic properties of the pigment cell protein PMEL and its homologue GPNMB. Pigment Cell Melanoma Res. 2013;26:470-86 pubmed publisher
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- immunocytochemistry; human; 1:50
- western blot; human
| Leonhardt R, Vigneron N, Hee J, Graham M, Cresswell P. Critical residues in the PMEL/Pmel17 N-terminus direct the hierarchical assembly of melanosomal fibrils. Mol Biol Cell. 2013;24:964-81 pubmed publisher
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- immunohistochemistry; human; 1:100
| Kim B, Bae Y, Kim S, Jeong H, Hong S, Yoon S. Usefulness of Ki-67 (MIB-1) immunostaining in the diagnosis of pulmonary sclerosing hemangiomas. APMIS. 2013;121:105-10 pubmed publisher
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- immunohistochemistry - paraffin section; human; 1:40
| Niu H, Wang F, Zhang P, Bing Z. Cardiac Epithelioid PEComa: Report of Two Cases and Review of the Literature. Case Rep Med. 2012;2012:521678 pubmed publisher
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- immunohistochemistry; human; 1:40
| Wang Z, Gong Q, Fan Q. Expression of E-cadherin in angiomyolipoma. Hum Pathol. 2012;43:2348-53 pubmed publisher
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- immunohistochemistry; human
| Zhou Z, Yu M, Yang S, Zhou J, Sun R, Yang G. Dural angioleiomyoma of the middle cranial fossa: a case report and review of the literature. Brain Tumor Pathol. 2013;30:117-21 pubmed publisher
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- immunohistochemistry; human; 1:40
| Clayton E, Furth E, Ziober A, Xu T, Yao Y, Hwang P, et al. A case of primary clear cell hepatocellular carcinoma in a non-cirrhotic liver: an immunohistochemical and ultrastructural study. Rare Tumors. 2012;4:e29 pubmed publisher
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- immunohistochemistry; mouse; 1:1000
| Hooijkaas A, Gadiot J, van der Valk M, Mooi W, Blank C. Targeting BRAFV600E in an inducible murine model of melanoma. Am J Pathol. 2012;181:785-94 pubmed publisher
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- immunocytochemistry; mouse
| Sitaram A, Dennis M, Chaudhuri R, De Jesus Rojas W, Tenza D, Setty S, et al. Differential recognition of a dileucine-based sorting signal by AP-1 and AP-3 reveals a requirement for both BLOC-1 and AP-3 in delivery of OCA2 to melanosomes. Mol Biol Cell. 2012;23:3178-92 pubmed
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- immunohistochemistry; human; 1:200
| Duong T, Proulx S, Luciani P, Leroux J, Detmar M, Koopman P, et al. Genetic ablation of SOX18 function suppresses tumor lymphangiogenesis and metastasis of melanoma in mice. Cancer Res. 2012;72:3105-14 pubmed publisher
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- immunohistochemistry; human; 1:50
| Yin W, Li J, Chan J. Sporadic haemangioblastoma of the kidney with rhabdoid features and focal CD10 expression: report of a case and literature review. Diagn Pathol. 2012;7:39 pubmed publisher
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- immunohistochemistry; human
| Anbar T, El Sawy A, Attia S, Barakat M, Moftah N, El Ammawy T, et al. Effect of PUVA therapy on melanocytes and keratinocytes in non-segmental vitiligo: histopathological, immuno-histochemical and ultrastructural study. Photodermatol Photoimmunol Photomed. 2012;28:17-25 pubmed publisher
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| WATT B, Tenza D, Lemmon M, Kerje S, Raposo G, Andersson L, et al. Mutations in or near the transmembrane domain alter PMEL amyloid formation from functional to pathogenic. PLoS Genet. 2011;7:e1002286 pubmed publisher
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- immunocytochemistry; mouse
- western blot; mouse
| Hellström A, WATT B, Fard S, Tenza D, Mannstrom P, Narfstrom K, et al. Inactivation of Pmel alters melanosome shape but has only a subtle effect on visible pigmentation. PLoS Genet. 2011;7:e1002285 pubmed publisher
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- immunocytochemistry; human; 1:300
| Westbroek W, Klar A, Cullinane A, Ziegler S, Hurvitz H, Ganem A, et al. Cellular and clinical report of new Griscelli syndrome type III cases. Pigment Cell Melanoma Res. 2012;25:47-56 pubmed publisher
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- immunohistochemistry; human; 1:100
| Jabbour M, Fedda F, Tawil A, Shabb N, Boulos F. Follicular dendritic cell sarcoma of the head and neck expressing thyroid transcription factor-1: a case report with clinicopathologic and immunohistochemical literature review. Appl Immunohistochem Mol Morphol. 2014;22:705-12 pubmed publisher
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- immunocytochemistry; human; 1:100
- western blot; mouse
| Beaumont K, Hamilton N, Moores M, Brown D, Ohbayashi N, Cairncross O, et al. The recycling endosome protein Rab17 regulates melanocytic filopodia formation and melanosome trafficking. Traffic. 2011;12:627-43 pubmed publisher
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- immunocytochemistry; human; fig 3
- western blot; human; fig 1
| Leonhardt R, Vigneron N, Rahner C, Cresswell P. Proprotein convertases process Pmel17 during secretion. J Biol Chem. 2011;286:9321-37 pubmed publisher
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- immunohistochemistry; human; 1:150
| Clay M, Gibson P, Lowell J, Cooper K. Microscopic uterine lymphangioleiomyomatosis perivascular epithelioid cell neoplasm: a case report with the earliest manifestation of this enigmatic neoplasm. Int J Gynecol Pathol. 2011;30:71-5 pubmed publisher
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- immunohistochemistry; human; 1:100
| Yu G, Qu G, Kong L, Pan X, Wang W, Lv J. Primary myoepithelial carcinoma of the larynx: case report and review of the literature. Pathol Res Pract. 2011;207:127-30 pubmed publisher
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- immunocytochemistry; human; 1:800
| Bean S, Baker A, Eloubeidi M, Eltoum I, Jhala N, Crowe R, et al. Endoscopic ultrasound-guided fine-needle aspiration of intrathoracic and intra-abdominal spindle cell and mesenchymal lesions. Cancer Cytopathol. 2011;119:37-48 pubmed publisher
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- immunocytochemistry; human; 1:200
| Huizing M, Pederson B, Hess R, Griffin A, Helip Wooley A, Westbroek W, et al. Clinical and cellular characterisation of Hermansky-Pudlak syndrome type 6. J Med Genet. 2009;46:803-10 pubmed publisher
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- immunocytochemistry; human
- western blot; human
| WATT B, van Niel G, Fowler D, Hurbain I, Luk K, Stayrook S, et al. N-terminal domains elicit formation of functional Pmel17 amyloid fibrils. J Biol Chem. 2009;284:35543-55 pubmed publisher
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- immunocytochemistry; mouse
| Truschel S, Simoes S, Setty S, Harper D, Tenza D, Thomas P, et al. ESCRT-I function is required for Tyrp1 transport from early endosomes to the melanosome limiting membrane. Traffic. 2009;10:1318-36 pubmed publisher
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- immunohistochemistry; human
| Zurac S, Andrei R, Petsakos G, Nichita L, Bastian A, Micu G, et al. Cutaneous metastases of malignant melanoma--how difficult can it be?. Rom J Intern Med. 2008;46:375-8 pubmed
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- immunohistochemistry; human
| Anbar T, El Sawy A, Attia S, Moftah N, El Tonsy M. Patterns of repigmentation in two cases of hypopigmented type of vitiligo. Photodermatol Photoimmunol Photomed. 2009;25:156-8 pubmed publisher
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- immunohistochemistry; human
| Mukhopadhyay S, El Zammar O, Katzenstein A. Pulmonary meningothelial-like nodules: new insights into a common but poorly understood entity. Am J Surg Pathol. 2009;33:487-95 pubmed publisher
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- immunohistochemistry; human
| Fadare O, Liang S. Epithelioid smooth muscle tumors of the uterus do not express CD1a: a potential immunohistochemical adjunct in their distinction from uterine perivascular epithelioid cell tumors. Ann Diagn Pathol. 2008;12:401-5 pubmed publisher
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| Setty S, Tenza D, Sviderskaya E, Bennett D, Raposo G, Marks M. Cell-specific ATP7A transport sustains copper-dependent tyrosinase activity in melanosomes. Nature. 2008;454:1142-6 pubmed publisher
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- immunohistochemistry; mouse
| Tabata H, Kawamura N, Sun Wada G, Wada Y. Vacuolar-type H(+)-ATPase with the a3 isoform is the proton pump on premature melanosomes. Cell Tissue Res. 2008;332:447-60 pubmed publisher
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- immunocytochemistry; human; 1:100
| Westbroek W, Tuchman M, Tinloy B, De Wever O, Vilboux T, Hertz J, et al. A novel missense mutation (G43S) in the switch I region of Rab27A causing Griscelli syndrome. Mol Genet Metab. 2008;94:248-54 pubmed publisher
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- immunocytochemistry; mouse
- western blot; mouse
| Groux Degroote S, van Dijk S, Wolthoorn J, Neumann S, Theos A, De Mazière A, et al. Glycolipid-dependent sorting of melanosomal from lysosomal membrane proteins by lumenal determinants. Traffic. 2008;9:951-63 pubmed publisher
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- western blot; human; 1:500
| Roberts D, Newton R, Leonard J, Sturm R. Melanocytes expressing MC1R polymorphisms associated with red hair color have altered MSH-ligand activated pigmentary responses in coculture with keratinocytes. J Cell Physiol. 2008;215:344-55 pubmed
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- immunohistochemistry; bovine
| Oruc E. Melanosis in a Holstein heifer. J Vet Med A Physiol Pathol Clin Med. 2007;54:501-3 pubmed
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| Kawakami A, Sakane F, Imai S, Yasuda S, Kai M, Kanoh H, et al. Rab7 regulates maturation of melanosomal matrix protein gp100/Pmel17/Silv. J Invest Dermatol. 2008;128:143-50 pubmed
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- immunohistochemistry; human
| Westbroek W, Adams D, Huizing M, Koshoffer A, Dorward H, Tinloy B, et al. Cellular defects in Chediak-Higashi syndrome correlate with the molecular genotype and clinical phenotype. J Invest Dermatol. 2007;127:2674-7 pubmed
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- immunocytochemistry; human; 1:200
| Helip Wooley A, Westbroek W, Dorward H, Koshoffer A, Huizing M, Boissy R, et al. Improper trafficking of melanocyte-specific proteins in Hermansky-Pudlak syndrome type-5. J Invest Dermatol. 2007;127:1471-8 pubmed
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- immunohistochemistry; human
| Pecciarini L, Cangi M, Lo Cunsolo C, Macri E, Dal Cin E, Martignoni G, et al. Characterization of t(6;11)(p21;q12) in a renal-cell carcinoma of an adult patient. Genes Chromosomes Cancer. 2007;46:419-26 pubmed
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| Zhang J, Eguchi J, Kruse C, Gomez G, Fakhrai H, Schroter S, et al. Antigenic profiling of glioma cells to generate allogeneic vaccines or dendritic cell-based therapeutics. Clin Cancer Res. 2007;13:566-575 pubmed publisher
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- immunocytochemistry; mouse
- flow cytometry; human
- immunocytochemistry; human
- western blot; human
| Setty S, Tenza D, Truschel S, Chou E, Sviderskaya E, Theos A, et al. BLOC-1 is required for cargo-specific sorting from vacuolar early endosomes toward lysosome-related organelles. Mol Biol Cell. 2007;18:768-80 pubmed
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- immunocytochemistry; human
- western blot; human
| Theos A, Berson J, Theos S, Herman K, Harper D, Tenza D, et al. Dual loss of ER export and endocytic signals with altered melanosome morphology in the silver mutation of Pmel17. Mol Biol Cell. 2006;17:3598-612 pubmed
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- immunohistochemistry; human
| Wankowicz Kalinska A, Mailliard R, Olson K, Graham F, Edington H, Kirkwood J, et al. Accumulation of low-avidity anti-melanocortin receptor 1 (anti-MC1R) CD8+ T cells in the lesional skin of a patient with melanoma-related depigmentation. Melanoma Res. 2006;16:165-74 pubmed
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| Matafora V, Farris F, Restuccia U, Tamburri S, Martano G, Bernardelli C, et al. Amyloid aggregates accumulate in melanoma metastasis modulating YAP activity. EMBO Rep. 2020;21:e50446 pubmed publisher
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| Zhang Z, Gong J, Sviderskaya E, Wei A, Li W. Mitochondrial NCKX5 regulates melanosomal biogenesis and pigment production. J Cell Sci. 2019;: pubmed publisher
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| Li Z, Wang C, Deng H, Wu J, Huang H, Sun R, et al. Robust Photodynamic Therapy Using 5-ALA-Incorporated Nanocomplexes Cures Metastatic Melanoma through Priming of CD4+CD8+ Double Positive T Cells. Adv Sci (Weinh). 2019;6:1802057 pubmed publisher
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| Ozaki Y, Shindoh J, Miura Y, Nakajima H, Oki R, Uchiyama M, et al. Serial pseudoprogression of metastatic malignant melanoma in a patient treated with nivolumab: a case report. BMC Cancer. 2017;17:778 pubmed publisher
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| Ling Y, Gong Q, Xiong X, Sun L, Zhao W, Zhu W, et al. Protective effect of madecassoside on H2O2-induced oxidative stress and autophagy activation in human melanocytes. Oncotarget. 2017;8:51066-51075 pubmed publisher
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| Yu W, Wang Y, Jiang Y, Zhang W, Li Y. Distinct immunophenotypes and prognostic factors in renal cell carcinoma with sarcomatoid differentiation: a systematic study of 19 immunohistochemical markers in 42 cases. BMC Cancer. 2017;17:293 pubmed publisher
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| Liu G, Ying H, Zeng G, Wheeler C, Black K, Yu J. HER-2, gp100, and MAGE-1 are expressed in human glioblastoma and recognized by cytotoxic T cells. Cancer Res. 2004;64:4980-6 pubmed
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| Ramakrishna V, Treml J, Vitale L, Connolly J, O Neill T, Smith P, et al. Mannose receptor targeting of tumor antigen pmel17 to human dendritic cells directs anti-melanoma T cell responses via multiple HLA molecules. J Immunol. 2004;172:2845-52 pubmed
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| Berson J, Theos A, Harper D, Tenza D, Raposo G, Marks M. Proprotein convertase cleavage liberates a fibrillogenic fragment of a resident glycoprotein to initiate melanosome biogenesis. J Cell Biol. 2003;161:521-33 pubmed
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