Cytokeratin Pan Antibody Cocktail | Invitrogen MA5-13203 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Cytokeratin Pan Antibody Cocktail

catalog :

MA5-13203

quantity :

500 µL

price :

US 342

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

PAN-CK

reactivity :

Japanese rice fish, human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 37

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; loading ...; fig s1b	Aprile F, Källstig E, Limorenko G, Vendruscolo M, Ron D, Hansen C. The molecular chaperones DNAJB6 and Hsp70 cooperate to suppress α-synuclein aggregation. Sci Rep. 2017;7:9039 pubmed publisher
immunocytochemistry; mouse; loading ...; fig 3c western blot; mouse; loading ...; fig 3d	Berens E, Sharif G, Schmidt M, Yan G, Shuptrine C, Weiner L, et al. Keratin-associated protein 5-5 controls cytoskeletal function and cancer cell vascular invasion. Oncogene. 2017;36:593-605 pubmed publisher
immunohistochemistry - paraffin section; mouse; fig 4	Gao L, Jiang Y, Mu L, Liu Y, Wang F, Wang P, et al. Efficient Generation of Mice with Consistent Transgene Expression by FEEST. Sci Rep. 2015;5:16284 pubmed publisher
western blot; human	Katanov C, Lerrer S, Liubomirski Y, Leider Trejo L, Meshel T, Bar J, et al. Regulation of the inflammatory profile of stromal cells in human breast cancer: prominent roles for TNF-? and the NF-?B pathway. Stem Cell Res Ther. 2015;6:87 pubmed publisher
immunohistochemistry; human; 1:100	Akbulut M, Gunhan Bilgen I, Zekioglu O, Duygulu G, Oktay A, Ozdemir N. Fine needle aspiration cytology of inflammatory myofibroblastic tumour (inflammatory pseudotumour) of the breast: a case report and review of the literature. Cytopathology. 2007;18:384-7 pubmed
immunohistochemistry; human; 1:50	Yorulmaz G, Erdogan G, Pestereli H, Savas B, Karaveli F. Epithelioid leiomyosarcoma with rhabdoid features. Wien Klin Wochenschr. 2007;119:557-60 pubmed
immunohistochemistry; human; 1:50	Elpek G, Küpesiz G, Ogus M. Incidental calcifying fibrous tumor of the stomach presenting as a polyp. Pathol Int. 2006;56:227-31 pubmed
immunocytochemistry; Japanese rice fish; 1:500	Chi S, Wu Y, Cheng T. Persistent infection of betanodavirus in a novel cell line derived from the brain tissue of barramundi Lates calcarifer. Dis Aquat Organ. 2005;65:91-8 pubmed
immunohistochemistry; human	Atinkaya C, Ozlem Küçük N, Koparal H, Aras G, Sak S, Ozdemir N. Mediastinal intraoperative radioisotope sentinel lymph node mapping in non-small-cell lung cancer. Nucl Med Commun. 2005;26:717-20 pubmed
immunohistochemistry; human; 1:50	Erdogan G, Ozel E, Pestereli H, Salar Z, Tirak B, Karaveli S. Ovarian ependymoma. APMIS. 2005;113:301-3 pubmed
	Kapeleris J, M xfc ller Bark J, Ranjit S, Richard D, Vela I, O Byrne K, et al. Modelling reoxygenation effects in non-small cell lung cancer cell lines and showing epithelial-mesenchymal transition. J Cancer Res Clin Oncol. 2022;148:3501-3510 pubmed publisher
	Savio M, Ferraresi A, Corpina C, Vandenberghe S, Scarlata C, Sottile V, et al. Resveratrol and Its Analogue 4,4'-Dihydroxy-trans-stilbene Inhibit Lewis Lung Carcinoma Growth In Vivo through Apoptosis, Autophagy and Modulation of the Tumour Microenvironment in a Murine Model. Biomedicines. 2022;10: pubmed publisher
	Li X, Dean D, Ferreira A, Nelson S, Hornicek F, Yu S, et al. Establishment and Characterization of a Novel Dedifferentiated Chondrosarcoma Cell Line DDCS2. Cancer Control. 2021;28:10732748211045274 pubmed publisher
	Yang S, Li H, Yao H, Zhang Y, Bao H, Wu L, et al. Long noncoding RNA ERLR mediates epithelial-mesenchymal transition of retinal pigment epithelial cells and promotes experimental proliferative vitreoretinopathy. Cell Death Differ. 2021;28:2351-2366 pubmed publisher
	Alowaysi M, Astro V, Fiacco E, Alzahrani F, Alkuraya F, Adamo A. Generation of iPSC lines (KAUSTi011-A, KAUSTi011-B) from a Saudi patient with epileptic encephalopathy carrying homozygous mutation in the GLP1R gene. Stem Cell Res. 2020;50:102148 pubmed publisher
	Alowaysi M, Fiacco E, Astro V, Adamo A. Generation of two iPSC lines (KAUSTi001-A, KAUSTi002-A) from a rare high-grade Klinefelter Syndrome patient (49-XXXXY) carrying a balanced translocation t(4,11) (q35,q23). Stem Cell Res. 2020;49:102098 pubmed publisher
	Fiacco E, Alowaysi M, Astro V, Adamo A. Derivation of two naturally isogenic iPSC lines (KAUSTi006-A and KAUSTi006-B) from a mosaic Klinefelter Syndrome patient (47-XXY/46-XY). Stem Cell Res. 2020;49:102049 pubmed publisher
	Alowaysi M, Fiacco E, Astro V, Adamo A. Establishment of an iPSC cohort from three unrelated 47-XXY Klinefelter Syndrome patients (KAUSTi007-A, KAUSTi007-B, KAUSTi009-A, KAUSTi009-B, KAUSTi010-A, KAUSTi010-B). Stem Cell Res. 2020;49:102042 pubmed publisher
	Alowaysi M, Fiacco E, Astro V, Adamo A. Establishment of iPSC lines from a high-grade Klinefelter Syndrome patient (49-XXXXY) and two genetically matched healthy relatives (KAUSTi003-A, KAUSTi004-A, KAUSTi004-B, KAUSTi005-A, KAUSTi005-B, KAUSTi005-C). Stem Cell Res. 2020;49:102008 pubmed publisher
	Yong C, Moose D, Bannick N, Gutierrez W, Vanneste M, Svensson R, et al. Locally invasive, castrate-resistant prostate cancer in a Pten/Trp53 double knockout mouse model of prostate cancer monitored with non-invasive bioluminescent imaging. PLoS ONE. 2020;15:e0232807 pubmed publisher
	Grigore F, Yang H, Hanson N, VanBrocklin M, Sarver A, Robinson J. BRAF inhibition in melanoma is associated with the dysregulation of histone methylation and histone methyltransferases. Neoplasia. 2020;22:376-389 pubmed publisher
	Pozdeyev N, Erickson T, Zhang L, Ellison K, Rivard C, Sams S, et al. Comprehensive Immune Profiling of Medullary Thyroid Cancer. Thyroid. 2020;30:1263-1279 pubmed publisher
	Vossaert L, Wang Q, Salman R, McCombs A, Patel V, Qu C, et al. Validation Studies for Single Circulating Trophoblast Genetic Testing as a Form of Noninvasive Prenatal Diagnosis. Am J Hum Genet. 2019;105:1262-1273 pubmed publisher
	Steinmann S, Kunze P, Hampel C, Eckstein M, Bertram Bramsen J, Muenzner J, et al. DAPK1 loss triggers tumor invasion in colorectal tumor cells. Cell Death Dis. 2019;10:895 pubmed publisher
	Hu J, Ishihara M, Chin A, Wu L. Establishment of xenografts of urological cancers on chicken chorioallantoic membrane (CAM) to study metastasis. Precis Clin Med. 2019;2:140-151 pubmed publisher
	Moch M, Schwarz N, Windoffer R, Leube R. The keratin-desmosome scaffold: pivotal role of desmosomes for keratin network morphogenesis. Cell Mol Life Sci. 2019;: pubmed publisher
	Turano M, Costabile V, Cerasuolo A, Duraturo F, Liccardo R, Delrio P, et al. Characterisation of mesenchymal colon tumour-derived cells in tumourspheres as a model for colorectal cancer progression. Int J Oncol. 2018;53:2379-2396 pubmed publisher
	Zhang S, Choi H, Jung H, Lee J. FGF10 Is Required for Circumvallate Papilla Morphogenesis by Maintaining Lgr5 Activity. Front Physiol. 2018;9:1192 pubmed publisher
	Høye A, Tolstrup S, Horton E, Nicolau M, Frost H, Woo J, et al. Tumor endothelial marker 8 promotes cancer progression and metastasis. Oncotarget. 2018;9:30173-30188 pubmed publisher
	Wu T, Xu K, Martinek J, Young R, Banchereau R, George J, et al. IL1 Receptor Antagonist Controls Transcriptional Signature of Inflammation in Patients with Metastatic Breast Cancer. Cancer Res. 2018;78:5243-5258 pubmed publisher
	Wan Y, Kang G, Sreenivasan C, Daharsh L, Zhang J, Fan W, et al. A DNA Vaccine Expressing Consensus Hemagglutinin-Esterase Fusion Protein Protected Guinea Pigs from Infection by Two Lineages of Influenza D Virus. J Virol. 2018;92: pubmed publisher
	Sheng Y, Wang T, Li H, Zhang Z, Chen J, He C, et al. Comparison of analytic performances of Cellsearch and iFISH approach in detecting circulating tumor cells. Oncotarget. 2017;8:8801-8806 pubmed publisher
	Anderson P, Lynch T, Engelhardt J. Multipotent Myoepithelial Progenitor Cells Are Born Early during Airway Submucosal Gland Development. Am J Respir Cell Mol Biol. 2017;56:716-726 pubmed publisher
	Li X, Nadauld L, Ootani A, Corney D, Pai R, Gevaert O, et al. Oncogenic transformation of diverse gastrointestinal tissues in primary organoid culture. Nat Med. 2014;20:769-77 pubmed publisher
	Kim J, Sun C, Jeon S, You Y, Shin J, Lee S, et al. Glucocorticoid treatment independently affects expansion and transdifferentiation of porcine neonatal pancreas cell clusters. BMB Rep. 2012;45:51-6 pubmed
	Dhar R, Karmakar S, Sriraman R, Talwar G, Das C. Efficacy of a recombinant chimeric anti-hCG antibody to prevent human cytotrophoblasts fusion and block progesterone synthesis. Am J Reprod Immunol. 2004;51:358-63 pubmed
	Sashiyama H, Shino Y, Sakao S, Shimada H, Kobayashi S, Ochiai T, et al. Alteration of integrin expression relates to malignant progression of human papillomavirus-immortalized esophageal keratinocytes. Cancer Lett. 2002;177:21-8 pubmed

image

image 1 :

Formalin-fixed, paraffin-embedded human skin stained with Keratin, Pan antibody using peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of epidermis.

product information

Product Type :

Antibody

Product Name :

Cytokeratin Pan Antibody Cocktail

Catalog # :

MA5-13203

Quantity :

500 µL

Price :

US 342

Clonality :

Cocktail

Purity :

Protein A/G

Host :

Mouse

Reactivity :

Human, Mouse

Applications :

Immunocytochemistry: 1:20-1:200, Immunohistochemistry (Paraffin): 1-2 µg/mL, Western Blot: 1:1,000-1:5,000

Species :

Human, Mouse

Clone :

PAN-CK

Isotype :

IgG

Storage :

4° C

Description :

Cytokeratin pan is part of a subfamily of intermediate filament proteins that are characterized by remarkable biochemical diversity, and represented in human epithelial tissues by at least 20 different polypeptides. Cytokeratins range in molecular weight between 40 kDa- 68 kDa, and an isoelectric pH between 4.9-7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays. The composition of cytokeratin pairs vary with the epithelial cell type, stage of differentiation, cellular growth environment, and disease state. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:20-1:200, Immunohistochemistry (Paraffin): 1-2 µg/mL, Western Blot: 1:1,000-1:5,000

Aliases :

2310016L08Rik; 3300001P10Rik; 39.1; 40-kDa keratin intermediate filament; 47 kDa cytokeratin; 56 kDa cytokeratin; 57kd keratin; 57kDa keratin; 58 kDa cytokeratin; 60-kDa keratin; 63kDa Keratin; 65 kDa cytokeratin; 67 kDa cytokeratin; AA960620; adult keratin; AI324768; AI528832; AI626930; AI663979; AL022697; alpha keratin; AU019895; AW108092; AW146334; basic epidermal type II cytokeratin (carboxy-terminal region, clone pUF164); BB005427; BCIE; BIE; Card2; cell proliferation-inducing gene 46 protein; CK 2e; CK1; CK-1; CK10; CK-10; CK13; CK-13; CK14; CK-14; CK15; CK-15; CK16; CK-16; CK-17; CK18; CK-18; CK19; CK-19; CK-1B; CK-2e; CK3; CK-3; CK4; CK-4; CK5; CK-5; ck55; CK6A; CK-6A; CK6C; CK-6C; CK6D; CK-6D; CK-6E; CK7; CK-7; CK8; CK-8; CYK18; CYK4; CYK8; CYKER; cytokeratin 1; cytokeratin 10; cytokeratin 13; cytokeratin 14; cytokeratin 15; cytokeratin 16; cytokeratin 18; cytokeratin 19; cytokeratin 3; cytokeratin 4; cytokeratin 5; cytokeratin 6A; cytokeratin 6C; cytokeratin 6D; cytokeratin 7; cytokeratin 8; cytokeratin 8 (370 AA); cytokeratin endo A; Cytokeratin endo B; cytokeratin otokeratin; cytokeratin type II; cytokeratin type II, component Ib/c; cytokeratin type II, component III; cytokeratin VIB; cytokeratin VII; cytokeratin-1; Cytokeratin-10; cytokeratin-13; Cytokeratin-14; cytokeratin-15; Cytokeratin-16; cytokeratin-17; Cytokeratin-18; cytokeratin-19; Cytokeratin-1B; Cytokeratin-2e; cytokeratin-3; Cytokeratin-4; cytokeratin-5; Cytokeratin-6A; cytokeratin-6B; cytokeratin-6C; Cytokeratin-6D; cytokeratin-6E; cytokeratin-7; Cytokeratin-8; cytokeratin-A; Cytoskeletal 57 kDa keratin; D130054E02Rik; D15Wsu77e; DDD; DDD1; ear specific cytokeratin; EBS2; ebs3; ebs4; EGK_03684; EGK_03685; EHK; EHK1; Endo B; EndoA; EndoC; epidermal keratin 10; epidermal keratin VII; epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types; epidermolysis bullosa simplex, Dowling-Meara, Koebner; epidermolytic hyperkeratosis 1; epidermolytic hyperkeratosis; keratosis palmaris et plantaris; epithelial keratin 1; epithelial keratin 10; epithelial keratin 2e; Epithelial keratin-1; Epithelial keratin-2e; EPPK; fgk; fin and gill keratin; FNEPPK; focal non-epidermolytic palmoplantar keratoderma; GK-19; Hair alpha protein; HMWCK; Hom s 5; I79_019823; I79_021074; I79_023185; I79_024335; intermediate filament protein; K1; K10; K13; K14; K15; K16; K17; K18; K19; K1B; K1C1; K1CO; K1CP; K1CS; K2C7; K2C8; K2e; K3; K3 keratin; K4; K5; K6A; K6a keratin; K6C; K6D; K7; K77; K8; Ka10; Ka13; Ka14; Ka15; Ka16; Ka17; Ka19; kamp-keratin derived antimicrobial peptide; Kb1; Kb2; Kb4; Kb7; KDAMP; KER1; Ker10; Ker2; KERA; keratin; keratin 1; keratin 1 (epidermolytic hyperkeratosis); keratin 1, type II; keratin 10; keratin 10 (epidermolytic hyperkeratosis); keratin 10 (epidermolytic hyperkeratosis; keratosis palmaris et plantaris); keratin 10, type I; keratin 10, type I L homeolog; keratin 10, type I S homeolog; keratin 12, gene 2 S homeolog; keratin 13; keratin 13, type I; keratin 13, type I S homeolog; keratin 14; keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner); keratin 14, type I; keratin 14, type I L homeolog; keratin 15; keratin 15, gene 1 S homeolog; keratin 15, type I; keratin 16; keratin 16 (focal non-epidermolytic palmoplantar keratoderma); keratin 16, type I; keratin 16, type I S homeolog; keratin 17; keratin 17 L homeolog; keratin 17, type I; keratin 17, type I L homeolog; keratin 18; keratin 18, type I; keratin 19; keratin 19 S homeolog; keratin 19 S homeolog; keratin 19; keratin 19, type I; Keratin 1B; keratin 2; keratin 2 (epidermal ichthyosis bullosa of Siemens); keratin 2 epidermis; keratin 2, type II; keratin 24; keratin 2A; keratin 2A (epidermal ichthyosis bullosa of Siemens); keratin 3; keratin 3, type II; keratin 4; keratin 4, type II; keratin 5; keratin 5 (epidermolysis bullosa simplex Dowling-Meara/Kobner/Weber-Cockayne types); keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types)

more info or order :

Invitrogen product webpage