CD31 Monoclonal Antibody (JC/70A) | Invitrogen MA5-13188 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD31 Monoclonal Antibody (JC/70A)

catalog :

MA5-13188

quantity :

500 µL

price :

US 426

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

JC/70A

reactivity :

human, mouse, rat, domestic rabbit, rhesus macaque

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 91

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 8f	Chen X, Miao M, Zhou M, Chen J, Li D, Zhang L, et al. Poly-L-arginine promotes asthma angiogenesis through induction of FGFBP1 in airway epithelial cells via activation of the mTORC1-STAT3 pathway. Cell Death Dis. 2021;12:761 pubmed publisher
immunohistochemistry - paraffin section; human; 1:300; fig s5	Loayza Puch F, Rooijers K, Buil L, Zijlstra J, Oude Vrielink J, Lopes R, et al. Tumour-specific proline vulnerability uncovered by differential ribosome codon reading. Nature. 2016;530:490-4 pubmed publisher
immunohistochemistry; human; 1:100; fig 1	Wang T, Cunningham A, HOUSTON K, Sharma A, Chen L, Dokun A, et al. Endothelial interleukin-21 receptor up-regulation in peripheral artery disease. Vasc Med. 2016;21:99-104 pubmed publisher
immunohistochemistry; human; 1:50; fig 3	El Gendi S, Abdelzaher E, Mostafa M, Sheasha G. FGF18 as a potential biomarker in serous and mucinous ovarian tumors. Tumour Biol. 2016;37:3173-83 pubmed publisher
flow cytometry; rat; 1:1000; fig 6	El Sadik A, El Ghamrawy T, Abd El Galil T. The Effect of Mesenchymal Stem Cells and Chitosan Gel on Full Thickness Skin Wound Healing in Albino Rats: Histological, Immunohistochemical and Fluorescent Study. PLoS ONE. 2015;10:e0137544 pubmed publisher
immunohistochemistry - paraffin section; human; fig 1f	Carpenter R, Paw I, Zhu H, Sirkisoon S, Xing F, Watabe K, et al. The gain-of-function GLI1 transcription factor TGLI1 enhances expression of VEGF-C and TEM7 to promote glioblastoma angiogenesis. Oncotarget. 2015;6:22653-65 pubmed
immunohistochemistry - paraffin section; human; 1:25	Gurzu S, Kádár Z, Sugimura H, Bara T, Hălmaciu I, Jung I. Gastric cancer in young vs old Romanian patients: immunoprofile with emphasis on maspin and mena protein reactivity. APMIS. 2015;123:223-33 pubmed publisher
immunohistochemistry; human; 1:50	Gurzu S, Ciortea D, Tamasi A, Golea M, Bodi A, Sahlean D, et al. The immunohistochemical profile of granular cell (Abrikossoff) tumor suggests an endomesenchymal origin. Arch Dermatol Res. 2015;307:151-7 pubmed publisher
immunohistochemistry; rat; 1:30	Kaygusuz I, Eser A, Inegöl Gümüş I, Köşüş A, Yenidunya S, Namuslu M, et al. Effect of anti-vascular endothelial growth factor antibody during early fetal development in rats. J Matern Fetal Neonatal Med. 2014;27:1744-8 pubmed publisher
immunohistochemistry - paraffin section; human; 1:200	Luo W, Yao K. Cancer stem cell characteristics, ALDH1 expression in the invasive front of nasopharyngeal carcinoma. Virchows Arch. 2014;464:35-43 pubmed publisher
immunohistochemistry; human	Ceyhan L, Cağrı Savaş M, Baspinar S, Duman L, Büyükyavuz B. The correlation between preputial blood flow and microvessel density in distal hypospadias: a prospective clinical study. J Pediatr Urol. 2014;10:103-6 pubmed publisher
immunohistochemistry - paraffin section; human; 1:40	Erdem H, Kayikci M, Oktay M, Uzunlar A, Tekin A, Sener E, et al. Mast cells numbers and peritumoral microvessel density of the prostatic adenocarcinomas and correlation with prognostic parameters. Med Glas (Zenica). 2013;10:293-7 pubmed
immunohistochemistry - paraffin section; human; 1:250	Fischer M, Wimmer I, Hoftberger R, Gerlach S, Haider L, Zrzavy T, et al. Disease-specific molecular events in cortical multiple sclerosis lesions. Brain. 2013;136:1799-815 pubmed publisher
immunohistochemistry; human; 1:50	Bartoloni G, Pucci A, Giorlandino A, Berretta M, Mignosa C, Italia F, et al. Incidental Epstein-Barr virus associated atypical lymphoid proliferation arising in a left atrial myxoma: a case of long survival without any postsurgical treatment and review of the literature. Cardiovasc Pathol. 2013;22:e5-10 pubmed publisher
immunohistochemistry; human	Zhou Z, Yu M, Yang S, Zhou J, Sun R, Yang G. Dural angioleiomyoma of the middle cranial fossa: a case report and review of the literature. Brain Tumor Pathol. 2013;30:117-21 pubmed publisher
immunohistochemistry; human; 1:50	Kandemir N, Barut F, Gun B, Tekin N, Keser S, Ozdamar S. Histopathological analysis of vesicular and bullous lesions in Kaposi sarcoma. Diagn Pathol. 2012;7:101 pubmed publisher
immunohistochemistry; human; 1:30	Li C, Chen Y, Zhang H, Zheng X, Wang J. Epithelioid angiosarcoma arising in schwannoma: report of three Chinese cases with review of the literature. Pathol Int. 2012;62:500-5 pubmed publisher
immunohistochemistry; human; 1:70	Minsart A, Ntoutoume Sima F, Vandenhoute K, Jani J, Van Pachterbeke C. Does three-dimensional power Doppler ultrasound predict histopathological findings of uterine fibroids? A preliminary study. Ultrasound Obstet Gynecol. 2012;40:714-20 pubmed publisher
immunohistochemistry; domestic rabbit; 1:500	Wang H, Zheng L, Feng Y, Xie X, Yang X, Zhang G. CTA combined with CT perfusion for assessing the efficacy of anti-angiogenic therapy in rabbit VX2 tumors. Acad Radiol. 2012;19:358-65 pubmed publisher
immunohistochemistry; human; 1:100	Noguchi K, Miwa Y, Sunohara M, Sato I. Analysis of vascular distribution and growth factors in human gingival tissue associated with periodontal probing depth. Okajimas Folia Anat Jpn. 2011;88:75-83 pubmed
immunohistochemistry; mouse; 1:50	Zhao M, Tominaga Y, Ohuchida K, Mizumoto K, Cui L, Kozono S, et al. Significance of combination therapy of zoledronic acid and gemcitabine on pancreatic cancer. Cancer Sci. 2012;103:58-66 pubmed publisher
immunohistochemistry; rhesus macaque; 1:100	Nakayama K, Batchelder C, Lee C, Tarantal A. Renal tissue engineering with decellularized rhesus monkey kidneys: age-related differences. Tissue Eng Part A. 2011;17:2891-901 pubmed publisher
immunohistochemistry; human	Carrascosa C, Obula R, Missiaglia E, Lehr H, Delorenzi M, Frattini M, et al. MFG-E8/lactadherin regulates cyclins D1/D3 expression and enhances the tumorigenic potential of mammary epithelial cells. Oncogene. 2012;31:1521-32 pubmed publisher
immunohistochemistry; mouse; 1:100	Siamakpour Reihani S, CASTER J, Bandhu Nepal D, Courtwright A, Hilliard E, Usary J, et al. The role of calcineurin/NFAT in SFRP2 induced angiogenesis--a rationale for breast cancer treatment with the calcineurin inhibitor tacrolimus. PLoS ONE. 2011;6:e20412 pubmed publisher
immunohistochemistry; human	Honardoust D, Varkey M, Hori K, Ding J, Shankowsky H, Tredget E. Small leucine-rich proteoglycans, decorin and fibromodulin, are reduced in postburn hypertrophic scar. Wound Repair Regen. 2011;19:368-78 pubmed publisher
immunohistochemistry; human; 1:50	Kandemir N, Barut F, Gun B, Keser S, Karadayi N, Gun M, et al. Lymphatic differentiation in classic Kaposi's sarcoma: patterns of D2-40 immunoexpression in the course of tumor progression. Pathol Oncol Res. 2011;17:843-51 pubmed publisher
immunohistochemistry; human	Chiong E, Lee I, Dadbin A, Sabichi A, Harris L, Urbauer D, et al. Effects of mTOR inhibitor everolimus (RAD001) on bladder cancer cells. Clin Cancer Res. 2011;17:2863-73 pubmed publisher
immunohistochemistry; human	Yuen J, Sim M, Siml H, Chong T, Lau W, Cheng C, et al. Inhibition of angiogenic and non-angiogenic targets by sorafenib in renal cell carcinoma (RCC) in a RCC xenograft model. Br J Cancer. 2011;104:941-7 pubmed publisher
immunohistochemistry; human; 1:40	Yildirim U, Erdem H, Kayikci A, Sahin A, Uzunlar A, Albayrak A. Cyclooxygenase-2 and survivin in superficial urothelial carcinoma of the bladder and correlation with intratumoural microvessel density. J Int Med Res. 2010;38:1689-99 pubmed
immunohistochemistry; human	Glynn S, Prueitt R, Ridnour L, Boersma B, Dorsey T, Wink D, et al. COX-2 activation is associated with Akt phosphorylation and poor survival in ER-negative, HER2-positive breast cancer. BMC Cancer. 2010;10:626 pubmed publisher
immunohistochemistry; human; 1:100	Lee J, Kim J, Choi J, Kim Y. The presence of a micropapillary component predicts aggressive behaviour in early and advanced gastric adenocarcinomas. Pathology. 2010;42:560-3 pubmed publisher
immunohistochemistry; human; 1:50	Merfeld Clauss S, Gollahalli N, March K, Traktuev D. Adipose tissue progenitor cells directly interact with endothelial cells to induce vascular network formation. Tissue Eng Part A. 2010;16:2953-66 pubmed publisher
immunohistochemistry; human; 1:30	Costache M, Ene A, Simionescu O, Sajin M. Histopathological diagnosis of cutaneous vascular sarcomas. Rom J Morphol Embryol. 2010;51:105-9 pubmed
immunohistochemistry; human	Huynh H. AZD6244 (ARRY-142886) enhances the antitumor activity of rapamycin in mouse models of human hepatocellular carcinoma. Cancer. 2010;116:1315-25 pubmed publisher
immunohistochemistry; human	Lee W, Kim S, Ryu W. Progression and observational frequency of atheromatous plaques in autopsied coronary arteries. Korean Circ J. 2009;39:399-407 pubmed publisher
immunohistochemistry; human	Yang S, Ngo V, Lew G, Chong L, Lee S, Ong W, et al. AZD6244 (ARRY-142886) enhances the therapeutic efficacy of sorafenib in mouse models of gastric cancer. Mol Cancer Ther. 2009;8:2537-45 pubmed publisher
immunohistochemistry; rhesus macaque	Scoles D, Gray D, Hunter J, Wolfe R, Gee B, Geng Y, et al. In-vivo imaging of retinal nerve fiber layer vasculature: imaging histology comparison. BMC Ophthalmol. 2009;9:9 pubmed publisher
immunohistochemistry; human	Lee W, Kim S, Hong S, Lee T, Park E, Kim H, et al. Atherosclerotic progression attenuates the expression of Nogo-B in autopsied coronary artery: pathology and virtual histology intravascular ultrasound analysis. J Korean Med Sci. 2009;24:596-604 pubmed publisher
immunohistochemistry; human; 1:40	Jung I, Gurzu S, Raica M, Cimpean A, Szentirmay Z. The differences between the endothelial area marked with CD31 and CD105 in colorectal carcinomas by computer-assisted morphometrical analysis. Rom J Morphol Embryol. 2009;50:239-43 pubmed
immunohistochemistry; human	Martin D, Boersma B, Yi M, Reimers M, Howe T, Yfantis H, et al. Differences in the tumor microenvironment between African-American and European-American breast cancer patients. PLoS ONE. 2009;4:e4531 pubmed publisher
immunocytochemistry; human; 1:50	Esendagli G, Canpinar H, Yilmaz G, Kaymaz F, Kansu E, Guc D. Fibronectin promotes the phorbol 12-myristate 13-acetate-induced macrophage differentiation in myeloid leukemia cells. Int J Hematol. 2009;89:167-172 pubmed publisher
immunohistochemistry; mouse western blot; mouse	Galvez A, Duran A, Linares J, Pathrose P, Castilla E, Abu Baker S, et al. Protein kinase Czeta represses the interleukin-6 promoter and impairs tumorigenesis in vivo. Mol Cell Biol. 2009;29:104-15 pubmed publisher
immunohistochemistry; human	Gurzu S, Jung I, Prantner I, Ember I, Pávai Z, Mezei T. The expression of cytoskeleton regulatory protein Mena in colorectal lesions. Rom J Morphol Embryol. 2008;49:345-9 pubmed
immunohistochemistry; rhesus macaque; 1:100	Mejía A, Gierbolini L, Jacob B, Westmoreland S. Pediatric hepatic hemangiosarcoma in a rhesus macaque (Macaca mulatta). J Med Primatol. 2009;38:121-4 pubmed publisher
immunohistochemistry; human	Gurzu S, Jung J, Azamfirei L, Mezei T, Cimpean A, Szentirmay Z. The angiogenesis in colorectal carcinomas with and without lymph node metastases. Rom J Morphol Embryol. 2008;49:149-52 pubmed
immunohistochemistry; human	Huynh H, Chow P, Palanisamy N, Salto Tellez M, Goh B, Lee C, et al. Bevacizumab and rapamycin induce growth suppression in mouse models of hepatocellular carcinoma. J Hepatol. 2008;49:52-60 pubmed publisher
immunohistochemistry; human	Huynh H, Chow K, Soo K, Toh H, Choo S, Foo K, et al. RAD001 (everolimus) inhibits tumour growth in xenograft models of human hepatocellular carcinoma. J Cell Mol Med. 2009;13:1371-80 pubmed publisher
immunohistochemistry; human	Yamac D, Ayyildiz T, Coskun U, Akyurek N, Dursun A, Seckin S, et al. Cyclooxygenase-2 expression and its association with angiogenesis, Helicobacter pylori, and clinicopathologic characteristics of gastric carcinoma. Pathol Res Pract. 2008;204:527-36 pubmed publisher
immunohistochemistry; human; 1:50	Longatto Filho A, Oliveira T, Pinheiro C, de Carvalho M, Curioni O, Mercante A, et al. How useful is the assessment of lymphatic vascular density in oral carcinoma prognosis?. World J Surg Oncol. 2007;5:140 pubmed
immunohistochemistry; human	Gurzu S, Jung J, Azamfirei L, Mezei T, Cimpean A. The aspects of angiogenesis in anal canal carcinomas compared with that in colorectal carcinomas. Rom J Morphol Embryol. 2007;48:349-53 pubmed
immunohistochemistry; mouse	Huynh H, Teo C, Soo K. Bevacizumab and rapamycin inhibit tumor growth in peritoneal model of human ovarian cancer. Mol Cancer Ther. 2007;6:2959-66 pubmed
immunohistochemistry; human; 1:40	Lee F, Wen M, Wang J. Epithelioid angiosarcoma arising in a deep-seated plexiform schwannoma: a case report and literature review. Hum Pathol. 2007;38:1096-101 pubmed
immunohistochemistry; human	Vardar E, Gunlusoy B, Arslan M, Kececi S. Myointimoma of the glans penis. Pathol Int. 2007;57:158-61 pubmed
immunohistochemistry; human	Bolat F, Kayaselcuk F, Nursal T, Yagmurdur M, Bal N, Demirhan B. Microvessel density, VEGF expression, and tumor-associated macrophages in breast tumors: correlations with prognostic parameters. J Exp Clin Cancer Res. 2006;25:365-72 pubmed
immunohistochemistry; human	Ghersi G, Zhao Q, Salamone M, Yeh Y, Zucker S, Chen W. The protease complex consisting of dipeptidyl peptidase IV and seprase plays a role in the migration and invasion of human endothelial cells in collagenous matrices. Cancer Res. 2006;66:4652-61 pubmed
immunohistochemistry; human	Fabris L, Cadamuro M, Fiorotto R, Roskams T, Spirli C, Melero S, et al. Effects of angiogenic factor overexpression by human and rodent cholangiocytes in polycystic liver diseases. Hepatology. 2006;43:1001-12 pubmed
immunohistochemistry; human; 1:100	Kim S, Cho N, Kim K, Lee J, Koo B, Kim J, et al. Correlations of oral tongue cancer invasion with matrix metalloproteinases (MMPs) and vascular endothelial growth factor (VEGF) expression. J Surg Oncol. 2006;93:330-7 pubmed
immunohistochemistry; human; 1:50	Ates L, Kapran Y, Erbil Y, Barbaros U, Dizdaroglu F. Cystic lymphangioma of the right adrenal gland. Pathol Oncol Res. 2005;11:242-4 pubmed
immunohistochemistry; human; 1:25	Reis R, Reis Filho J, Longatto Filho A, Tomarev S, Silva P, Lopes J. Differential Prox-1 and CD 31 expression in mucousae, cutaneous and soft tissue vascular lesions and tumors. Pathol Res Pract. 2005;201:771-6 pubmed
immunohistochemistry; human; 1:50	Wang Z, Huang G, Yan P, Liang R, Wang J, Yan Q, et al. Ectopic cervical anaplastic ependymoma. Pathol Int. 2005;55:781-4 pubmed
immunohistochemistry; human; 1:30	Yazici A, Tursen U, Apa D, Ikizoglu G, Api H, Baz K, et al. The changes in expression of ICAM-3, Ki-67, PCNA, and CD31 in psoriatic lesions before and after methotrexate treatment. Arch Dermatol Res. 2005;297:249-55 pubmed
immunohistochemistry; rat; 1:25	Sato Y, Araki H, Kato J, Nakamura K, Kawano Y, Kobune M, et al. Human mesenchymal stem cells xenografted directly to rat liver are differentiated into human hepatocytes without fusion. Blood. 2005;106:756-63 pubmed
immunohistochemistry; human	Uluoglu O, Akyurek N, Uner A, Coskun U, Ozdemir A, Gokcora N. Interdigitating dendritic cell tumor with breast and cervical lymph-node involvement: a case report and review of the literature. Virchows Arch. 2005;446:546-54 pubmed
immunohistochemistry; human	da Costa C, Annels N, Faaij C, Forsyth R, Hogendoorn P, Egeler R. Presence of osteoclast-like multinucleated giant cells in the bone and nonostotic lesions of Langerhans cell histiocytosis. J Exp Med. 2005;201:687-93 pubmed
immunohistochemistry; human	Tertemiz F, Kayisli U, Arici A, Demir R. Apoptosis contributes to vascular lumen formation and vascular branching in human placental vasculogenesis. Biol Reprod. 2005;72:727-35 pubmed
flow cytometry; human; tbl 1	Tan P, Chan C, Xue S, Dong R, Ananthesayanan B, Manunta M, et al. Phenotypic and functional differences between human saphenous vein (HSVEC) and umbilical vein (HUVEC) endothelial cells. Atherosclerosis. 2004;173:171-83 pubmed
	Lu G, Xu Y, Liu Q, Chen M, Sun H, Wang P, et al. An instantly fixable and self-adaptive scaffold for skull regeneration by autologous stem cell recruitment and angiogenesis. Nat Commun. 2022;13:2499 pubmed publisher
	Swaminathan B, Youn S, Naiche L, Du J, Villa S, Metz J, et al. Endothelial Notch signaling directly regulates the small GTPase RND1 to facilitate Notch suppression of endothelial migration. Sci Rep. 2022;12:1655 pubmed publisher
	Peng Q, Sha K, Liu Y, Chen M, Xu S, Xie H, et al. mTORC1-Mediated Angiogenesis is Required for the Development of Rosacea. Front Cell Dev Biol. 2021;9:751785 pubmed publisher
	Rimal R, Desai P, Marquez A, Sieg K, Marquardt Y, Singh S. 3-D vascularized breast cancer model to study the role of osteoblast in formation of a pre-metastatic niche. Sci Rep. 2021;11:21966 pubmed publisher
	Wu D, Lombaert I, DeLeon M, Pradhan Bhatt S, Witt R, Harrington D, et al. Immunosuppressed Miniswine as a Model for Testing Cell Therapy Success: Experience With Implants of Human Salivary Stem/Progenitor Cell Constructs. Front Mol Biosci. 2021;8:711602 pubmed publisher
	Shen M, Wang M, Liu Z, Wang S, Xie Y. [Gly14]-Humanin Ameliorates High Glucose-Induced Apoptosis by Inhibiting the Expression of MicroRNA-155 in Endothelial Microparticles. Diabetes Metab Syndr Obes. 2021;14:2335-2347 pubmed publisher
	Li L, He Y, Tang H, Mao W, Ni H, Lyu F, et al. Cerebrospinal Fluid Pulsation Stress Promotes the Angiogenesis of Tissue-Engineered Laminae. Stem Cells Int. 2020;2020:8026362 pubmed publisher
	Abe J, Ko K, Kotla S, Wang Y, Paez Mayorga J, Shin I, et al. MAGI1 as a link between endothelial activation and ER stress drives atherosclerosis. JCI Insight. 2019;4: pubmed publisher
	Peng K, Li X, Wu C, Wang Y, Yu J, Zhang J, et al. Derivation of Haploid Trophoblast Stem Cells via Conversion In Vitro. iScience. 2019;11:508-518 pubmed publisher
	Perin S, McCann C, De Coppi P, Thapar N. Isolation and characterisation of mouse intestinal mesoangioblasts. Pediatr Surg Int. 2019;35:29-34 pubmed publisher
	Kabir A, Lee T, Pan H, Berry J, Krchma K, Wu J, et al. Requisite endothelial reactivation and effective siRNA nanoparticle targeting of Etv2/Er71 in tumor angiogenesis. JCI Insight. 2018;3: pubmed publisher
	Maharani A, Aoshima K, Onishi S, Gulay K, Kobayashi A, Kimura T. Cellular atypia is negatively correlated with immunohistochemical reactivity of CD31 and vWF expression levels in canine hemangiosarcoma. J Vet Med Sci. 2018;80:213-218 pubmed publisher
	Kulhankova K, Kinney K, Stach J, Gourronc F, Grumbach I, Klingelhutz A, et al. The Superantigen Toxic Shock Syndrome Toxin 1 Alters Human Aortic Endothelial Cell Function. Infect Immun. 2018;86: pubmed publisher
	Stojic I, Zivkovic V, Srejovic I, Nikolic T, Jeremic N, Jeremic J, et al. Cisplatin and cisplatin analogues perfusion through isolated rat heart: the effects of acute application on oxidative stress biomarkers. Mol Cell Biochem. 2018;439:19-33 pubmed publisher
	Karki S, Ngo D, Farb M, Park S, Saggese S, Hamburg N, et al. WNT5A regulates adipose tissue angiogenesis via antiangiogenic VEGF-A165b in obese humans. Am J Physiol Heart Circ Physiol. 2017;313:H200-H206 pubmed publisher
	Seaman S, Zhu Z, Saha S, Zhang X, Yang M, Hilton M, et al. Eradication of Tumors through Simultaneous Ablation of CD276/B7-H3-Positive Tumor Cells and Tumor Vasculature. Cancer Cell. 2017;31:501-515.e8 pubmed publisher
	Rakocevic J, Kojic S, Orlic D, Stankovic G, Ostojic M, Petrovic O, et al. Co-expression of vascular and lymphatic endothelial cell markers on early endothelial cells present in aspirated coronary thrombi from patients with ST-elevation myocardial infarction. Exp Mol Pathol. 2016;100:31-8 pubmed publisher
	Ku C, Zerboni L, Ito H, Graham B, Wallace M, Arvin A. Varicella-zoster virus transfer to skin by T Cells and modulation of viral replication by epidermal cell interferon-alpha. J Exp Med. 2004;200:917-25 pubmed
	Ockleford C, Smith R, Byrne S, Sanders R, Bosio P. Confocal laser scanning microscope study of cytokeratin immunofluorescence differences between villous and extravillous trophoblast: cytokeratin downregulation in pre-eclampsia. Microsc Res Tech. 2004;64:43-53 pubmed
	Kabukcuoglu F, Kabukcuoglu Y, Yilmaz B, Erdem Y, Evren I. Mazabraud's syndrome: intramuscular myxoma associated with fibrous dysplasia. Pathol Oncol Res. 2004;10:121-3 pubmed
	Chang C, Ko P, Hsu L, Ko Y, Ko Y, Chen C, et al. Highly increased cell proliferation activity in the restenotic hemodialysis vascular access after percutaneous transluminal angioplasty: implication in prevention of restenosis. Am J Kidney Dis. 2004;43:74-84 pubmed
	Rossi G, Valli R, Bertolini F, Sighinolfi P, Losi L, Cavazza A, et al. Does mesoappendix infiltration predict a worse prognosis in incidental neuroendocrine tumors of the appendix? A clinicopathologic and immunohistochemical study of 15 cases. Am J Clin Pathol. 2003;120:706-11 pubmed
	Autieri M, Kelemen S, Thomas B, Feller E, Goldman B, Eisen H. Allograft inflammatory factor-1 expression correlates with cardiac rejection and development of cardiac allograft vasculopathy. Circulation. 2002;106:2218-23 pubmed
	Saimura M, Nagai E, Mizumoto K, Maehara N, Minamishima Y, Katano M, et al. Tumor suppression through angiogenesis inhibition by SUIT-2 pancreatic cancer cells genetically engineered to secrete NK4. Clin Cancer Res. 2002;8:3243-9 pubmed
	Tanaka K, Sonoo H, Kurebayashi J, Nomura T, Ohkubo S, Yamamoto Y, et al. Inhibition of infiltration and angiogenesis by thrombospondin-1 in papillary thyroid carcinoma. Clin Cancer Res. 2002;8:1125-31 pubmed

image

image 1 :

Formalin-fixed, paraffin-embedded human tonsil stained with CD31 antibody using peroxidase-conjugate and AEC chromogen. Note cell membrane staining of endothelial cells.

product information

Product Type :

Antibody

Product Name :

CD31 Monoclonal Antibody (JC/70A)

Catalog # :

MA5-13188

Quantity :

500 µL

Price :

US 426

Clonality :

Monoclonal

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 1:2, Immunocytochemistry: 1:10-1:100, Immunohistochemistry (Paraffin): 1:100, Western Blot: 1:1,000

Species :

Human

Clone :

JC/70A

Isotype :

IgG1, kappa

Storage :

4° C

Description :

CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) is an inhibitory coreceptor involved in regulation of T cell and B cell signaling by a dual immunoreceptor tyrosine-based inhibitory motif (ITIM) that upon associated kinases-mediated phosphorylation provide docking sites for protein-tyrosine phosphatases. CD31 is expressed ubiquitously within the vascular compartment and is located mainly at junctions between adjacent cells. N-terminal Ig-like domain of CD31 is responsible for its homophilic binding, which plays an important role in cell-cell interactions. CD31 is a multifunctional molecule with diverse roles in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, negative regulation of immunoreceptor signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. It is one of key regulatory molecules in vascular system.

Immunogen :

Membrane preparation of a spleen from a patient with hairy cell leukemia

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:2, Immunocytochemistry: 1:10-1:100, Immunohistochemistry (Paraffin): 1:100, Western Blot: 1:1,000

Aliases :

C85791; CD31; CD31 antigen; CD31, PECAM-1; CD31/EndoCAM; endoCAM; GPIIA'; I79_008304; PECA1; Pecam; PECAM1; Pecam-1; platelet and endothelial cell adhesion molecule 1; platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule-1; platelet/endothelial cell adhesion molecule (CD31 antigen); platelet/endothelial cell adhesion molecule 1; type I transmembrane endothelial adhesion molecule

more info or order :

Invitrogen product webpage