This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Cytokeratin Pan Type II Monoclonal Antibody (AE3)
catalog :
MA5-13150
quantity :
100 ug
price :
US 359.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
AE3

The same clone is also sold as:
reactivity :
human
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
citations: 8
Reference
Balic M, Rapp N, Stanzer S, Lin H, Strutz J, Szkandera J, et al. Novel immunofluorescence protocol for multimarker assessment of putative disseminating breast cancer stem cells. Appl Immunohistochem Mol Morphol. 2011;19:33-40 pubmed publisher
Chang C, Chiou P, Chen W, Li Y, Yiu J, Cheng Y, et al. Assessment of the tumorigenesis and drug susceptibility of three new canine mammary tumor cell lines. Res Vet Sci. 2010;88:285-93 pubmed publisher
Gil da Costa R, Santos M, Amorim I, Lopes C, Pereira P, Faustino A. An immunohistochemical study of feline endometrial adenocarcinoma. J Comp Pathol. 2009;140:254-9 pubmed publisher
Esendagli G, Yilmaz G, Canpinar H, Gunel Ozcan A, Guc M, Guc D. Coexistence of different tissue tumourigenesis in an N-methyl-N-nitrosourea-induced mammary carcinoma model: a histopathological report in Sprague-Dawley rats. Lab Anim. 2009;43:60-4 pubmed publisher
Hosoya A, Kim J, Cho S, Jung H. BMP4 signaling regulates formation of Hertwig's epithelial root sheath during tooth root development. Cell Tissue Res. 2008;333:503-9 pubmed publisher
Offerhaus G, Schipper M, Lazenby A, Montgomery E, Morsink F, Bende R, et al. Graft-versus-host-like disease complicating thymoma: lack of AIRE expression as a cause of non-hereditary autoimmunity?. Immunol Lett. 2007;114:31-7 pubmed
Atinkaya C, Ozlem Küçük N, Koparal H, Aras G, Sak S, Ozdemir N. Mediastinal intraoperative radioisotope sentinel lymph node mapping in non-small-cell lung cancer. Nucl Med Commun. 2005;26:717-20 pubmed
Apaydin R, Gurbuz Y, Bayramgurler D, Muezzinoglu B, Bilen N. Cytokeratin expression in lichen amyloidosus and macular amyloidosis. J Eur Acad Dermatol Venereol. 2004;18:305-9 pubmed
product information
Product Type :
Antibody
Product Name :
Cytokeratin Pan Type II Monoclonal Antibody (AE3)
Catalog # :
MA5-13150
Quantity :
100 ug
Price :
US 359.00
Clonality :
Monoclonal
Purity :
purified
Host :
Mouse
Reactivity :
Human
Applications :
Immunohistochemistry (Paraffin): 1:250-1:500, Western Blot: 2 ug/mL
Species :
Human
Clone :
AE3
Isotype :
IgG1
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
Cytokeratin pan is part of a subfamily of intermediate filament proteins that are characterized by remarkable biochemical diversity, and represented in human epithelial tissues by at least 20 different polypeptides. Cytokeratins range in molecular weight between 40 kDa- 68 kDa, and an isoelectric pH between 4.9-7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays. The composition of cytokeratin pairs vary with the epithelial cell type, stage of differentiation, cellular growth environment, and disease state. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis.
Immunogen :
Human epidermal Keratin
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry (Paraffin): 1:250-1:500, Western Blot: 2 ug/mL
Aliases :
2310016L08Rik; 3300001P10Rik; 57kd keratin; 57kDa keratin; 58 kda cytokeratin; 60-kDa keratin; 65 kDa cytokeratin; 67 kDa cytokeratin; AA960620; AI507495; AL022697; alpha keratin; AU019895; AW108092; AW146334; BB005427; Card2; CK 2e; CK1; CK-1; CK-2e; CK3; CK-3; CK4; CK-4; CK5; CK-5; CK6A; CK-6A; CK6C; CK-6C; CK6D; CK-6D; CK-6E; CK7; CK-7; CK-72; CK8; CK-8; CYK4; CYK8; CYKER; cytokeratin 1; cytokeratin 3; cytokeratin 4; cytokeratin 5; cytokeratin 6A; cytokeratin 6C; cytokeratin 6D; cytokeratin 7; cytokeratin 8; cytokeratin 8 (370 AA); cytokeratin endo A; Cytokeratin otokeratin; cytokeratin type II, component Ib/c; cytokeratin type II, component III; Cytokeratin-1; Cytokeratin-2e; cytokeratin-3; Cytokeratin-4; cytokeratin-5; Cytokeratin-6A; cytokeratin-6C; Cytokeratin-6D; cytokeratin-6E; cytokeratin-7; Cytokeratin-72; cytokeratin-8; Cytokeratin-A; cytoskeletal 57 kDa keratin; D15Wsu77e; DDD; DDD1; ear specific cytokeratin; EBS2; EGK_03684; EGK_03685; EHK; EHK1; EndoA; epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types; epidermolytic hyperkeratosis 1; epithelial keratin 1; epithelial keratin 2e; Epithelial keratin-1; Epithelial keratin-2e; EPPK; Hair alpha protein; Hom s 5; K1; K2C7; K2C8; K2E; K3; K3 keratin; K4; K5; K6A; K6a keratin; K6C; K6D; K6irs; K6IRS2; K7; K72; K8; kamp-keratin derived antimicrobial peptide; Kb1; Kb2; Kb35; Kb4; Kb7; KDAMP; KER1; Ker2; KERA; keratin; keratin 1; keratin 1 (epidermolytic hyperkeratosis); keratin 1, type II; keratin 2; keratin 2 (epidermal ichthyosis bullosa of Siemens); keratin 2 epidermis; keratin 2, type II; keratin 2A; keratin 2A (epidermal ichthyosis bullosa of Siemens); keratin 3; keratin 3, type II; keratin 4; keratin 4, type II; keratin 5; keratin 5 (epidermolysis bullosa simplex Dowling-Meara/Kobner/Weber-Cockayne types); keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types); keratin 5, type II; keratin 6 alpha; keratin 6, inner root sheath, 2; keratin 6A; keratin 6A, , type II; keratin 6A, type II; keratin 7; keratin 7, type II; keratin 72; keratin 72, pseudogene; keratin 72, type II; keratin 8; keratin 8, type II; keratin 86; keratin complex 2, basic, gene 1; keratin complex 2, basic, gene 17; keratin complex 2, basic, gene 35; keratin complex 2, basic, gene 4; keratin complex 2, basic, gene 5; keratin complex 2, basic, gene 6a; keratin complex 2, basic, gene 6c; keratin complex 2, basic, gene 7; keratin complex 2, basic, gene 8; keratin complex 2, gene 17; keratin complex 2, gene 6a; keratin IV; keratin K3; keratin K6; keratin K6h; keratin protein K6irs; keratin, 55K type II cytoskeletal; keratin, epidermal type II, K6A; keratin, simple epithelial type I, K7; keratin, type II cytoskeletal 1; Keratin, type II cytoskeletal 2 epidermal; keratin, type II cytoskeletal 3; Keratin, type II cytoskeletal 4; keratin, type II cytoskeletal 5; keratin, type II cytoskeletal 59 kDa, component IV; keratin, type II cytoskeletal 60 kDa, component III; keratin, type II cytoskeletal 6A; keratin, type II cytoskeletal 6C; keratin, type II cytoskeletal 7; Keratin, type II cytoskeletal 72; keratin, type II cytoskeletal 8; Keratin, type II cytoskeletal cochleal; keratin-1; Keratin-2 epidermis; keratin-2e; Keratin-3; Keratin-4; keratin-5; keratin-6A; Keratin-6-alpha; keratin-6C; keratin-7; Keratin-72; keratin-8; KERIB; KO; Krt1; krt1 {ECO:0000250; KRT1A; Krt2; krt2 {ECO:0000250; Krt-2.1; Krt-2.4; Krt-2.8; Krt2-1; Krt2-17; Krt2-2; Krt2-35; Krt2-4; Krt2-5; Krt2-6; Krt2-6a; Krt2-6c; Krt2-7; KRT2-8; KRT2A; KRT2E; KRT3; KRT4; krt4 {ECO:0000250; Krt5; KRT5A; KRT6; Krt6a; KRT6C; KRT6D; KRT6IRS2; Krt7; krt7 {ECO:0000250; Krt72; Krt72-ps; Krt8; Krt86; KRTA; KRTE; LOC683313; LOW QUALITY PROTEIN: keratin, type II cytoskeletal 7; MGC116967; MGC116968; mK6[a]; MK6a; mK6-alpha; NEPPK; otokeratin; pan keratin; PC3; Sak57; sarcolectin; SCL; similar to keratin 7; similar to keratin complex 2, basic, gene 6a; Tfip8; tuftelin interacting protein 8
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA