S100 Monoclonal Antibody (4C4.9) | Invitrogen MA5-12969 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

S100 Monoclonal Antibody (4C4.9)

catalog :

MA5-12969

quantity :

500 µL

price :

US 345.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

4C4.9

reactivity :

African green monkey, human, mouse, rat, bovine

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 68

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - frozen section; rat; 1:100; loading ...; fig 4a	Koike T, Tanaka S, Hirahara Y, Oe S, Kurokawa K, Maeda M, et al. Morphological characteristics of p75 neurotrophin receptor-positive cells define a new type of glial cell in the rat dorsal root ganglia. J Comp Neurol. 2019;527:2047-2060 pubmed publisher
immunohistochemistry - paraffin section; human; 1:1000; loading ...; tbl 1	Cobo J, Abbate F, de Vicente J, Cobo J, Vega J. Searching for proprioceptors in human facial muscles. Neurosci Lett. 2017;640:1-5 pubmed publisher
immunohistochemistry; human; 1:100	Tonyali S, Yazici S, Yeşilırmak A, Ergen A. The Ewing's Sarcoma Family of Tumors of Urinary Bladder: A Case Report and Review of the Literature. Balkan Med J. 2016;33:462-6 pubmed publisher
immunohistochemistry - paraffin section; rat; fig 4b	Ozbek Z, Kocman A, Ozatik O, Söztutar E, Ozkara E, Köse A, et al. Nerve Tissue Prefabrication Inside the Rat Femoral Bone: Does It Work?. Turk Neurosurg. 2017;27:648-655 pubmed publisher
immunohistochemistry - paraffin section; human; 1:1600; loading ...; fig 2a	Sundarkrishnan L, Bradish J, Oliai B, Hosler G. Cutaneous Cellular Pseudoglandular Schwannoma: An Unusual Histopathologic Variant. Am J Dermatopathol. 2016;38:315-8 pubmed publisher
immunohistochemistry - paraffin section; human; fig 1c	Li L, Xu L, Yan J, Zhen Z, Ji Y, Liu C, et al. CXCR2-CXCL1 axis is correlated with neutrophil infiltration and predicts a poor prognosis in hepatocellular carcinoma. J Exp Clin Cancer Res. 2015;34:129 pubmed publisher
immunohistochemistry; human; 1:100; fig 12	Costache M, Dumitru A, PÄƒtraÅŸcu O, Popa Cherecheanu D, BÄƒdilÄƒ P, Miu J, et al. A challenging case of ocular melanoma. Rom J Morphol Embryol. 2015;56:817-22 pubmed
immunohistochemistry - paraffin section; mouse; fig 5b immunohistochemistry - paraffin section; human; fig 5a	Alonso Curbelo D, Osterloh L, CaÃ±Ã³n E, Calvo T, MartÃnez Herranz R, Karras P, et al. RAB7 counteracts PI3K-driven macropinocytosis activated at early stages of melanoma development. Oncotarget. 2015;6:11848-62 pubmed
immunohistochemistry - paraffin section; human	Cao Y, Zhu M, Mao R, Cao R, Yu G, Niu A. Oncocytic carcinoma of the salivary gland with thymoma: A case report and review of the literature. Oncol Lett. 2015;9:681-684 pubmed
immunohistochemistry; human; fig 1	Cabo R, Alonso P, ViÃ±a E, VÃ¡zquez G, Gago A, Feito J, et al. ASIC2 is present in human mechanosensory neurons of the dorsal root ganglia and in mechanoreceptors of the glabrous skin. Histochem Cell Biol. 2015;143:267-76 pubmed publisher
immunohistochemistry - paraffin section; human; 1:50	Sajin M, Luchian M, Hodorogea PrisÄƒcaru A, Dumitru A, PÄƒtraÅŸcu O, Costache D, et al. Trichilemmal carcinoma - a rare cutaneous malignancy: report of two cases. Rom J Morphol Embryol. 2014;55:687-91 pubmed
immunohistochemistry - paraffin section; human; 1:100	Costache M, PÄƒtraÅŸcu O, Dumitru A, Costache D, Voinea L, Simionescu O, et al. Histopathological findings concerning ocular melanomas. Rom J Morphol Embryol. 2014;55:649-53 pubmed
immunohistochemistry; human; 1:100	Shen W, Wang Y, Chang J, Yu S, Chen H, Chiang C. Perineural invasion and expression of nerve growth factor can predict the progression and prognosis of oral tongue squamous cell carcinoma. J Oral Pathol Med. 2014;43:258-64 pubmed
immunohistochemistry; rat; 1:100	Kun A, Seprényi G, Varro A, Papp J, Pataricza J. Neurogenic contraction induced by the antiarrhythmic compound, AVE 0118, in rat small mesenteric arteries. Basic Clin Pharmacol Toxicol. 2014;115:315-20 pubmed publisher
immunohistochemistry; human	Horak M, Handl M, Podskubka A, Kana R, Adler J, Povysil C. Comparison of the cellular composition of two different chondrocyte-seeded biomaterials and the results of their transplantation in humans. Folia Biol (Praha). 2014;60:1-9 pubmed
immunohistochemistry; human; 1:100	Wu Y, Wang Y, Chang J, Chen H, Sun A, Chiang C. Langerhans cells in odontogenic epithelia of odontogenic fibromas. J Formos Med Assoc. 2013;112:756-60 pubmed publisher
immunohistochemistry; mouse	Marsh Durban V, Deuker M, Bosenberg M, Phillips W, McMahon M. Differential AKT dependency displayed by mouse models of BRAFV600E-initiated melanoma. J Clin Invest. 2013;123:5104-18 pubmed publisher
immunohistochemistry; human; 1:1000	de Carlos F, Cobo J, Macias E, Feito J, Cobo T, Calavia M, et al. The sensory innervation of the human pharynx: searching for mechanoreceptors. Anat Rec (Hoboken). 2013;296:1735-46 pubmed publisher
immunohistochemistry - paraffin section; human; 1:50; tbl 2	Qiu S, Wei X, Huang W, Wu M, Qin Y, Li Y, et al. Diagnostic and therapeutic strategy and the most efficient prognostic factors of breast malignant fibrous histiocytoma. Sci Rep. 2013;3:2529 pubmed publisher
immunohistochemistry; human; 1:200	Hwang M, Wu P, Chen C, Chen C, Chen C. A rare malignancy of the parotid gland in a 13-year-old Taiwanese boy: case report of a mammary analogue secretory carcinoma of the salivary gland with molecular study. Med Mol Morphol. 2014;47:57-61 pubmed publisher
immunohistochemistry; rat; 1:100	Hotta S, Nagaoka T, Taguchi K, Nakatani Y, Utsnomiya I, Masuda Y, et al. Neurophysiological and immunohistochemical studies of IgG anti-GM1 monoclonal antibody on neuromuscular transmission: effects in rat neuromuscular junctions. Neurol Sci. 2014;35:205-13 pubmed publisher
immunohistochemistry; human; 1:50	Kara T, Serinsoz E, Arpaci R, Gubur O, Orekici G, Ata A, et al. Contribution of DOG1 expression to the diagnosis of gastrointestinal stromal tumors. Pathol Res Pract. 2013;209:413-7 pubmed publisher
immunohistochemistry; human; 1:1000	Calavia M, Vina E, Menendez Gonzalez M, Lopez Muñiz A, Alonso Guervós M, Cobo J, et al. Evidence of nestin-positive cells in the human cutaneus Meissner and Pacinian corpuscles. CNS Neurol Disord Drug Targets. 2012;11:869-77 pubmed
immunohistochemistry; human	Apuhan T, Yildirim Y, Simşek T, Yilmaz F, Yilmaz F. Concha bullosa surgery and the distribution of human olfactory neuroepithelium. Eur Arch Otorhinolaryngol. 2013;270:953-7 pubmed publisher
immunohistochemistry; human; 1:100	Wang Z, Gong Q, Fan Q. Expression of E-cadherin in angiomyolipoma. Hum Pathol. 2012;43:2348-53 pubmed publisher
immunohistochemistry; human	Zhou Z, Yu M, Yang S, Zhou J, Sun R, Yang G. Dural angioleiomyoma of the middle cranial fossa: a case report and review of the literature. Brain Tumor Pathol. 2013;30:117-21 pubmed publisher
immunohistochemistry; human; 1:2000	Kim S, Chun C, Chun K, Jo H, Kim K. Histological assessment of mechanoreceptors in Achilles allografts after anterior cruciate ligament reconstruction. Am J Sports Med. 2012;40:2061-5 pubmed publisher
immunohistochemistry; human; 1:100	Zhao L, Luo J, Zhang H, Da J. Pigmented paraganglioma of the kidney: a case report. Diagn Pathol. 2012;7:77 pubmed publisher
immunohistochemistry; African green monkey	Cabo R, G lvez M, San Jos I, Laur R, L pez Mu iz A, Garc a Su rez O, et al. Immunohistochemical localization of acid-sensing ion channel 2 (ASIC2) in cutaneous Meissner and Pacinian corpuscles of Macaca fascicularis. Neurosci Lett. 2012;516:197-201 pubmed
immunocytochemistry; human immunohistochemistry; human	Reinisch C, Tschachler E. The dimensions and characteristics of the subepidermal nerve plexus in human skin--terminal Schwann cells constitute a substantial cell population within the superficial dermis. J Dermatol Sci. 2012;65:162-9 pubmed publisher
immunohistochemistry; human	Ersoz S, Turgutalp H, Mungan S, Güvendı G, Guven S. Cotyledonoid leiomyoma of uterus: a case report. Turk Patoloji Derg. 2011;27:257-60 pubmed publisher
immunohistochemistry; human; 1:200	Ozluk Y, Kilicaslan I, Kazancioglu R, Demirkesen C, Derin D, Mandel N. Intraglomerular crescentic metastases of malignant melanoma. Hum Pathol. 2011;42:2025-8 pubmed publisher
immunohistochemistry; human; 1:200	Ambrosini Spaltro A, Melissari M. Papillary urothelial carcinoma of the bladder with exuberant pseudosarcomatous stromal reaction following radiation therapy. Int J Surg Pathol. 2011;19:263-7 pubmed publisher
immunohistochemistry; human; 1:1000	Calavia M, Montano J, Garcia Suarez O, Feito J, Guervós M, Germana A, et al. Differential localization of Acid-sensing ion channels 1 and 2 in human cutaneus pacinian corpuscles. Cell Mol Neurobiol. 2010;30:841-8 pubmed publisher
immunohistochemistry; human; 1:1	Kaya C, Bogaert G, De Ridder D, Schwentner C, Fritsch H, Oswald J, et al. Extracellular matrix degradation and reduced neural density in children with intrinsic ureteropelvic junction obstruction. Urology. 2010;76:185-9 pubmed publisher
immunohistochemistry; human; 1:100	Jung S, Yim S, Hu H, Jung C, Lee S, Kim D, et al. Copy number alterations and expression profiles of candidate genes in a pulmonary inflammatory myofibroblastic tumor. Lung Cancer. 2010;70:152-7 pubmed publisher
immunohistochemistry; human; 1:150	Behzatoglu K, Durak H, Canberk S, Aydin O, Huq G, Oznur M, et al. Giant cell tumor-like lesion of the urinary bladder: a report of two cases and literature review; giant cell tumor or undifferentiated carcinoma?. Diagn Pathol. 2009;4:48 pubmed publisher
immunohistochemistry; human	Kefeli M, Kandemir B, Akpolat I, Yildirim A, Kokcu A. Rhabdomyosarcoma arising in a mature cystic teratoma with contralateral serous carcinoma: case report and review of the literature. Int J Gynecol Pathol. 2009;28:372-5 pubmed publisher
immunohistochemistry; human	Zurac S, Andrei R, Petsakos G, Nichita L, Bastian A, Micu G, et al. Cutaneous metastases of malignant melanoma--how difficult can it be?. Rom J Intern Med. 2008;46:375-8 pubmed
immunohistochemistry; human; 1:50	Boldorini R, Panzarasa G, Girardi P, Monga G. Primary choroid plexus papilloma of the sacral nerve roots. J Neurosurg Spine. 2009;10:51-3 pubmed publisher
immunohistochemistry; human; 1:1000	Froio E, D Adda T, Fellegara G, Martella E, Caruana P, Pruneri G, et al. Uterine carcinosarcoma metastatic to the lung as large-cell neuroendocrine carcinoma with synchronous sarcoid granulomatosis. Lung Cancer. 2009;64:371-7 pubmed publisher
immunohistochemistry; rat; 1:200	Esendagli G, Yilmaz G, Canpinar H, Gunel Ozcan A, Guc M, Guc D. Coexistence of different tissue tumourigenesis in an N-methyl-N-nitrosourea-induced mammary carcinoma model: a histopathological report in Sprague-Dawley rats. Lab Anim. 2009;43:60-4 pubmed publisher
immunohistochemistry; human	Uzum N, Kose F, Ataoglu O. Metastatic malignant melanoma of the uterine cervix: first diagnosed on liquid-based cytology. Diagn Cytopathol. 2008;36:769-72 pubmed publisher
immunohistochemistry; human	Kefeli M, Yildiz L, Akpolat I, Balci P, Ozen N. The coexistence of invasive ductal carcinoma and malignant phyllodes tumor with liposarcomatous and chondrosarcomatous differentiation in the same breast in a post-osteosarcoma case. Pathol Res Pract. 2008;204:919-23 pubmed publisher
immunohistochemistry; human; 1:100	Akbulut M, Gunhan Bilgen I, Zekioglu O, Duygulu G, Oktay A, Ozdemir N. Fine needle aspiration cytology of inflammatory myofibroblastic tumour (inflammatory pseudotumour) of the breast: a case report and review of the literature. Cytopathology. 2007;18:384-7 pubmed
immunohistochemistry; human; 1:50	Yorulmaz G, Erdogan G, Pestereli H, Savas B, Karaveli F. Epithelioid leiomyosarcoma with rhabdoid features. Wien Klin Wochenschr. 2007;119:557-60 pubmed
immunohistochemistry; human	Vardar E, Gunlusoy B, Arslan M, Kececi S. Myointimoma of the glans penis. Pathol Int. 2007;57:158-61 pubmed
immunohistochemistry; human; 1:4000	Laco J, Simakova E, Slezak R, Tucek L, Mottl R, Spacek J, et al. Low grade myofibroblastic sarcoma of tongue: a case report. Cesk Patol. 2006;42:150-3 pubmed
immunohistochemistry; human; 1:50	Mayerl C, Lukasser M, Sedivy R, Niederegger H, Seiler R, Wick G. Atherosclerosis research from past to present--on the track of two pathologists with opposing views, Carl von Rokitansky and Rudolf Virchow. Virchows Arch. 2006;449:96-103 pubmed
immunohistochemistry; human; 1:50	Cao Y, Zhang M, Wang J, Zhang W, Li G, Zhao J. Recurrent intracranial hemangiopericytoma with multiple metastases. Chin Med J (Engl). 2006;119:169-73 pubmed
immunohistochemistry; human	Yesim G, Gupse T, Zafer U, Ahmet A. Mesenchymal hamartoma of the liver in adulthood: immunohistochemical profiles, clinical and histopathological features in two patients. J Hepatobiliary Pancreat Surg. 2005;12:502-7 pubmed
immunohistochemistry; mouse; 1:100	Corvetti L, Aztiria E, Domenici L. Reduction of GFAP induced by long dark rearing is not restricted to visual cortex. Brain Res. 2006;1067:146-53 pubmed
immunohistochemistry; human; 1:250	Bikmaz K, Cosar M, Kurtkaya Yapicier O, Iplikcioglu A, Gokduman C. Recurrent solitary fibrous tumour in the cerebellopontine angle. J Clin Neurosci. 2005;12:829-32 pubmed
immunohistochemistry; human; 1:100	Yilmazbayhan D, Ates L, Dilege S, Gulluoglu M, Tanju S, Kalayci G. Pulmonary large cell carcinoma with rhabdoid phenotype. Ann Diagn Pathol. 2005;9:223-6 pubmed
immunohistochemistry; human; 1:100	Ozguc H, Yilmazlar T, Yerci O, Soylu R, Tümay V, Filiz G, et al. Analysis of prognostic and immunohistochemical factors in gastrointestinal stromal tumors with malignant potential. J Gastrointest Surg. 2005;9:418-29 pubmed
	Bywater M, Burkhart D, Straube J, Sabò A, Pendino V, Hudson J, et al. Reactivation of Myc transcription in the mouse heart unlocks its proliferative capacity. Nat Commun. 2020;11:1827 pubmed publisher
	Tokuo H, Bhawan J, Coluccio L. Myosin X is required for efficient melanoblast migration and melanoma initiation and metastasis. Sci Rep. 2018;8:10449 pubmed publisher
	Eriksson Y, Boström M, Sandelius Å, Blennow K, Zetterberg H, Kuhn G, et al. The anti-asthmatic drug, montelukast, modifies the neurogenic potential in the young healthy and irradiated brain. Cell Death Dis. 2018;9:775 pubmed publisher
	Cetin S, Kir G, Yilmaz M. Thyroid Paraganglioma Diagnosed by Fine-Needle Aspiration Biopsy, Correlated With Histopathological Findings: Report of a Case. Diagn Cytopathol. 2016;44:643-7 pubmed publisher
	Sauter J, Ambaye A, Mount S. Increased utilization, verification, and clinical implications of immunocytochemistry: Experience in a northern New England hospital. Diagn Cytopathol. 2015;43:688-95 pubmed publisher
	Dagli M, Eryilmaz A, Acar A, Kulacoglu S, Akmansu H. Collagenous fibroma (desmoplastic fibroblastoma). Yonsei Med J. 2004;45:941-3 pubmed
	Bircan S, Candir O, Aydin S, Baspinar S, Bulbul M, Kapucuoglu N, et al. Synchronous primary adenocarcinoma and gastrointestinal stromal tumor in the stomach: a report of two cases. Turk J Gastroenterol. 2004;15:187-91 pubmed
	Park J, Choi S, Lee S, Min K, Yun S, Jeon H. Malignant gastrointestinal stromal tumor of the gallbladder. J Korean Med Sci. 2004;19:763-7 pubmed
	Usta U, Turkmen E, Mizrak B, Yildiz D, Güzel Z. Spindle cell lipoma in an intramuscular lipoma. Pathol Int. 2004;54:734-9 pubmed
	Kabukcuoglu F, Kabukcuoglu Y, Yilmaz B, Erdem Y, Evren I. Mazabraud's syndrome: intramuscular myxoma associated with fibrous dysplasia. Pathol Oncol Res. 2004;10:121-3 pubmed
	Fu M, Tam P, Sham M, Lui V. Embryonic development of the ganglion plexuses and the concentric layer structure of human gut: a topographical study. Anat Embryol (Berl). 2004;208:33-41 pubmed
	Kim D, Kim M, Lee J, Im J, Won Y, Yoon S, et al. Concomitant distribution shift of glial GABA transporter and S100 calcium-binding proteins in the rat retina after kainate-induced excitotoxic injury. Neurosci Lett. 2003;353:17-20 pubmed
	Cinel L, Dusmez D, Nabaei S, Taner D, Pata O. Two intraligamentary lipomatous tumors with immunohistochemical features. Acta Obstet Gynecol Scand. 2002;81:786-7 pubmed

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image 1 :

product information

Product Type :

Antibody

Product Name :

S100 Monoclonal Antibody (4C4.9)

Catalog # :

MA5-12969

Quantity :

500 µL

Price :

US 345.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Bovine, Human, Mouse

Applications :

Immunocytochemistry: 1:10-1:100, Immunohistochemistry (Paraffin): 1:100, Western Blot: 1:100-1:1,000

Species :

Bovine, Human, Mouse

Clone :

4C4.9

Isotype :

IgG2a

Storage :

4° C

Description :

S100 belongs to the family of calcium binding proteins such as calmodulin and troponin C. S100A is composed of an alpha and beta chain whereas S100B is composed of two beta chains. S100 protein is also expressed in the antigen presenting cells such as the Langerhans cells in skin and interdigitating reticulum cells in the paracortex of lymph nodes.

Immunogen :

Purified bovine brain S100 protein

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:10-1:100, Immunohistochemistry (Paraffin): 1:100, Western Blot: 1:100-1:1,000

Aliases :

AI266795; AI850290; Bpb; hypothetical protein LOC525716; NEF; Protein S100-A1; protein S100-B; S 100; S100; S100 alpha; S100 calcium binding protein A1; S100 calcium binding protein B; S100 calcium-binding protein A1; S100 calcium-binding protein B; S100 calcium-binding protein beta (neural); S100 calcium-binding protein, beta (neural); S-100 calcium-binding protein, beta chain; S-100 protein alpha chain; S-100 protein beta chain; S-100 protein subunit alpha; S-100 protein subunit beta; S100 protein, alpha polypeptide; S100 protein, beta polypeptide; S100 protein, beta polypeptide, neural; S100a; S100A1; S100alpha; S100-alpha; S100B; S100-B; S100beta; S100P

more info or order :

Invitrogen product webpage