Published Application/Species/Sample/Dilution | Reference |
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- western blot knockout validation; human; loading ...; fig 5e
| Pettinato A, Yoo D, VanOudenhove J, Chen Y, Cohn R, Ladha F, et al. Sarcomere function activates a p53-dependent DNA damage response that promotes polyploidization and limits in vivo cell engraftment. Cell Rep. 2021;35:109088 pubmed publisher
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- immunohistochemistry; mouse; 1:200; loading ...; fig 2e
| Cui M, Atmanli A, Morales M, Tan W, Chen K, Xiao X, et al. Nrf1 promotes heart regeneration and repair by regulating proteostasis and redox balance. Nat Commun. 2021;12:5270 pubmed publisher
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- immunocytochemistry; mouse; 1:1000; loading ...; fig 3g
| Qian B, Wang P, Zhang D, Wu L. m6A modification promotes miR-133a repression during cardiac development and hypertrophy via IGF2BP2. Cell Death Discov. 2021;7:157 pubmed publisher
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- immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 1a
| Zheng F, Chen Z, Tang Q, Wang X, Chong D, Zhang T, et al. Cholesterol metabolic enzyme Ggpps regulates epicardium development and ventricular wall architecture integrity in mice. J Mol Cell Biol. 2021;13:445-454 pubmed publisher
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- immunocytochemistry; human; fig s7
| Royer Pokora B, Busch M, Tenbusch S, Schmidt M, Beier M, Woods A, et al. Comprehensive Biology and Genetics Compendium of Wilms Tumor Cell Lines with Different WT1 Mutations. Cancers (Basel). 2020;13: pubmed publisher
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- immunocytochemistry; mouse; loading ...; fig 1c
| Yoshida S, Miyagawa S, Toyofuku T, Fukushima S, Kawamura T, Kawamura A, et al. Syngeneic Mesenchymal Stem Cells Reduce Immune Rejection After Induced Pluripotent Stem Cell-Derived Allogeneic Cardiomyocyte Transplantation. Sci Rep. 2020;10:4593 pubmed publisher
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- immunohistochemistry - paraffin section; human; loading ...; fig 2b
- immunohistochemistry - paraffin section; mouse; loading ...; fig e3a
| Aghajanian H, Kimura T, Rurik J, Hancock A, Leibowitz M, Li L, et al. Targeting cardiac fibrosis with engineered T cells. Nature. 2019;573:430-433 pubmed publisher
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- immunocytochemistry; human; 1:1000; loading ...; fig 2a
| Tsai S, Ghazizadeh Z, Wang H, Ortega F, Badieyan Z, Hsu Z, et al. A Human Embryonic Stem Cell Reporter Line for Monitoring Chemical-induced Cardiotoxicity. Cardiovasc Res. 2019;: pubmed publisher
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- flow cytometry; human; 1:200; loading ...; fig s3e, s3g
- immunocytochemistry; human; 1:200; fig s3c
- immunohistochemistry; human; 1:100; loading ...; fig 4e
| Yap L, Wang J, Moreno Moral A, Chong L, Sun Y, Harmston N, et al. In Vivo Generation of Post-infarct Human Cardiac Muscle by Laminin-Promoted Cardiovascular Progenitors. Cell Rep. 2019;26:3231-3245.e9 pubmed publisher
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- immunohistochemistry - frozen section; human; 1:100; loading ...; fig s2a
- immunocytochemistry; human; 1:100; loading ...; fig 2f
| Sahara M, Santoro F, Sohlmér J, Zhou C, Witman N, Leung C, et al. Population and Single-Cell Analysis of Human Cardiogenesis Reveals Unique LGR5 Ventricular Progenitors in Embryonic Outflow Tract. Dev Cell. 2019;48:475-490.e7 pubmed publisher
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- immunocytochemistry; human; 1:200; loading ...; fig 3e
| Zhao Y, Rafatian N, Feric N, Cox B, Aschar Sobbi R, Wang E, et al. A Platform for Generation of Chamber-Specific Cardiac Tissues and Disease Modeling. Cell. 2019;176:913-927.e18 pubmed publisher
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- immunocytochemistry; human; fig 7c
- immunocytochemistry; mouse; fig 1c
| Mohamed T, Ang Y, Radzinsky E, Zhou P, Huang Y, Elfenbein A, et al. Regulation of Cell Cycle to Stimulate Adult Cardiomyocyte Proliferation and Cardiac Regeneration. Cell. 2018;173:104-116.e12 pubmed publisher
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- immunocytochemistry; human; 1:500; loading ...; fig 5d
| Freire A, Waghray A, Soares da Silva F, Resende T, Lee D, Pereira C, et al. Transient HES5 Activity Instructs Mesodermal Cells toward a Cardiac Fate. Stem Cell Reports. 2017;9:136-148 pubmed publisher
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| Al Maqtari T, Hong K, Vajravelu B, Moktar A, Cao P, Moore J, et al. Transcription factor-induced activation of cardiac gene expression in human c-kit+ cardiac progenitor cells. PLoS ONE. 2017;12:e0174242 pubmed publisher
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- immunocytochemistry; mouse; 1:400; loading ...; fig 1e
| Abad M, Hashimoto H, Zhou H, Morales M, Chen B, Bassel Duby R, et al. Notch Inhibition Enhances Cardiac Reprogramming by Increasing MEF2C Transcriptional Activity. Stem Cell Reports. 2017;8:548-560 pubmed publisher
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- immunohistochemistry - frozen section; mouse; loading ...; fig 2a
| Hirai M, Arita Y, McGlade C, Lee K, Chen J, Evans S. Adaptor proteins NUMB and NUMBL promote cell cycle withdrawal by targeting ERBB2 for degradation. J Clin Invest. 2017;127:569-582 pubmed publisher
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- flow cytometry; human; loading ...; fig 2a
- immunocytochemistry; human; loading ...; fig s2a
| Ang Y, Rivas R, Ribeiro A, Srivas R, Rivera J, Stone N, et al. Disease Model of GATA4 Mutation Reveals Transcription Factor Cooperativity in Human Cardiogenesis. Cell. 2016;167:1734-1749.e22 pubmed publisher
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- flow cytometry; human; 1:2000; loading ...; fig 6b
- immunohistochemistry - frozen section; rat; 1:100; loading ...; fig s1e
| Protze S, Liu J, Nussinovitch U, Ohana L, Backx P, Gepstein L, et al. Sinoatrial node cardiomyocytes derived from human pluripotent cells function as a biological pacemaker. Nat Biotechnol. 2017;35:56-68 pubmed publisher
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- flow cytometry; human; 1:200; fig 1d
| Kempf H, Olmer R, Haase A, Franke A, Bolesani E, Schwanke K, et al. Bulk cell density and Wnt/TGFbeta signalling regulate mesendodermal patterning of human pluripotent stem cells. Nat Commun. 2016;7:13602 pubmed publisher
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- immunohistochemistry; mouse; loading ...
| Ma H, Wang L, Liu J, Qian L. Direct Cardiac Reprogramming as a Novel Therapeutic Strategy for Treatment of Myocardial Infarction. Methods Mol Biol. 2017;1521:69-88 pubmed
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- immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 5e
| Monnerat G, Alarcón M, Vasconcellos L, Hochman Mendez C, Brasil G, Bassani R, et al. Macrophage-dependent IL-1β production induces cardiac arrhythmias in diabetic mice. Nat Commun. 2016;7:13344 pubmed publisher
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- flow cytometry; human; loading ...; fig s3a
- immunocytochemistry; human; loading ...; fig s3a
| Zeltner N, Fattahi F, Dubois N, Saurat N, Lafaille F, Shang L, et al. Capturing the biology of disease severity in a PSC-based model of familial dysautonomia. Nat Med. 2016;22:1421-1427 pubmed publisher
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- immunohistochemistry - paraffin section; mouse; loading ...; fig 4c
| Zhou L, Dai H, Wu J, Zhou M, Yuan H, Du J, et al. Role of FEN1 S187 phosphorylation in counteracting oxygen-induced stress and regulating postnatal heart development. FASEB J. 2017;31:132-147 pubmed publisher
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- immunocytochemistry; human; 1:200; fig s1
| Okata S, Yuasa S, Suzuki T, Ito S, Makita N, Yoshida T, et al. Embryonic type Na+ channel ?-subunit, SCN3B masks the disease phenotype of Brugada syndrome. Sci Rep. 2016;6:34198 pubmed publisher
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- flow cytometry; human; fig 1d
- immunocytochemistry; human; 1:100; fig 2a
| Josowitz R, Mulero Navarro S, Rodriguez N, Falce C, Cohen N, Ullian E, et al. Autonomous and Non-autonomous Defects Underlie Hypertrophic Cardiomyopathy in BRAF-Mutant hiPSC-Derived Cardiomyocytes. Stem Cell Reports. 2016;7:355-369 pubmed publisher
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- immunocytochemistry; mouse; 1:200; loading ...; fig 2a
| Hofbauer P, Jung J, McArdle T, Ogle B. Simple Monolayer Differentiation of Murine Cardiomyocytes via Nutrient Deprivation-Mediated Activation of β-Catenin. Stem Cell Rev. 2016;12:731-743 pubmed
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- western blot; human; fig 1
| Elhamine F, Iorga B, Kruger M, Hunger M, Eckhardt J, Sreeram N, et al. Postnatal Development of Right Ventricular Myofibrillar Biomechanics in Relation to the Sarcomeric Protein Phenotype in Pediatric Patients with Conotruncal Heart Defects. J Am Heart Assoc. 2016;5: pubmed publisher
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- immunocytochemistry; mouse; 1:100; loading ...; fig 1e
| Chiapparo G, Lin X, Lescroart F, Chabab S, Paulissen C, Pitisci L, et al. Mesp1 controls the speed, polarity, and directionality of cardiovascular progenitor migration. J Cell Biol. 2016;213:463-77 pubmed publisher
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- immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 2h
| Nakamura R, Koshiba Takeuchi K, Tsuchiya M, Kojima M, Miyazawa A, Ito K, et al. Expression analysis of Baf60c during heart regeneration in axolotls and neonatal mice. Dev Growth Differ. 2016;58:367-82 pubmed publisher
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- flow cytometry; human; 1:200; fig 4
- immunocytochemistry; human; 1:200
| Titmarsh D, Glass N, Mills R, Hidalgo A, Wolvetang E, Porrello E, et al. Induction of Human iPSC-Derived Cardiomyocyte Proliferation Revealed by Combinatorial Screening in High Density Microbioreactor Arrays. Sci Rep. 2016;6:24637 pubmed publisher
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- immunocytochemistry; human; 1:200; fig 1
| Burridge P, Li Y, Matsa E, Wu H, Ong S, Sharma A, et al. Human induced pluripotent stem cell-derived cardiomyocytes recapitulate the predilection of breast cancer patients to doxorubicin-induced cardiotoxicity. Nat Med. 2016;22:547-56 pubmed publisher
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- immunocytochemistry; mouse; 1:1000; fig 8
| Langer D, Martianov I, Alpern D, Rhinn M, Keime C, Dolle P, et al. Essential role of the TFIID subunit TAF4 in murine embryogenesis and embryonic stem cell differentiation. Nat Commun. 2016;7:11063 pubmed publisher
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- immunocytochemistry; mouse; 1:400; fig 4
| Fischer K, Morgan K, Hearon K, Sklaviadis D, Tochka Z, Fenton O, et al. Poly(Limonene Thioether) Scaffold for Tissue Engineering. Adv Healthc Mater. 2016;5:813-21 pubmed publisher
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- immunohistochemistry - frozen section; mouse; fig 2
| Passer D, van de Vrugt A, Atmanli A, Domian I. Atypical Protein Kinase C-Dependent Polarized Cell Division Is Required for Myocardial Trabeculation. Cell Rep. 2016;14:1662-1672 pubmed publisher
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- immunocytochemistry; mouse; 1:200; fig s2f
| Fuchs C, Gawlas S, Heher P, Nikouli S, Paar H, Ivankovic M, et al. Desmin enters the nucleus of cardiac stem cells and modulates Nkx2.5 expression by participating in transcription factor complexes that interact with the nkx2.5 gene. Biol Open. 2016;5:140-53 pubmed publisher
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- flow cytometry; human; fig s1
| Eng G, Lee B, Protas L, Gagliardi M, Brown K, Kass R, et al. Autonomous beating rate adaptation in human stem cell-derived cardiomyocytes. Nat Commun. 2016;7:10312 pubmed publisher
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- immunocytochemistry; mouse; 1:200; fig s2
| Jung J, Hu D, Domian I, Ogle B. An integrated statistical model for enhanced murine cardiomyocyte differentiation via optimized engagement of 3D extracellular matrices. Sci Rep. 2015;5:18705 pubmed publisher
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- flow cytometry; mouse; fig 2
- immunocytochemistry; mouse; 1:100; fig 4
| Ban K, Wile B, Cho K, Kim S, Song M, Kim S, et al. Non-genetic Purification of Ventricular Cardiomyocytes from Differentiating Embryonic Stem Cells through Molecular Beacons Targeting IRX-4. Stem Cell Reports. 2015;5:1239-1249 pubmed publisher
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- flow cytometry; human; 1:200; fig 3
| Busser B, Lin Y, Yang Y, Zhu J, Chen G, Michelson A. An Orthologous Epigenetic Gene Expression Signature Derived from Differentiating Embryonic Stem Cells Identifies Regulators of Cardiogenesis. PLoS ONE. 2015;10:e0141066 pubmed publisher
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- flow cytometry; mouse; 1:200; fig 2
- immunocytochemistry; mouse; 1:500; fig 2
| Zhao Y, Londono P, Cao Y, Sharpe E, Proenza C, O Rourke R, et al. High-efficiency reprogramming of fibroblasts into cardiomyocytes requires suppression of pro-fibrotic signalling. Nat Commun. 2015;6:8243 pubmed publisher
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- immunohistochemistry - frozen section; mouse; 1:350; fig 1b
| Kimura W, Xiao F, Canseco D, Muralidhar S, Thet S, Zhang H, et al. Hypoxia fate mapping identifies cycling cardiomyocytes in the adult heart. Nature. 2015;523:226-30 pubmed publisher
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| Szabo L, Morey R, Palpant N, Wang P, Afari N, Jiang C, et al. Statistically based splicing detection reveals neural enrichment and tissue-specific induction of circular RNA during human fetal development. Genome Biol. 2015;16:126 pubmed publisher
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- immunocytochemistry; mouse; 1:500; fig 2
| Zhu S, Wang H, Ding S. Reprogramming fibroblasts toward cardiomyocytes, neural stem cells and hepatocytes by cell activation and signaling-directed lineage conversion. Nat Protoc. 2015;10:959-73 pubmed publisher
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- immunocytochemistry; mouse; 1:500; fig 2
| Tsai S, Maass K, Lu J, Fishman G, Chen S, Evans T. Efficient Generation of Cardiac Purkinje Cells from ESCs by Activating cAMP Signaling. Stem Cell Reports. 2015;4:1089-102 pubmed publisher
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- immunocytochemistry; human; 1:100; fig 2
- western blot; human; 1:500; fig 5
| Zatti S, Martewicz S, Serena E, Uno N, Giobbe G, Kazuki Y, et al. Complete restoration of multiple dystrophin isoforms in genetically corrected Duchenne muscular dystrophy patient-derived cardiomyocytes. Mol Ther Methods Clin Dev. 2014;1:1 pubmed publisher
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- immunocytochemistry; human; 1:400; fig 6
| Palpant N, Hofsteen P, Pabon L, Reinecke H, Murry C. Cardiac development in zebrafish and human embryonic stem cells is inhibited by exposure to tobacco cigarettes and e-cigarettes. PLoS ONE. 2015;10:e0126259 pubmed publisher
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| Quan C, Xie B, Wang H, Chen S. PKB-Mediated Thr649 Phosphorylation of AS160/TBC1D4 Regulates the R-Wave Amplitude in the Heart. PLoS ONE. 2015;10:e0124491 pubmed publisher
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- western blot; mouse; 1:100; fig 1
| Alexander J, Hota S, He D, Thomas S, Ho L, Pennacchio L, et al. Brg1 modulates enhancer activation in mesoderm lineage commitment. Development. 2015;142:1418-30 pubmed publisher
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| Kim M, Horst A, Blinka S, Stamm K, Mahnke D, Schuman J, et al. Activin-A and Bmp4 levels modulate cell type specification during CHIR-induced cardiomyogenesis. PLoS ONE. 2015;10:e0118670 pubmed publisher
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- immunocytochemistry; mouse; 1:400; fig 1e
| Choi S, Lee H, Choi J, Kim J, Park C, Joo H, et al. Cyclosporin A induces cardiac differentiation but inhibits hemato-endothelial differentiation of P19 cells. PLoS ONE. 2015;10:e0117410 pubmed publisher
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- flow cytometry; human; 1:1000
| van den Berg C, Elliott D, Braam S, Mummery C, Davis R. Differentiation of Human Pluripotent Stem Cells to Cardiomyocytes Under Defined Conditions. Methods Mol Biol. 2016;1353:163-80 pubmed publisher
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- immunohistochemistry - paraffin section; human; 1:100; fig 3
- western blot; human; fig s1
| Clarke J, Lyra e Silva N, Figueiredo C, Frozza R, Ledo J, Beckman D, et al. Alzheimer-associated Aβ oligomers impact the central nervous system to induce peripheral metabolic deregulation. EMBO Mol Med. 2015;7:190-210 pubmed publisher
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- immunocytochemistry; human; 1:200
| Lewis K, Silvester N, Barberini Jammaers S, Mason S, Marsh S, Lipka M, et al. A new system for profiling drug-induced calcium signal perturbation in human embryonic stem cell-derived cardiomyocytes. J Biomol Screen. 2015;20:330-40 pubmed publisher
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- immunocytochemistry; mouse; 1:400; fig 3
| Nam Y, Lubczyk C, Bhakta M, Zang T, Fernandez Perez A, McAnally J, et al. Induction of diverse cardiac cell types by reprogramming fibroblasts with cardiac transcription factors. Development. 2014;141:4267-78 pubmed publisher
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- immunohistochemistry; human; 1:150; fig 4
| Tchao J, Han L, Lin B, Yang L, Tobita K. Combined biophysical and soluble factor modulation induces cardiomyocyte differentiation from human muscle derived stem cells. Sci Rep. 2014;4:6614 pubmed publisher
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- immunohistochemistry - frozen section; mouse; 1:100
| Kim E, Shekhar A, Lu J, Lin X, Liu F, Zhang J, et al. PCP4 regulates Purkinje cell excitability and cardiac rhythmicity. J Clin Invest. 2014;124:5027-36 pubmed publisher
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- immunocytochemistry; mouse; 1:100; fig 4
| Wile B, Ban K, Yoon Y, Bao G. Molecular beacon-enabled purification of living cells by targeting cell type-specific mRNAs. Nat Protoc. 2014;9:2411-24 pubmed publisher
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- flow cytometry; human; 1:100
- immunocytochemistry; human; 1:100
| Josowitz R, Lu J, Falce C, D Souza S, Wu M, Cohen N, et al. Identification and purification of human induced pluripotent stem cell-derived atrial-like cardiomyocytes based on sarcolipin expression. PLoS ONE. 2014;9:e101316 pubmed publisher
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- flow cytometry; human; 1:200
- immunocytochemistry; human; 1:200
| Burridge P, Matsa E, Shukla P, Lin Z, Churko J, Ebert A, et al. Chemically defined generation of human cardiomyocytes. Nat Methods. 2014;11:855-60 pubmed publisher
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- flow cytometry; mouse; 0.25 ug/ml
| Xie Y, Ibrahim A, Cheng K, Wu Z, Liang W, Malliaras K, et al. Importance of cell-cell contact in the therapeutic benefits of cardiosphere-derived cells. Stem Cells. 2014;32:2397-406 pubmed publisher
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- immunohistochemistry; mouse; 1:100
- western blot; mouse; 1:10,000
| Puente B, Kimura W, Muralidhar S, Moon J, Amatruda J, Phelps K, et al. The oxygen-rich postnatal environment induces cardiomyocyte cell-cycle arrest through DNA damage response. Cell. 2014;157:565-79 pubmed publisher
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- immunocytochemistry; mouse; fig 4
| Kowno M, Watanabe Susaki K, Ishimine H, Komazaki S, Enomoto K, Seki Y, et al. Prohibitin 2 regulates the proliferation and lineage-specific differentiation of mouse embryonic stem cells in mitochondria. PLoS ONE. 2014;9:e81552 pubmed publisher
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- flow cytometry; mouse
- immunocytochemistry; mouse
| Cho S, Park J, Heo H, Park S, Song S, Kim I, et al. Dual modulation of the mitochondrial permeability transition pore and redox signaling synergistically promotes cardiomyocyte differentiation from pluripotent stem cells. J Am Heart Assoc. 2014;3:e000693 pubmed publisher
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- flow cytometry; mouse; 1:500
| Shenje L, Andersen P, Halushka M, Lui C, Fernandez L, Collin G, et al. Mutations in Alström protein impair terminal differentiation of cardiomyocytes. Nat Commun. 2014;5:3416 pubmed publisher
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- immunocytochemistry; mouse; 1:200
| Ifkovits J, Addis R, Epstein J, Gearhart J. Inhibition of TGF? signaling increases direct conversion of fibroblasts to induced cardiomyocytes. PLoS ONE. 2014;9:e89678 pubmed publisher
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- flow cytometry; mouse; 1:100
| Engels M, Rajarajan K, Feistritzer R, Sharma A, Nielsen U, Schalij M, et al. Insulin-like growth factor promotes cardiac lineage induction in vitro by selective expansion of early mesoderm. Stem Cells. 2014;32:1493-502 pubmed publisher
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- immunohistochemistry; mouse; 1:200
| Heallen T, Morikawa Y, Leach J, Tao G, Willerson J, Johnson R, et al. Hippo signaling impedes adult heart regeneration. Development. 2013;140:4683-90 pubmed publisher
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- immunohistochemistry; zebrafish ; 1:100
| Chen C, Durand E, Wang J, Zon L, Poss K. zebraflash transgenic lines for in vivo bioluminescence imaging of stem cells and regeneration in adult zebrafish. Development. 2013;140:4988-97 pubmed publisher
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- immunohistochemistry - paraffin section; human; 1:100
| Turnbull I, Karakikes I, Serrao G, Backeris P, Lee J, Xie C, et al. Advancing functional engineered cardiac tissues toward a preclinical model of human myocardium. FASEB J. 2014;28:644-54 pubmed publisher
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- immunohistochemistry; mouse; 1:500; fig 6
| Maejima Y, Kyoi S, Zhai P, Liu T, Li H, Ivessa A, et al. Mst1 inhibits autophagy by promoting the interaction between Beclin1 and Bcl-2. Nat Med. 2013;19:1478-88 pubmed publisher
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- immunohistochemistry; mouse; 1:250
| Nelson D, Jin D, Downs K, Kamp T, Lyons G. Irx4 identifies a chamber-specific cell population that contributes to ventricular myocardium development. Dev Dyn. 2014;243:381-92 pubmed
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- immunocytochemistry; mouse; 1:10
- immunohistochemistry; mouse; 1:200
| Später D, Abramczuk M, Buac K, Zangi L, Stachel M, Clarke J, et al. A HCN4+ cardiomyogenic progenitor derived from the first heart field and human pluripotent stem cells. Nat Cell Biol. 2013;15:1098-106 pubmed publisher
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- immunocytochemistry; mouse; 1:1000
| Lehmann M, Nguemo F, Wagh V, Pfannkuche K, Hescheler J, Reppel M. Evidence for a critical role of catecholamines for cardiomyocyte lineage commitment in murine embryonic stem cells. PLoS ONE. 2013;8:e70913 pubmed publisher
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- immunohistochemistry; human
| Yoshioka N, Gros E, Li H, Kumar S, Deacon D, Maron C, et al. Efficient generation of human iPSCs by a synthetic self-replicative RNA. Cell Stem Cell. 2013;13:246-54 pubmed publisher
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- immunohistochemistry; human
| Zhang W, Liu X, Yang L, Zhu D, Zhang Y, Chen Y, et al. Wharton's jelly-derived mesenchymal stem cells promote myocardial regeneration and cardiac repair after miniswine acute myocardial infarction. Coron Artery Dis. 2013;24:549-58 pubmed publisher
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- immunohistochemistry; mouse; 1:200
| Rebuzzini P, Fassina L, Mulas F, Bellazzi R, Redi C, Di Liberto R, et al. Mouse embryonic stem cells irradiated with ?-rays differentiate into cardiomyocytes but with altered contractile properties. Mutat Res. 2013;756:37-45 pubmed publisher
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- immunohistochemistry; mouse
| Liang X, Wang G, Lin L, Lowe J, Zhang Q, Bu L, et al. HCN4 dynamically marks the first heart field and conduction system precursors. Circ Res. 2013;113:399-407 pubmed publisher
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- immunocytochemistry; mouse
| Craft A, Ahmed N, Rockel J, Baht G, Alman B, Kandel R, et al. Specification of chondrocytes and cartilage tissues from embryonic stem cells. Development. 2013;140:2597-610 pubmed publisher
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- immunohistochemistry; human
| Duerr G, Heinemann J, Dunkel S, Zimmer A, Lutz B, Lerner R, et al. Myocardial hypertrophy is associated with inflammation and activation of endocannabinoid system in patients with aortic valve stenosis. Life Sci. 2013;92:976-83 pubmed publisher
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- immunocytochemistry; rat; 1:100; fig 2
| Hadad I, Veithen A, Springael J, Sotiropoulou P, Mendes Da Costa A, Miot F, et al. Stroma cell-derived factor-1? signaling enhances calcium transients and beating frequency in rat neonatal cardiomyocytes. PLoS ONE. 2013;8:e56007 pubmed publisher
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- immunohistochemistry; mouse; 1:100
| Haenebalcke L, Goossens S, Dierickx P, Bartunkova S, D Hont J, Haigh K, et al. The ROSA26-iPSC mouse: a conditional, inducible, and exchangeable resource for studying cellular (De)differentiation. Cell Rep. 2013;3:335-41 pubmed publisher
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- immunohistochemistry; mouse; 1:200
| Hoebaus J, Heher P, Gottschamel T, Scheinast M, Auner H, Walder D, et al. Embryonic stem cells facilitate the isolation of persistent clonal cardiovascular progenitor cell lines and leukemia inhibitor factor maintains their self-renewal and myocardial differentiation potential in vitro. Cells Tissues Organs. 2013;197:249-68 pubmed publisher
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- immunohistochemistry; mouse
| Del Re D, Yang Y, Nakano N, Cho J, Zhai P, Yamamoto T, et al. Yes-associated protein isoform 1 (Yap1) promotes cardiomyocyte survival and growth to protect against myocardial ischemic injury. J Biol Chem. 2013;288:3977-88 pubmed publisher
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| Brody M, Hacker T, Patel J, Feng L, Sadoshima J, Tevosian S, et al. Ablation of the cardiac-specific gene leucine-rich repeat containing 10 (Lrrc10) results in dilated cardiomyopathy. PLoS ONE. 2012;7:e51621 pubmed publisher
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- immunocytochemistry; human
| Serena E, Cimetta E, Zatti S, Zaglia T, Zagallo M, Keller G, et al. Micro-arrayed human embryonic stem cells-derived cardiomyocytes for in vitro functional assay. PLoS ONE. 2012;7:e48483 pubmed publisher
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- immunohistochemistry; zebrafish
| Opitz R, Maquet E, Huisken J, Antonica F, Trubiroha A, Pottier G, et al. Transgenic zebrafish illuminate the dynamics of thyroid morphogenesis and its relationship to cardiovascular development. Dev Biol. 2012;372:203-16 pubmed publisher
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- flow cytometry; mouse; fig 4
- immunohistochemistry; mouse; 1:500; fig 3
| Wei W, Sun H, Ting K, Zhang L, Lee H, Li G, et al. Inhibition of cardiomyocytes differentiation of mouse embryonic stem cells by CD38/cADPR/Ca2+ signaling pathway. J Biol Chem. 2012;287:35599-611 pubmed publisher
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- immunohistochemistry; hamsters
| Mastri M, Shah Z, McLaughlin T, Greene C, Baum L, Suzuki G, et al. Activation of Toll-like receptor 3 amplifies mesenchymal stem cell trophic factors and enhances therapeutic potency. Am J Physiol Cell Physiol. 2012;303:C1021-33 pubmed publisher
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- immunocytochemistry; human
| Egashira T, Yuasa S, Suzuki T, Aizawa Y, Yamakawa H, Matsuhashi T, et al. Disease characterization using LQTS-specific induced pluripotent stem cells. Cardiovasc Res. 2012;95:419-29 pubmed publisher
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- immunohistochemistry; human
| Traister A, Aafaqi S, Masse S, Dai X, Li M, Hinek A, et al. ILK induces cardiomyogenesis in the human heart. PLoS ONE. 2012;7:e37802 pubmed publisher
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- immunocytochemistry; mouse; 1:400
- immunohistochemistry; mouse; 1:400
| Song K, Nam Y, Luo X, Qi X, Tan W, Huang G, et al. Heart repair by reprogramming non-myocytes with cardiac transcription factors. Nature. 2012;485:599-604 pubmed publisher
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- flow cytometry; human; 1:200
| Hazeltine L, Simmons C, Salick M, Lian X, Badur M, Han W, et al. Effects of substrate mechanics on contractility of cardiomyocytes generated from human pluripotent stem cells. Int J Cell Biol. 2012;2012:508294 pubmed publisher
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| van den Ameele J, Tiberi L, Bondue A, Paulissen C, Herpoel A, Iacovino M, et al. Eomesodermin induces Mesp1 expression and cardiac differentiation from embryonic stem cells in the absence of Activin. EMBO Rep. 2012;13:355-62 pubmed publisher
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- western blot; human; 0.2 ug/ml
| Jung C, Moretti A, Mederos y Schnitzler M, Iop L, Storch U, Bellin M, et al. Dantrolene rescues arrhythmogenic RYR2 defect in a patient-specific stem cell model of catecholaminergic polymorphic ventricular tachycardia. EMBO Mol Med. 2012;4:180-91 pubmed publisher
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- immunohistochemistry; human
| Ng K, Chan Y, Lee Y, Lai W, Au K, Fung M, et al. Cobalt chloride pretreatment promotes cardiac differentiation of human embryonic stem cells under atmospheric oxygen level. Cell Reprogram. 2011;13:527-37 pubmed publisher
|
- flow cytometry; human; 1:400
| Dubois N, Craft A, Sharma P, Elliott D, Stanley E, Elefanty A, et al. SIRPA is a specific cell-surface marker for isolating cardiomyocytes derived from human pluripotent stem cells. Nat Biotechnol. 2011;29:1011-8 pubmed publisher
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- immunocytochemistry; mouse; 1:100
| Pieters T, Haenebalcke L, Hochepied T, D Hont J, Haigh J, van Roy F, et al. Efficient and user-friendly pluripotin-based derivation of mouse embryonic stem cells. Stem Cell Rev. 2012;8:768-78 pubmed publisher
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| Uosaki H, Fukushima H, Takeuchi A, Matsuoka S, Nakatsuji N, Yamanaka S, et al. Efficient and scalable purification of cardiomyocytes from human embryonic and induced pluripotent stem cells by VCAM1 surface expression. PLoS ONE. 2011;6:e23657 pubmed publisher
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- ELISA; domestic rabbit; 0.25 ug/ml
- ELISA; mouse; 0.25 ug/ml
| Lopez J, Myagmar B, Swigart P, Montgomery M, Haynam S, Bigos M, et al. ?-myosin heavy chain is induced by pressure overload in a minor subpopulation of smaller mouse cardiac myocytes. Circ Res. 2011;109:629-38 pubmed publisher
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| Kim E, Chen L, Ma Y, Yu W, Chang J, Moskowitz I, et al. Expression of sumoylation deficient Nkx2.5 mutant in Nkx2.5 haploinsufficient mice leads to congenital heart defects. PLoS ONE. 2011;6:e20803 pubmed publisher
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| Lee Y, Ng K, Lai W, Man C, Lieu D, Lau C, et al. Ouabain facilitates cardiac differentiation of mouse embryonic stem cells through ERK1/2 pathway. Acta Pharmacol Sin. 2011;32:52-61 pubmed publisher
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- immunocytochemistry; human; fig 6
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| Grajales L, Garcia J, Banach K, Geenen D. Delayed enrichment of mesenchymal cells promotes cardiac lineage and calcium transient development. J Mol Cell Cardiol. 2010;48:735-45 pubmed publisher
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| Moretti A, Bellin M, Jung C, Thies T, Takashima Y, Bernshausen A, et al. Mouse and human induced pluripotent stem cells as a source for multipotent Isl1+ cardiovascular progenitors. FASEB J. 2010;24:700-11 pubmed publisher
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- flow cytometry; mouse
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- immunocytochemistry; mouse; 2 ug/ml
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| Genovese J, Spadaccio C, Langer J, Habe J, Jackson J, Patel A. Electrostimulation induces cardiomyocyte predifferentiation of fibroblasts. Biochem Biophys Res Commun. 2008;370:450-5 pubmed publisher
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| Sapp V, Aguirre A, Mainkar G, Ding J, Adler E, Liao R, et al. Genome-wide CRISPR/Cas9 screening in human iPS derived cardiomyocytes uncovers novel mediators of doxorubicin cardiotoxicity. Sci Rep. 2021;11:13866 pubmed publisher
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| Garry G, Bezprozvannaya S, Chen K, Zhou H, Hashimoto H, Morales M, et al. The histone reader PHF7 cooperates with the SWI/SNF complex at cardiac super enhancers to promote direct reprogramming. Nat Cell Biol. 2021;23:467-475 pubmed publisher
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