MYOD Monoclonal Antibody (5.8A) | Invitrogen MA5-12902 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

MYOD Monoclonal Antibody (5.8A)

catalog :

MA5-12902

quantity :

500 µL

price :

US 395.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5.8A

reactivity :

human, mouse, rat, chicken

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 19

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; loading ...; fig 7b western blot; human; loading ...; fig 7a	Feng Q, Jagannathan S, Bradley R. The RNA Surveillance Factor UPF1 Represses Myogenesis via Its E3 Ubiquitin Ligase Activity. Mol Cell. 2017;67:239-251.e6 pubmed publisher
immunohistochemistry - frozen section; mouse; 1:100	Cohen T, Kollias H, Liu N, Ward C, Wagner K. Genetic disruption of Smad7 impairs skeletal muscle growth and regeneration. J Physiol. 2015;593:2479-97 pubmed publisher
immunohistochemistry; human	Deng F, Galvan K, de la Roza G, Zhang S, Souid A, Stein C. Molecular characterization of an EWSR1-POU5F1 fusion associated with a t(6;22) in an undifferentiated soft tissue sarcoma. Cancer Genet. 2011;204:423-9 pubmed publisher
immunocytochemistry; mouse western blot; mouse	Hirai H, Verma M, Watanabe S, Tastad C, Asakura Y, Asakura A. MyoD regulates apoptosis of myoblasts through microRNA-mediated down-regulation of Pax3. J Cell Biol. 2010;191:347-65 pubmed publisher
immunocytochemistry; mouse; 1:200	Fukada S, Yamamoto Y, Segawa M, Sakamoto K, Nakajima M, Sato M, et al. CD90-positive cells, an additional cell population, produce laminin alpha2 upon transplantation to dy(3k)/dy(3k) mice. Exp Cell Res. 2008;314:193-203 pubmed
immunocytochemistry; mouse; 1:200	Fukada S, Uezumi A, Ikemoto M, Masuda S, Segawa M, Tanimura N, et al. Molecular signature of quiescent satellite cells in adult skeletal muscle. Stem Cells. 2007;25:2448-59 pubmed
western blot; human; 1:500	Zhao Z, Gruszczynska Biegala J, Zolkiewska A. ADP-ribosylation of integrin alpha7 modulates the binding of integrin alpha7beta1 to laminin. Biochem J. 2005;385:309-17 pubmed
	Wright W, Li C, Zheng C, Tucker H. FOXP1 Interacts with MyoD to Repress its Transcription and Myoblast Conversion. J Cell Signal. 2021;2:9-26 pubmed
	Gerhart J, Gugerty L, Lecker P, Abdalla F, Martin M, Gerhart O, et al. Myo/Nog cells are nonprofessional phagocytes. PLoS ONE. 2020;15:e0235898 pubmed publisher
	Gerhart J, Bowers J, Gugerty L, Gerhart C, Martin M, Abdalla F, et al. Brain-specific angiogenesis inhibitor 1 is expressed in the Myo/Nog cell lineage. PLoS ONE. 2020;15:e0234792 pubmed publisher
	Gerhart J, Behling K, Paessler M, Milton L, Bramblett G, GARCIA D, et al. Rhabdomyosarcoma and Wilms tumors contain a subpopulation of noggin producing, myogenic cells immunoreactive for lens beaded filament proteins. PLoS ONE. 2019;14:e0214758 pubmed publisher
	Lim C, Ling K, Cheah P. Isolation, cultivation and immunostaining of single myofibers: An improved approach to study the behavior of satellite cells. J Biol Methods. 2018;5:e87 pubmed publisher
	Onodera Y, Teramura T, Takehara T, Itokazu M, Mori T, Fukuda K. Inflammation-associated miR-155 activates differentiation of muscular satellite cells. PLoS ONE. 2018;13:e0204860 pubmed publisher
	Kendall G, Watson S, Xu L, LaVigne C, Murchison W, Rakheja D, et al. PAX3-FOXO1 transgenic zebrafish models identify HES3 as a mediator of rhabdomyosarcoma tumorigenesis. elife. 2018;7: pubmed publisher
	Pumberger M, Qazi T, Ehrentraut M, Textor M, Kueper J, Stoltenburg Didinger G, et al. Synthetic niche to modulate regenerative potential of MSCs and enhance skeletal muscle regeneration. Biomaterials. 2016;99:95-108 pubmed publisher
	Gorbe A, Becker D, Dux L, Stelkovics E, Krenacs L, Bagdi E, et al. Transient upregulation of connexin43 gap junctions and synchronized cell cycle control precede myoblast fusion in regenerating skeletal muscle in vivo. Histochem Cell Biol. 2005;123:573-83 pubmed
	Cao Y, Zhao Z, Gruszczynska Biegala J, Zolkiewska A. Role of metalloprotease disintegrin ADAM12 in determination of quiescent reserve cells during myogenic differentiation in vitro. Mol Cell Biol. 2003;23:6725-38 pubmed
	Holst D, Luquet S, Kristiansen K, Grimaldi P. Roles of peroxisome proliferator-activated receptors delta and gamma in myoblast transdifferentiation. Exp Cell Res. 2003;288:168-76 pubmed
	Dedkov E, Kostrominova T, Borisov A, Carlson B. MyoD and myogenin protein expression in skeletal muscles of senile rats. Cell Tissue Res. 2003;311:401-16 pubmed

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product information

Product Type :

Antibody

Product Name :

MYOD Monoclonal Antibody (5.8A)

Catalog # :

MA5-12902

Quantity :

500 µL

Price :

US 395.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Chicken, Human, Mouse, Rat

Applications :

Immunocytochemistry: 2-3 µg/mL, Immunomicroscopy: Assay-dependent, Immunoprecipitation: 2 µg/mL, Western Blot: 2-3 µg/mL

Species :

Chicken, Human, Mouse, Rat

Clone :

5.8A

Isotype :

IgG1, kappa

Storage :

4° C

Description :

The Myogenic determination gene (MyoD) was first identified by the virtue of its ability to convert embryonic mouse fibroblast cells to muscle cells. It was subsequently shown that forced expression of MyoD (human homolog is myf 3) gene in a wide variety of normal and neoplastic cells could either convert the cells to muscle cells or activate a set of the otherwise transcriptionally inactive muscle-specific genes in these cells. The regulatory domain of the MyoD gene product lies within a 70 amino acid region and comprises a basic DNA binding motif and a helix-loop-helix (HLH) dimerization motif. Subsequent studies identified three other genes whose products shared sequence homology for the basic HLH domain of MyoD. These are; myf5, myogenin (human homolog is myf4) and myf6 (also known as MRF4 and herculin).

Immunogen :

Recombinant mouse MyoD1 protein

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 2-3 µg/mL, Immunomicroscopy: Assay-dependent, Immunoprecipitation: 2 µg/mL, Western Blot: 2-3 µg/mL

Aliases :

AI503393; bHLHc1; Class C basic helix-loop-helix protein 1; CMD1; MYF3; Myf-3; Myoblast determination protein 1; myoblast determination protein 1 homolog; Myod; MYOD1; Myod-1; MYOD1 homolog; myogenic differentiation 1; myogenic factor 1; myogenic factor 3; PUM; unnamed protein product

more info or order :

Invitrogen product webpage