| Published Application/Species/Sample/Dilution | Reference |
|---|
- immunohistochemistry - paraffin section; human; loading ...; fig 2b
| Yurugi H, Marini F, Weber C, David K, Zhao Q, Binder H, et al. Targeting prohibitins with chemical ligands inhibits KRAS-mediated lung tumours. Oncogene. 2017;36:4778-4789 pubmed publisher |
- western blot; human; loading ...; fig 2c
| Zaganelli S, Rebelo Guiomar P, Maundrell K, Rozanska A, Pierredon S, Powell C, et al. The Pseudouridine Synthase RPUSD4 Is an Essential Component of Mitochondrial RNA Granules. J Biol Chem. 2017;292:4519-4532 pubmed publisher |
- western blot; human; loading ...; fig 2b
| Diaz Hidalgo L, Altuntas S, Rossin F, D Eletto M, Marsella C, Farrace M, et al. Transglutaminase type 2-dependent selective recruitment of proteins into exosomes under stressful cellular conditions. Biochim Biophys Acta. 2016;1863:2084-92 pubmed publisher |
- western blot; rat; 1:250; fig 5a
| Poitelon Y, Bogni S, Matafora V, Della Flora Nunes G, Hurley E, Ghidinelli M, et al. Spatial mapping of juxtacrine axo-glial interactions identifies novel molecules in peripheral myelination. Nat Commun. 2015;6:8303 pubmed publisher |
- western blot; pigs ; 1:100
| Rogée S, Le Gall M, Chafey P, Bouquet J, Cordonnier N, Frederici C, et al. Quantitative proteomics identifies host factors modulated during acute hepatitis E virus infection in the swine model. J Virol. 2015;89:129-43 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:100
| Leal M, Cirilo P, Mazzotti T, Calcagno D, Wisnieski F, Demachki S, et al. Prohibitin expression deregulation in gastric cancer is associated with the 3' untranslated region 1630 C>T polymorphism and copy number variation. PLoS ONE. 2014;9:e98583 pubmed publisher |
| Wang Y, Guo X, Li S, Zhao Y, Liu Z, Lee W, et al. Prohibitin is involved in the activated internalization and degradation of protease-activated receptor 1. Biochim Biophys Acta. 2014;1843:1393-401 pubmed publisher |
- immunoprecipitation; human
- western blot; human; 1:400
| Begum A, Lin Q, Yu C, Kim Y, Yun Z. Interaction of delta-like 1 homolog (Drosophila) with prohibitins and its impact on tumor cell clonogenicity. Mol Cancer Res. 2014;12:155-64 pubmed publisher |
| Panico K, Forti F. Proteomic, cellular, and network analyses reveal new DUSP3 interactions with nucleolar proteins in HeLa cells. J Proteome Res. 2013;12:5851-66 pubmed publisher |
- flow cytometry; human; 1:100
- immunohistochemistry; human; 1:100
- western blot; human; 1:500
| Jiang P, Xiang Y, Wang Y, Li S, Wang Y, Hua H, et al. Differential expression and subcellular localization of Prohibitin 1 are related to tumorigenesis and progression of non-small cell lung cancer. Int J Clin Exp Pathol. 2013;6:2092-101 pubmed |
| Yurugi H, Tanida S, Akita K, Ishida A, Toda M, Nakada H. Prohibitins function as endogenous ligands for Siglec-9 and negatively regulate TCR signaling upon ligation. Biochem Biophys Res Commun. 2013;434:376-81 pubmed publisher |
| Jourdain A, Koppen M, Wydro M, Rodley C, Lightowlers R, Chrzanowska Lightowlers Z, et al. GRSF1 regulates RNA processing in mitochondrial RNA granules. Cell Metab. 2013;17:399-410 pubmed publisher |
- immunocytochemistry; human; 1:50
| Picard C, Pellicelli M, Taheri M, Lavoie J, Doucet R, Wang D, et al. Nuclear accumulation of prohibitin 1 in osteoarthritic chondrocytes down-regulates PITX1 expression. Arthritis Rheum. 2013;65:993-1003 pubmed publisher |
| Leanza L, Zoratti M, Gulbins E, Szabo I. Induction of apoptosis in macrophages via Kv1.3 and Kv1.5 potassium channels. Curr Med Chem. 2012;19:5394-404 pubmed |
- western blot; human; 1:1000
| Quast S, Berger A, Buttstädt N, Friebel K, Schönherr R, Eberle J. General Sensitization of melanoma cells for TRAIL-induced apoptosis by the potassium channel inhibitor TRAM-34 depends on release of SMAC. PLoS ONE. 2012;7:e39290 pubmed publisher |
- western blot; human; 1:1000
| Fletcher C, Dart D, Sita Lumsden A, Cheng H, Rennie P, Bevan C. Androgen-regulated processing of the oncomir miR-27a, which targets Prohibitin in prostate cancer. Hum Mol Genet. 2012;21:3112-27 pubmed publisher |
| Leanza L, Henry B, Sassi N, Zoratti M, Chandy K, Gulbins E, et al. Inhibitors of mitochondrial Kv1.3 channels induce Bax/Bak-independent death of cancer cells. EMBO Mol Med. 2012;4:577-93 pubmed publisher |
- immunohistochemistry; rat; 1:300
| Zhou T, Qin Y, Li Z, Xu H, Zhao Y, Lei F. All-trans retinoic acid treatment is associated with prohibitin expression in renal interstitial fibrosis rats. Int J Mol Sci. 2012;13:2769-82 pubmed publisher |
| Kamiński M, Roth D, Sass S, Sauer S, Krammer P, Gülow K. Manganese superoxide dismutase: a regulator of T cell activation-induced oxidative signaling and cell death. Biochim Biophys Acta. 2012;1823:1041-52 pubmed publisher |
| Yurugi H, Tanida S, Ishida A, Akita K, Toda M, Inoue M, et al. Expression of prohibitins on the surface of activated T cells. Biochem Biophys Res Commun. 2012;420:275-80 pubmed publisher |
| Orr S, Boutz D, Wang R, Chronis C, Lea N, Thayaparan T, et al. Proteomic and protein interaction network analysis of human T lymphocytes during cell-cycle entry. Mol Syst Biol. 2012;8:573 pubmed publisher |
| Masgras I, Rasola A, Bernardi P. Induction of the permeability transition pore in cells depleted of mitochondrial DNA. Biochim Biophys Acta. 2012;1817:1860-6 pubmed publisher |
- western blot; human; 1:2000
| Sofiadis A, Becker S, Hellman U, Hultin Rosenberg L, Dinets A, Hulchiy M, et al. Proteomic profiling of follicular and papillary thyroid tumors. Eur J Endocrinol. 2012;166:657-67 pubmed publisher |
- immunocytochemistry; human
- western blot; human; 1:1000
| Dart D, Brooke G, Sita Lumsden A, Waxman J, Bevan C. Reducing prohibitin increases histone acetylation, and promotes androgen independence in prostate tumours by increasing androgen receptor activation by adrenal androgens. Oncogene. 2012;31:4588-98 pubmed publisher |
| Minet A, Gaster M. The dynamic equilibrium between ATP synthesis and ATP consumption is lower in isolated mitochondria from myotubes established from type 2 diabetic subjects compared to lean control. Biochem Biophys Res Commun. 2011;409:591-5 pubmed publisher |
| Zhang J, Ye J, Altafaj A, Cardona M, Bahi N, Llovera M, et al. EndoG links Bnip3-induced mitochondrial damage and caspase-independent DNA fragmentation in ischemic cardiomyocytes. PLoS ONE. 2011;6:e17998 pubmed publisher |
- western blot; human; 1:150
| Yan Y, Xu H, Peng S, Zhao W, Wang B. Proteome analysis of ultraviolet-B-induced protein expression in vitro human dermal fibroblasts. Photodermatol Photoimmunol Photomed. 2010;26:318-26 pubmed publisher |
| Theiss A, Laroui H, Obertone T, Chowdhury I, Thompson W, Merlin D, et al. Nanoparticle-based therapeutic delivery of prohibitin to the colonic epithelial cells ameliorates acute murine colitis. Inflamm Bowel Dis. 2011;17:1163-76 pubmed publisher |
| Lee H, Arnouk H, Sripathi S, Chen P, Zhang R, Bartoli M, et al. Prohibitin as an oxidative stress biomarker in the eye. Int J Biol Macromol. 2010;47:685-90 pubmed publisher |
- immunocytochemistry; human; 1:50
- western blot; human; 1:200
| Sperandio S, Poksay K, Schilling B, Crippen D, Gibson B, Bredesen D. Identification of new modulators and protein alterations in non-apoptotic programmed cell death. J Cell Biochem. 2010;111:1401-12 pubmed publisher |
- immunohistochemistry; rat; 1:100
- western blot; rat; 1:500
| Shen Q, Xu H, Wei L, Chen J, Liu H. Intrauterine growth restriction and postnatal high-protein diet affect the kidneys in adult rats. Nutrition. 2011;27:364-71 pubmed publisher |
| Sofiadis A, Dinets A, Orre L, Branca R, Juhlin C, Foukakis T, et al. Proteomic study of thyroid tumors reveals frequent up-regulation of the Ca2+ -binding protein S100A6 in papillary thyroid carcinoma. Thyroid. 2010;20:1067-76 pubmed publisher |
| Liu H, Hsu P, Lai M, Chang H, Ho C, Cheng H, et al. An unusual function of RON receptor tyrosine kinase as a transcriptional regulator in cooperation with EGFR in human cancer cells. Carcinogenesis. 2010;31:1456-64 pubmed publisher |
| Sassi N, De Marchi U, Fioretti B, Biasutto L, Gulbins E, Franciolini F, et al. An investigation of the occurrence and properties of the mitochondrial intermediate-conductance Ca2+-activated K+ channel mtKCa3.1. Biochim Biophys Acta. 2010;1797:1260-7 pubmed publisher |
- immunoprecipitation; mouse
- immunocytochemistry; mouse; 1:50
- western blot; mouse
| Jain R, Ghoshal A, Mandal C, Shaha C. Leishmania cell surface prohibitin: role in host-parasite interaction. Cell Microbiol. 2010;12:432-52 pubmed publisher |
- immunohistochemistry; human; 1:100
- western blot; human; 1:200
| He Q, Zhang S, Chu Y, Jia X, Zhao L, Wang X. Separation and identification of differentially expressed nuclear matrix proteins in breast carcinoma forming. Acta Oncol. 2010;49:76-84 pubmed publisher |
- immunocytochemistry; human; 1:300
- western blot; human; 1:1000
| Shi S, Li Q, Liu Q, Xu D, Tang J, Liang Y, et al. Nuclear matrix protein, prohibitin, was down-regulated and translocated from nucleus to cytoplasm during the differentiation of osteosarcoma MG-63 cells induced by ginsenoside Rg1, cinnamic acid, and tanshinone IIA (RCT). J Cell Biochem. 2009;108:926-34 pubmed publisher |
- western blot; mouse
- western blot; human
| Theiss A, Jenkins A, Okoro N, Klapproth J, Merlin D, Sitaraman S. Prohibitin inhibits tumor necrosis factor alpha-induced nuclear factor-kappa B nuclear translocation via the novel mechanism of decreasing importin alpha3 expression. Mol Biol Cell. 2009;20:4412-23 pubmed publisher |
| Rothfuss O, Fischer H, Hasegawa T, Maisel M, Leitner P, Miesel F, et al. Parkin protects mitochondrial genome integrity and supports mitochondrial DNA repair. Hum Mol Genet. 2009;18:3832-50 pubmed publisher |
| Proulx D, Aubin E, Lemieux R, Bazin R. Spontaneous internalization of IVIg in activated B cells. Immunol Lett. 2009;124:18-26 pubmed publisher |
| De Marchi U, Sassi N, Fioretti B, Catacuzzeno L, Cereghetti G, Szabo I, et al. Intermediate conductance Ca2+-activated potassium channel (KCa3.1) in the inner mitochondrial membrane of human colon cancer cells. Cell Calcium. 2009;45:509-16 pubmed publisher |
- western blot; human; 1:400
| Zhang Z, Jia L, Feng Y, Zheng W. Overexpression of follicle-stimulating hormone receptor facilitates the development of ovarian epithelial cancer. Cancer Lett. 2009;278:56-64 pubmed publisher |
| Chuang Y, Chen S, Liou C, Lin T, Chang W, Chan S, et al. Contribution of nitric oxide, superoxide anion, and peroxynitrite to activation of mitochondrial apoptotic signaling in hippocampal CA3 subfield following experimental temporal lobe status epilepticus. Epilepsia. 2009;50:731-46 pubmed publisher |
- western blot; Hepacivirus C; 1:1000
| Nitahara Kasahara Y, Fukasawa M, Shinkai Ouchi F, Sato S, Suzuki T, Murakami K, et al. Cellular vimentin content regulates the protein level of hepatitis C virus core protein and the hepatitis C virus production in cultured cells. Virology. 2009;383:319-27 pubmed publisher |
- western blot; mouse; 1:1000
| Da Cruz S, Martinou J. Purification and proteomic analysis of the mouse liver mitochondrial inner membrane. Methods Mol Biol. 2008;432:101-16 pubmed publisher |
- immunohistochemistry; human
| Vesela K, Hulkova H, Hansikova H, Zeman J, Elleder M. Structural analysis of tissues affected by cytochrome C oxidase deficiency due to mutations in the SCO2 gene. APMIS. 2008;116:41-9 pubmed publisher |
- western blot; mouse; 1:500
| Schmidt V, Chiariello C, Capilla E, Miller F, Bahou W. Development of hepatocellular carcinoma in Iqgap2-deficient mice is IQGAP1 dependent. Mol Cell Biol. 2008;28:1489-502 pubmed publisher |
- immunohistochemistry; human; 1:500
| Sikora J, Dvorakova L, Vlaskova H, Stolnaja L, Betlach J, Spacek J, et al. A case of excessive autophagocytosis with multiorgan involvement and low clinical penetrance. Cesk Patol. 2007;43:93-103 pubmed |
| Wu T, Wu H, Wang Y, Chang T, Chan S, Lin Y, et al. Prohibitin in the pathogenesis of transitional cell bladder cancer. Anticancer Res. 2007;27:895-900 pubmed |
| Chuang Y, Chen S, Lin T, Liou C, Chang W, Chan S, et al. Upregulation of nitric oxide synthase II contributes to apoptotic cell death in the hippocampal CA3 subfield via a cytochrome c/caspase-3 signaling cascade following induction of experimental temporal lobe status epilepticus in the rat. Neuropharmacology. 2007;52:1263-73 pubmed |
| Chan J, Cheng H, Chou J, Li F, Dai K, Chan S, et al. Heat shock protein 60 or 70 activates nitric-oxide synthase (NOS) I- and inhibits NOS II-associated signaling and depresses the mitochondrial apoptotic cascade during brain stem death. J Biol Chem. 2007;282:4585-600 pubmed |
- western blot; chicken; 1:400
| Pucci B, Adams C, Fertala J, Snyder B, Mansfield K, Tafani M, et al. Development of the terminally differentiated state sensitizes epiphyseal chondrocytes to apoptosis through caspase-3 activation. J Cell Physiol. 2007;210:609-15 pubmed |
- immunohistochemistry; human; 1:100
- immunocytochemistry; rat; 1:100
- western blot; rat; 1:1000
| Guo W, Xu H, Chen J, Yang Y, Jin J, Fu R, et al. Prohibitin suppresses renal interstitial fibroblasts proliferation and phenotypic change induced by transforming growth factor-beta1. Mol Cell Biochem. 2007;295:167-77 pubmed |
- immunohistochemistry; human; 1:500
| Sikora J, Harzer K, Elleder M. Neurolysosomal pathology in human prosaposin deficiency suggests essential neurotrophic function of prosaposin. Acta Neuropathol. 2007;113:163-75 pubmed |
- chromatin immunoprecipitation; human
| Joshi B, Rastogi S, Morris M, Carastro L, DeCook C, Seto E, et al. Differential regulation of human YY1 and caspase 7 promoters by prohibitin through E2F1 and p53 binding sites. Biochem J. 2007;401:155-66 pubmed |
| Tsintzas K, Jewell K, Kamran M, Laithwaite D, Boonsong T, Littlewood J, et al. Differential regulation of metabolic genes in skeletal muscle during starvation and refeeding in humans. J Physiol. 2006;575:291-303 pubmed |
| Chang A, Chan J, Chou J, Li F, Dai K, Chan S. Heat shock protein 60 in rostral ventrolateral medulla reduces cardiovascular fatality during endotoxaemia in the rat. J Physiol. 2006;574:547-64 pubmed |
| Chan H, Gharbi S, Gaffney P, Cramer R, Waterfield M, Timms J. Proteomic analysis of redox- and ErbB2-dependent changes in mammary luminal epithelial cells using cysteine- and lysine-labelling two-dimensional difference gel electrophoresis. Proteomics. 2005;5:2908-26 pubmed |
| Suzuki R, Sakamoto S, Tsutsumi T, Rikimaru A, Tanaka K, Shimoike T, et al. Molecular determinants for subcellular localization of hepatitis C virus core protein. J Virol. 2005;79:1271-81 pubmed |
- western blot; human; fig 5
| Li Q, Ching A, Chan B, Chow S, Lim P, Ho T, et al. A death receptor-associated anti-apoptotic protein, BRE, inhibits mitochondrial apoptotic pathway. J Biol Chem. 2004;279:52106-16 pubmed |
| Manjunath L, Singh A, Sahoo S, Mishra A, Padmarajan J, Basavaraju C, et al. Stop codon read-through of mammalian MTCH2 leading to an unstable isoform regulates mitochondrial membrane potential. J Biol Chem. 2020;295:17009-17026 pubmed publisher |
| Li X, Chai R, Chen G, Zhang L, Tan Tai W, Shi H, et al. Prohibitin (PHB) interacts with AKT in mitochondria to coordinately modulate sperm motility. Asian J Androl. 2020;22:583-589 pubmed publisher |
| Ludwig A, de Miroschedji K, Doeppner T, Börger V, Ruesing J, Rebmann V, et al. Precipitation with polyethylene glycol followed by washing and pelleting by ultracentrifugation enriches extracellular vesicles from tissue culture supernatants in small and large scales. J Extracell Vesicles. 2018;7:1528109 pubmed publisher |
| Anderson C, Kahl A, Qian L, Stepanova A, Starkov A, Manfredi G, et al. Prohibitin is a positive modulator of mitochondrial function in PC12 cells under oxidative stress. J Neurochem. 2018;146:235-250 pubmed publisher |
| Yarmishyn A, Kremenskoy M, Batagov A, Preuss A, Wong J, Kurochkin I. Genome-wide analysis of mRNAs associated with mouse peroxisomes. BMC Genomics. 2016;17:1028 pubmed publisher |
| Wakatsuki S, Tokunaga S, Shibata M, Araki T. GSK3B-mediated phosphorylation of MCL1 regulates axonal autophagy to promote Wallerian degeneration. J Cell Biol. 2017;216:477-493 pubmed publisher |
| Ullmann R, Morbini P, Halbwedl I, Bongiovanni M, Gogg Kammerer M, Papotti M, et al. Protein expression profiles in adenocarcinomas and squamous cell carcinomas of the lung generated using tissue microarrays. J Pathol. 2004;203:798-807 pubmed |
| Thompson W, Ramalho Santos J, Sutovsky P. Ubiquitination of prohibitin in mammalian sperm mitochondria: possible roles in the regulation of mitochondrial inheritance and sperm quality control. Biol Reprod. 2003;69:254-60 pubmed |
