NY-BR-1 Monoclonal Antibody (NY-BR-1 No. 2) | Invitrogen MA5-12645 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

NY-BR-1 Monoclonal Antibody (NY-BR-1 No. 2)

catalog :

MA5-12645

quantity :

1 mL

price :

US 1156.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

NY-BR-1 No. 2

reactivity :

human

application :

immunohistochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 1

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human	Woodard A, Yu J, Dabbs D, Beriwal S, Florea A, Elishaev E, et al. NY-BR-1 and PAX8 immunoreactivity in breast, gynecologic tract, and other CK7+ carcinomas: potential use for determining site of origin. Am J Clin Pathol. 2011;136:428-35 pubmed publisher

image

image 1 :

Formalin-fixed paraffin-embedded metastatic breast ca to lymph node stained with NY-BR-1 antibody using peroxidase conjugate and DAB chromogen. Note: cytoplasmic and occasional nuclear staining

product information

Product Type :

Antibody

Product Name :

NY-BR-1 Monoclonal Antibody (NY-BR-1 No. 2)

Catalog # :

MA5-12645

Quantity :

1 mL

Price :

US 1156.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human

Applications :

Immunohistochemistry (Frozen): 1:100, Immunohistochemistry (Paraffin): 1:100

Species :

Human

Clone :

NY-BR-1 No. 2

Isotype :

IgG1, kappa

Storage :

4° C

Description :

NY-BR-1 is a novel differentiation marker predominantly expressed in normal breast and breast cancer. It has been shown by Immunohistochemistry (IHC) that NY-BR-1 was present solely in ductal epithelium of normal breast tissue. Invasive carcinoma of the breast and carcinoma in situ were positive for NY-BR-1, whereas most other tumors and normal tissues are negative, with the exceptions of one-third of sweat gland carcinomas and around two percent of prostate carcinoma. NY-BR-1 is reported to express more frequently in estrogen-positive and lymph node-negative primary carcinomas, and more commonly in grade 1 than in grade 2 or grade 3. In a study by Varga et al (2006) forty-nine percent of lymph node metastasis were shown to be positive.

Immunogen :

A 77 aa peptide from human NYBR-1 protein

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Frozen): 1:100, Immunohistochemistry (Paraffin): 1:100

Aliases :

ANKRD30A; ankyrin repeat domain 30A; ankyrin repeat domain-containing protein 30A; breast cancer antigen NY-BR-1; NY-BR-1; serologically defined breast cancer antigen NY-BR-1

more info or order :

Invitrogen product webpage