This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CA125 Monoclonal Antibody (M11)
catalog :
MA5-12425
quantity :
500µL
price :
US 475.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
M11
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
citations: 8
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human; 1:1000
Simons M, Nagtegaal I, Overbeek L, Flucke U, Massuger L, Bulten J. A patient with a noninvasive mucinous ovarian borderline tumor presenting with late pleural metastases. Int J Gynecol Pathol. 2015;34:143-50 pubmed publisher
  • western blot; human; 1:3000
Woodward A, Mauris J, Argueso P. Binding of transmembrane mucins to galectin-3 limits herpesvirus 1 infection of human corneal keratinocytes. J Virol. 2013;87:5841-7 pubmed publisher
  • western blot; human; 1:3000
Woodward A, Senchyna M, Williams R, ARGUESO P. Characterization of the interaction between hydroxypropyl guar galactomannan and galectin-3. Biochem Biophys Res Commun. 2012;424:12-7 pubmed publisher
  • western blot; human; 1:3000
Guzman Aranguez A, Woodward A, Pintor J, ARGUESO P. Targeted disruption of core 1 ?1,3-galactosyltransferase (C1galt1) induces apical endocytic trafficking in human corneal keratinocytes. PLoS ONE. 2012;7:e36628 pubmed publisher
  • western blot; human
Bravo Osuna I, Noiray M, Briand E, Woodward A, Argueso P, Molina Martínez I, et al. Interfacial interaction between transmembrane ocular mucins and adhesive polymers and dendrimers analyzed by surface plasmon resonance. Pharm Res. 2012;29:2329-40 pubmed publisher
  • western blot; human
Govindarajan B, Menon B, Spurr Michaud S, Rastogi K, Gilmore M, ARGUESO P, et al. A metalloproteinase secreted by Streptococcus pneumoniae removes membrane mucin MUC16 from the epithelial glycocalyx barrier. PLoS ONE. 2012;7:e32418 pubmed publisher
  • western blot; human
Davies J, Wickström C, Thornton D. Gel-forming and cell-associated mucins: preparation for structural and functional studies. Methods Mol Biol. 2012;842:27-47 pubmed publisher
  • western blot; human
Xiong L, Woodward A, ARGUESO P. Notch signaling modulates MUC16 biosynthesis in an in vitro model of human corneal and conjunctival epithelial cell differentiation. Invest Ophthalmol Vis Sci. 2011;52:5641-6 pubmed publisher
product information
Product Type :
Antibody
Product Name :
CA125 Monoclonal Antibody (M11)
Catalog # :
MA5-12425
Quantity :
500µL
Price :
US 475.00
Clonality :
Monoclonal
Host :
Mouse
Reactivity :
Human
Applications :
Immunocytochemistry: 1:250, Immunofluorescence: 1:250, Immunohistochemistry (Paraffin): 1:20-1:40
Species :
Human
Clone :
M11
Isotype :
IgG1, kappa
Storage :
4° C
Description :
CA 125 determinant is present on a high molecular weight, mucin like glycoprotein of high molecular weight. CA 125 has been found on frozen sections of amnion and derivatives of coelomic and mullerian epithelium, including pleura, pericardium and peritoneum. In adult tissues, epithelial cells of fallopian tube, endometrium and endocervix; pancreas, colon, gall bladder, stomach, kidney, apocrine sweat gland and mammary gland. It is also found in mesothelial cell lining of pleura, pericardium and peritoneum. It is found in ovarian tumors of serous, endometrioid or clear cell types and adenocarcinomas of mullerian type.
Immunogen :
CA 125 antigen derived from ascites fluid
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 1:250, Immunofluorescence: 1:250, Immunohistochemistry (Paraffin): 1:20-1:40
Aliases :
CA-125, CA125 ovarian cancer antigen, MUC-16, mucin-16, ovarian cancer-related tumor marker CA125, ovarian carcinoma antigen CA125
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
www.thermofisher.com
800-678-5599
headquarters: USA