CD68 Monoclonal Antibody (PG-M1) | Invitrogen MA5-12407 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD68 Monoclonal Antibody (PG-M1)

catalog :

MA5-12407

quantity :

500 µL

price :

US 395.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

PG-M1

reactivity :

human, mouse

application :

immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 16

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; human; 1:200; loading ...	Li H, Shen P, Liang Y, Zhang F. Fibroblastic reticular cell tumor of the breast: A case report and review of the literature. Exp Ther Med. 2016;11:561-564 pubmed
immunohistochemistry; human; 1:150	Rocchiccioli S, Pelosi G, Rosini S, Marconi M, Viglione F, Citti L, et al. Secreted proteins from carotid endarterectomy: an untargeted approach to disclose molecular clues of plaque progression. J Transl Med. 2013;11:260 pubmed publisher
immunohistochemistry - paraffin section; human; 1:100; tbl 2	Qiu S, Wei X, Huang W, Wu M, Qin Y, Li Y, et al. Diagnostic and therapeutic strategy and the most efficient prognostic factors of breast malignant fibrous histiocytoma. Sci Rep. 2013;3:2529 pubmed publisher
immunohistochemistry; mouse; 1:100	Hsiao Y, Li C, Chi J, Tseng J, Chang Y, Hsu L, et al. CCAAT/enhancer binding protein δ in macrophages contributes to immunosuppression and inhibits phagocytosis in nasopharyngeal carcinoma. Sci Signal. 2013;6:ra59 pubmed publisher
immunohistochemistry; human; 1:100	Yin W, Li J, Chan J. Sporadic haemangioblastoma of the kidney with rhabdoid features and focal CD10 expression: report of a case and literature review. Diagn Pathol. 2012;7:39 pubmed publisher
immunohistochemistry; human; 0.2 ng/ml	Peterson S, Poposki J, Nagarkar D, Chustz R, Peters A, Suh L, et al. Increased expression of CC chemokine ligand 18 in patients with chronic rhinosinusitis with nasal polyps. J Allergy Clin Immunol. 2012;129:119-27.e1-9 pubmed publisher
immunohistochemistry - paraffin section; human; 1:50; tbl 2	West N, Panet Raymond V, Truong P, Alexander C, Babinszky S, Milne K, et al. Intratumoral Immune Responses Can Distinguish New Primary and True Recurrence Types of Ipsilateral Breast Tumor Recurrences (IBTR). Breast Cancer (Auckl). 2011;5:105-15 pubmed publisher
immunohistochemistry; human; 24 ng/mL	Poposki J, Uzzaman A, Nagarkar D, Chustz R, Peters A, Suh L, et al. Increased expression of the chemokine CCL23 in eosinophilic chronic rhinosinusitis with nasal polyps. J Allergy Clin Immunol. 2011;128:73-81.e4 pubmed publisher
immunohistochemistry; human; 1:100	Behzatoglu K, Durak H, Canberk S, Aydin O, Huq G, Oznur M, et al. Giant cell tumor-like lesion of the urinary bladder: a report of two cases and literature review; giant cell tumor or undifferentiated carcinoma?. Diagn Pathol. 2009;4:48 pubmed publisher
immunohistochemistry; human	Liu B, Li L, Gao M, Wang Y, Yu J. Microinflammation is involved in the dysfunction of arteriovenous fistula in patients with maintenance hemodialysis. Chin Med J (Engl). 2008;121:2157-61 pubmed
immunohistochemistry; human	Yuri T, Yamazaki F, Takasu K, Shikata N, Tsubura A. Glomeruloid hemangioma. Pathol Int. 2008;58:390-5 pubmed publisher
immunohistochemistry; human; 1:100	Hammes L, Tekmal R, Naud P, Edelweiss M, Kirma N, Valente P, et al. Macrophages, inflammation and risk of cervical intraepithelial neoplasia (CIN) progression--clinicopathological correlation. Gynecol Oncol. 2007;105:157-65 pubmed
immunocytochemistry; human; 1.0 ug/ml	Tian Y, Kelemen S, Autieri M. Inhibition of AIF-1 expression by constitutive siRNA expression reduces macrophage migration, proliferation, and signal transduction initiated by atherogenic stimuli. Am J Physiol Cell Physiol. 2006;290:C1083-91 pubmed
	Hoffmann D, Dvorakova T, Stroobant V, Bouzin C, Daumerie A, Solvay M, et al. Tryptophan 2,3-Dioxygenase Expression Identified in Human Hepatocellular Carcinoma Cells and in Intratumoral Pericytes of Most Cancers. Cancer Immunol Res. 2020;8:19-31 pubmed publisher
	Salvadori C, Svara T, Rocchigiani G, Millanta F, Pavlin D, Cemazar M, et al. Effects of Electrochemotherapy with Cisplatin and Peritumoral IL-12 Gene Electrotransfer on Canine Mast Cell Tumors: a Histopathologic and Immunohistochemical Study. Radiol Oncol. 2017;51:286-294 pubmed publisher
	Pothoven K, Norton J, Suh L, Carter R, Harris K, Biyasheva A, et al. Neutrophils are a major source of the epithelial barrier disrupting cytokine oncostatin M in patients with mucosal airways disease. J Allergy Clin Immunol. 2017;139:1966-1978.e9 pubmed publisher

image

image 1 :

Formalin-fixed, paraffin-embedded human tonsil stained with CD68 using peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of macrophage

product information

Product Type :

Antibody

Product Name :

CD68 Monoclonal Antibody (PG-M1)

Catalog # :

MA5-12407

Quantity :

500 µL

Price :

US 395.00

Clonality :

Monoclonal

Host :

Mouse

Reactivity :

Human

Applications :

Immunohistochemistry (Paraffin): 1:50-1:100

Species :

Human

Clone :

PG-M1

Isotype :

IgG3, kappa

Storage :

4° C

Description :

CD68 (Macrosialin) is a 110 kDa integral membrane glycoprotein predominantly expressed on the intracellular lysomsomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes. Also, CD68 could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 is expressed by interdigitating reticulum cells in tonsil and some histiocytic lymphoma or histiocytosis, acute myeloid leukemia (AML), and granulocytic sarcoma. Elevated expression of CD68 has been demonstrated on CD34+ cells in various human malignancies, including several Acute Myeloid Leukemia studies.

Immunogen :

Gaucher cells

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1:50-1:100

Aliases :

CD68; CD68 antigen; CD68 molecule; GP110; Lamp4; macrophage antigen CD68; macrosialin; Scard1; scavenger receptor class D, member 1; similar to CD68 antigen

more info or order :

Invitrogen product webpage