CD138 Monoclonal Antibody (MI15) | Invitrogen MA5-12400 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD138 Monoclonal Antibody (MI15)

catalog :

MA5-12400

quantity :

500 µL

price :

US 406.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

MI15

reactivity :

human, rat, rhesus macaque

application :

western blot, immunohistochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 8

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; human; 1:50; fig 4a	Rodríguez Lorenzo S, Konings J, van der Pol S, Kamermans A, Amor S, van Horssen J, et al. Inflammation of the choroid plexus in progressive multiple sclerosis: accumulation of granulocytes and T cells. Acta Neuropathol Commun. 2020;8:9 pubmed publisher
immunohistochemistry; rhesus macaque	Phuah J, Mattila J, Lin P, Flynn J. Activated B cells in the granulomas of nonhuman primates infected with Mycobacterium tuberculosis. Am J Pathol. 2012;181:508-14 pubmed publisher
immunohistochemistry; human	Svec A, Rangaiah M, Giles M, Jaksa R, McAulay K. EBV+ diffuse large B-cell lymphoma arising within atrial myxoma. An example of a distinct primary cardiac EBV+ DLBCL of immunocompetent patients. Pathol Res Pract. 2012;208:172-6 pubmed publisher
immunohistochemistry; human; 1:100	Yu G, Qu G, Kong L, Pan X, Wang W, Lv J. Primary myoepithelial carcinoma of the larynx: case report and review of the literature. Pathol Res Pract. 2011;207:127-30 pubmed publisher
immunohistochemistry; human	Zurac S, Girtan M, Lavric L, Petsakos G, Staniceanu F, Bastian A, et al. Local immune alterations in oral mucosa of the edentulous patients; possible cause of teeth loss?. Rom J Intern Med. 2008;46:249-53 pubmed
immunohistochemistry; human; 1:50	Pap Z, Pávai Z, Dénes L, Kovalszky I, Jung J. An immunohistochemical study of colon adenomas and carcinomas: E-cadherin, Syndecan-1, Ets-1. Pathol Oncol Res. 2009;15:579-87 pubmed publisher
immunohistochemistry; human	Martin D, Boersma B, Yi M, Reimers M, Howe T, Yfantis H, et al. Differences in the tumor microenvironment between African-American and European-American breast cancer patients. PLoS ONE. 2009;4:e4531 pubmed publisher
	Kumar Singh A, Shrinet J, Parniewska M, Fuxe J, Dobra K, Hjerpe A. Mapping the Interactome of the Nuclear Heparan Sulfate Proteoglycan Syndecan-1 in Mesothelioma Cells. Biomolecules. 2020;10: pubmed publisher

image

image 1 :

Formalin-fixed, paraffin-embedded human tonsil stained with CD138 antibody using peroxidase-conjugate and AEC chromogen. Note membrane staining of plasma cells.

product information

Product Type :

Antibody

Product Name :

CD138 Monoclonal Antibody (MI15)

Catalog # :

MA5-12400

Quantity :

500 µL

Price :

US 406.00

Clonality :

Monoclonal

Host :

Mouse

Reactivity :

Human, Rat

Applications :

Flow Cytometry: 1:2, Immunohistochemistry (Paraffin): 1:10-1:20, Immunoprecipitation: Assay-dependent, Western Blot: 1:100-1:500

Species :

Human, Rat

Clone :

MI15

Isotype :

IgG1, kappa

Storage :

4° C

Description :

CD138 (syndecan 1) is a transmembrane proteoglycan that can bind a variety of cytokines and modulate their activity, as well as the activity of extracellular matrix components and influence many developmental processes. CD138 is expressed mainly in differentiating keratinocytes and is transiently upregulated in all layers of the epidermis upon tissue injury. It is also highly expressed on plasma cells and can be detected even on fibroblasts, vascular smooth muscle cells and endothelial cells. Up-regulation and down-regulation of CD138 on the cell surface often correlates with the gain of cancerous characteristics. Serum levels of the shedded soluble sCD138 are used as a prognostic factor of cancerogenesis.

Immunogen :

U-266 cells

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:2, Immunohistochemistry (Paraffin): 1:10-1:20, Immunoprecipitation: Assay-dependent, Western Blot: 1:100-1:500

Aliases :

AA408134; AA409076; CD antigen 138; CD138; CD138 antigen; heparan sulfate proteoglycan fibroblast growth factor receptor; HSPG; sCD138; SDC; Sdc1; soluble CD138; Sstn; syn-1; Synd; SYND1; Synd-1; SYNDECA; syndecan; syndecan 1; syndecan proteoglycan 1; Syndecan1; syndecan-1; synstatin

more info or order :

Invitrogen product webpage