EXO1 Monoclonal Antibody (266) | Invitrogen MA5-12262 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

EXO1 Monoclonal Antibody (266)

catalog :

MA5-12262

quantity :

500 µL

price :

US 450.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

266

reactivity :

human, mouse

application :

western blot, immunoprecipitation

citations: 6

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:200	O Sullivan R, Arnoult N, Lackner D, Oganesian L, Haggblom C, Corpet A, et al. Rapid induction of alternative lengthening of telomeres by depletion of the histone chaperone ASF1. Nat Struct Mol Biol. 2014;21:167-74 pubmed publisher
immunoprecipitation; mouse western blot; mouse	Izumchenko E, Saydi J, Brown K. Exonuclease 1 (Exo1) is required for activating response to S(N)1 DNA methylating agents. DNA Repair (Amst). 2012;11:951-64 pubmed publisher
immunoprecipitation; human western blot; human	Sertic S, Pizzi S, Cloney R, Lehmann A, Marini F, Plevani P, et al. Human exonuclease 1 connects nucleotide excision repair (NER) processing with checkpoint activation in response to UV irradiation. Proc Natl Acad Sci U S A. 2011;108:13647-52 pubmed publisher
western blot; human	El Shemerly M, Hess D, Pyakurel A, Moselhy S, Ferrari S. ATR-dependent pathways control hEXO1 stability in response to stalled forks. Nucleic Acids Res. 2008;36:511-9 pubmed
western blot; human	El Shemerly M, Janscak P, Hess D, Jiricny J, Ferrari S. Degradation of human exonuclease 1b upon DNA synthesis inhibition. Cancer Res. 2005;65:3604-9 pubmed
	Lu H, Saha J, Beckmann P, Hendrickson E, Davis A. DNA-PKcs promotes chromatin decondensation to facilitate initiation of the DNA damage response. Nucleic Acids Res. 2019;47:9467-9479 pubmed publisher

product information

Product Type :

Antibody

Product Name :

EXO1 Monoclonal Antibody (266)

Catalog # :

MA5-12262

Quantity :

500 µL

Price :

US 450.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human, Mouse

Applications :

Western Blot: 1-2 µg/mL

Species :

Human, Mouse

Clone :

266

Isotype :

IgG1, kappa

Storage :

4° C

Description :

Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Required for muscle atrophy following denervation.

Immunogen :

Recombinant full length mouse Exo1 protein

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1-2 µg/mL

Aliases :

5730442G03Rik; Exo1; EXOI; Exonuclease 1; exonuclease I; HEX1; hExo1; hExoI; mExo1; Msa; rad2 nuclease family member, homolog of S. cerevisiae exonuclease 1