This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Calprotectin Monoclonal Antibody (MAC387)
catalog :
MA5-12213
quantity :
500 µL
price :
US 395.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
MAC387
reactivity :
African green monkey, guinea pig, crab eating macaque, human, mouse, rat, dogs, pigs , cat
application :
immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section
citations: 25
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; crab eating macaque; loading ...; fig 4e
Wonderlich E, Swan Z, Bissel S, Hartman A, Carney J, O Malley K, et al. Widespread Virus Replication in Alveoli Drives Acute Respiratory Distress Syndrome in Aerosolized H5N1 Influenza Infection of Macaques. J Immunol. 2017;198:1616-1626 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:500; fig 1
Ambe P, Orth V, Gödde D, Zirngibl H. Improving the Preoperative Diagnostic Accuracy of Acute Appendicitis. Can Fecal Calprotectin Be Helpful?. PLoS ONE. 2016;11:e0168769 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:500; fig 2
Ambe P, Gödde D, Bönicke L, Papadakis M, Störkel S, Zirngibl H. Calprotectin could be a potential biomarker for acute appendicitis. J Transl Med. 2016;14:107 pubmed publisher
  • flow cytometry; African green monkey; loading ...
Phuah J, Wong E, Gideon H, Maiello P, Coleman M, Hendricks M, et al. Effects of B Cell Depletion on Early Mycobacterium tuberculosis Infection in Cynomolgus Macaques. Infect Immun. 2016;84:1301-1311 pubmed publisher
  • immunohistochemistry - paraffin section; pigs ; 1:400
Elgharably H, Ganesh K, Dickerson J, Khanna S, Abas M, Ghatak P, et al. A modified collagen gel dressing promotes angiogenesis in a preclinical swine model of chronic ischemic wounds. Wound Repair Regen. 2014;22:720-9 pubmed publisher
  • immunohistochemistry; pigs
Wu C, Qiu H, Hu X, Ruan Y, Tian Y, Chu Y, et al. Short-term safety and efficacy of the biodegradable iron stent in mini-swine coronary arteries. Chin Med J (Engl). 2013;126:4752-7 pubmed
  • immunohistochemistry; pigs ; 1:100
Nedorost L, Uemura H, Furck A, Saeed I, Slavik Z, Kobr J, et al. Vascular histopathologic reaction to pulmonary artery banding in an in vivo growing porcine model. Pediatr Cardiol. 2013;34:1652-60 pubmed publisher
  • immunohistochemistry; human; 1:200
Gahremanpour A, Vela D, Zheng Y, Silva G, Fodor W, Cardoso C, et al. Xenotransplantation of human unrestricted somatic stem cells in a pig model of acute myocardial infarction. Xenotransplantation. 2013;20:110-22 pubmed publisher
  • immunohistochemistry; pigs
Lu M, Zhao S, Liu Q, Jiang S, Song P, Qian H, et al. Transplantation with autologous mesenchymal stem cells after acute myocardial infarction evaluated by magnetic resonance imaging: an experimental study. J Thorac Imaging. 2012;27:125-35 pubmed publisher
  • flow cytometry; rat
Gauglitz G, Toliver Kinsky T, Williams F, Song J, Cui W, Herndon D, et al. Insulin increases resistance to burn wound infection-associated sepsis. Crit Care Med. 2010;38:202-8 pubmed publisher
  • immunohistochemistry; human; 1:200
Kapucuoglu N, Percinel S, Ventura T, Lang R, Al Daraji W, Eusebi V. Dendritic cell sarcomas/tumours of the breast: report of two cases. Virchows Arch. 2009;454:333-9 pubmed publisher
  • immunohistochemistry; dogs
Poutahidis T, Doulberis M, Karamanavi E, Angelopoulou K, Koutinas C, Papazoglou L. Primary gastric choriocarcinoma in a dog. J Comp Pathol. 2008;139:146-50 pubmed publisher
  • immunohistochemistry; pigs
Song P, Zhang H, Lu M, Li J, Liu X, Wei Y, et al. Role of cardiopulmonary bypass and arrested heart status in the early cell distribution after intracoronary infusion of bone marrow stromal cells. J Surg Res. 2009;153:66-70 pubmed publisher
  • immunohistochemistry; pigs
Zhang H, Song P, Tang Y, Zhang X, Zhao S, Wei Y, et al. Injection of bone marrow mesenchymal stem cells in the borderline area of infarcted myocardium: heart status and cell distribution. J Thorac Cardiovasc Surg. 2007;134:1234-40 pubmed
  • immunohistochemistry; mouse
Kimura Y, Sumiyoshi M, Kawahira K, Sakanaka M. Effects of ginseng saponins isolated from Red Ginseng roots on burn wound healing in mice. Br J Pharmacol. 2006;148:860-70 pubmed
  • immunohistochemistry; pigs
Dor F, Gollackner B, Kuwaki K, Ko D, Cooper D, Houser S. Histopathology of spleen allograft rejection in miniature swine. Int J Exp Pathol. 2005;86:57-66 pubmed
Wilkinson A, Hulme S, Kennedy J, Mann E, Horn P, Shepherd E, et al. The senescent secretome drives PLVAP expression in cultured human hepatic endothelial cells to promote monocyte transmigration. iScience. 2023;26:107966 pubmed publisher
Du Cheyne C, Martens A, De Spiegelaere W. High Numbers of CD163-Positive Macrophages in the Fibrotic Region of Exuberant Granulation Tissue in Horses. Animals (Basel). 2021;11: pubmed publisher
Kammerman M, Bera A, Wu R, Harrison S, Maxwell C, Lundquist K, et al. Molecular Insight into TdfH-Mediated Zinc Piracy from Human Calprotectin by Neisseria gonorrhoeae. MBio. 2020;11: pubmed publisher
Linard C, Brachet M, Strup Perrot C, l Homme B, Busson E, Squiban C, et al. Autologous Bone Marrow Mesenchymal Stem Cells Improve the Quality and Stability of Vascularized Flap Surgery of Irradiated Skin in Pigs. Stem Cells Transl Med. 2018;7:569-582 pubmed publisher
Zhu Y, Xing H, Dai D, Kallmes D, Kadirvel R. Differential Interstrain Susceptibility to Vertebrobasilar Dolichoectasia in a Mouse Model. AJNR Am J Neuroradiol. 2017;38:611-616 pubmed publisher
Godman J, Burns T, Kelly C, Watts M, Leise B, Schroeder E, et al. The effect of hypothermia on influx of leukocytes in the digital lamellae of horses with oligofructose-induced laminitis. Vet Immunol Immunopathol. 2016;178:22-8 pubmed publisher
Gestrich C, Duerr G, Heinemann J, Meertz A, Probst C, Roell W, et al. Activation of Endocannabinoid System Is Associated with Persistent Inflammation in Human Aortic Aneurysm. Biomed Res Int. 2015;2015:456582 pubmed publisher
Hayenga H, Hu J, Meyer C, Wilson E, Hein T, Kuo L, et al. Differential progressive remodeling of coronary and cerebral arteries and arterioles in an aortic coarctation model of hypertension. Front Physiol. 2012;3:420 pubmed publisher
Yorozuya M, Suzuki H, Iso Y, Shibata M, Nakatani M, Koba S, et al. Comparison of the morphological changes of restenosis after the implantation of various types of stents in a swine model. Coron Artery Dis. 2002;13:305-12 pubmed
product information
Product Type :
Antibody
Product Name :
Calprotectin Monoclonal Antibody (MAC387)
Catalog # :
MA5-12213
Quantity :
500 µL
Price :
US 395.00
Clonality :
Monoclonal
Purity :
Protein G
Host :
Mouse
Reactivity :
Canine, Feline, Guinea Pig, Human, Mouse, Non-human primate, Porcine, Rat
Applications :
Immunohistochemistry (Paraffin): 1:1,000
Species :
Canine, Feline, Guinea Pig, Human, Mouse, Non-human primate, Porcine, Rat
Clone :
MAC387
Isotype :
IgG1
Storage :
4° C
Description :
The S100A8/A9 heterocomplex, also called MRP-8/MRP-14 complex or calprotectin, comprises 60% of the cytoplasmic protein fraction of circulating polymorphonuclear granulocytes and is also found in monocytes, macrophages and ileal tissue eosinophils. Peripheral blood monocytes carry the antigen extra- and intracellularly, neutrophils only intracellularly. The S100A8/A9 complex has antibacterial, antifungal, immunomodulating and antiproliferative effects. Besides this it is a potent chemotactic factor for neutrophils. Plasma concentrations are elevated in diseases associated with increased neutrophil activity, like inflammatory bowel disease. Granulocytes terminate their existence after transmigration through the intestinal wall. Therefore calprotectin is also detectable in feces. Elevated levels of calprotectin have been observed in body fluids such as plasma, saliva, gingival crevicular fluid, stools, and synovial fluid during infection and inflammatory conditions.
Immunogen :
Affinity purified monocyte membrane preparation
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry (Paraffin): 1:1,000
Aliases :
60B8Ag; AI323541; AW546964; B8Ag; BEE11; BEE22; CAGA; CAGB; calcium binding protein; S100 protein; calgranulin A; calgranulin B; calgranulin-A; Calgranulin-B; calprotectin; calprotectin L1H subunit; Calprotectin L1L subunit; CFAG; CGLA; CGLB; chemotactic cytokine CP-10; chemotactic S100 protein; CP-10; Cystic fibrosis antigen; EGK_01322; EGK_21438; GAGB; intracellular calcium-binding protein (MRP14); L1AG; Leukocyte L1 complex heavy chain; leukocyte L1 complex light chain; LIAG; LOC100735514; LOC532569 protein; MA387; MAC387; macrophage migration inhibitory factor-related protein-14; macrophage migration inhibitory factor-related protein-8; MIF; migration inhibitory factor-related protein 14; Migration inhibitory factor-related protein 8; Mrp14; MRP-14; MRP8; MRP-8; myeloid-related protein 14; Neutrophil cytosolic 23 kDa protein; neutrophil cytosolic 7 kDa protein; NIF; p14; p23; P7; p8; Pro-inflammatory S100 cytokine; protein S100-A8; Protein S100-A9; S100 calcium binding protein A8; S100 calcium binding protein A8 (calgranulin A); S100 calcium binding protein A9; S100 calcium binding protein A9 (calgranulin B); S100 calcium binding protein A9; protein S100-A9; S100 calcium-binding protein A8; S100 calcium-binding protein A8 (calgranulin A); S100 calcium-binding protein A9; S100 calcium-binding protein A9 (calgranulin B); S100a8; S100A8/S100A9; S100a9; similar to Calgranulin A (Migration inhibitory factor-related protein 8) (MRP-8) (Cystic fibrosis antigen) (CFAG) (P8) (Leukocyte L1 complex light chain) (S100 calcium-binding protein A8) (Calprotectin L1L subunit) (Urinary stone protein band A). ; urinary stone protein band A
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA