Epstein Barr Virus Antibody Cocktail | Invitrogen MA5-12172 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Epstein Barr Virus Antibody Cocktail

catalog :

MA5-12172

quantity :

500 µL

price :

US 460

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

CS1, CS2, CS3, CS4

application :

immunohistochemistry, immunohistochemistry - paraffin section

citations: 1

Reference
Kurth J, Hansmann M, Rajewsky K, Kuppers R. Epstein-Barr virus-infected B cells expanding in germinal centers of infectious mononucleosis patients do not participate in the germinal center reaction. Proc Natl Acad Sci U S A. 2003;100:4730-5 pubmed

product information

Product Type :

Antibody

Product Name :

Epstein Barr Virus Antibody Cocktail

Catalog # :

MA5-12172

Quantity :

500 µL

Price :

US 460

Clonality :

Cocktail

Host :

Mouse

Reactivity :

Virus

Applications :

Immunohistochemistry (Paraffin): 1:25-1:50

Species :

Virus

Clone :

CS1, CS2, CS3, CS4

Isotype :

IgG1, kappa

Storage :

4° C

Description :

Epstein-Barr virus (EBV) is a human herpes virus, which is associated with conditions such as Hodgkin's disease and Burkitt's Lymphoma and is the causative agent in mononucleosis in adolescents. EBV latently infects B lymphocytes. Infected B cells express EBV nuclear antigens and latent proteins LMP1, LMP2A and LMP2B. LMP2A forms aggregates in the plasma membranes of B lymphocytes, where it functions as a negative regulator of the Src and Syk protein tyrosine kinases. Studies show that LMP2A blocks B-cell receptor (BCR) signal transduction in EBV immortalized B cells in vitro and may play an important role in maintaining a latent EBV infection within the peripheral blood B cells of infected individuals.EBNA-1 is the only viral protein consistently expressed in all malignancies associated with EBV.

Immunogen :

EBV-encoded recombinant latent membrane protein

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1:25-1:50

Aliases :

EBV