GRB2 Monoclonal Antibody (2GB04 (C1.4)) | Invitrogen MA5-12165 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

GRB2 Monoclonal Antibody (2GB04 (C1.4))

catalog :

MA5-12165

quantity :

500 uL

price :

US 474.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2GB04 (C1.4)

reactivity :

human, mouse, rat, bovine, Xenopus laevis

application :

immunohistochemistry, immunohistochemistry - paraffin section

citations: 1

Reference
Galperin E, Sorkin A. Endosomal targeting of MEK2 requires RAF, MEK kinase activity and clathrin-dependent endocytosis. Traffic. 2008;9:1776-90 pubmed publisher

product information

Product Type :

Antibody

Product Name :

GRB2 Monoclonal Antibody (2GB04 (C1.4))

Catalog # :

MA5-12165

Quantity :

500 uL

Price :

US 474.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Bovine, Human, Mouse, Rat, Xenopus laevis

Applications :

Immunohistochemistry (Paraffin): 1-2 ug/mL

Species :

Bovine, Human, Mouse, Rat, Xenopus laevis

Clone :

2GB04 (C1.4)

Isotype :

IgG1, kappa

Storage :

4 C

Description :

GRB 2 protein contains one SH2 domain flanked on both sides by an SH3 domain. In response to EGF, GRB 2 binds, through its SH3 domains, to the guanine nucleotide exchange factor, Sos. The GRB 2-Sos complex then binds the EGF receptor. These interactions play a critical role in the activation of the p21 ras signaling pathway.

Immunogen :

Purified recombinant human Grb2 protein

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1-2 ug/mL

Aliases :

AA408164; abundant SRC homology; adapter protein GRB2; Adapter protein GRB2-A; ASH; ASH protein; EGFRBP-GRB2; epidermal growth factor receptor-binding protein GRB2; grb2; grb2.L; grb2-a; grb2-b; Grb3-3; growth factor receptor bound protein 2; growth factor receptor bound protein 2 L homeolog; growth factor receptor-bound protein 2; Growth factor receptor-bound protein 2-A; growth factor receptor-bound protein 3; HT027; hypothetical protein LOC535298; MST084; MSTP084; NCKAP2; OTTHUMP00000166097; OTTHUMP00000166098; protein Ash; SH2/SH3 adapter GRB2; SH2/SH3 adapter GRB2-A; SH2/SH3 adaptor Grb2; XELAEV_18044055mg