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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Cytokeratin 7 Monoclonal Antibody (OV-TL 12/30)
catalog :
MA5-11986
quantity :
500 µL
price :
US 510.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
OV-TL 12/30
reactivity :
Japanese rice fish, human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 59
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 4b
Dai J, Cimino P, Gouin K, Grzelak C, Barrett A, Lim A, et al. Astrocytic laminin-211 drives disseminated breast tumor cell dormancy in brain. Nat Cancer. 2022;3:25-42 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 2c
Hankeova S, Salplachta J, Zikmund T, Kavkova M, Van Hul N, Brinek A, et al. DUCT reveals architectural mechanisms contributing to bile duct recovery in a mouse model for Alagille syndrome. elife. 2021;10: pubmed publisher
  • immunocytochemistry; mouse; fig s4e
Yang Y, Liu B, Xu J, Wang J, Wu J, Shi C, et al. Derivation of Pluripotent Stem Cells with In Vivo Embryonic and Extraembryonic Potency. Cell. 2017;169:243-257.e25 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:5000; loading ...; fig 3b
Sammar M, Siwetz M, Meiri H, Fleming V, Altevogt P, Huppertz B. Expression of CD24 and Siglec-10 in first trimester placenta: implications for immune tolerance at the fetal-maternal interface. Histochem Cell Biol. 2017;147:565-574 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:300; loading ...; tbl 2
Xia Q, Wang Z, Chen N, Gan H, Teng X, Shi S, et al. Xp11.2 translocation renal cell carcinoma with NONO-TFE3 gene fusion: morphology, prognosis, and potential pitfall in detecting TFE3 gene rearrangement. Mod Pathol. 2017;30:416-426 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:200; tbl 2
Hsieh M, Wang H, Lee Y, Ko J, Chang Y. Reevaluation of MAML2 fusion-negative mucoepidermoid carcinoma: a subgroup being actually hyalinizing clear cell carcinoma of the salivary gland with EWSR1 translocation. Hum Pathol. 2017;61:9-18 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:200; fig 4
  • western blot; human; 1:2000; fig 4
Fleury H, Communal L, Carmona E, Portelance L, Arcand S, Rahimi K, et al. Novel high-grade serous epithelial ovarian cancer cell lines that reflect the molecular diversity of both the sporadic and hereditary disease. Genes Cancer. 2015;6:378-398 pubmed
  • immunohistochemistry; human; tbl 2
Sauter J, Ambaye A, Mount S. Increased utilization, verification, and clinical implications of immunocytochemistry: Experience in a northern New England hospital. Diagn Cytopathol. 2015;43:688-95 pubmed publisher
  • immunohistochemistry - paraffin section; human
Chen Q, Gu Y, Liu B. Clinicopathological characteristics of kidney mucinous tubular and spindle cell carcinoma. Int J Clin Exp Pathol. 2015;8:1007-12 pubmed
  • immunohistochemistry; human
Le Page C, Köbel M, de Ladurantaye M, Rahimi K, Madore J, Babinszky S, et al. Specimen quality evaluation in Canadian biobanks participating in the COEUR repository. Biopreserv Biobank. 2013;11:83-93 pubmed publisher
  • immunohistochemistry; human; 1:50
Panni R, Sanford D, Belt B, Mitchem J, Worley L, Goetz B, et al. Tumor-induced STAT3 activation in monocytic myeloid-derived suppressor cells enhances stemness and mesenchymal properties in human pancreatic cancer. Cancer Immunol Immunother. 2014;63:513-28 pubmed publisher
  • immunohistochemistry; human; 0.2 ug/ml
König J, Lang I, Siwetz M, Fröhlich J, Huppertz B. Amnion-derived mesenchymal stromal cells show a mesenchymal-epithelial phenotype in culture. Cell Tissue Bank. 2014;15:193-8 pubmed publisher
  • immunocytochemistry; human; 1:100
Fu S, Dong L, Sun W, Xu Y, Gao L, Miao Y. Stromal-epithelial crosstalk provides a suitable microenvironment for the progression of ovarian cancer cells in vitro. Cancer Invest. 2013;31:616-24 pubmed publisher
  • immunohistochemistry; human; 1:100
Schneider S, Kloimstein P, Pammer J, Brannath W, Grasl M, Erovic B. New diagnostic markers in salivary gland tumors. Eur Arch Otorhinolaryngol. 2014;271:1999-2007 pubmed publisher
  • immunohistochemistry; human; 1:100
Li H, Chen L, Zhang M, Tang S, Fu X. Three-dimensional culture and identification of human eccrine sweat glands in matrigel basement membrane matrix. Cell Tissue Res. 2013;354:897-902 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:150; tbl 1
Li X, Feng Y, Wei W, Liu P, Xie Z, Wang J, et al. Signet-ring cell carcinoma of the breast: a case report. World J Surg Oncol. 2013;11:183 pubmed publisher
  • immunohistochemistry; human
Gurzu S, Szentirmay Z, Toth E, Bara T, Jung I. Serrated pathway adenocarcinomas: molecular and immunohistochemical insights into their recognition. PLoS ONE. 2013;8:e57699 pubmed publisher
  • immunohistochemistry; human; 1:150
Kahveci R, Gürer B, Kaygusuz G, Sekerci Z. Miliary brain metastases from occult lung adenocarcinoma: Radiologic and histopathologic confirmation. J Neurosci Rural Pract. 2012;3:386-9 pubmed publisher
  • immunohistochemistry; human; 1:300
Erovic B, Kim D, Cassol C, Goldstein D, Irish J, Asa S, et al. Prognostic and predictive markers in medullary thyroid carcinoma. Endocr Pathol. 2012;23:232-42 pubmed publisher
  • immunohistochemistry; human; 1:800
Kim J, Lee C, Park W, Kim J, Kim A, Shin N, et al. Adenocarcinoma with sarcomatous dedifferentiation arising from mature cystic teratoma of the anterior mediastinum. Pathol Res Pract. 2012;208:741-5 pubmed publisher
  • immunohistochemistry; human; 1:300
Erovic B, Harris L, Jamali M, Goldstein D, Irish J, Asa S, et al. Biomarkers of parathyroid carcinoma. Endocr Pathol. 2012;23:221-31 pubmed publisher
  • immunohistochemistry; human
  • western blot; human
Létourneau I, Quinn M, Wang L, Portelance L, Caceres K, Cyr L, et al. Derivation and characterization of matched cell lines from primary and recurrent serous ovarian cancer. BMC Cancer. 2012;12:379 pubmed publisher
  • immunohistochemistry; human
Zhou Z, Yang G, Zhou J, Yu M. Significance of TRIM29 and β-catenin expression in non-small-cell lung cancer. J Chin Med Assoc. 2012;75:269-74 pubmed publisher
  • immunohistochemistry; human; 1:300
Erovic B, Al Habeeb A, Harris L, Goldstein D, Kim D, Ghazarian D, et al. Identification of novel target proteins in sebaceous gland carcinoma. Head Neck. 2013;35:642-8 pubmed publisher
  • immunohistochemistry; human
Gurzu S, Jung I. Aberrant pattern of the cytokeratin 7/cytokeratin 20 immunophenotype in colorectal adenocarcinomas with BRAF mutations. Pathol Res Pract. 2012;208:163-6 pubmed publisher
  • western blot; Japanese rice fish
Saxena S, Singh S, Lakshmi M, Meghah V, Bhatti B, Swamy C, et al. Proteomic analysis of zebrafish caudal fin regeneration. Mol Cell Proteomics. 2012;11:M111.014118 pubmed publisher
  • immunohistochemistry; human; 1:50
Bayrak R, Haltas H, Yenidunya S. The value of CDX2 and cytokeratins 7 and 20 expression in differentiating colorectal adenocarcinomas from extraintestinal gastrointestinal adenocarcinomas: cytokeratin 7-/20+ phenotype is more specific than CDX2 antibody. Diagn Pathol. 2012;7:9 pubmed publisher
  • immunohistochemistry; human; 1:200
Giordano G, Pizzi S, Berretta R, D Adda T. A new case of primary signet-ring cell carcinoma of the cervix with prominent endometrial and myometrial involvement: Immunohistochemical and molecular studies and review of the literature. World J Surg Oncol. 2012;10:7 pubmed publisher
  • immunohistochemistry; human; fig 4
Errasti Murugarren E, Diaz P, Godoy V, Riquelme G, Pastor Anglada M. Expression and distribution of nucleoside transporter proteins in the human syncytiotrophoblast. Mol Pharmacol. 2011;80:809-17 pubmed publisher
  • immunohistochemistry; human; 1:500
Sarsik B, Simsir A, Karaarslan S, Sen S. Mucinous tubular and spindle cell carcinoma of kidney and problems in diagnosis. Turk Patoloji Derg. 2011;27:116-26 pubmed publisher
  • immunohistochemistry; human; 1:100
Ustun H, Astarci H, Sungu N, Ozdemir A, Ekinci C. Primary malignant deciduoid peritoneal mesothelioma: a report of the cytohistological and immunohistochemical appearances. Diagn Cytopathol. 2011;39:402-8 pubmed publisher
  • immunohistochemistry; human
Giovannoni I, Santorelli F, Candusso M, Di Rocco M, Bellacchio E, Callea F, et al. Two novel mutations in African and Asian children with progressive familial intrahepatic cholestasis type 3. Dig Liver Dis. 2011;43:567-70 pubmed publisher
  • immunohistochemistry; human
Nikitina L, Ahammer H, Blaschitz A, Gismondi A, Glasner A, Schimek M, et al. A new method for morphometric analysis of tissue distribution of mobile cells in relation to immobile tissue structures. PLoS ONE. 2011;6:e15086 pubmed publisher
  • immunohistochemistry; human; 1:3000
Moser G, Orendi K, Gauster M, Siwetz M, Helige C, Huppertz B. The art of identification of extravillous trophoblast. Placenta. 2011;32:197-9 pubmed publisher
  • immunohistochemistry; human; 1:100
Mukhopadhyay S, Katzenstein A. Subclassification of non-small cell lung carcinomas lacking morphologic differentiation on biopsy specimens: Utility of an immunohistochemical panel containing TTF-1, napsin A, p63, and CK5/6. Am J Surg Pathol. 2011;35:15-25 pubmed publisher
  • immunohistochemistry; human; 1:100
Huang S, Xu Y, Wu C, Sha D, Fu X. In vitro constitution and in vivo implantation of engineered skin constructs with sweat glands. Biomaterials. 2010;31:5520-5 pubmed publisher
  • immunohistochemistry; human; 1:200
Behzatoglu K, Durak H, Canberk S, Aydin O, Huq G, Oznur M, et al. Giant cell tumor-like lesion of the urinary bladder: a report of two cases and literature review; giant cell tumor or undifferentiated carcinoma?. Diagn Pathol. 2009;4:48 pubmed publisher
  • immunohistochemistry; human; 1:200
Sati L, Seval Celik Y, Demir R. Lung surfactant proteins in the early human placenta. Histochem Cell Biol. 2010;133:85-93 pubmed publisher
  • immunohistochemistry; mouse; 1:100
Botelho M, Oliveira P, Gomes J, Gartner F, Lopes C, da Costa J, et al. Tumourigenic effect of Schistosoma haematobium total antigen in mammalian cells. Int J Exp Pathol. 2009;90:448-53 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:5000
  • immunocytochemistry; human; 1:5000
Gauster M, Siwetz M, Huppertz B. Fusion of villous trophoblast can be visualized by localizing active caspase 8. Placenta. 2009;30:547-50 pubmed publisher
  • immunohistochemistry; human; 1:100
Li H, Zhou G, Fu X, Zhang L. Antigen expression of human eccrine sweat glands. J Cutan Pathol. 2009;36:318-24 pubmed publisher
  • immunohistochemistry; human
  • western blot; human
Ouellet V, Zietarska M, Portelance L, Lafontaine J, Madore J, Puiffe M, et al. Characterization of three new serous epithelial ovarian cancer cell lines. BMC Cancer. 2008;8:152 pubmed publisher
  • immunohistochemistry; human; 1:200
Buyukkurt S, Altintas A, Gumurdulu D, Zeren H, Guzel B. Mucoepidermoid carcinoma of the parotid gland with ovarian and peritoneal metastasis. J Obstet Gynaecol Res. 2008;34:271-3 pubmed publisher
  • immunohistochemistry; human; 1:100
Akbulut M, Zekioglu O, Terek M, Ozdemir N. Chondromatous differentiation in clear cell carcinoma of the ovary: a rare finding challenging the differential diagnosis. Arch Gynecol Obstet. 2008;278:569-72 pubmed publisher
  • immunohistochemistry; human; 1:100
Sati L, Demir A, Sarikcioglu L, Demir R. Arrangement of collagen fibers in human placental stem villi. Acta Histochem. 2008;110:371-9 pubmed publisher
  • immunocytochemistry; human
Duret C, Gerbal Chaloin S, Ramos J, Fabre J, Jacquet E, Navarro F, et al. Isolation, characterization, and differentiation to hepatocyte-like cells of nonparenchymal epithelial cells from adult human liver. Stem Cells. 2007;25:1779-90 pubmed
  • immunohistochemistry; human; 1:100
Lee G, Kang J, Kim H, Lee J, Lee J, Jang J. Combination chemotherapy with gemcitabine and cisplatin as first-line treatment for immunohistochemically proven cholangiocarcinoma. Am J Clin Oncol. 2006;29:127-31 pubmed
  • immunohistochemistry; human
Yesim G, Gupse T, Zafer U, Ahmet A. Mesenchymal hamartoma of the liver in adulthood: immunohistochemical profiles, clinical and histopathological features in two patients. J Hepatobiliary Pancreat Surg. 2005;12:502-7 pubmed
R xfc land L, Andreatta F, Massalini S, Chuva de Sousa Lopes S, Clevers H, Hendriks D, et al. Organoid models of fibrolamellar carcinoma mutations reveal hepatocyte transdifferentiation through cooperative BAP1 and PRKAR2A loss. Nat Commun. 2023;14:2377 pubmed publisher
Michalik M, Wieczorek P, Czekaj P. In Vitro Differentiation of Human Amniotic Epithelial Cells into Hepatocyte-like Cells. Cells. 2022;11: pubmed publisher
Bergmann S, Penfold C, Slatery E, Siriwardena D, Drummer C, Clark S, et al. Spatial profiling of early primate gastrulation in utero. Nature. 2022;609:136-143 pubmed publisher
Mircea M, Hochane M, Fan X, Chuva de Sousa Lopes S, Garlaschelli D, Semrau S. Phiclust: a clusterability measure for single-cell transcriptomics reveals phenotypic subpopulations. Genome Biol. 2022;23:18 pubmed publisher
Abou Monsef Y, Kutsal O. Immunohistochemical evaluation of hepatic progenitor cells in different types of feline liver diseases. J Vet Med Sci. 2021;83:613-621 pubmed publisher
Johansson H, Svensson J, Almström M, Van Hul N, Rudling M, Angelin B, et al. Regulation of bile acid metabolism in biliary atresia: reduction of FGF19 by Kasai portoenterostomy and possible relation to early outcome. J Intern Med. 2020;287:534-545 pubmed publisher
Grundy L, Caldwell A, Garcia Caraballo S, Erickson A, Schober G, Castro J, et al. Histamine induces peripheral and central hypersensitivity to bladder distension via the histamine H1 receptor and TRPV1. Am J Physiol Renal Physiol. 2020;318:F298-F314 pubmed publisher
Pinheiro C, Roque R, Adriano A, Mendes P, Praça M, Reis I, et al. Optimization of immunocytochemistry in cytology: comparison of two protocols for fixation and preservation on cytospin and smear preparations. Cytopathology. 2015;26:38-43 pubmed publisher
Ullmann R, Morbini P, Halbwedl I, Bongiovanni M, Gogg Kammerer M, Papotti M, et al. Protein expression profiles in adenocarcinomas and squamous cell carcinomas of the lung generated using tissue microarrays. J Pathol. 2004;203:798-807 pubmed
Sonzogni A, Colloredo G, Fabris L, Cadamuro M, Paris B, Roffi L, et al. Isolated idiopathic bile ductular hyperplasia in patients with persistently abnormal liver function tests. J Hepatol. 2004;40:592-8 pubmed
Barbareschi M, Murer B, Colby T, Chilosi M, Macri E, Loda M, et al. CDX-2 homeobox gene expression is a reliable marker of colorectal adenocarcinoma metastases to the lungs. Am J Surg Pathol. 2003;27:141-9 pubmed
image
image 1 :
Invitrogen MA5-11986 image 1
Formalin-fixed, paraffin-embedded human ovarian carcinoma stained with Keratin 7 antibody using peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of tumor cells.
product information
Product Type :
Antibody
Product Name :
Cytokeratin 7 Monoclonal Antibody (OV-TL 12/30)
Catalog # :
MA5-11986
Quantity :
500 µL
Price :
US 510.00
Clonality :
Monoclonal
Purity :
Protein A/G
Host :
Mouse
Reactivity :
Human
Applications :
Immunocytochemistry: 2 µg/mL, Immunohistochemistry (Paraffin): 1:100-1:200, Western Blot: 1:1,000
Species :
Human
Clone :
OV-TL 12/30
Isotype :
IgG1, kappa
Storage :
4° C
Description :
Cytokeratin 7 blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7).
Immunogen :
OTN II ovarian carcinoma cell line
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 2 µg/mL, Immunohistochemistry (Paraffin): 1:100-1:200, Western Blot: 1:1,000
Aliases :
CK7; CK-7; Cytokeratin 7; cytokeratin-7; D15Wsu77e; K2C7; K7; Kb7; keratin 7; keratin 7, type II; keratin associated protein 7.1; keratin complex 2, basic, gene 7; keratin, 55K type II cytoskeletal; keratin, simple epithelial type I, K7; keratin, type II cytoskeletal 7; Keratin-7; keratin-associated protein 7-1; keratin-associated protein 7-1-like protein; Krt2-7; KRT7; krt7 {ECO:0000250; LOC100755511; LOC100861181; NACHT, LRR and PYD domains-containing protein 3; sarcolectin; SCL; si:ch73-233m11.1; si:ch73-233m11.2; similar to keratin 7; type II keratin Kb7; type II mesothelial keratin K7; type-II keratin Kb7; UniProtKB:P08729}
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA