Growth Hormone Antibody Cocktail | Invitrogen MA5-11926 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Growth Hormone Antibody Cocktail

catalog :

MA5-11926

quantity :

500 µL

price :

US 436

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

GH01 (#2), GH02 (#7)

reactivity :

human

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

citations: 2

Published Application/Species/Sample/Dilution	Reference
western blot; human	Amin N, Zheng Y, Kesavapany S, Kanungo J, Guszczynski T, Sihag R, et al. Cyclin-dependent kinase 5 phosphorylation of human septin SEPT5 (hCDCrel-1) modulates exocytosis. J Neurosci. 2008;28:3631-43 pubmed publisher
	Peculis R, Mandrika I, Petrovska R, Dortane R, Megnis K, Nazarovs J, et al. Pituispheres Contain Genetic Variants Characteristic to Pituitary Adenoma Tumor Tissue. Front Endocrinol (Lausanne). 2020;11:313 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Growth Hormone Antibody Cocktail

Catalog # :

MA5-11926

Quantity :

500 µL

Price :

US 436

Clonality :

Cocktail

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

Immunohistochemistry (Paraffin): 1:2000-1:4000, Western Blot: 1-2 µg/mL

Species :

Human

Clone :

GH01 (#2), GH02 (#7)

Isotype :

IgG2a, kappa

Storage :

4° C

Description :

Human growth hormone (hGH) is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The GH1 gene, along with 4 additional related genes, is located at the growth hormone locus on chromosome 17. The five genes share a remarkably high degree of sequence identity. Alternative splicing results in 5 isoforms ranging from approximately 19 kDa to 24 kDa. HGH is produced by the somatotroph cells in the pituitary. It acts through binding to membrane receptors that belong to the cytokine receptor subfamily. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. Mutations or deletions in the gene lead to growth hormone deficiency and short stature.

Immunogen :

Purified recombinant human growth hormone

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1:2000-1:4000, Western Blot: 1-2 µg/mL

Aliases :

Gh; GH1; GHB5; GHN; GH-N; Growth hormone; growth hormone 1; growth hormone 12; growth hormone B5; growth hormone precursor; HGH; hGH-N; IGHD1B; Pituitary growth hormone; RNGHGP; Somatotropin